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  1. 1661
    “…Oilseed rape is characterized by a low nitrogen remobilization efficiency during leaf senescence, mainly due to a lack of proteolysis. Because cotyledons are subjected to senescence, it was hypothesized that contrasting protease activities between genotypes may be distinguishable early in the senescence of cotyledons. …”
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    Proteomic Investigations of Proteases Involved in Cotyledon Senescence: A Model to Explore the Genotypic Variability of Proteolysis Machinery Associated with Nitrogen Remobilization Efficiency during the Leaf Senescence of Oilseed Rape
  2. 1662
    “…The transplantation of non-senescent and senescent A375 cells together into nude mice showed accelerated tumour growth compared with transplanting non-senescent cells alone; no tumours developed when transplanting senescent cells alone. …”
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    Senescence-associated secretory factors induced by cisplatin in melanoma cells promote non-senescent melanoma cell growth through activation of the ERK1/2-RSK1 pathway
  3. 1663
    “…Cells in senescence cease proliferation; however, it has been demonstrated that colonies that are formed from cells escaping senescence appear in drug-induced senescence; however, the conditions influencing the emergence of such senescence-escaping cells (SECs) remain unclear. …”
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    Occurrence of senescence-escaping cells in doxorubicin-induced senescence is enhanced by PD0332991, a cyclin-dependent kinase 4/6 inhibitor, in colon cancer HCT116 cells
  4. 1664
    “…The signaling stimulated cell senescence, senescence-related secretion of TGF-β1 and IL-11 and production of collagen 1 by pulmonary fibroblasts and the epithelial-to-mesenchymal transition of AT2 cells. …”
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    TGF-β1/IL-11/MEK/ERK signaling mediates senescence-associated pulmonary fibrosis in a stress-induced premature senescence model of Bmi-1 deficiency
  5. 1665
    “…The presence of senescent cells is associated with renal fibrosis. …”
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    Albumin-induced premature senescence in human renal proximal tubular cells and its relationship with intercellular fibrosis: Effect of premature senescence stimulated by albumin on fibrosis in HK-2 cells
  6. 1666
    “…Cellular senescence modulated focal adhesion size and composition. …”
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    Dissecting the influence of cellular senescence on cell mechanics and extracellular matrix formation in vitro
  7. 1667
    “…Emerging evidence suggests that cellular senescence contributes importantly to AD pathophysiology, although the mechanisms underlying brain cell senescence and by which senescent cells promote neuro-pathophysiology remain unclear. …”
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    Aging, Plasminogen Activator Inhibitor 1, Brain Cell Senescence, and Alzheimer’s Disease
  8. 1668
    “…RESULTS: We identified two distinct senescence-associated subtypes, noted low senescence CC1 and high senescence CC2. …”
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    Tumor senescence leads to poor survival and therapeutic resistance in human breast cancer
  9. 1669
    “…CONCLUSION: Although asymptomatic HIV/Leish subjects had normal and similar CD4+ and CD8+ T cells counts, their CD8(+)T cells had increased activation, senescence, and exhaustion, which could contribute to risk of developing VL.…”
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    T-cell activation, senescence, and exhaustion in asymptomatic HIV/Leishmania infantum co-infection
  10. 1670
    “…To examine bystander effects of radiation-induced senescence, we further treated normal MSCs with senescence-associated EXOs (SA-EXOs). …”
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    Senescence-associated exosomes transfer miRNA-induced fibrosis to neighboring cells
  11. 1671
    “…Preclinical research has shown the involvement of the activation of cellular senescence-related mechanisms in natural aging and kidney injury. …”
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    Vitamin D, Cellular Senescence and Chronic Kidney Diseases: What Is Missing in the Equation?
  12. 1672
    “…SCCNVs are prepared by inducing senescence in cancer cells ex vivo and subsequently extruding the senescent cancer cells through nanoporous membranes. …”
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    Senescent cancer cell-derived nanovesicle as a personalized therapeutic cancer vaccine
  13. 1673
    “…Cellular senescence contributes to tissue homeostasis and age-related pathologies. …”
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    A stress-induced cilium-to-PML-NB route drives senescence initiation
  14. 1674
    “…Melatonin (MT) is a multipotent substance proven to delay leaf senescence. However, its potential mechanism in delaying leaf senescence induced by abiotic stress remains unclear. …”
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    Morphological and Physiological Mechanisms of Melatonin on Delaying Drought-Induced Leaf Senescence in Cotton
  15. 1675
    “…One cause may be the accumulation of senescent cells that secrete factors (senescence associated secretory phenotype, SASP) promoting fibrosis and inflammation. …”
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    The Uremic Toxin Indoxyl Sulfate Accelerates Senescence in Kidney Proximal Tubule Cells
  16. 1676
    por Maric, Aida
    Publicado 2023
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    Hit the acceleration petal: Methylation as a mediator of ethylene-induced petal senescence
  17. 1677
    “…Senescence is a state of enduring growth arrest triggered by sublethal cell damage. …”
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    Single-cell transcriptomic analysis uncovers diverse and dynamic senescent cell populations
  18. 1678
    “…Blockade of ceramide generation may explain autophagic default, resistance to apoptosis, and the onset of senescence.…”
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    Reduced sulfatide content in deferoxamine-induced senescent HepG2 cells
  19. 1679
    “…Despite not dividing, senescent cells acquire the ability to synthesize and secrete a plethora of bioactive molecules, a feature known as the senescence-associated secretory phenotype (SASP). …”
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    Palbociclib-Induced Cellular Senescence Is Modulated by the mTOR Complex 1 and Autophagy
  20. 1680
    “…To prioritize gene and protein candidates that may enable the selective identification and removal of senescent cells, we compared gene expression signatures from replicative senescent cells to transcriptomics and proteomics atlases of normal human tissues and cell types. …”
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    Computational screen to identify potential targets for immunotherapeutic identification and removal of senescence cells
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