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  1. 1681
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    Author Correction: Senescent cardiomyocytes contribute to cardiac dysfunction following myocardial infarction
  2. 1682
    “…Our analysis indicated that DS cells across various types and organs experienced senescence stresses from as early as the fetal stage. …”
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    Single‐cell landscape analysis reveals systematic senescence in mammalian Down syndrome
  3. 1683
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    Role of lncRNA MALAT1 in UVA-induced corneal endothelial senescence
  4. 1684
    “…Since mitochondrial stress represents a key trigger of cellular senescence, and senescence leads to the accumulation of abnormal mitochondria with impaired dynamics and hindered homeostasis, this review focuses on the beneficial potential of targeting mitochondria, so that strategies can be developed to manage adipose tissue senescence for the treatment of age-related metabolic disorders.…”
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    Physiological Approaches Targeting Cellular and Mitochondrial Pathways Underlying Adipose Organ Senescence
  5. 1685
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    CRISPR-based screening identifies XPO7 as a positive regulator of senescence
  6. 1686
    “…Here, we demonstrated an accumulation of cellular senescence in doxorubicin-treated ovaries through detecting p16 and p21 expression levels and senescence-associated β-galactosidase (SA-β-gal) activity as well as senescence-associated secretory phenotype (SASP) factors. …”
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    Increased cellular senescence in doxorubicin-induced murine ovarian injury: effect of senolytics
  7. 1687
    Publicado 2023
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    Corrigendum to: REST/NRSF deficiency impairs autophagy and leads to cellular senescence in neurons
  8. 1688
    “…One plausible source of this oxidative stress and inflammation is an increase in the abundance of senescent endothelial cells. Cellular senescence is a cell cycle arrest that occurs in response to various damaging stimuli. …”
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    Endothelial cell telomere dysfunction induces senescence and results in vascular and metabolic impairments
  9. 1689
    “…However, the medicinal components of Fuzi in treating vascular senescence (VS) and its potential mechanism remain unclear. …”
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    Discovery of deoxyandrographolide and its novel effect on vascular senescence by targeting HDAC1
  10. 1690
    “…Cellular senescence plays a pivotal role in wound healing. At the initiation of liver fibrosis regression, accumulated senescent cells were detected and genes of senescence were upregulated. …”
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    Cellular senescence primes liver fibrosis regression through Notch‐EZH2
  11. 1691
    “…Herein, we investigate whether Korean red ginseng (KRG) can inhibit PM(2.5)-induced senescence in skin keratinocytes. PM(2.5)-treated human keratinocyte cell lines and normal human epidermal keratinocytes showed characteristics of cellular senescence, including flat and enlarged forms; however, KRG suppressed them in both cell types. …”
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    Korean Red Ginseng Attenuates Particulate Matter-Induced Senescence of Skin Keratinocytes
  12. 1692
    “…The purpose of this study was to determine the presence of senescent cells and the effects of fisetin on cellular senescence in the brain and other vital organs in old sheep, a more translational model. …”
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    Effects of Fisetin Treatment on Cellular Senescence of Various Tissues and Organs of Old Sheep
  13. 1693
    “…The human genome is spatially and temporally organized in the nucleus as chromatin, and the dynamic structure of chromatin is closely related to genome functions. Cellular senescence characterized by an irreversible arrest of proliferation is accompanied by chromatin reorganisation in the nucleus during senescence. …”
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    CRISPR imaging reveals chromatin fluctuation at the centromere region related to cellular senescence
  14. 1694
    “…However, recent studies highlight that senescent cells might also alter the local tissue environment and concur to chronic inflammation and cancer risk by secreting inflammatory and matrix remodeling factors, acquiring a senescence-associated secretory phenotype (SASP). …”
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    Cell Survival, Death, and Proliferation in Senescent and Cancer Cells: the Role of (Poly)phenols
  15. 1695
    “…In this review, we examine the changes in MSC senescence as a result of aging, discuss the progress of research on mechanisms and signalling pathways of MSC senescence, and discuss possible rejuvenation strategies of aged MSCs to combat senescence and enhance the health and therapeutic potential of MSCs.…”
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    Mesenchymal Stem Cell Senescence during Aging:From Mechanisms to Rejuvenation Strategies
  16. 1696
    “…Therefore, it may not be robust to evaluate the kernel dehydration of maize according to leaf senescence conditions due to the weak correlation between kernel water content and leaf senescence characteristics.…”
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    Temporal and Spatial Dynamics of Organ Water Content in Maize with Different Senescence Types
  17. 1697
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    Efficient expansion and delayed senescence of hUC-MSCs by microcarrier–bioreactor system
  18. 1698
    “…In this study, we focused on senescence of tissue-resident cells as potential driver of disease. …”
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    Senescent fibro-adipogenic progenitors are potential drivers of pathology in inclusion body myositis
  19. 1699
    “…Senescent cells drive age-related tissue dysfunction partially through the induction of a chronic senescence-associated secretory phenotype (SASP)(1). …”
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    Apoptotic stress causes mtDNA release during senescence and drives the SASP
  20. 1700
    “…In the present study, we delineate the genome-wide redistribution of accessible chromatin regions that lead to broad transcriptome effects during senescence. We report that distinct senescence-activated accessibility regions (SAAs) are always distributed in H3K27ac-occupied enhancer regions, where they are responsible for elevated flanking senescence-associated secretory phenotype (SASP) expression and aberrant cellular signaling relevant to SASP secretion. …”
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    TEAD4 antagonizes cellular senescence by remodeling chromatin accessibility at enhancer regions
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