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  1. 1781
    “…We hypothesized that daily intake of nondigestible saccharides delays senescence onset through the improvement of intestinal microflora. …”
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    Daily Feeding of Fructooligosaccharide or Glucomannan Delays Onset of Senescence in SAMP8 Mice
  2. 1782
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    Upregulation of colonic luminal polyamines produced by intestinal microbiota delays senescence in mice
  3. 1783
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    HiJAK’d Signaling; the STAT3 Paradox in Senescence and Cancer Progression
  4. 1784
    por Kilic Eren, Mehtap, Tabor, Vedrana
    Publicado 2014
    “…Oncogene induced senescence (OIS) is a sustained anti-proliferative response acutely induced in primary cells via activation of mitogenic oncogenes such as Ras/BRAF. …”
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    The Role of Hypoxia Inducible Factor-1 Alpha in Bypassing Oncogene-Induced Senescence
  5. 1785
    “…We also provide an overview of the ubiquitin ligases and related enzymes involved in regulating senescence in plants.…”
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    Regulation of senescence under elevated atmospheric CO(2) via ubiquitin modification
  6. 1786
    “…Oxidative stress is recognized as a key factor in the induction of endothelial senescence and diabetic retinopathy. However, specific mechanisms involved in oxidative stress-induced endothelial senescence have not been elucidated. …”
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    Oxidative Stress Induces Endothelial Cell Senescence via Downregulation of Sirt6
  7. 1787
    por Schurich, Anna, Henson, Sian M.
    Publicado 2014
    “…Antigen-specific T cells can be compromised in two ways through the distinct processes of replicative senescence and exhaustion. Senescence is initiated by a DNA damage response whereas exhaustion triggers inhibitory receptors to dampen the immune response. …”
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    The Many Unknowns Concerning the Bioenergetics of Exhaustion and Senescence during Chronic Viral Infection
  8. 1788
    “…The proliferative defect of senescent T cells is reversed by blocking AMPK-TAB1-dependent p38 activation.…”
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    AMPK-TAB1 activated p38 drives human T cell senescence
  9. 1789
    “…The evolutionary theory of senescence posits that as the probability of extrinsic mortality increases with age, selection should favour early-life over late-life reproduction. …”
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    Early reproductive investment, senescence and lifetime reproductive success in female Asian elephants
  10. 1790
    “…BACKGROUND: Nodules play an important role in fixing atmospheric nitrogen for soybean growth. Premature senescence of nodules can negatively impact on nitrogen availability for plant growth and, as such, we need a better understanding of nodule development and senescence. …”
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    Cysteine protease and cystatin expression and activity during soybean nodule development and senescence
  11. 1791
    “…In annual plants with determinate growth, sugar accumulation signals high carbon availability once growth has ceased, resulting in senescence-dependent nutrient recycling to the seeds. …”
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    Adaptation to altitude affects the senescence response to chilling in the perennial plant Arabis alpina
  12. 1792
    “…Cellular senescence is a stable proliferation arrest that suppresses tumorigenesis. …”
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    HIRA orchestrates a dynamic chromatin landscape in senescence and is required for suppression of neoplasia
  13. 1793
    “…Large number of poplar senescence leaves may adversely affect the wheat. Therefore, the present study was performed to examine the effect of senescence poplar leaves on wheat germ and some other biochemical parameters. …”
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    Biochemical and Physiological Studies on the Effects of Senescence Leaves of Populus deltoides on Triticum vulgare
  14. 1794
    “…There was a dramatic increase in auxin levels with senescence in L. longiflorum but not in Lilium L.A. …”
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    Auxin involvement in tepal senescence and abscission in Lilium: a tale of two lilies
  15. 1795
    “…Inhibitors of NF-κB signaling and ceramide formation prevent methamphetamine-induced senescence and systemic inflammation in rats self-administering the drug, attenuating their health deterioration. …”
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    Methamphetamine Accelerates Cellular Senescence through Stimulation of De Novo Ceramide Biosynthesis
  16. 1796
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    Restricted loss of olivocochlear but not vestibular efferent neurons in the senescent gerbil (Meriones unguiculatus)
  17. 1797
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    Colorless Chlorophyll Catabolites in Senescent Florets of Broccoli (Brassica oleracea var. italica)
  18. 1798
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    Alteration in the Wnt microenvironment directly regulates molecular events leading to pulmonary senescence
  19. 1799
    por Pujol, Benoit
    Publicado 2015
    “…Senescence, the deterioration of morphological, physiological, and reproductive functions with age that ends with the death of the organism, was widely studied in plants. …”
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    Genes and quantitative genetic variation involved with senescence in cells, organs, and the whole plant
  20. 1800
    “…In this model, PMA induced arrest (step one of a senescence program), whereas constitutively active mTOR drove geroconversion (step two). …”
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    Tumor promoter-induced cellular senescence: cell cycle arrest followed by geroconversion
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