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  1. 1901
  2. 1902
    “…Taken together, these results show that senescence is a natural occurring process essential for early inner ear development.…”
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  3. 1903
    “…This later response is associated with increased cellular senescence and inhibition of transcriptional coactivator with PDZ-binding motif (TAZ). …”
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  4. 1904
    “…Ancient trees have very high scientific, economic and cultural values. The senescence of ancient trees is a new research area but is poorly understood. …”
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  5. 1905
    “…Senescence is an irreversible state of cell cycle arrest that can be triggered by multiple stimuli, such as oxygen reactive species and DNA damage. …”
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  6. 1906
  7. 1907
    “…As a classical cellular feature, disc cell senescence is reported to be closely related with disc cell senescence. …”
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  8. 1908
    “…Telomerase defers the onset of telomere shortening and cellular senescence by adding telomeric repeat DNA to chromosome ends, and its activation contributes to carcinogenesis. …”
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  9. 1909
  10. 1910
    “…Instead, we show that progenitor cells undergoing poor differentiation are characterized by senescence, inability to suppress p53/P16(INK4) and secretion of factors reducing adipogenesis in non-senescent cells. …”
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  11. 1911
    “…POLD1, the catalytic subunit of DNA Pol δ, plays an important role in DNA synthesis and DNA damage repair, and POLD1 is downregulated in replicative senescence and mediates cell aging. However, the mechanisms of age-related downregulation of POLD1 expression have not been elucidated. …”
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  12. 1912
    “…Here, we examined VSMC senescence in patients with MFS and explored the potential mechanisms that link VSMC senescence and TGF-β. …”
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  13. 1913
  14. 1914
  15. 1915
  16. 1916
    “…Furthermore, HA abrogated the anti-proliferative and pro-senescent effect of Imatinib without modifying the imatinib-induced apoptosis. …”
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  17. 1917
  18. 1918
    “…However, the effects of sesame lignans on age-related brain dysfunction are not clear and were thus investigated in the present study using a senescence-accelerated mouse (SAMP10). Two-month-old male SAMP10 mice were administrated a basal diet with 0% or 0.05% sesame lignans for two months, or with 0%, 0.02%, or 0.05% sesame lignans for 10 months and subjected to step-through passive avoidance tasks and forced swim tests. …”
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  19. 1919
    “…We aim to evaluate the impact of a major depressive episode on the Senescence-Associated Secretory Phenotype (SASP) index, a dynamic secretory molecular pattern indicative of cellular senescence. …”
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  20. 1920
    “…Despite growth suppression, senescent cancer cells promote tumor formation and recurrence by producing cytokines and growth factors; this state is designated as the senescence‐associated secretory phenotype. …”
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