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    “…Due to their postmitotic status, the potential for neurons to undergo senescence has historically received little attention. …”
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    por Brody, Samuel
    Publicado 1924
    “…The course of decline of vitality with age due to the process of senescence, when not complicated by the process of growth, follows a simple exponential law; that is the degree of vitality or of senescence (defining vitality as the reciprocal of senescence) at any moment is, regardless of age, a constant percentage of the degree of vitality or senescence of the preceding moment. …”
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    “…The difference in their long-term growth potential may be attributed to activation of cellular senescence pathways. The primary mediator of senescence in nevi appears to be p16. …”
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    por Schafer, Marissa
    Publicado 2022
    “…Cell senescence and inflammation are interconnected mediators of aging and age-related disease. …”
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    “…Cellular senescence plays an important role in organismal aging and age‐related diseases. …”
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    “…The biological role of senescence is complex, since both protective and harmful effects have been described for senescent cells. …”
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    “…Cellular senescence is a key component of human aging that can be induced by a range of stimuli, including DNA damage, cellular stress, telomere shortening, and the activation of oncogenes. …”
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    por Mao, Genxiang, Xu, Xiaogang
    Publicado 2020
    “…Exosomes are one type of small-cell extracellular vesicles (sEVs), which together with the senescence-associated secretory phenotype (SASP) mainly constitute the senescent microenvironment and perform remotely intercellular communication. …”
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    por Campisi, Judith
    Publicado 2020
    “…Senescent cells arrest proliferation, essentially permanently, and develop a complex multi-component senescence-associated secretory phenotype (SASP). …”
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    “…PURPOSE: To investigate senescent evidence in corneal endothelial cells (CECs) of the senescence-accelerated mouse (SAM), which is considered a suitable animal model for the further study of the senescent mechanism in CECs. …”
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    “…The senescent cells (including replicative senescence and stress-induced premature senescence) of all the tissues look alike. …”
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