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  1. 29561
    “…In addition, THPO concentrations increase in several critical diseases, such as acute cardiac ischemia and sepsis, thus representing a potential diagnostic and prognostic biomarker. …”
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    Thrombopoietin participates in platelet activation in COVID-19 patients
  2. 29562
    “…Respiratory decompensation and sepsis were more frequently seen in obese patients, but pairwise comparisons were unable to reveal statistical significance. …”
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    LBSUN130 A Single Center Prospective Observational Cohort Study On The Association Of Asia Pacific Classification Of Body Mass Index, Waist Circumference, And Waist Hip Ratio With Covid 19 Outcomes And Severity In A Philippine Tertiary Hospital
  3. 29563
    “…Antifungal therapy was started and after seven days, the patient's clinical condition improved with resolution of his sepsis and DKA, and was successfully extubated. Patient was discharged to a rehabilitation facility. …”
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    ODP244 SGLT2 Inhibitor-Induced Euglycemic DKA and its Challenges
  4. 29564
    “…CONCLUSION: Distinct risk factors: birth weight, male sex, breathing problems at birth and PROM were significantly associated with the development of bacterial sepsis across South Asian community settings, supporting refined clinical discernment and targeted use of antimicrobials.…”
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    Risk factors for community-acquired bacterial infection among young infants in South Asia: a longitudinal cohort study with nested case–control analysis
  5. 29565
    “…METHODS: This was a monocentric, randomized, double-blind, placebo-controlled study that included patients with sepsis or acute respiratory distress syndrome. Patients received a specific combination of five amino acids or placebo mixed with enteral feeding for 21 days. …”
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    Effect of an enteral amino acid blend on muscle and gut functionality in critically ill patients: a proof-of-concept randomized controlled trial
  6. 29566
    “…Second complete remission status (CR2) was an independent risk factor for relapse-free survival (hazard ratio = 9.782, p = 0.001). The odds ratio for sepsis or bacteremia incidence was significantly greater in the PTCY group (9.524, p = 0.017). …”
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    Impact of posttransplant cyclophosphamide on the outcome of patients undergoing unrelated single-unit umbilical cord blood transplantation for pediatric acute leukemia
  7. 29567
    “…The negative outcomes were the need for positive pressure ventilation ([aOR] 1.831; 95% CI, (1.185,2.829); P = 0.019), ventilator support ([aOR] 1.843; 95% CI, (1.187,2.861); P = 0.011), and phototherapy ([aOR] 1.997; 95% CI, (1.378,2.895); P <  0.001), transient tachypnoea of the newborn ([aOR] 1.801; 95% CI, (1.261,2.571); P = 0.002), intraventricular haemorrhage ([aOR] 2.215; 95% CI, (1.159, 4.233); P = 0.027), sepsis ([aOR] 1.737; 95% CI, (1.086, 2.777); P = 0.007), and admission to neonatal intensive care ([aOR] 1.822; 95% CI, (1.275,2.604); P = 0.001). …”
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    A case-control study on the effects of incomplete, one, and more than one dexamethasone course on acute respiratory problems in preterm neonates born between 28(0) and 36(6) weeks of gestation
  8. 29568
    “…BACKGROUND: Acute lung injury (ALI) arises from sepsis or bacterial infection, which are life-threatening respiratory disorders that cause the leading cause of death worldwide. 5-Methoxyflavone, a methylated flavonoid, is gaining increased attention for its various health benefits. …”
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    5-Methoxyflavone alleviates LPS-mediated lung injury by promoting Nrf2-mediated the suppression of NOX4/TLR4 axis in bronchial epithelial cells and M1 polarization in macrophages
  9. 29569
    por Akinosoglou, Karolina, Kotsaki, Antigone, Gounaridi, Ioanna-Maria, Christaki, Eirini, Metallidis, Simeon, Adamis, Georgios, Fragkou, Archontoula, Fantoni, Massimo, Rapti, Aggeliki, Kalomenidis, Ioannis, Chrysos, Georgios, Boni, Gloria, Kainis, Ilias, Alexiou, Zoi, Castelli, Francesco, Serino, Francesco Saverio, Bakakos, Petros, Nicastri, Emanuele, Tzavara, Vassiliki, Safarika, Asimina, Ioannou, Sofia, Dagna, Lorenzo, Dimakou, Katerina, Tzatzagou, Glykeria, Chini, Maria, Bassetti, Matteo, Kotsis, Vasileios, Angheben, Andrea, Tsoukalas, George, Selmi, Carlo, Spiropoulou, Olga-Maria, Samarkos, Michael, Doumas, Michael, Damoraki, Georgia, Masgala, Aikaterini, Papanikolaou, Ilias, Argyraki, Aikaterini, Negri, Marcantonio, Leventogiannis, Konstantinos, Sympardi, Styliani, Gatselis, Nikolaos K., Petrakis, Vasileios, Netea, Mihai G., Panagopoulos, Periklis, Sakka, Vissaria, Milionis, Haralampos, Dalekos, George N., Giamarellos-Bourboulis, Evangelos J.
    Publicado 2022
    “…FUNDING: Hellenic Institute for the Study of Sepsis; Swedish Orphan Biovitrum AB.…”
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    Efficacy and safety of early soluble urokinase plasminogen receptor plasma-guided anakinra treatment of COVID-19 pneumonia: A subgroup analysis of the SAVE-MORE randomised trial
  10. 29570
    “…The independent associations between baseline procalcitonin and the risk of 50-day in-hospital mortality were maintained after adjusting for C-reactive protein and sepsis status at admission. CONCLUSION: Our data provide the first evidence of the usefulness of plasma procalcitonin at admission as a risk-stratifying biomarker for predicting 50-day in-hospital mortality among patients with community-acquired bloodstream infections. …”
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    Usefulness of procalcitonin at admission as a risk-stratifying biomarker for 50-day in-hospital mortality among patients with community-acquired bloodstream infection: an observational cohort study
  11. 29571
    “…In certain critical conditions, e.g. sepsis, acute respiratory failure (ARF) and trauma, the fibrinolytic response is reduced and may lead to widespread thrombosis and multi-organ failure. …”
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    Point-of-care diagnosis and monitoring of fibrinolysis resistance in the critically ill: results from a feasibility study
  12. 29572
    “…In accordance with the previous literature, we showed that Covid-19 associated coagulopathy is distinct from sepsis-induced DIC with prominent early endothelial involvement and fibrinolytic shut-down. …”
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    Coagulopathy is Initiated with Endothelial Dysfunction and Disrupted Fibrinolysis in Patients with COVID-19 Disease
  13. 29573
    por Delfino-Pereira, Polianna, Pires, Magda Carvalho, Gomes, Virginia Mara Reis, Nogueira, Matheus Carvalho Alves, Lima, Maria Clara Pontello Barbosa, Schwarzbold, Alexandre Vargas, Maurílio, Amanda de Oliveira, Scotton, Ana Luiza Bahia Alves, Costa, André Soares de Moura, Farace, Barbara Lopes, de Castro, Bruno Mateus, Cimini, Christiane Corrêa Rodrigues, Silveira, Daniel Vitório, Ponce, Daniela, Pereira, Elayne Crestani, Roesch, Eliane Würdig, Manenti, Euler Roberto Fernandes, Cenci, Evelin Paola de Almeida, dos Santos, Fernanda Costa, Anschau, Fernando, Aranha, Fernando Graça, Bartolazzi, Frederico, Nascimento, Guilherme Fagundes, Vianna, Heloisa Reniers, d'Arc Lyra Batista, Joanna, de Alvarenga, Joice Coutinho, Carvalho, Juliana da Silva Nogueira, Machado-Rugolo, Juliana, Ruschel, Karen Brasil, Menezes, Luanna Silva Monteiro, de Castro, Luís César, Nasi, Luiz Antônio, Floriani, Maiara Anschau, Souza, Maíra Dias, Souza-Silva, Maíra Viana Rego, Carneiro, Marcelo, Bicalho, Maria Aparecida Camargos, de Godoy, Mariana Frizzo, Guimarães-Júnior, Milton Henriques, Ziegelmann, Patricia Klarmann, Assaf, Pedro Ledic, Martelli, Petrônio José de Lima, Finger, Renan Goulart, Francisco, Saionara Cristina, Araújo, Silvia Ferreira, Oliveira, Talita Fischer, de Oliveira, Thainara Conceição, Lage, Thalita Martins, Muller, Vanessa, Ramires, Yuri Carlotto, Ferrari, Teresa Cristina de Abreu, Marcolino, Milena Soriano
    Publicado 2023
    “…Patients with hospital-manifested COVID-19 had a higher prevalence of cancer (19.2% vs 10.8%) and alcoholism (8.8% vs 2.8%) than patients with community-manifested COVID-19 and also had a higher rate of intensive care unit requirement (45.1% vs 35.2%), sepsis (23.8% vs 14.5%), and death (35.8% vs 22.5%) (P <0.05 for all). …”
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    Clinical characteristics and outcomes of hospital-manifested COVID-19 among Brazilians
  14. 29574
    “…BACKGROUND: Sepsis prognosis correlates with antibiotic adequacy at the early phase. …”
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    Impact of renal replacement therapy strategy on beta-lactam plasma concentrations: the BETAKIKI study—an ancillary study of a randomized controlled trial
  15. 29575
    “…Delayed Enteral Nutrition (EDEN), Hydroxymethylglutaryl-CoA reductase inhibition with simvastatin in Acute Lung Injury (ALI) to reduce pulmonary dysfunction (HARP-2), Statins for Acutely Injured Lungs from Sepsis (SAILS)) were used for analysis, with the VFD results summarised using mean, standard deviation (SD), median, interquartile range (25th and 75th percentiles) and minimum and maximum values. …”
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    Re-analysis of ventilator-free days (VFD) in acute respiratory distress syndrome (ARDS) studies
  16. 29576
    “…Analysis of intensive care unit (ICU) treatment (e.g. in case of sepsis or pneumonia) for both subgroups reveals a positive outcome in 10 of 15 patients (66.7%) with palliative AML treatment and in 15 of 18 patients (83.3%) receiving induction chemotherapy. …”
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    Impact of treatment intensity on infectious complications in patients with acute myeloid leukemia
  17. 29577
    “…Haemodynamic stability is the main tool to stratify patients for immediate surgery or not in the presence of sepsis/septic shock. Fifty-one surgical diseases were included in the different colour-code classes of priority. …”
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    The new timing in acute care surgery (new TACS) classification: a WSES Delphi consensus study
  18. 29578
    “…They are often associated with a high risk of sepsis and death. In recent years, antibiotic-resistant uropathogens ESKAPE (Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter baumannii, Pseudomonas aeruginosa, and Enterobacteriaceae) are increasingly encountered in UTIs. …”
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    Epidemiology of community origin of major multidrug-resistant ESKAPE uropathogens in a paediatric population in South-East Gabon
  19. 29579
    “…The PNAC group had higher respiratory distress syndrome, hemodynamically significant patent ductus arteriosus, necrotizing enterocolitis (NEC) with stage II or higher, surgically treated NEC, late-onset sepsis, metabolic bone disease, and extrauterine growth retardation (EUGR) compared to the non-PNAC group (P < 0.05 for all). …”
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    Analysis of risk factors for parenteral nutrition-associated cholestasis in preterm infants: a multicenter observational study
  20. 29580
    “…BACKGROUND: Vancomycin is commonly indicated to treat neonatal late-onset sepsis. At St. George’s Hospital, neonates with central-line access are administered vancomycin by continuous infusion. …”
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    P30 Evaluating vancomycin continuous infusion protocol compliance and gauging therapeutic target attainment in neonates
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