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  1. 29681
    “…We assessed systemic injury characteristics and the outcome of hospitalization with regard to sepsis, septic shock, pneumonia, or mortality. Results: EtOH with LI patients had significantly increased rates of pneumonia vs. the EtOH w/o LI group. …”
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    Circulating Extracellular Vesicles and Their miR “Barcode” Differentiate Alcohol Drinkers With Liver Injury and Those Without Liver Injury in Severe Trauma Patients
  2. 29682
    “…Compared to women delivering by ERCS, those who had a planned VBAC were significantly more likely to have uterine rupture (0.24%, n = 69 versus 0.04%, n = 17, adjusted odds ratio [aOR] 7.3, 95% confidence interval [CI] 3.9–13.9, p < 0.001), a blood transfusion (1.14%, n = 324 versus 0.50%, n = 226, aOR 2.3, 95% CI 1.9–2.8, p < 0.001), puerperal sepsis (0.27%, n = 76 versus 0.17%, n = 78, aOR 1.8, 95% CI 1.3–2.7, p = 0.002), and surgical injury (0.17% versus 0.09%, n = 40, aOR 3.0, 95% CI 1.8–4.8, p < 0.001) and experience adverse perinatal outcomes including perinatal death, admission to a neonatal unit, resuscitation requiring drugs and/or intubation, and an Apgar score < 7 at 5 minutes (7.99%, n = 2,049 versus 6.37%, n = 2,570, aOR 1.6, 95% CI 1.5–1.7, p < 0.001). …”
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    Planned mode of delivery after previous cesarean section and short-term maternal and perinatal outcomes: A population-based record linkage cohort study in Scotland
  3. 29683
    “…A study using administrative data found that GCA patients, when compared with a matched historical cohort, had increased rates of lower respiratory tract infections, UTI, and other serious infections, which are defined as pneumonias, upper urinary tract infections, and sepsis. The rate of infection is the highest in the first six months of treatment during the greatest glucocorticoid exposure. …”
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    29. Management of GCA and RA in patients with chronic suppurative lung disease
  4. 29684
    “…This is defined as an increase in the sequential organ failure assessment (SOFA) score of two or more, indicating sepsis and involvement of at least one organ. The SOFA score will be measured for the 14 days after enrolment from the baseline (the score at randomization). …”
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    Impact of Shenfu injection on a composite of organ dysfunction development in critically ill patients with coronavirus disease 2019 (COVID-19): A structured summary of a study protocol for a randomized controlled trial
  5. 29685
    “…Intraperitoneal injection of 30 mg/kg LPS was used to induce sepsis. Mice in the LPS + UFH group received subcutaneous injection of 8 U UFH 0.5 h before LPS injection. …”
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    Unfractionated heparin attenuates endothelial barrier dysfunction via the phosphatidylinositol-3 kinase/serine/threonine kinase/nuclear factor kappa-B pathway
  6. 29686
    “…Compared with infants receiving exclusive formula, those receiving the highest volume of human milk daily [≥50 mL/(kg · day)] had lower incidences of BPD [27.5% in ≥50 mL/(kg · day) vs 40.1% in 0 mL/(kg · day) human milk, P = 0.001)], moderate and severe BPD [8.9% in ≥50 mL/(kg · day) vs 16.1% in 0 mL/(kg · day), P = 0.004], necrotizing enterocolitis [NEC; 3.8% in ≥50 mL/(kg · day) vs 10.8% in 0 mL/(kg · day), P = 0.001], late-onset sepsis [LOS; 9.3% in ≥50 mL/(kg · day) vs 19.7% in 0 mL/(kg · day), P <0.01], and extrauterine growth retardation [EUGR; 38.5% in ≥50 mL/(kg · day) vs 57.6% in 0 mL/(kg · day), P <0.01)]. …”
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    Dose-dependent effect of human milk on Bronchopulmonary dysplasia in very low birth weight infants
  7. 29687
    “…Grade 3–4 toxicity was most commonly haematological: neutropenia in 46 (61%) of 75 patients, thrombocytopenia in 45 (60%), and anaemia in 26 (35%). 79 serious adverse events were recorded in 42 (56%) patients; four (5%) of those 79 were lethal due to sepsis caused by Gram-negative bacteria (treatment-related mortality 5%; 95% CI 0·07–9·93). …”
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    MATRix–RICE therapy and autologous haematopoietic stem-cell transplantation in diffuse large B-cell lymphoma with secondary CNS involvement (MARIETTA): an international, single-arm, phase 2 trial
  8. 29688
    “…MAIN OUTCOMES AND MEASURES: Survival to discharge and major morbidity (ie, bronchopulmonary dysplasia, grades III-IV intraventricular hemorrhage, white matter injury, stage II-III necrotizing enterocolitis, sepsis, or severe retinopathy of prematurity) were measured. …”
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    Mortality and Morbidity of Infants Born Extremely Preterm at Tertiary Medical Centers in China From 2010 to 2019
  9. 29689
    “…In addition, 789 hospitalizations had a secondary diagnosis of COVID-19, of which 446 (56.5%) had a principal diagnosis consistent with severe clinical manifestation of COVID-19 (e.g., sepsis or respiratory failure). Compared with the cohort that had a principal diagnosis of COVID-19, those with a secondary diagnosis had a more than 2-fold higher in-hospital mortality rate (13.2% vs 28.0%, P<0.001). …”
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    Accuracy of Computable Phenotyping Approaches for SARS-CoV-2 Infection and COVID-19 Hospitalizations from the Electronic Health Record
  10. 29690
    “…METHODS: We analysed data from the African Neonatal Sepsis Trial conducted in five sites in the Democratic Republic of the Congo, Kenya and Nigeria. …”
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    Clinical signs of possible serious infection and associated mortality among young infants presenting at first-level health facilities
  11. 29691
    “…A trained examiner per centre will conduct examinations at baseline, at 5–5.5 months (3 months after basic management), 8.5 and 12 months, assessing the child’s CCI caries risk and oral-health behaviour, visually staging and assessing caries-lesions severity and activity without air-drying (ICDAS-merged Epi); fillings/sealants; missing/dental-sepsis teeth, and tooth symptoms, synthetizing together with parent and external-trained dental practitioner (DP) the patient- and tooth-surface level diagnoses and personalised care plan. …”
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    CariesCare International adapted for the pandemic in children: Caries OUT multicentre single-group interventional study protocol
  12. 29692
    “…Patients treated with standard prophylaxis had less CRNMB (1.11%), but this was not statistically significant in a multivariate analysis that included other confounding factors such as age, sex, ethnicity, BMI, comorbidity, HASBLED bleeding risk, and sepsis induced coagulopathy score (SICS). The mortality rate was 12.6% in the whole cohort (7.22%, 21.21% and 26% in prophylactic, escalated prophylactic, and therapeutic dosage, respectively). …”
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    The Role of D-Dimer for Optimal Thromboprophylaxis Strategy in Patients with COVID-19
  13. 29693
    “…Initial studies on patients in Wuhan, China showed anticoagulant therapy mainly with low molecular weight heparin was reported to be associated with better prognosis in severe COVID‐19 patients meeting sepsis‐induced coagulopathy criteria or with markedly elevated D‐dimer. …”
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    Outcomes in COVID-19 Patients on Treatment Dose Anti-Coagulation Compared to Prophylactic Dose Anti-Coagulation
  14. 29694
    “…Life-threatening thrombocytopenia occurred in an auranofin recipient; apparent intra-abdominal sepsis leading to death occurred in another auranofin recipient and was classified as a suspected unexpected serious adverse reaction. …”
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    Adjunctive host-directed therapies for pulmonary tuberculosis: a prospective, open-label, phase 2, randomised controlled trial
  15. 29695
    por Tripathy, Swagata, Rao, P. Bhaskar
    Publicado 2021
    “…Severe hypoxemia warranting cessation of NIV and intubation, non-acceptance of NIV and proven sepsis. Technical difficulty for epidural catheterization, coagulation abnormalities, low respiratory drive and EOL orders. …”
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    Epidural morphine in COVID ARDS patients with high respiratory drive: a structured summary of a study protocol for a randomised controlled trial
  16. 29696
    por Paredes, Igor, Castaño Leon, Ana Maria, Lagares, Alfonso, Jimenez Roldan, Luis, Perez-Nuñez, Angel, González-Leon, Pedro, Delgado-Fernandez, Juan, Eiriz, Carla, García-Pérez, Daniel, Moreno-Gomez, Luis Miguel, Esteban-Sinovas, Olga, Delgado-López, Pedro, Martín-Alonso, Javier, Kaen, Ariel, Tirado-Caballero, Jorge, Ordóñez Carmona, Marta, Arteaga Romero, Francisco, Gonzalez Pombo, Marta, Alén, José F, Gil-Simoes, Ricardo, Torres, Cristina V, Navas Garcia, Marta, Blasco, Guillermo, Frade-Porto, Natalia, González-Tarno, Patricia, Martin Segura, Adrian, Gelabert-Gonzalez, Miguel, Menendez Cortezon, Beatriz, Rodriguez Botana, Brais, Pérez-Alfayate, Rebeca, Fernandez Garcia, Carla, Ferrandez Pujante, Borja, Vargas-Jiménez, Andres, Cotúa, Carlos, de la Lama, Adolfo, Calero, Lourdes, Ruiz-Juretschke, Fernando, Garcia Leal, Roberto, Valera Mele, Marc, Casitas Hernando, Vicente, Rivero Martín, Belén, Orduna, Javier, Casado Pellejero, Juan, Fustero De Miguel, David, Diaz-Molina, Jorge, Moles Herbera, Jesus, Castello Ruiz, Maria Jose, Gomar Alba, Mario, Garcia Perez, Fernando, Hernandez Garcia, Borja Jesus, Villaseñor Ledezma, Javier, Otero Rodríguez, Álvaro, Ailagas, Juan José, Goncalves-Estella, Jesús, Sousa Casasnovas, Pablo, Pascual Argente, Daniel, Ruiz Martín, Laura, Roa Montes de Oca, Juan Carlos, Arandia Guzmán, Daniel, García Martín, Andoni, Torres Carretero, Luis, Garrido Ruíz, Patricia Alejandra, Calvo, Marta, Miranda-Lloret, Pablo, Rodriguez-Cadarso Suarez-Vence, Miguel, Anotn Oltra, Joan, Roca Barber, Amparo, Quiroz Tejada, Arnold, Carbayo Lozano, Guillermo, Bermudez Vilar, Garazi, Paternain Martin, Clara, Dela FuenteVilla, Pablo, Fidalgo De la Rosa, Marina, Sistiaga García, Íñigo L, Zabalo San Juan, Gorka
    Publicado 2021
    “…For SARS-CoV-2 postoperative infection, screening swab test <72 hours preoperatively (OR 0.76), community COVID-19 incidence (cases/10(5) people/week) (OR 1.011), preoperative cognitive impairment (OR 2.784), postoperative sepsis (OR 3.807) and an absence of postoperative complications (OR 0.188) were independently associated. …”
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    Impact of the first wave of the SARS-CoV-2 pandemic on the outcome of neurosurgical patients: a nationwide study in Spain
  17. 29697
    “…For example, the random forest model trained with 135 input features had the highest AUROC values for predicting acute kidney injury (0.82; 95% CI, 0.82-0.83); cardiovascular complications (0.81; 95% CI, 0.81-0.82); neurological complications, including delirium (0.87; 95% CI, 0.87-0.88); prolonged intensive care unit stay (0.89; 95% CI, 0.88-0.89); prolonged mechanical ventilation (0.91; 95% CI, 0.90-0.91); sepsis (0.86; 95% CI, 0.85-0.87); venous thromboembolism (0.82; 95% CI, 0.81-0.83); wound complications (0.78; 95% CI, 0.78-0.79); 30-day mortality (0.84; 95% CI, 0.82-0.86); and 90-day mortality (0.84; 95% CI, 0.82-0.85), with accuracy similar to surgeons’ predictions. …”
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    Performance of a Machine Learning Algorithm Using Electronic Health Record Data to Predict Postoperative Complications and Report on a Mobile Platform
  18. 29698
    “…The indication of enrofloxacin powder (used for aquaculture) is the treatment of hemorrhage and sepsis in aquaculture animals such as fish and eel. …”
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    恩诺沙星粉中未知添加物的确证
  19. 29699
    “…One patient recovered from sepsis (serious AE). Two non-responders developed high ADA titers; fewer patients had trough concentrations (C(min)) below the quantitation limit (BQL), and the median C(min) was higher (1.03 µg/mL vs. …”
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    A multicentre, efficacy and safety study of methotrexate to increase response rates in patients with uncontrolled gout receiving pegloticase (MIRROR): 12-month efficacy, safety, immunogenicity, and pharmacokinetic findings during long-term extension of an open-label study
  20. 29700
    “…Nous nous proposons dans cette étude d’évaluer la rentabilité pronostique des systèmes de notation communément utilisés dans les pneumonies aiguës communautaires (PAC), à savoir le score CURB65 et le score de fine, ainsi que le score d’alerte précoce NEWS2 utilisé dans le cadre de sepsis. MÉTHODES: Il s’agit d’une étude rétrospective menée sur des patients âgés de plus de 18 ans, ayant une pneumonie à SARS-COV-2 confirmée par Rt-PCR et/ou scanner thoracique. …”
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    Pneumonie à SARS-COV-2 : rentabilité pronostique des scores de sévérité
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