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  1. 29721
    “…Following Cox proportional hazards models, no significant differences were found for these outcomes. Sepsis, hypothyroidism, attention deficit hyperactivity disorder, autism spectrum disorders, mental retardation, cerebral palsy, and epilepsy were diagnosed in a maximum of three PGT children. …”
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    Preimplantation genetic testing and child health: a national register-based study
  2. 29722
    por Kirkpatrick, Andrew W., Coccolini, Federico, Tolonen, Matti, Minor, Samuel, Catena, Fausto, Gois, Emanuel, Doig, Christopher J., Hill, Michael D., Ansaloni, Luca, Chiarugi, Massimo, Tartaglia, Dario, Ioannidis, Orestis, Sugrue, Michael, Colak, Elif, Hameed, S. Morad, Lampela, Hanna, Agnoletti, Vanni, McKee, Jessica L., Garraway, Naisan, Sartelli, Massimo, Ball, Chad G., Parry, Neil G., Voght, Kelly, Julien, Lisa, Kroeker, Jenna, Roberts, Derek J., Faris, Peter, Tiruta, Corina, Moore, Ernest E., Ammons, Lee Anne, Anestiadou, Elissavet, Bendinelli, Cino, Bouliaris, Konstantinos, Carroll, Rosemarry, Ceresoli, Marco, Favi, Francesco, Gurrado, Angela, Rezende-Neto, Joao, Isik, Arda, Cremonini, Camilla, Strambi, Silivia, Koukoulis, Georgios, Testini, Mario, Trpcic, Sandy, Pasculli, Alessandro, Picariello, Erika, Abu-Zidan, Fikri, Adeyeye, Ademola, Augustin, Goran, Alconchel, Felipe, Altinel, Yuksel, Hernandez Amin, Luz Adriana, Aranda-Narváez, José Manuel, Baraket, Oussama, Biffl, Walter L., Baiocchi, Gian Luca, Bonavina, Luigi, Brisinda, Giuseppe, Cardinali, Luca, Celotti, Andrea, Chaouch, Mohamed, Chiarello, Maria, Costa, Gianluca, de’Angelis, Nicola, De Manzini, Nicolo, Delibegovic, Samir, Di Saverio, Salomone, De Simone, Belinda, Dubuisson, Vincent, Fransvea, Pietro, Garulli, Gianluca, Giordano, Alessio, Gomes, Carlos, Hayati, Firdaus, Huang, Jinjian, Ibrahim, Aini Fahriza, Huei, Tan Jih, Jailani, Ruhi Fadzlyana, Khan, Mansoor, Luna, Alfonso Palmieri, Malbrain, Manu L. N. G., Marwah, Sanjay, McBeth, Paul, Mihailescu, Andrei, Morello, Alessia, Mulita, Francesk, Murzi, Valentina, Mohammad, Ahmad Tarmizi, Parmar, Simran, Pak, Ajay, Wong, Michael Pak-Kai, Pantalone, Desire, Podda, Mauro, Puccioni, Caterina, Rasa, Kemal, Ren, Jianan, Roscio, Francesco, Gonzalez-Sanchez, Antonio, Sganga, Gabriele, Scheiterle, Maximilian, Slavchev, Mihail, Smirnov, Dmitry, Tosi, Lorenzo, Trivedi, Anand, Vega, Jaime Andres Gonzalez, Waledziak, Maciej, Xenaki, Sofia, Winter, Desmond, Wu, Xiuwen, Zakaria, Andee Dzulkarnean, Zakaria, Zaidi
    Publicado 2023
    “…BACKGROUND: Severe complicated intra-abdominal sepsis (SCIAS) has an increasing incidence with mortality rates over 80% in some settings. …”
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    The unrestricted global effort to complete the COOL trial
  3. 29723
    “…TOPICS: Sickle cell anemia, vaso-occlusive pain crisis, acute chest syndrome, hypoxia, pneumonia, sepsis.…”
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    Acute Chest Syndrome
  4. 29724
    “…Fowler, MD, MHS, Amphliphi Biosciences, Integrated Biotherapeutics; C3J, Armata, Valanbio; Akagera, Aridis, Roche, Astra Zeneca: Advisor/Consultant|Genentech, Regeneron, Deep Blue, Basilea, Janssen;: Grant/Research Support|Infectious Diseases Society of America: Honoraria|MedImmune, Allergan, Pfizer, Advanced Liquid Logics, Theravance, Novartis, Merck; Medical Biosurfaces; Locus; Affinergy; Contrafect; Karius;: Grant/Research Support|Novartis, Debiopharm, Genentech, Achaogen, Affinium, Medicines Co., MedImmune, Bayer, Basilea, Affinergy, Janssen, Contrafect, Regeneron, Destiny,: Advisor/Consultant|Sepsis diagnostic: Patent pending|UpToDate: Royalties|Valanbio and ArcBio: Stock Options Mark E. …”
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    2785. Characterization of Methicillin-resistant Staphylococcus aureus Bloodstream Isolates Recovered from Patients Enrolled in a Randomized, Double-blind, Multi-center Study to Establish the Efficacy and Safety of Ceftobiprole for Treatment of Bacteremia, Including Infective Endocarditis
  5. 29725
    “…Fowler, MD, MHS, Amphliphi Biosciences, Integrated Biotherapeutics; C3J, Armata, Valanbio; Akagera, Aridis, Roche, Astra Zeneca: Advisor/Consultant|Genentech, Regeneron, Deep Blue, Basilea, Janssen;: Grant/Research Support|Infectious Diseases Society of America: Honoraria|MedImmune, Allergan, Pfizer, Advanced Liquid Logics, Theravance, Novartis, Merck; Medical Biosurfaces; Locus; Affinergy; Contrafect; Karius;: Grant/Research Support|Novartis, Debiopharm, Genentech, Achaogen, Affinium, Medicines Co., MedImmune, Bayer, Basilea, Affinergy, Janssen, Contrafect, Regeneron, Destiny,: Advisor/Consultant|Sepsis diagnostic: Patent pending|UpToDate: Royalties|Valanbio and ArcBio: Stock Options David van Duin, MD, PhD, Entasis: Advisor/Consultant|Merck: Advisor/Consultant|Merck: Grant/Research Support|Pfizer: Advisor/Consultant|Pfizer: Honoraria|Qpex: Advisor/Consultant|Roche: Advisor/Consultant|Shionogi: Advisor/Consultant|Shionogi: Grant/Research Support|Union: Advisor/Consultant|Utility: Advisor/Consultant…”
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    1029. Increased Mortality in Hospital-Onset Carbapenem-Resistant Enterobacterales Bloodstream Infections
  6. 29726
    “…Fowler, MD, MHS, Amphliphi Biosciences, Integrated Biotherapeutics; C3J, Armata, Valanbio; Akagera, Aridis, Roche, Astra Zeneca: Advisor/Consultant|Genentech, Regeneron, Deep Blue, Basilea, Janssen;: Grant/Research Support|Infectious Diseases Society of America: Honoraria|MedImmune, Allergan, Pfizer, Advanced Liquid Logics, Theravance, Novartis, Merck; Medical Biosurfaces; Locus; Affinergy; Contrafect; Karius;: Grant/Research Support|Novartis, Debiopharm, Genentech, Achaogen, Affinium, Medicines Co., MedImmune, Bayer, Basilea, Affinergy, Janssen, Contrafect, Regeneron, Destiny,: Advisor/Consultant|Sepsis diagnostic: Patent pending|UpToDate: Royalties|Valanbio and ArcBio: Stock Options…”
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    963. External Validation of the 2023 Duke - International Society for Cardiovascular Infectious Diseases (ISCVID) Diagnostic Criteria for Infective Endocarditis (IE)
  7. 29727
    “…BACKGROUND: Severe manifestations of human parechovirus (HPeV) infection, including meningoencephalitis and sepsis, can occur in neonates and young infants. Death has rarely been reported. …”
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    1747. Clinical Spectrum of a Large Multi-State U.S. Cohort of Parechovirus Infection in Neonates and Young Infants
  8. 29728
    “…CT and CZA patients were matched 1:1 within each study site by the presence/absence of septic shock/severe sepsis, infection site, and time to treatment initiation. …”
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    1109. A multicenter, observational study to compare the effectiveness of Ceftazidime-Avibactam versus Ceftolozane-Tazobactam for multidrug-resistant Pseudomonas aeruginosa infections in the United States (CACTUS)
  9. 29729
    “…At the last follow-up visit, the platelet count had increased to 20–50 × 10(9) per L in one patient, 50–100 × 10(9) per L in five patients, and more than 100 × 10(9) per L in two patients, which resulted in independence from platelet transfusions and absence of severe bleeding events. 27 serious adverse events in six patients occurred after gene therapy, 23 (85%) of which were infectious (pyrexia [five events in three patients], device-related infections, including one case of sepsis [four events in three patients], and gastroenteritis, including one case due to rotavirus [three events in two patients]); these occurred mainly in the first 6 months of follow-up. …”
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    Lentiviral haemopoietic stem/progenitor cell gene therapy for treatment of Wiskott-Aldrich syndrome: interim results of a non-randomised, open-label, phase 1/2 clinical study
  10. 29730
    “…The endogenous tryptic peptides of Alzheimer’s were compared to normals, multiple sclerosis, ovarian cancer, breast cancer, female normal, sepsis, ICU Control, heart attack, along with their institution-matched controls, and normal samples collected directly onto ice. …”
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    The plasma peptides of Alzheimer’s disease
  11. 29731
    “…According to the International Society on Thrombosis and Hemostasis’ criteria (ISTH criteria) 40 patients (8.9%) had overt-DIC, sepsis induced coagulopathy (SIC) was present in 28 patients (6.3%), and high risk for bleeding by IMPROVE score ≥7 points was found in 5 patients (1.1%). …”
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    Low Rate of Thrombosis in Mexican Patients with COVID-19 Infection. a Benefit of Higher Doses Anticoagulants or a Sub Diagnosis?
  12. 29732
    “…Of the NICU admissions, 61.5% were because of hypoglycemia or an evaluation for sepsis. Other reasons for admission included prematurity, hypothermia, and transient tachypnea of the newborn. …”
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    COVID-19 vaccination in pregnancy: early experience from a single institution
  13. 29733
    “…Almost one-third of the isolates were resistant to both first-line drugs recommended for the management of neonatal sepsis (ampicillin and gentamicin). Overall, 38 deaths occurred among neonates with SBI (possible and culture-confirmed SBI together). …”
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    Severe bacterial neonatal infections in Madagascar, Senegal, and Cambodia: A multicentric community-based cohort study
  14. 29734
    “…La contribution de cette stratégie thérapeutique pour la prise en charge des infections reste toutefois controversée, malgré quelques études en faveur de leur utilisation, notamment dans le contexte de paralysie immunitaire au décours d’un sepsis sévère [2], [3], ou dans les situations d’épuisement immunitaire au cours des infections virales chroniques [4], [5]. …”
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    Impact des inhibiteurs de checkpoints immunitaires au cours de la COVID-19 chez les patients atteints de mélanome
  15. 29735
    “…Overall, 217 (33%) pts had severe disease, COVID-19 complications were detected in 458 (70%) pts, the most common were pneumonia in 425 (93%) pts, respiratory failure in 252 (55%) pts, multiple organ failure in 56 (12%) pts, cytokine storm in 52 (11%) pts, ARDS in 47 (10%) pts, and sepsis in 44 (10%) pts. The rate of ICU admission was 23% (145 pts) with high mortality in this group of pts (77%), 111 (17%) pts required mechanical ventilation, among them only 5 (4.5%) pts survived. …”
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    Final Results of CHRONOS19 Observational Study in Patients with Hematologic Disease and COVID-19 in Russia
  16. 29736
    por Amjad, Qurat Ul Ain, Ellis, Spencer
    Publicado 2021
    “…Her pregnancy was subsequently complicated by pre-eclampsia and post-partum sepsis. Two years later she sought advice to plan her second pregnancy, raising important questions as to whether the same treatment strategy should be followed or if alternative approaches should be considered, given the history of pre-eclampsia and its association with APS. …”
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    O22 Pregnancy planning in non-criteria antiphospholipid syndrome
  17. 29737
    “…All patients were asymptomatic for graft infection - no abdominal pain, fever of unknown origin, sepsis, or leukocytosis - at the time of imaging and for ≥ 2 mo after each PET/CT. …”
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    Appearance of aseptic vascular grafts after endovascular aortic repair on [(18)F]fluorodeoxyglucose positron emission tomography/computed tomography
  18. 29738
    “…Among the complications, besides the respiratory worsening, renal failure, liver failure and the state of sepsis were most frequently found; less frequent complications were lesions induced by ventilation with a barotrauma mechanism, ischemic heart disease, the appearance of central neurological events of sensory alterations, meningo - encephalitis and cerebral hemorrhage, and peripheral neurological events with polyneuro - myopathies. …”
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    Intensive care for seriously ill patients affected by novel coronavirus sars - CoV – 2: Experience of the Crema Hospital, Italy
  19. 29739
    “…INTERVENTION AND COMPARATOR: The intervention consists in a single oral dose of 500.000 IU of commercially available cholecalciferol soft gel capsules (5 capsules of 100.000 IU) or matching placebo MAIN OUTCOMES: The primary outcome for the first stage is the change in the respiratory Sepsis-related Organ Failure Assessment (SOFAr) score between pre-treatment value and the worst value recorded during the first 7 seven days of hospitalization, the death or discharge, whichever occurs first. …”
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    High-dose vitamin D versus placebo to prevent complications in COVID-19 patients: A structured summary of a study protocol for a randomised controlled trial (CARED-TRIAL)
  20. 29740
    “…Patients with documented significant liver disease/dysfunction (AST/ALT > 240), myopathy and rhabdomyolysis (CPK > 5x normal), allergy or intolerance to statins, allergy or intolerance to aspirin, patients taking medications with significant interaction with statins, prior statin use (within 30 days), prior aspirin use (within 30 days), history of active GI bleeding in past three months, coagulopathy, thrombocytopenia (platelet count < 100000/ dl), pregnancy, active breastfeeding, patient unable to take oral or nasogastric medications, patients in altered mental status, shock, acute renal failure, acute coronary syndrome, sepsis and ARDS at presentation will be excluded. …”
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    A randomized open-label trial to evaluate the efficacy and safety of triple therapy with aspirin, atorvastatin, and nicorandil in hospitalised patients with SARS Cov-2 infection: A structured summary of a study protocol for a randomized controlled trial
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