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20281por Bray, Jonathan James Hyett, Lloyd, Elin Fflur, Adenwalla, Firdaus, Kelly, Sarah, Wareham, Kathie, Halcox, Julian P J“…CONCLUSIONS: We have demonstrated that the AliveCor system is a feasible, cost-effective, time-efficient and potentially safer alternative to serial 12-lead ECGs for community monitoring and diagnosis of AF.…”
Publicado 2021
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20282por Manenti, Lucio, Maggiore, Umberto, Fiaccadori, Enrico, Meschi, Tiziana, Antoni, Anna Degli, Nouvenne, Antonio, Ticinesi, Andrea, Cerundolo, Nicoletta, Prati, Beatrice, Delsante, Marco, Gandoflini, Ilaria, Donghi, Lorenzo, Gentile, Micaela, Farina, Maria Teresa, Oliva, Vincenzo, Zambrano, Cristina, Regolisti, Giuseppe, Palmisano, Alessandra, Caminiti, Caterina, Cocchi, Enrico, Ferrari, Carlo, Riella, Leonardo V., Cravedi, Paolo, Peruzzi, Licia“…METHODS: This retrospective study included 71 consecutive COVID-19 patients (hospitalized with pneumonia on CT scan or outpatients) who received colchicine and compared with 70 control patients who did not receive colchicine in two serial time periods at the same institution. We used inverse probability of treatment propensity-score weighting to examine differences in mortality, clinical improvement (using a 7-point ordinary scale), and inflammatory markers between the two groups. …”
Publicado 2021
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20283por Karamitopoulou, Eva, Esposito, Irene, Zlobec, Inti, Insilla, Andrea Cacciato, Wartenberg, Martin, Schaeffer, David F., Kalloger, Steve, La Rosa, Stefano, Sempoux, Christine, Ramos Centeno, Irene, Lohneis, Philipp“…We performed a multicenter interobserver study to test various budding assessment methods for their reproducibility. Two serial sections of 50 resected, treatment-naïve PDACs were stained for Hematoxylin and Eosin (H&E) and pancytokeratin. …”
Publicado 2020
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20284por Nestelberger, Thomas, Lopez-Ayala, Pedro, Boeddinghaus, Jasper, Strebel, Ivo, Rubini Gimenez, Maria, Huber, Iris, Wildi, Karin, Wussler, Desiree, Koechlin, Luca, Prepoudis, Alexandra, Gualandro, Danielle M., Puelacher, Christian, Glarner, Noemi, Haaf, Philip, Frey, Simon, Bakula, Adam, Wick, Rupprecht, Miró, Òscar, Martin-Sanchez, F. Javier, Kawecki, Damian, Keller, Dagmar, Twerenbold, Raphael, Mueller, Christian“…The final diagnoses of T2MI and T1MI were centrally adjudicated by two independent cardiologists using all information including cardiac imaging and serial measurements of hs-cTnT/I according to the fourth universal definition of MI. …”
Publicado 2021
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20285por Bouwer, N. I., Steenbruggen, T. G., van Rosmalen, J., Rier, H. N., Kitzen, J. J. E. M., van Bekkum, M. L., Tije, A. J. Ten, de Jong, P. C., Drooger, J. C., Holterhues, C., Smorenburg, C. H., Kofflard, M. J. M., Boersma, E., Sonke, G. S., Levin, M.-D., Jager, A.“…Despite continuing trastuzumab, LVEF decline was reversible in 56% of patients with non-severe cardiotoxicity and in 33% with severe cardiotoxicity. CONCLUSIONS: Serial cardiac monitoring can be safely omitted in non-smoking patients with baseline LVEF > 60% and without cardiotoxicity during prior neoadjuvant/adjuvant treatment. …”
Publicado 2021
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20286por Frankenstein, Ziv, Uraoka, Naohiro, Aypar, Umut, Aryeequaye, Ruth, Rao, Mamta, Hameed, Meera, Zhang, Yanming, Yagi, Yukako“…Confocal WSI has the ability to perform serial optical sections with specimen imaging, which is critical for 3D tissue reconstruction for volumetric spatial analysis. …”
Publicado 2021
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20287por Hong, Ji Young, Kim, Ahreum, Park, So Yeong, Cho, Sang-Nae, Dockrell, Hazel M., Hur, Yun-Gyoung“…METHODS: A total of 758 contacts were investigated for M. tb infection, and 43 contacts with latent TB infection (LTBI) and 25 active TB patients were enrolled based on serial screening with QuantiFERON-TB Gold In-Tube tests followed by clinical examinations. …”
Publicado 2021
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20288“…We also replicate an established experimental effect in the creativity literature (i.e., the serial order effect) and show that semantic distance correlates with other creativity measures, demonstrating convergent validity. …”
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20289por Schmidt, Frank P, Herzog, Johannes, Schnorbus, Boris, Ostad, Mir Abolfazl, Lasetzki, Larissa, Hahad, Omar, Schäfers, Gianna, Gori, Tommaso, Sørensen, Mette, Daiber, Andreas, Münzel, Thomas“…Sleep quality was impaired after noise exposure in both noise scenario nights (P < 0.001). Serial echocardiographic assessment demonstrated an increase in the E/E′ ratio, a measure of diastolic function, within the three exposure nights, with a ratio of 6.83 ± 2.26 for the control night, 7.21 ± 2.33 for Noise60 and 7.83 ± 3.07 for Noise120 (P = 0.043). …”
Publicado 2020
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20290“…The identity of the iTIME.219 cells was confirmed both phenotypically (specific antigen expression) and genetically (short tandem repeat analysis), and cell stability was maintained following repeated serial passage. These results suggest the potential utility of the iTime.219 cells in future studies of the KSHV replication in endothelial cells, properties of virus generated from this biologically relevant cell type and mechanisms underlying KSHV tropism and pathogenesis.…”
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20291“…Clinical evaluation included assessing clinical sensitivity, specificity, cross-reactivity, positive predictive value (PPV), negative predictive value (NPV), and serial sampling from the same patient. The Elecsys anti-SARS-CoV-2 S assay exhibited its highest sensitivity (84.0%) at 15 to 30 days post-PCR positivity and exhibited no cross-reactivity, a specificity and PPV of 100%, and an NPV between 98.3% and 99.8% at ≥14 days post-PCR positivity, depending on the seroprevalence estimate. …”
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20292por Cordeiro, Maria Lúcia da Silva, Ribeiro, Ana Raquel Carneiro, de Melo, Luciana Fentanes Moura, da Silva, Lucas Felipe, Fidelis, Gabriel Pereira, Silva, Larissa Marina Pereira, Caland, Ricardo Basílio de Oliveira, Cadavid, Cesar Orlando Muñoz, Aragão, Cícero Flavio Soares, Zucolotto, Silvana Maria, Oliveira, Riva de Paula, dos Santos, Deborah Yara Alves Cursino, Rocha, Hugo Alexandre Oliveira, Scortecci, Katia Castanho“…Six extracts were obtained from fresh leaves using a serial extraction (nonpolar to polar solvents). These extracts were first evaluated with the presence of phytochemical compounds using the methods thin layer chromatography (TLC), ultrahigh performance liquid chromatography (UHPLC-DAD), and high performance liquid chromatography, both with diode array detection (HPLC-DAD). …”
Publicado 2021
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20293por Mazzilli, Sara, Oliani, Francesco, Restivo, Andrea, Giuliani, Ruggero, Tavoschi, Lara, Ranieri, Roberto“…DISCUSSION: Our study showed that ag-RDT is a promising and useful component of serial testing strategies in prison settings to perform SARS-CoV2 screening at admission based to its high PPV, ease of use, lower costs and resource needs.…”
Publicado 2021
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20294por Pham, Nhu-An, Radulovich, Nikolina, Ibrahimov, Emin, Martins-Filho, Sebastiao N., Li, Quan, Pintilie, Melania, Weiss, Jessica, Raghavan, Vibha, Cabanero, Michael, Denroche, Robert E., Wilson, Julie M., Metran-Nascente, Cristiane, Borgida, Ayelet, Hutchinson, Shawn, Dodd, Anna, Begora, Michael, Chadwick, Dianne, Serra, Stefano, Knox, Jennifer J., Gallinger, Steven, Hedley, David W., Muthuswamy, Lakshmi, Tsao, Ming-Sound“…Subsets of PDAC PDX models showed global copy number variants and gene expression profiles that were retained with serial passaging, and they showed a spectrum of somatic mutations represented in patient tumors. …”
Publicado 2021
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20295por Machowski, Edith E., Letutu, Matebogo, Lebina, Limakatso, Waja, Ziyaad, Msandiwa, Reginah, Milovanovic, Minja, Gordhan, Bhavna G., Otwombe, Kennedy, Friedrich, Sven O., Chaisson, Richard, Diacon, Andreas H., Kana, Bavesh, Martinson, Neil“…Sputum bacillary load, as a marker of treatment response, was determined serially by: smear microscopy, Xpert MTB/RIF, liquid culture, and colony counts on agar medium. …”
Publicado 2021
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20296por Dundon, William G., Settypalli, Tirumala B.K., Spiegel, Katharina, Steinrigl, Adi, Revilla-Fernández, Sandra, Schmoll, Friedrich, Naletoski, Ivancho, Lamien, Charles E., Cattoli, Giovanni“…The limit of detection was calculated for each assay using serial dilutions of a defined clinical sample. The performances of the assays were compared using a panel of 178 clinical samples and their analytical specificity assessed against a panel of human betacoronaviruses. …”
Publicado 2021
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20297por Donson, Andrew, Ritzmann, Timothy, Willard, Nicholas, Griesinger, Andrea, Amani, Vladimir, Harris, Faith, Grimaldo, Enrique, Sanford, Bridget, Riemondy, Kent, Hankinson, Todd, Grundy, Richard, Foreman, Nicholas“…In the present longitudinal study we examine changes in neoplastic cell heterogeneity in serial presentations of PFA EPN using deconvolution (Cibersort) of bulk RNAseq data. …”
Publicado 2021
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20298por Yamamoto, Hiroyuki, Shinke, Toshiro, Otake, Hiromasa, Kawamori, Hiroyuki, Toba, Takayoshi, Kuroda, Masaru, Hirota, Yushi, Sakaguchi, Kazuhiko, Ogawa, Wataru, Hirata, Ken‐ichi“…At 9 months after enrollment, culprit and non‐culprit (mild‐to‐moderate stenosis without ischemia) lesions were serially assessed by angiography. Cardiovascular events (CVE) consisting of cardiovascular death, non‐fatal myocardial infarction or ischemia‐driven revascularization during 2‐year follow up, rapid progression in non‐culprit lesions (defined as ≥10% luminal narrowing progression in lesions with stenosis ≥50%, ≥30% luminal narrowing progression in non‐culprit lesions with stenosis <50% or normal segment, or progression to total occlusion) were evaluated. …”
Publicado 2020
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20299por Kim, Kyuwon, Jo, Kyung-Wook, Shim, Tae Sun, Park, Jin Hwa, Hwang, Sung Wook, Park, Sang Hyoung, Yang, Dong-Hoon, Byeon, Jeong-Sik, Myung, Seung-Jae, Yang, Suk-Kyun, Ye, Byong Duk“…Among IBD patients treated with vedolizumab and/or ustekinumab, a total of 91 patients who had negative baseline interferon-gamma release assay (IGRA) results, assessed by QuantiFERON(®)-TB Gold In-tube or QuantiFERON(®)-TB Gold Plus, were enrolled. Serial LTBI test results after starting non-TNF inhibitor therapy were collected, and patients' clinical characteristics were analyzed. …”
Publicado 2021
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20300por Hwang, Sejung, Lee, Dae Young, Cho, Joo-Youn, Chung, Jae-Yong, Jang, In-Jin, Yu, Kyung-Sang, Lee, SeungHwan“…Healthy male subjects were randomized to DA-8031 or placebo at a 4:1 ratio in each dose group of 10 subjects by oral administration once daily for 7 consecutive days. Serial blood and urine samples were collected for the pharmacokinetic evaluation, and the pharmacokinetic-related genes were analyzed by DMET(TM) plus. …”
Publicado 2021
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