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20501por Parchwani, Deepak, Sonagra, Amit D, Dholariya, Sagar, Motiani, Anita, Singh, Ragini“…CONCLUSION: Hepatic dysfunction in SARS-CoV-2 infection could be the result of individual drugs or due to drug-drug interactions and may be in a subset of patients with a genetic propensity. Thus, serial estimation of hepatic indices in hospitalized SARS-CoV-2 patients should be done to make timely corrective actions for iatrogenic causes to avoid clinical deterioration. …”
Publicado 2023
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20502por de Capretz, Pontus Olsson, Björkelund, Anders, Björk, Jonas, Ohlsson, Mattias, Mokhtari, Arash, Nyström, Axel, Ekelund, Ulf“…DISCUSSION: An ML model based on age, sex, ECG and blood tests at ED arrival can identify six out of ten chest pain patients for safe early rule-out or rule-in with no need for serial blood tests. Future studies should attempt to improve these ML models further, e.g. by including additional input data. …”
Publicado 2023
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20503por Torrico, Faustino, Gascón, Joaquim, Ortiz, Lourdes, Pinto, Jimy, Rojas, Gimena, Palacios, Alejandro, Barreira, Fabiana, Blum, Bethania, Schijman, Alejandro Gabriel, Vaillant, Michel, Strub-Wourgaft, Nathalie, Pinazo, Maria-Jesus, Bilbe, Graeme, Ribeiro, Isabela“…The primary endpoint was sustained parasitological clearance by serial negative qPCR from end of treatment (EOT) until 6 months follow-up in the intention-to-treat (ITT) population. …”
Publicado 2022
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20504por Zhu, Xiao-Na, Wei, Yu-Sheng, Yang, Qian, Liu, Hao-Ran, Zhi, Zhe, Zhu, Di, Xia, Li, Hong, Deng-Li, Yu, Yun, Chen, Guo-Qiang“…Although conditional deletion of Fbxo22 in hematopoietic cells did not significantly affect the function of hematopoietic stem cells, MLL-AF9-induced leukemogenesis was dramatically abrogated upon Fbxo22 deletion, together with remarkably reduced LSCs after serial transplantations. Mechanistically, FBXO22 promoted degradation of BACH1 in MLLr AML cells, and overexpression of BACH1 suppressed MLLr AML progression. …”
Publicado 2023
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20505por Bhattacharya, Bisakh, Damle, Nishikant, Ranjan, Piyush, Arora, Geetanjali, Prakash, Sneha, Nischal, Neeraj, Jorwal, Pankaj, Kumar, Arvind, Tyagi, Apoorva, Wig, Naveet“…Whole-body anteroposterior planar imaging was done from 15 min after injection at serial intervals till 4–6 h along with one single-photon emission computed tomography–computed tomography (SPECT-CT) imaging with the help of a dual-head SPECT-CT gamma camera. …”
Publicado 2022
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20506por Okumura, Yasuo, Nagashima, Koichi, Watanabe, Ryuta, Yokoyama, Katsuaki, Kato, Takeshi, Fukaya, Hidehira, Hayashi, Hidemori, Nakahara, Shiro, Shimizu, Wataru, Iwasaki, Yu-ki, Fujimoto, Yuhi, Mukai, Yasushi, Ejima, Koichiro, Otsuka, Takayuki, Suzuki, Shinya, Murakami, Masato, Kimura, Masaomi, Harada, Masahide, Koyama, Junjiroh, Okamatsu, Hideharu, Yamane, Teiichi, Yamashita, Seigo, Tokuda, Michifumi, Narui, Ryohsuke, Takami, Mitsuru, Shoda, Morio, Harada, Tomoo, Nakajima, Ikutaro, Fujiu, Katsuhito, Hiroshima, Kenichi, Tanimoto, Kojiro, Fujino, Tadashi, Nakamura, Keijiro, Kumagai, Koji, Okada, Ayako, Kobayashi, Hideki, Hayashi, Tatsuya, Watari, Yuji, Hatsuno, Mina, Tachibana, Eizo, Iso, Kazuki, Sonoda, Kazumasa, Aizawa, Yoshiyasu, Chikata, Akio, Sakagami, Satoru, Inoue, Masaru, Minamiguchi, Hitoshi, Makino, Nobuhiko, Satomi, Kazuhiro, Yazaki, Yoshinao, Aoyagi, Hideshi, Ichikawa, Makoto, Haruta, Hironori, Hiro, Takafumi, Okubo, Kimie, Arima, Ken, Tojo, Taiki, Kihara, Hajime, Miyanaga, Satoru, Fukuda, Yoshiaki, Oiwa, Koji, Fujiishi, Tamami, Akabane, Masashi, Ishikawa, Norikazu, Kusano, Kengo, Miyamoto, Koji, Tabuchi, Haruna, Shiozawa, Tomoyuki, Miyamoto, Kenjiro, Mase, Hiroshi, Murotani, Kenta“…We will collect standard clinical background information plus each patient’s Clinical Frailty Scale score, AF-related symptoms, QoL (Five-Level Version of EQ-5D) scores, Mini-Mental State Examination (optional) score and laboratory test results, including measures of nutritional status, on entry into the study and 1 year later, and serial changes in symptoms and QoL will also be secondary endpoints. …”
Publicado 2023
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20507por Bann, Carla M., Newman, Jamie E., Poindexter, Brenda, Okoniewski, Katherine, DeMauro, Sara, Lorch, Scott A., Wilson-Costello, Deanne, Ambalavanan, Namasivayam, Peralta-Carcelen, Myriam, Limperopoulos, Catherine, Kapse, Kushal, Davis, Jonathan M., Walsh, Michele, Merhar, Stephanie“…Rather than conducting neuroimaging at a single time point, the study will include serial MRI assessments from birth to 2 years, allowing for the examination of trajectories throughout this period of rapid brain development. …”
Publicado 2022
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20508por Cremaschi, Andrea, Yang, Wenjian, De Iorio, Maria, Evans, William E., Yang, Jun J., Rosner, Gary L.“…Our results highlight that drug sensitivity profiles and leukemic subtypes play an important role in the response to induction therapy as measured by serial MRD measures.…”
Publicado 2023
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20509por Marastoni, Stefano, Madariaga, Ainhoa, Pesic, Aleksandra, Nair, Sree Narayanan, Li, Zhu Juan, Shalev, Zvi, Ketela, Troy, Colombo, Ilaria, Mandilaras, Victoria, Cabanero, Michael, Bruce, Jeff P., Li, Xuan, Garg, Swati, Wang, Lisa, Chen, Eric X., Gill, Sarbjot, Dhani, Neesha C., Zhang, Wenjiang, Pintilie, Melania, Bowering, Valerie, Koritzinsky, Marianne, Rottapel, Robert, Wouters, Bradly G., Oza, Amit M., Joshua, Anthony M., Lheureux, Stephanie“…Pharmacodynamic measurements on serial biopsies demonstrated limited pharmacodynamic impact. …”
Publicado 2022
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20510“…CONCLUSIONS: These results suggest that serial dependence in duration perception is modality-specific. …”
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20511por Cheon, Dae Young, Han, Kyung do, Kim, Chi-hun, Oh, Mi Sun, Lee, Byung-Chul, Kim, Yerim, Lee, Sang-Hwa, Kim, Chulho, Lim, Jae-Sung, Lee, Minwoo, Yu, Kyung-Ho“…This study included 223,426 patients with a new diagnosis of ischemic stroke between 2010 and 2016 who underwent two serial ambulatory health checkups. The participants were divided into four categories according to their habit change or regular exercise: persistent non-exercisers, new exercisers, exercise dropouts, and exercise maintainers. …”
Publicado 2023
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20514por Rossi, Leonardo Paolo“…Data cables must be capable of handling up to 5 Gb/s and must be electrical in nature within the volume of the pixel detector; conversion to optical signals will take place at larger radii where the radiation background is less intense. Serial powering has been chosen as the baseline for the ITk pixel system as it minimises service cable mass; extensive testing is being carried out to prove its feasibility. …”
Publicado 2018
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20515por Friedmann, Erika, Gee, Nancy R, Simonsick, Eleanor M, Barr, Erik, Resnick, Barbara, Werthman, Emily, Adesanya, Ikmat“…RESEARCH DESIGN AND METHODS: A total of 637 men (44.1%) and women aged 50–100 years (M = 68.3, standard deviation [SD] = 9.6) completed a comprehensive pet ownership questionnaire that ascertained pet ownership history 10–13 years and had serial assessments of physical function every 1–4 years prior. …”
Publicado 2022
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20516por Andtbacka, Robert H.I., Wang, Yan, Pierce, Robert H., Campbell, Jean S., Yushak, Melinda, Milhem, Mohammed, Ross, Merrick, Niland, Katie, Arbeit, Robert D., Parasuraman, Sudha, Bickley, Kris, Yeung, Cecilia CS, Aicher, Lauri D., Smythe, Kimberly S., Gan, Lu“…EXPERIMENTAL DESIGN: Serial biopsies of melanoma lesions were assessed after 3 weeks of mavorixafor monotherapy and after 6 weeks of combination treatment for immune cell markers by NanoString analysis for gene expression and by multiplexed immunofluorescent staining for in situ protein expression. …”
Publicado 2022
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20517por LeWitt, Peter, Liang, Grace S., Olanow, C. Warren, Kieburtz, Karl D., Jimenez, Roland, Olson, Kurt, Klepitskaya, Olga, Loewen, Gordon“…Participants received Q3H or Q4H CD/LD on days 1, 2, and 15 and their usual CD/LD regimen on other days. Serial blood samples were collected to determine plasma opicapone, LD, and 3-OMD concentrations and erythrocyte soluble COMT (S-COMT) activity. …”
Publicado 2023
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20518por Jenabi, Nastaran, Sadeghian, Susan, Karimzadeh, Fathallah, Pour, Maryam Safavi, Rakhshan, Vahid“…Antibacterial effects of the produced materials on S. mutans were evaluated by colony count with serial dilution method (n = 7 groups × 10 [n = 70] specimens) and agar disc diffusion test (n = 6 groups × 5 [n = 30] composite specimens + n = 6 groups × 5 [n = 30] light-cured bonding + n = 6 groups × 5 [n = 30] uncured bonding) against negative control and cefotaxime antibiotic. …”
Publicado 2023
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20519por Zhao, Junhua, Han, Zhaojun, Xu, Chang, Li, Lu, Pei, Haimeng, Song, Yongxi, Wang, Zhenning, Tang, Bo“…At last, the results through a serial expression analysis showed that YAP1 and HER-2 have discordant expression during metastasis. …”
Publicado 2023
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20520“…We modeled longitudinal changes in diabetic individuals using a linear mixed-effects (LME) framework and obtained i) the distribution of individual trajectories with and without GSH supplementation and ii) the overall rates of changes in the different study arms. Serial changes in elder and younger diabetic individuals were also modeled independently to examine differences in their progression. …”
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