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  1. 21041
    “…Feasibility and safety of the regimen was evaluated using serial visual analog scale (VAS, 0–10) values for self-reported pain, and examining changes in the magnitude of mean eccentric power as a function of movement velocity. …”
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    Eccentric Exercise Program Design: A Periodization Model for Rehabilitation Applications
  2. 21042
    “…We evaluated the feasibility of detecting resistance to anti-HER2 therapy by serial gene-panel ctDNA sequencing. RESULTS: Primary therapeutic resistance was identified in 6 out of 14 patients with events of progressive disease. …”
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    ctDNA dynamics: a novel indicator to track resistance in metastatic breast cancer treated with anti-HER2 therapy
  3. 21043
    “…The significant reduction in initial tumorigenicity and subsequent abrogation upon serial xenografting suggests potential elimination of the NB CSC fraction. …”
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    Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma
  4. 21044
    por Shipp, Stewart
    Publicado 2016
    “…Each pathway utilises a serial chain of inhibition, with two such links, or three, providing positive and negative feedback, respectively. …”
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    The functional logic of corticostriatal connections
  5. 21045
    “…Knowledge about the biological variation is needed for proper interpretation of serial measurements. Therefore, we aimed to determine and compare the biological variation of a large panel of biomarkers in healthy subjects and in patients with chronic HF. …”
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    Variability of biomarkers in patients with chronic heart failure and healthy controls
  6. 21046
    “…The expression of α(v)β(3) and CD31was significantly higher in the joints of rheumatoid arthritis rats compared to normal controls. In serial (99m)Tc-3PRGD2 scintigraphy studies, (99m)Tc-3PRGD2 uptake increased in parallel with disease progression. …”
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    Early detection of rheumatoid arthritis in rats and humans with 99mTc-3PRGD2 scintigraphy: imaging synovial neoangiogenesis
  7. 21047
    “…For safety monitoring, each treatment was followed by dosimetry with serial quantitative SPECT as well as inpatient and outpatient recording of adverse events. …”
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    Preliminary experience with dosimetry, response and patient reported outcome after (177)Lu-PSMA-617 therapy for metastatic castration-resistant prostate cancer
  8. 21048
    “…Strain TPX1 with overexpressed KmTPX1 gene showed an enhanced tolerance to oxidative stresses. Serial dilution assay indicated that KmTPX1 gene contributed to a better cellular growth behavior, when the cells were exposed to multiple lignocellulose-derived inhibitors, such as formic acid, acetic acid, furfural, ethanol, and salt. …”
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    Enhanced fermentative performance under stresses of multiple lignocellulose-derived inhibitors by overexpression of a typical 2-Cys peroxiredoxin from Kluyveromyces marxianus
  9. 21049
    “…The association between dog rabies cases and human population density was investigated using Mixed-effects models and epidemiological parameters such as the basic reproduction number (R(0)), the incubation and infectious period and the serial interval were estimated. A total of 4,632 animal rabies cases were reported, mainly in dogs (99.0%, 4,584 cases) during two epidemics from 1914 to 1921, and 1922 to 1933 respectively. …”
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    The rise and fall of rabies in Japan: A quantitative history of rabies epidemics in Osaka Prefecture, 1914–1933
  10. 21050
    “…METHODS: Blood was obtained from 166 adult trauma patients at the trauma scene, emergency room (ER), and serially afterwards. Circulating levels of DAMPs and cytokines were determined. …”
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    Plasma levels of danger-associated molecular patterns are associated with immune suppression in trauma patients
  11. 21051
    “…After achieving presumed steady-state on levetiracetam 1000 mg q12h, serial plasma samples (pre- and post-filter) and effluent samples were drawn at 2, 4, 6, 8, and 10 h. …”
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    Levetiracetam Pharmacokinetics in a Patient with Intracranial Hemorrhage Undergoing Continuous Veno-Venous Hemofiltration
  12. 21052
    “…Immunostaining and histological analyses were performed on sections from human retinal tissues and a patient prostate biopsy. RESULTS: Serial multimodal retinal imaging, microperimetry and adaptive optics photography demonstrated a paravascular distribution of placoid lesions characterized by hyper-reflectivity within the outer nuclear layer resembling type 2 acute macular neuroretinopathy. …”
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    Acute progressive paravascular placoid neuroretinopathy with negative-type electroretinography in paraneoplastic retinopathy
  13. 21053
    “…Ten patients with prostate cancer and verified bone metastases were prospectively included. All underwent two serial 18F-fluoride PET/CT at 1 h post-injection. …”
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    Repeatability of quantitative parameters of 18F-fluoride PET/CT and biochemical tumour and specific bone remodelling markers in prostate cancer bone metastases
  14. 21054
    por Pacik, Peter T., Geletta, Simon
    Publicado 2017
    “…CONCLUSION: A multimodal program that treated the physical and psychologic aspects of vaginismus enabled women to achieve pain-free intercourse as noted by patient communications and serial female sexual function studies. Further studies are indicated to better understand the individual components of this multimodal treatment program. …”
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    Vaginismus Treatment: Clinical Trials Follow Up 241 Patients
  15. 21055
    “…METHODS: 110 women (67 exposed to CHC) were drawn from the Pediatric Bone Mineral Accrual Study (PBMAS). Serial measures of total body (TB), lumbar spine (LS) and femoral neck (FN) BMC and aBMD were assessed by DXA (a total of 950 scans) and aligned by biological age (BA, years from peak height velocity [PHV]). …”
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    The associations of exposure to combined hormonal contraceptive use on bone mineral content and areal bone mineral density accrual from adolescence to young adulthood: A longitudinal study
  16. 21056
    “…Ep+CIRs displayed similarity with Ep+HCC cells including upregulated expression of stemness and Notch pathway genes, enhanced self‐renewal in serial spheroid assay and generation of subcutaneous tumors in nonobese diabetic/severe combined immunodeficiency mice. …”
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    EpCAM+ Liver Cancer Stem‐Like Cells Exhibiting Autocrine Wnt Signaling Potentially Originate in Cirrhotic Patients
  17. 21057
    “…We evaluated HLA DR3 transgenic (tg) “humanized” mice as a potential model of ATR and assessed the possibility of using this animal model for tick protective vaccine discovery studies. Serial tick infestations with pathogen-free Ixodes scapularis ticks were used to tick-bite sensitize HLA DR3 tg mice. …”
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    Partial pathogen protection by tick-bite sensitization and epitope recognition in peptide-immunized HLA DR3 transgenic mice
  18. 21058
    “…To directly measure how drug resistance spreads within a host and to assess how spatial structure impacts its emergence, we examined serial sequences from four macaques infected with RT-SHIV(mne027), a simian immunodeficiency virus encoding HIV-1 reverse transcriptase (RT), and treated with RT inhibitors. …”
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    A spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host
  19. 21059
    por Samotus, Olivia, Lee, Jack, Jog, Mandar
    Publicado 2017
    “…METHODS: A total of 28 PD and 24 ET participants with bothersome, disabling tremor, received six serial BoNT-A treatments every 16 weeks starting at week 0 with a follow-up visit 6 weeks following a treatment, totaling 96 weeks. …”
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    Long-term tremor therapy for Parkinson and essential tremor with sensor-guided botulinum toxin type A injections
  20. 21060
    “…At the end of each treatment period, subjects underwent predose sampling for concentrations of follicle‐stimulating hormone, luteinizing hormone, and progesterone and serial PK sampling for plasma LNG, EO, and CAB concentrations. …”
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    Lack of effect of oral cabotegravir on the pharmacokinetics of a levonorgestrel/ethinyl oestradiol‐containing oral contraceptive in healthy adult women
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