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  1. 21781
    “…METHODS: We report on six infants diagnosed with TSC pre- or perinatally, who underwent serial Video-EEG recordings during the first two years of life. …”
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    Electro-clinical and neurodevelopmental outcome in six children with early diagnosis of tuberous sclerosis complex and role of the genetic background
  2. 21782
    “…RespiFinder-22(®) a commercial multiplex NAT served as reference test. Serial 10-fold dilutions of influenza-A and -B cell culture supernatants were examined. …”
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    Diagnostic performance of near-patient testing for influenza
  3. 21783
    “…Anti-SARS-CoV IgG antibody was detected using indirect immunofluorescence technique and quantified by two-fold serial dilutions. Characteristics of patients who seroconverted “early” (<median interval) were compared to those documented to remain sero-negative during the same time interval. …”
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    Anti-SARS-CoV IgG response in relation to disease severity of severe acute respiratory syndrome
  4. 21784
    “…Furthermore, vaccination with the LDT3-A vaccine, which was derived from the tl/CH/LDT3/03 strain by serial passaging in chicken eggs, provided good protection against challenge with the tl/CH/LDT3/03 strain, in contrast to the poor protection offered with the H120 vaccine. …”
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    Altered pathogenicity of a tl/CH/LDT3/03 genotype infectious bronchitis coronavirus due to natural recombination in the 5′- 17 kb region of the genome
  5. 21785
    por Jung, Kwonil, Hu, Hui, Saif, Linda J.
    Publicado 2016
    “…We conducted histologic analysis and immunofluorescence (IF) staining for the detection of PDCoV antigens, and TUNEL assay in singly or serially cut tissue sections from the small and large intestines of four, 11- to 14-day-old gnotobiotic pigs, inoculated orally with 8.8–11.0 log(10) genomic equivalents (GE) of US PDCoV strains OH-FD22 or OH-FD100 (n = 3), or mock (n = 1). …”
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    Porcine deltacoronavirus induces apoptosis in swine testicular and LLC porcine kidney cell lines in vitro but not in infected intestinal enterocytes in vivo
  6. 21786
    “…Resistant mutants arose after serial passages in the presence of vivo-MO-1, but none were isolated against vivo-MO-2. …”
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    Inhibition of enterovirus 71 infection by antisense octaguanidinium dendrimer-conjugated morpholino oligomers
  7. 21787
    “…Workshop participants recommended that future efforts to replace animal use give priority to vaccines (1) that use large numbers of animals per test and for which many serials are produced annually, (2) that involve significant animal pain and distress during procedures, (3) for which the functional protective antigen has been identified, (4) that involve foreign animal/zoonotic organisms that are dangerous to humans, and (5) that involve pathogens that can be easily spread to wildlife populations. …”
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    Non-animal replacement methods for veterinary vaccine potency testing: state of the science and future directions
  8. 21788
    “…The lack of serial biopsies in patients with a range of carcinomas has been one obstacle in our understanding of the mechanism of action of immuno-oncology agents as well as the elucidation of mechanisms of resistance to these novel therapeutics. …”
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    The Use of a Humanized NSG-β2m(−/−) Model for Investigation of Immune and Anti-tumor Effects Mediated by the Bifunctional Immunotherapeutic Bintrafusp Alfa
  9. 21789
    “…The objective of this study was to explore the association between early measurements of copeptin, circulatory status, and short-term survival after out-of-hospital cardiac arrest. METHODS: Serial blood samples were collected at 24, 48, and 72 h as part of the target temperature management at 33 °C versus 36 °C after cardiac arrest trial, an international multicenter randomized trial where unconscious survivors after out-of-hospital cardiac arrest were allocated to an intervention of 33 or 36 °C for 24 h. …”
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    Copeptin as a marker of outcome after cardiac arrest: a sub-study of the TTM trial
  10. 21790
    por Shen, Christopher Y.
    Publicado 2020
    “…In addition, the study identified the existence of heteroskedasticity and positive serial correlation within residuals in some provinces and countries. …”
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    Logistic growth modelling of COVID-19 proliferation in China and its international implications
  11. 21791
    “…The progression of CAA was monitored using serial echocardiography for six months. We performed multivariable logistic regression analysis on the laboratory test and PNI with the disease outcome of the KD patients. …”
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    Prognostic nutrition index as a predictor of coronary artery aneurysm in Kawasaki Disease
  12. 21792
    “…METHODS: This was a study of adult patients in a large Australian tertiary hospital who had serial troponin testing commenced within the ED. Data from two periods were utilized; the pre-implementation period (8th April 2012 to 5th April 2014) and the post-implementation period (6th April 2014 to 2nd April 2016). …”
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    Examining the translational success of an initiative to accelerate the assessment of chest pain for patients in an Australian emergency department: a pre-post study
  13. 21793
    “…METHODS: Immunocompetent, previously healthy, adult patients receiving ambulatory treatment for a first episode of tuberculosis were prospectively followed up with serial lung physiology and quantitative computed tomography (CT) lung scans performed at diagnosis of tuberculosis, 2, 6, 12 and 18 months during and after the completion of treatment. …”
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    Transition from Restrictive to Obstructive Lung Function Impairment During Treatment and Follow-Up of Active Tuberculosis
  14. 21794
    “…METHODS: A prospective study comprising of 19 participants (13 females, mean age 50.4 ± 6.2 years, mean body mass index (BMI) 54 ± 14 kg/m(2), 17 type 2 diabetes) undergoing bariatric surgery (10 sleeve gastrectomy, 6 biliopancreatic diversion, 2 Roux-en-Y gastric bypass and 1 laparoscopic adjustable gastric banding). Serial measurements of the above markers were made pre-operatively, 1 and 6 months and 4 years post-operatively. …”
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    Temporal Effects of Bariatric Surgery on Adipokines, Inflammation and Oxidative Stress in Subjects with Impaired Glucose Homeostasis at 4 Years of Follow-up
  15. 21795
    “…Oesophageal AET limits for GORD detection were utilized as gold standards to generate serial receiver operator characteristics (ROC) curves to assess the sensitivity and specificity of current impedance GORD detection limits and identify optimized impedance standards based on area under the curve (AUC) analysis. …”
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    Optimization of impedance-measured reflux events in GORD utilizing acid exposure time
  16. 21796
    por Kurth, Florian, Roennefarth, Maria, Thibeault, Charlotte, Corman, Victor M., Müller-Redetzky, Holger, Mittermaier, Mirja, Ruwwe-Glösenkamp, Christoph, Heim, Katrin M., Krannich, Alexander, Zvorc, Saskia, Schmidt, Sein, Kretzler, Lucie, Dang-Heine, Chantip, Rose, Matthias, Hummel, Michael, Hocke, Andreas, Hübner, Ralf H., Opitz, Bastian, Mall, Marcus A., Röhmel, Jobst, Landmesser, Ulf, Pieske, Burkert, Knauss, Samuel, Endres, Matthias, Spranger, Joachim, Mockenhaupt, Frank P., Tacke, Frank, Treskatsch, Sascha, Angermair, Stefan, Siegmund, Britta, Spies, Claudia, Weber-Carstens, Steffen, Eckardt, Kai-Uwe, Schürmann, Dirk, Uhrig, Alexander, Stegemann, Miriam S., Zoller, Thomas, Drosten, Christian, Suttorp, Norbert, Witzenrath, Martin, Hippenstiel, Stefan, von Kalle, Christof, Sander, Leif Erik
    Publicado 2020
    “…We collect data on epidemiology, demography, medical history, symptoms, clinical course, and pathogen testing and treatment. Systematic, serial blood sampling will allow deep molecular and immunological phenotyping, transcriptomic profiling, and comprehensive biobanking. …”
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    Studying the pathophysiology of coronavirus disease 2019: a protocol for the Berlin prospective COVID-19 patient cohort (Pa-COVID-19)
  17. 21797
    “…METHODS: This retrospective study enrolled 16 real-time reverse transcription polymerase chain reaction-confirmed symptomatic patients with COVID-19 and 58 COVID-19 negative patients at a medical center in Taiwan over a 3-month period. Serial serum samples were collected and tested for antibody response using four point-of-care (POC) lateral flow immunoassays (LFIA) (ALLTEST 2019-nCoV IgG/IgM Rapid Test, Dynamiker 2019-nCoV IgG/IgM Rapid Test, ASK COVID-19 IgG/IgM Rapid Test, and Wondfo SARS-CoV-2 Antibody Test). …”
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    Four point-of-care lateral flow immunoassays for diagnosis of COVID-19 and for assessing dynamics of antibody responses to SARS-CoV-2
  18. 21798
    “…All patients had undergone serial CT scanning before SBRT and after completion of SBRT. …”
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    The CT appearance pattern of radiation-induced lung injury and tumor recurrence after stereotactic body radiation therapy in early stage non-small cell lung cancer
  19. 21799
    por Bhume, Rahul J, Babaliche, Prakash
    Publicado 2020
    “…When tests were used in parallel combination, 97.01% sensitivity was attained, while the specificity dropped to 46.30%. When used in serial combination, sensitivity of 85.07% and specificity of 85.19% were observed. …”
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    Clinical Profile and the Role of Rapid Serological Tests: Typhifast IgM and Enterocheck WB in the Diagnosis of Typhoid Fever
  20. 21800
    “…The oral contraceptive was administered alone on days 12–25 and with vixotrigine 150 mg three times daily on days 26–32. Serial blood samples were collected for pharmacokinetic analysis. …”
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    Evaluation of the Potential Pharmacokinetic Interactions Between Vixotrigine and an Oral Contraceptive
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