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  1. 22241
    “…The smaller species is produced by matrix metalloprotease/ADAM-mediated proteolysis (shown by the use of pharmacological inhibitors) and has a molecular weight identical to that of a mutant lacking the entire N-terminus, Δ122 GPR37L1. Serial truncation of the N-terminus prevented GPR37L1 expression except when the entire N-terminus was removed, narrowing the predicted site of N-terminal proteolysis to residues 105–122. …”
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    The N-terminus of GPR37L1 is proteolytically processed by matrix metalloproteases
  2. 22242
    “…The storytelling intervention will be delivered by DVDs with serial installments at baseline and at 3, 6, and 9 months after trial enrollment. …”
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    Conquering hypertension in Vietnam—solutions at grassroots level: study protocol of a cluster randomized controlled trial
  3. 22243
    “…Participants from two subsequent visits of the Rotterdam Study were included. All underwent serial abdominal ultrasonography (median follow-up: 4.4 years) and filled in a food frequency questionnaire. …”
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    Adherence to a plant-based, high-fibre dietary pattern is related to regression of non-alcoholic fatty liver disease in an elderly population
  4. 22244
    “…Plasma dilution derived from serial hemoglobin concentration and red blood cell count served as input variables for group and individual fluid volume kinetic analyses using a non-linear mixed effects model. …”
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    Evaluation of the Distribution and Elimination of Balanced Isotonic Crystalloid, 5% Hypertonic Saline, and 6% Tetrastarch 130/0.4 Using Volume Kinetic Modeling and Analysis in Healthy Conscious Cats
  5. 22245
    “…METHODS: Neurocognitive performance, mental health and cognitive symptoms were assessed using computerised tests (CNS-vital signs), paper pen tests (Category fluency, Trail-Making Test, Digit Span, Paced Auditory Serial Addition Test), questionnaires (Hospital Anxiety and Depression Scale, SF-36v2 Health Survey) and a symptom checklist. …”
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    Neurocognitive performance and mental health of retired female football players compared to non-contact sport athletes
  6. 22246
    “…Following IPSE exposure, mice were serially weighed and organs analyzed by histology to assess for toxicity. …”
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    IPSE, a urogenital parasite-derived immunomodulatory molecule, suppresses bladder pathogenesis and anti-microbial peptide gene expression in bacterial urinary tract infection
  7. 22247
    “…METHODS: In this prospective cohort study, 21 critically ill COVID-19 patients treated with anakinra were compared to a group of standard care. Serial data of clinical inflammatory parameters and concentrations of multiple circulating cytokines were determined and aligned on start day of anakinra in the treatment group, and median start day of anakinra in the control group. …”
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    Anakinra treatment in critically ill COVID-19 patients: a prospective cohort study
  8. 22248
    “…Hepatic histological examination and hepatic and exosomal miRNA expression analysis were serially performed using next-generation sequencing (NGS). …”
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    Comprehensive analysis of liver and blood miRNA in precancerous conditions
  9. 22249
    “…Patients will be followed for 12 months post-treatment with serial imaging, biomarkers, toxicity assessment and quality of life assessment. …”
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    Single-arm prospective interventional study assessing feasibility of using gallium-68 ventilation and perfusion PET/CT to avoid functional lung in patients with stage III non-small cell lung cancer
  10. 22250
    “…However, the reconstruction failed to retain the HV outflow and the anterior section became congested. Serial trials of surgical revisions including re-anastomosis, vein graft interposition and vein graft patch-plasty on the anastomotic wall failed to recover the HV outflow. …”
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    Urgent intraoperative endovascular stent placement to resolve acute hepatic or portal venous obstruction during liver surgery: a case series
  11. 22251
    “…The robotic platform offers a number of workflow advantages over traditional frame-based approaches, including parallel rather than serial operation in a bilateral case, decreased concern regarding human error in setting frame coordinates, and surgeon comfort.…”
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    Accuracy and Workflow Improvements for Responsive Neurostimulation Hippocampal Depth Electrode Placement Using Robotic Stereotaxy
  12. 22252
    “…Our IRB-approved study included 1367 serial CXRs from 405 adult patients (mean age 65 ± 16 years) from two sites in the US (Site A) and South Korea (Site B). …”
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    Artificial intelligence matches subjective severity assessment of pneumonia for prediction of patient outcome and need for mechanical ventilation: a cohort study
  13. 22253
    por Augusto, João B, Menacho, Katia, Andiapen, Mervyn, Bowles, Ruth, Burton, Maudrian, Welch, Sophie, Bhuva, Anish N, Seraphim, Andreas, Pade, Corinna, Joy, George, Jensen, Melanie, Davies, Rhodri H, Captur, Gabriella, Fontana, Marianna, Montgomery, Hugh, O’Brien, Ben, Hingorani, Aroon D, Cutino-Moguel, Teresa, McKnight, Áine, Abbass, Hakam, Alfarih, Mashael, Alldis, Zoe, Baca, Georgina L, Boulter, Alex, Bracken, Olivia V, Bullock, Natalie, Champion, Nicola, Chan, Carmen, Couto-Parada, Xose, Dieobi-Anene, Keenan, Feehan, Karen, Figtree, Gemma, Figtree, Melanie C, Finlay, Malcolm, Forooghi, Nasim, Gibbons, Joseph M, Griffiths, Peter, Hamblin, Matt, Howes, Lee, Itua, Ivie, Jones, Meleri, Jardim, Victor, Kapil, Vikas, Jason Lee, Wing-Yiu, Mandadapu, Vineela, Mfuko, Celina, Mitchelmore, Oliver, Palma, Susana, Patel, Kush, Petersen, Steffen E, Piniera, Brian, Raine, Rosalind, Rapala, Alicja, Richards, Amy, Sambile, Genine, Couto de Sousa, Jorge, Sugimoto, Michelle, Thornton, George D, Artico, Jessica, Zahedi, Dan, Parker, Ruth, Robathan, Mathew, Hickling, Lauren M, Ntusi, Ntobeko, Semper, Amanda, Brooks, Tim, Jones, Jessica, Tucker, Art, Veerapen, Jessry, Vijayakumar, Mohit, Wodehouse, Theresa, Wynne, Lucinda, Treibel, Thomas A, Noursadeghi, Mahdad, Manisty, Charlotte, Moon, James C
    Publicado 2020
    “…We established a bioresource with serial sampling of health care workers (HCWs) designed to obtain samples before and during mainly mild disease, with follow-up sampling to evaluate the quality and duration of immune memory. …”
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    Healthcare Workers Bioresource: Study outline and baseline characteristics of a prospective healthcare worker cohort to study immune protection and pathogenesis in COVID-19
  14. 22254
    “…ASCs were injected into the site of tendinopathy (identified by ultrasound imaging at the origin of the common extensor tendon) on a single occasion followed by physiotherapy. Players underwent serial clinical evaluations during a 12-month period and repeated MRI at 6-month post-injection. …”
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    Promising improvement of chronic lateral elbow tendinopathy by using adipose derived mesenchymal stromal cells: a pilot study
  15. 22255
    “…Strategies involving serial RT-PCR testing must be rigorously evaluated.…”
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    Predictors of negative first SARS-CoV-2 RT-PCR despite final diagnosis of COVID-19 and association with outcome
  16. 22256
    “…The balance test included three levels of difficulties of posture tasks (eyes-open vs. eyes-closed vs. one-leg stance) and three cognitive tasks (without cognitive task vs. auditory arithmetic task vs. serial-7 s arithmetic task). RESULTS: A repeated-measure analysis of variance (3 postural tasks × 3 congnitive tasks× 2 groups) testing the effects of the different congnitive task levels on the performance in different postural conditions. …”
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    How cognitive loads modulate the postural control of older women with low back pain?
  17. 22257
    “…The outcome measurements were: (a) Intraoperative fluoroscopy exposure and length of surgery and (b) Postoperative serial follow-up MRIs every 6 months. RESULTS: 22 female and 18 male patients aged 13.8 ± 1.6 years (range: 11–17 years) were included. …”
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    Electromagnetic navigation reduces radiation exposure for retrograde drilling in osteochondrosis dissecans of the talus
  18. 22258
    “…OBJECTIVE: The objective of this study was to explore if supplementary disability measures including the Timed 25-Foot Walk (T25FW), 9-Hole Peg Test (9HPT), and Paced Auditory Serial Addition Test (PASAT) significantly contribute additional information on health utility in RRMS and SPMS otherwise not captured by the EDSS and relapses and, therefore, should be considered in future economic evaluations of disease-modifying therapies. …”
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    Predictors of Health Utility in Relapsing–Remitting and Secondary-Progressive Multiple Sclerosis: Implications for Future Economic Models of Disease-Modifying Therapies
  19. 22259
    “…CONCLUSIONS: TOF MRA helps in identifying different residue patterns in coiled aneurysms. Serial follow-up MRA appears useful in showing the pattern and size changes in the residual aneurysm. …”
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    Getting More Out of Follow-up Three-Dimensional Time-of-Flight Magnetic Resonance Angiography in Endovascularly Treated Intracranial Aneurysms
  20. 22260
    “…Methods: We performed serial measurements of CT-pro-ET-1 in 361 consecutively enrolled ischemic stroke patients and assessed functional outcome and mortality after 90 days. …”
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    C-Terminal-Pro-Endothelin-1 Adds Incremental Prognostic Value for Risk Stratification After Ischemic Stroke
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