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  1. 22621
    “…BACKGROUND: Our aim was to examine whether serial blood lactate levels could be used as predictors of outcome. …”
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    Occult hypoperfusion is associated with increased mortality in hemodynamically stable, high-risk, surgical patients
  2. 22622
    “…Subjects (P1, N=14; P2, N=11) received daily single-dose oral MET (40–120mg) or BUP/NLX (8/2–24/6mg) based on their prescribed stable dose throughout, in addition to DCV (60mg QD) on Days 2–9. Serial PK sampling occurred predose and postdose till 24 hours on Day 1 (MET/BUP) and Day 10 (MET/BUP/DCV). …”
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    Evaluation of drug-drug interaction between daclatasvir and methadone or buprenorphine/naloxone
  3. 22623
    “…All doses of study drug were taken with a moderate-fat meal. Serial plasma PK samples and safety assessments were obtained throughout the study. …”
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    The effect of dolutegravir on the pharmacokinetics of metformin in healthy subjects
  4. 22624
    por Lakew, Yihunie, Tamene, Habtamu
    Publicado 2014
    “…Therefore, there is a need for robust intervention strategies such as tailored serial radio program targeting taxi drivers and their assistants.…”
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    HIV related risk behaviours among taxi drivers and their assistants in Addis Ababa, Ethiopia: descriptive cross-sectional survey
  5. 22625
    “…Hemolysis controls with serial dilutions of hemoglobin were prepared. RNA was extracted from serum, plasma or hemolyzed controls with spiked-in cel-miR-39, and levels of miR-21, miR-29a, miR-125b and miR-16 were examined by real-time RT-PCR. …”
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    Technical Factors Involved in the Measurement of Circulating MicroRNA Biomarkers for the Detection of Colorectal Neoplasia
  6. 22626
    “…Sixty-eight patients with RAAA were treated between February 2005 and June 2013. Serial measurements of Sequential Organ Failure Assessment score (SOFA), Simplified Acute Physiology Score II (SAPS II) and Simplified Therapeutic Intervention Scoring System-28 (TISS-28) were evaluated with respect to in-hospital mortality. …”
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    Early prediction of survival after open surgical repair of ruptured abdominal aortic aneurysms
  7. 22627
    por Wu, Kendra M, Riley, Steven
    Publicado 2014
    “…Dilution protocols more highly resolved than serial 2-fold dilution should be considered for serological surveys. …”
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    Simulation-guided design of serological surveys of the cumulative incidence of influenza infection
  8. 22628
    “…Only mild changes of BP were found with repeated MMF anaesthesia, so it seems suitable for serial use, unless the high BP and the low HR during the surgical plane of anaesthesia are undesirable for a special procedure.…”
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    Influence of repeated anaesthesia on physiological parameters in male Wistar rats: a telemetric study about isoflurane, ketamine-xylazine and a combination of medetomidine, midazolam and fentanyl
  9. 22629
    “…Such data are important in setting analytical quality specifications, assessing the utility of population reference intervals (index of individuality) and assessing the significance of changes in serial results from an individual (reference change value; RCV). …”
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    Evaluation of method performance for oxidative stress biomarkers in urine and biological variations in urine of patients with type 2 diabetes mellitus and diabetic nephropathy
  10. 22630
    “…Using a peptide-protein binding assay, we found that Nox2 peptides containing a (369)CysGlyCys(371) triad (CGC) bound p67(phox) with high affinity, dependent upon the establishment of a disulfide bond between the two cysteines. Serially truncated recombinant Nox2 DHR proteins bound p67(phox) only when they comprised the CGC triad. …”
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    The dehydrogenase region of the NADPH oxidase component Nox2 acts as a protein disulfide isomerase (PDI) resembling PDIA3 with a role in the binding of the activator protein p67(phox)
  11. 22631
    “…Indirect composite restorations were bonded using dual-cure cement under 500 g load for 5 min. The specimens were serially sectioned with a bonding area of ± 1.0 mm(2) in 3 regions: enamel (E), superficial dentin (SD) and deep dentin (DD). …”
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    EFFECT OF A BONDING RESIN LAYER ASSOCIATED WITH A SELF-ETCHING ADHESIVE SYSTEM ON THE BOND STRENGTH OF INDIRECT RESTORATIONS
  12. 22632
    “…We used BioMiCo to build models for three serially sampled datasets and tested their predictive accuracy across different time points. …”
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    BioMiCo: a supervised Bayesian model for inference of microbial community structure
  13. 22633
    “…A quantitative method based on serial sectioning of frozen head and surface measurements at the cutting plane was used to determine the volume of twenty different CSF compartments in rat brain on embryonic day 19 (E19), and postnatal days 2 (P2) and 9 (P9). …”
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    Changes in the cerebrospinal fluid circulatory system of the developing rat: quantitative volumetric analysis and effect on blood-CSF permeability interpretation
  14. 22634
    “…Recognizing proposed clinical and autoimmune similarities between SC and PANDAS (pediatric autoimmune neuropsychiatric disorder associated with a streptococcal infection), we sought to identify serial biomarker changes in a slightly different population. …”
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    Neuronal Antibody Biomarkers for Sydenham’s Chorea Identify a New Group of Children with Chronic Recurrent Episodic Acute Exacerbations of Tic and Obsessive Compulsive Symptoms Following a Streptococcal Infection
  15. 22635
    “…All 12 dogs were infected intravenously with a wild strain of E. canis on day 428 of the study. APP levels were serially measured during two periods: days 0–38 post-vaccination (groups 1 and 2) and days 0–39 post-challenge (groups 1, 2, 3). …”
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    Comparison of the acute phase protein and antioxidant responses in dogs vaccinated against canine monocytic ehrlichiosis and naive-challenged dogs
  16. 22636
    “…N-acetyl-DL-leucine, N-acetyl-L-leucine and N-acetyl-D-leucine on VC using behavioural testing and serial [(18)F]-Fluoro-desoxyglucose ([(18)F]-FDG)-μPET in a rat model of unilateral chemical labyrinthectomy (UL). …”
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    N-Acetyl-L-Leucine Accelerates Vestibular Compensation after Unilateral Labyrinthectomy by Action in the Cerebellum and Thalamus
  17. 22637
    “…The stability of label was also studied in in vivo mouse models by serial PET scans and ex vivo biodistribution following intravenous and intramyocardial injection of (89)Zr-labeled hMSCs. …”
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    Novel (89)Zr cell labeling approach for PET-based cell trafficking studies
  18. 22638
    “…Equivalent doses of these drugs were also injected into four polypropylene jars containing fresh human whole blood for drug stability testing. Serial blood samples were collected from the controls and the ECMO circuits over 24 hours, and the concentrations of the study drugs were quantified using validated chromatographic assays. …”
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    Protein-bound drugs are prone to sequestration in the extracorporeal membrane oxygenation circuit: results from an ex vivo study
  19. 22639
    por Abushammala, Issam
    Publicado 2015
    “…Period two, when each rabbit received a single dose of 70 mg CBZ-suspension co-administered with a single dose of 1.5 mg PG with a washout period of one week between the two periods. Serial blood samples were collected over a period of 48 h. …”
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    The Effect of Pioglitazone on Pharmacokinetics of Carbamazepine in Healthy Rabbits
  20. 22640
    “…As burn patients require serial surgical interventions for motor and cosmetic repair, restricting blood loss during operative intervention is optimal.…”
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    Propranolol attenuates hemorrhage and accelerates wound healing in severely burned adults
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