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  1. 22681
    “…However, p19(Arf) is required for replicative senescence, a condition associated with an activated DNA damage response, as p19(Ar)(f)−/− MEFs do not senesce after serial passage. A possible explanation for these seemingly disparate roles for p19(Arf) is that acute and chronic DNA damage responses are mechanistically distinct. …”
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    p19(Arf) is required for the cellular response to chronic DNA damage
  2. 22682
    “…Eligible subjects were allocated to one of two groups and received either levocetirizine OS 5 mg or cetirizine DS 10 mg under fasting conditions, and the alternate treatment after a 7-days washout period. Serial blood samples were taken after each administration, and plasma levocetirizine concentrations were determined using a validated LC-MS/MS method. …”
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    Comparison of levocetirizine pharmacokinetics after single doses of levocetirizine oral solution and cetirizine dry syrup in healthy Japanese male subjects
  3. 22683
    “…The virus hg-PR8 was obtained after 20 serial passages of A/Puerto Rico/8/1934 (PR8) in NIID-MDCK cells. …”
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    Development of an Influenza A Master Virus for Generating High-Growth Reassortants for A/Anhui/1/2013(H7N9) Vaccine Production in Qualified MDCK Cells
  4. 22684
    “…Eleven patients were analyzed using established method. Serial PB and/or BM samples (n=71) were taken in 1-3 months intervals (mean 1.5-month intervals) and median follow-up duration after chemotherapy was 11 months (5-28.5 months). …”
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    Evaluation of Minimal Residual Disease in Acute Myeloid Leukemia with NPM1 Marker
  5. 22685
    “…Moreover, ARISA patterns can be statistically analyzed to identify distinct subgroups and transitions between them as well as serial correlations. Thereby the microbial community and its structural development can be correlated with statistical relevance to changes in operational (feed) and process parameters (pH-value, biogas composition). …”
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    Process parameters and changes in the microbial community patterns during the first 240 days of an agricultural energy crop digester
  6. 22686
    “…Culture virus supernatant was harvested, and then the virus titer was determined by serial dilution assay. A549 cells were transduced with the constructed lentiviral vectors, and real-time polymerase chain reaction (RT-PCR) and Western blot were used to evaluate p66Shc expression. …”
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    Construction of p66Shc gene interfering lentivirus vectors and its effects on alveolar epithelial cells apoptosis induced by hyperoxia
  7. 22687
    “…Histology demonstrated that Qdot-loaded hMSCs remained present in the infarcted myocardium after 1 week. Analysis of serial sections of Masson's trichrome staining revealed that the greatest infarct size was in the infarct group (7.0% ± 2.2%), where unseeded (3.8% ± 0.6%) and hMSC-seeded (3.7% ± 0.8%) suture groups maintained similar infarct sizes. …”
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    Functional Effects of Delivering Human Mesenchymal Stem Cell-Seeded Biological Sutures to an Infarcted Heart
  8. 22688
    “…Volunteers were randomized to receive 11 g effervescent test formulation or the reference product under fasting conditions, after which 19 serial blood samples were collected over 48 hours. …”
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    Effervescent N-Acetylcysteine Tablets versus Oral Solution N-Acetylcysteine in Fasting Healthy Adults: An Open-Label, Randomized, Single-Dose, Crossover, Relative Bioavailability Study
  9. 22689
    “…The early-treatment group had better Paced Auditory Serial Addition Task–3 total scores (p = 0.0070). …”
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    The 11-year long-term follow-up study from the randomized BENEFIT CIS trial
  10. 22690
    “…In study one, predominantly Angus heifers were classified based on fertility using serial embryo transfer to select animals with intrinsic differences in pregnancy loss. …”
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    Identification of Beef Heifers with Superior Uterine Capacity for Pregnancy
  11. 22691
    “…Traditionally tissue samples are analysed using protein or enzyme specific stains on serial sections to build up a picture of the distribution of components contained within them. …”
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    Investigation of intervertebral disc degeneration using multivariate FTIR spectroscopic imaging
  12. 22692
    “…METHODS AND FINDINGS: We conducted a stratified, cluster-designed, serial cross-sectional household study from 2014–2015 in the Kilimanjaro Region, Tanzania. …”
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    Prevalence, Risk Factors, and Complications of Diabetes in the Kilimanjaro Region: A Population-Based Study from Tanzania
  13. 22693
    “…The Danube floodplain forests (third and still expanding focus) did not display relationship with any North American population; instead the Czech origin of the Danube population was indicated. A serial dilution of genetic diversity along the dispersion route across central and eastern Europe was observed. …”
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    Population structure and dispersal routes of an invasive parasite, Fascioloides magna, in North America and Europe
  14. 22694
    “…ONSD seen on ocular US can be a feasible method for detection and serial monitoring of ICP in Korean adult patients.…”
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    Optic nerve sheath diameter threshold by ocular ultrasonography for detection of increased intracranial pressure in Korean adult patients with brain lesions
  15. 22695
    “…Design: A British birth cohort study with prospective indicators of pubertal timing based on age at menarche, clinical assessment of pubertal stage, and growth tempo from serial height measures, and bone measures derived from peripheral quantitative computed tomography (pQCT) and dual-energy X-ray absorptiometry (DXA) at 60-64 years of age among 866 women and 792 men. …”
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    Pubertal timing and bone phenotype in early old age: findings from a British birth cohort study
  16. 22696
    por Tsukamoto, Yoshihiko, Omi, Naoko
    Publicado 2016
    “…This list includes all morphology types first outlined by Polyak (1941) using the Golgi method in the primate retina and subsequently identified by other researchers using electron microscopy (EM) combined with the Golgi method, serial section transmission EM (SSTEM), and immunohistochemical imaging. …”
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    ON Bipolar Cells in Macaque Retina: Type-Specific Synaptic Connectivity with Special Reference to OFF Counterparts
  17. 22697
    “…Those diagnosed with OBI were serially followed up at 12, 24 and 36 months of age. …”
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    Occult HBV Infection in Immunized Neonates Born to HBsAg-Positive Mothers: A Prospective and Follow-Up Study
  18. 22698
    “…The presence of myocardial fibrosis in some CFS patients suggests that CMR assessment of cardiac involvement is warranted as part of the scientific exploration, which may imply serial non-invasive examinations.…”
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    Chronic fatigue syndrome in women assessed with combined cardiac magnetic resonance imaging
  19. 22699
    “…However there exist only a few serial MRI studies of prion patients, and these mostly used whole brain summary measures or region of interest based approaches. …”
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    Neuroanatomical correlates of prion disease progression - a 3T longitudinal voxel-based morphometry study
  20. 22700
    “…Radiologic joint damage progression was assessed by changes in the total Sharp-van der Heijde score (SHS) on serial radiographs of the hands and feet. The independent association between these biomarker levels and the structural damage endpoint was examined using regression analysis RESULTS: The mean age of the 97 RA patients (68 women) at the time of the study was 54 ± 14 years, and the median disease duration was 1.6 ± 1.5 years. …”
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    Effect of Osteoprotegerin and Dickkopf-Related Protein 1 on Radiological Progression in Tightly Controlled Rheumatoid Arthritis
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