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23161por Li, Linghua, Liang, Yuanhao, Hu, Fengyu, Yan, Huanchang, Li, Yueping, Xie, Zhiwei, Huang, Liping, Zhao, Jianhui, Wan, Zhengwei, Wang, Haiying, Shui, Jingwei, Cai, Weiping, Tang, Shixing“…METHODS: Demographic and clinical information were obtained. Serial samples of blood, nasal and pharyngeal and anal swabs were collected at different time points post-onset. …”
Publicado 2020
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23162por Gheller, Brandon J., Blum, Jamie E., Fong, Ern Hwei Hannah, Malysheva, Olga V., Cosgrove, Benjamin D., Thalacker-Mercer, Anna E.“…Reducing levels of METTL3 in primary mouse MuSCs prior to transplantation enhanced their engraftment capacity upon primary transplantation, however their capacity for serial transplantation was lost. In conclusion, METTL3 regulates m(6)A levels in MuSCs/myoblasts and controls the transition of MuSCs/myoblasts to different cell states. …”
Publicado 2020
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23163“…Clinical challenges are encountered in the management of patients suffering from depression whether they are designated difficult-to-treat or treatment-resistant. Prospective serial depression treatment trials have shown that less than 40% of patients with major depressive disorder remit with an initial pharmacotherapy trial, and a progressively smaller proportion of patients remit with each subsequent trial. …”
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23164por Stoyanov, Kiril M, Biener, Moritz, Hund, Hauke, Mueller-Hennessen, Matthias, Vafaie, Mehrshad, Katus, Hugo A, Giannitsis, Evangelos“…While median TAT of the first hsTnT increased (53–57 min, p<0.001), total TAT of serial hsTnT did not increase significantly with higher crowding (p=0.170). …”
Publicado 2020
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23165por Bhardwaj, Vimal, Vikneswaran, Gunaseelan, Rola, Philippe, Raju, Siddharth, Bhat, Rammohan S, Jayakumar, Arunkumar, Alva, Arjun“…Patients underwent ultrasound examination with serial determination till AKI resolved or patient is initiated on dialysis. …”
Publicado 2020
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23166por Zhu, Guangwei, Cheng, Zhibin, Lin, Chunlin, Wang, Qin, Huang, Yongjian, Zheng, Wei, Yang, Shugang, Ye, Jianxin“…METHODS: qPCR analyzed miRNA-140 expression levels in colorectal cancer tissues, normal colorectal cancer tissues and colorectal cells including SW480 and HCT116 cancer cells and FHC normal colorectal epithetical cells. A serial biological experiment analyzed miRNA-140 effects on cell proliferation, migration and invasion capacities in SW480 and HCT116 cells. miRNA targeting gene prediction and a dual luciferase assay were used to analyze miRNA-140-targeted TRAF6. qPCR and Western blot analyzed miRNA-140 effects on the mRNA and protein expression of TRAF6. …”
Publicado 2020
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23167por Chiari, Catharina, Grgurevic, Lovorka, Bordukalo‐Niksic, Tatjana, Oppermann, Hermann, Valentinitsch, Alexander, Nemecek, Elena, Staats, Kevin, Schreiner, Markus, Trost, Carmen, Kolb, Alexander, Kainberger, Franz, Pehar, Sanja, Milosevic, Milan, Martinovic, Snjezana, Peric, Mihaela, Sampath, T Kuber, Vukicevic, Slobodan, Windhager, Reinhard“…Patients were followed for 0 to 24 months by clinical examination (safety) and computed tomography (CT) and serial radiographic analyses (efficacy). The results show that there were no detectable anti‐rhBMP6 antibodies in the blood of any of the 20 patients at 14 weeks after implantation. …”
Publicado 2020
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23168por Parent, Ephraim E., Patel, Dhruv, Nye, Jonathon A., Li, Zhuo, Olson, Jeffrey J., Schuster, David M., Goodman, Mark M.“…Lesions were characterized as either recurrent disease (11 of 15 lesions) or radiation necrosis (4 of 15 lesions) and confirmed with histopathological correlation (7 lesions) or through serial MRI studies (8 lesions). RESULTS: Time activity curve analysis found statistically greater radiotracer accumulation for all lesions, including radiation necrosis, when compared to contralateral normal brain. …”
Publicado 2020
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23169por Potluri, Hemanth K, Ng, Tun Lee, Newton, Michael A, Zhang, Jin, Maher, Christopher A, Nelson, Peter S, McNeel, Douglas G“…The patients with nmCSPC received treatment with either standard androgen deprivation therapy (ADT) or an antitumor DNA vaccine encoding prostatic acid phosphatase. Serial sera samples from these individuals were also used to probe the array, to secondarily determine whether this approach could be used to detect treatment-related changes. …”
Publicado 2020
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23170“…METHODS: Nanovesicles are made from intact iPSC-MSCs through serial extrusion. The selective uptake of fluorescently labeled nanovesicles by prostate cancer cells vs. non-tumor cells was examined with flow cytometry. …”
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23171por Higgins, Victoria, Fabros, Anselmo, Wang, Xiao Yan, Bhandari, Maria, Daghfal, David J., Kulasingam, Vathany“…CONCLUSION: The Abbott IgM assay exhibited the earliest response and greatest signal in most patients evaluated for serial sampling and had the highest NPV < 14 days post-PCR positivity, suggesting its potential utility as an adjunct test to PCR early in disease course.…”
Publicado 2021
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23172por Zhao, Jun, Xue, Qiaoyi, Chen, Xing, You, Zhiwen, Wang, Zhe, Yuan, Jianmin, Liu, Hui, Hu, Lingzhi“…A consistent correction method should be applied for serial PET/MR scans. The Dixon method provides the most accurate measure of LBM, yielding the least bias of all approaches when compared to DXA. …”
Publicado 2021
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23173“…For PK and PD analyses, serial blood samples were collected up to 72 hours after dosing to determine plasma concentrations of gemigliptin, its active metabolite LC15-0636 and rosuvastatin, and plasma dipeptidyl peptidase-4 (DPP-4) activity. …”
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23174por Wang, Yanqun, Wang, Daxi, Zhang, Lu, Sun, Wanying, Zhang, Zhaoyong, Chen, Weijun, Zhu, Airu, Huang, Yongbo, Xiao, Fei, Yao, Jinxiu, Gan, Mian, Li, Fang, Luo, Ling, Huang, Xiaofang, Zhang, Yanjun, Wong, Sook-san, Cheng, Xinyi, Ji, Jingkai, Ou, Zhihua, Xiao, Minfeng, Li, Min, Li, Jiandong, Ren, Peidi, Deng, Ziqing, Zhong, Huanzi, Xu, Xun, Song, Tie, Mok, Chris Ka Pun, Peiris, Malik, Zhong, Nanshan, Zhao, Jingxian, Li, Yimin, Li, Junhua, Zhao, Jincun“…METHODS: Using high-throughput sequencing of metatranscriptomic and hybrid captured libraries, we characterized consensus genomes and intra-host single nucleotide variations (iSNVs) of serial samples collected from eight patients with COVID-19. …”
Publicado 2021
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23175por Saw, Eng Leng, Pearson, James T., Schwenke, Daryl O., Munasinghe, Pujika Emani, Tsuchimochi, Hirotsugu, Rawal, Shruti, Coffey, Sean, Davis, Philip, Bunton, Richard, Van Hout, Isabelle, Kai, Yuko, Williams, Michael J. A., Kakinuma, Yoshihiko, Fronius, Martin, Katare, Rajesh“…Animals were followed up serially and samples collected at different time points for molecular and histological analysis of cardiac NNCS components and prosurvival and proangiogenic signaling pathways. …”
Publicado 2021
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23176por Forde, Karina, Resta, Nicoletta, Ranieri, Carlotta, Rea, David, Kubassova, Olga, Hinton, Mark, Andrews, Katrina A., Semple, Robert, Irvine, Alan D., Dvorakova, Veronika“…In patient one, alleviation of respiratory compromise was observed and functionally, seating and lying postures improved. Serial volumetric MRI analysis revealed 15% reduction in calculated volumes of fatty overgrowth between treatment commencement and end. …”
Publicado 2021
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23177por De, Brian, Ng, Sweet Ping, Liu, Amy Y, Avila, Santiago, Tao, Randa, Holliday, Emma B, Brownlee, Zachary, Kaseb, Ahmed, Lee, Sunyoung, Raghav, Kanwal, Vauthey, Jean-Nicolas, Minsky, Bruce D, Herman, Joseph M, Das, Prajnan, Smith, Grace L, Taniguchi, Cullen M, Krishnan, Sunil, Crane, Christopher H, Grassberger, Clemens, Hong, Theodore S, Lin, Steven H, Koong, Albert C, Mohan, Radhe, Koay, Eugene J“…PATIENTS AND METHODS: Patients with HCC treated with definitive RT from 2006 to 2016 were studied. Serial ALCs were graded according to CTCAE v4.0. Overall survival (OS), disease-free survival, and distant metastasis-free survival were analyzed using the Kaplan–Meier method. …”
Publicado 2021
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23178por Raphael, Claire E., Mitchell, Frances, Kanaganayagam, Gajen Sunthar, Liew, Alphonsus C., Di Pietro, Elisa, Vieira, Miguel Silva, Kanapeckaite, Lina, Newsome, Simon, Gregson, John, Owen, Ruth, Hsu, Li-Yueh, Vassiliou, Vassilis, Cooper, Robert, MRCP, Aamir Ali, Ismail, Tevfik F., Wong, Brandon, Sun, Kristi, Gatehouse, Peter, Firmin, David, Cook, Stuart, Frenneaux, Michael, Arai, Andrew, O’Hanlon, Rory, Pennell, Dudley J., Prasad, Sanjay K.“…We assessed the predictive value of cardiovascular magnetic resonance (CMR) for development of HF in HCM in an observational cohort study. METHODS: Serial patients with HCM underwent CMR, including adenosine first-pass perfusion, left atrial (LA) and left ventricular (LV) volumes indexed to body surface area (i) and late gadolinium enhancement (%LGE- as a % of total myocardial mass). …”
Publicado 2021
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23179“…Estimates of the instantaneous R (Wallinga and Teunis method) with a short and standard serial interval were done. WGS were used to determine the populations genomic variation and that underpinned creation of the pathogen genome identity (GENI) score, which was merged with the outbreak curve in four distinct phases. …”
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23180por Lee, Alex Q., Ijiri, Masami, Rodriguez, Ryan, Gandour-Edwards, Regina, Lee, Joyce, Tepper, Clifford G., Li, Yueju, Beckett, Laurel, Lam, Kit, Goodwin, Neal, Satake, Noriko“…The therapeutic efficacy of sunitinib and temsirolimus was tested in a serially-transplanted generation of 27 PE PDX mice. …”
Publicado 2021
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