“…Patients were stratified into either obese (body mass index [BMI] ≥ 30 kg/m(2)) or non-obese (BMI < 30 kg/m(2)) group. Based on serial concentration-time data in serum at steady state, population PK analysis was performed using NONMEM. …”
Enlace del recurso
Enlace del recurso

“…METHODS: Eligible patients were adults ≥ 18 years who were treated with IV fosfomycin 2-4 g every 6-8 hours. Five serial blood samples were collected after the 4(th) dose of fosfomycin and concentrations were measured and modeled by population PK analysis. …”
Enlace del recurso
Enlace del recurso

“…Stock solutions were dissolved in 100% DMSO and frozen at -20(o)C until used. Drugs were serially diluted in cation adjusted Mueller-Hinton broth (CAMHB) (Mabs), CAMHB with 5% OADC (MAC), and 7H9 Broth with 10% OADC (Mtb) in microtiter plates for MIC evaluation in duplicate. …”
Enlace del recurso
Enlace del recurso

“…METHODS: We queried the Centers for Disease Control and Prevention's Wide-Ranging Online Data for Epidemiologic Research (CDC WONDER) database and performed serial cross-sectional analyses of national death certificate data for all-cause mortality with comorbid HIV from 1999 to 2020. …”
Enlace del recurso
Enlace del recurso

“…However, before clinicians recommend antioxidants, randomized controlled trials with sufficient power are necessary to prove the efficacy of antioxidant supplementation in disorders of female reproduction. Serial measurement of oxidative stress biomarkers in longitudinal studies may help delineate the etiology of some of the diosorders in female reproduction such as preeclampsia.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Eleven geometric parameters were examined preoperatively and at least 3, 12 and 24 months after the operation by serial echocardiographic studies and evaluated by paired t test taking the time of surgery as a starting point for remodeling. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…To identify all the expressed genes encoded in the fungal genome, we have analyzed the mycelium and appressorium transcriptomes using massively parallel signature sequencing (MPSS), robust-long serial analysis of gene expression (RL-SAGE) and oligoarray methods. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The tumour markers, CEA, CA 19-9 and CA 195 were serially measured in 16 patients. There was a good correlation with tumour response when all three markers were significantly decreased. …”
Enlace del recurso
Enlace del recurso

“…The most prominent cell type in serially cultured osteosarcomas was fibroblastic in appearance. …”
Enlace del recurso
Enlace del recurso

“…METHODS: Formalin-fixed paraffin-embedded serial sections from 33 supratentorial astrocytomas (5 diffuse fibrillary astrocytomas, WHO grade II; 6 anaplastic astrocytomas, WHO grade III; 22 glioblastomas multiforme, WHO grade IV) were immunostained following microwave pretreatment. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The contributions of the genetic origin of the T cells and the APC were explored. Serial restimulations of the B10.BR TCL with B10.A or (B10.A × B10.BR) F1 splenic antigen presenting cells (APC) during the establishment of TCL markedly reduced both Th1 cytokine production and encephalitogenicity. …”
Enlace del recurso
Enlace del recurso

“…Airway epithelial staining did not co-localise with MUC5AC suggesting that the protein was not produced by goblet cells. Using serial sections stained with neutrophil elastase and CD68 we could not demonstrate co-localisation of SPLUNC1 with either neutrophils or macrophages/monocytes, indicating that these cells were not a source of SPLUNC1 in the airways of CF lungs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The spindle cell outgrowths observed in extended limbal epithelial cultures (LECs) and from deepithelialized limbal tissues were serially passaged using a human corneal epithelial (HCE) medium, which contained epidermal growth factor (EGF) and insulin, and supplemented with fetal bovine serum (FBS). …”
Enlace del recurso
Enlace del recurso

“…Previous studies have used data from several non-serial tissue sections viewed by light microscopy to extrapolate a volume and have assumed that MLBs are random in distribution. …”
Enlace del recurso
Enlace del recurso

“…We evaluated associations of long-term circulating IL-6 levels with CHD risk (defined as nonfatal myocardial infarction [MI] or fatal CHD) in two population-based cohorts, involving serial measurements to enable correction for within-person variability. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…BACKGROUND: Oligoarrays have become an accessible technique for exploring the transcriptome, but it is presently unclear how absolute transcript data from this technique compare to the data achieved with tag-based quantitative techniques, such as massively parallel signature sequencing (MPSS) and serial analysis of gene expression (SAGE). By use of the TransCount method we calculated absolute transcript concentrations from spotted oligoarray intensities, enabling direct comparisons with tag counts obtained with MPSS and SAGE. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…METHODS: The leukemic phenotype of mice deficient for Arid4a with or without haploinsufficiency for Arid4b was investigated by serially monitoring complete blood counts together with microscopic histologic analysis and flow cytometric analysis of bone marrow and spleen from the Arid4a(−/−) mice or Arid4a(−/−)Arid4b(+/−) mice. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Danaparoid was administered as a continuous infusion of 100 anti-Xa-U/hour after a loading dose of 3,500 anti-Xa-U. Serial measurements of anti-Xa activity and prothrombin fragment F1+2 were performed at baseline, at t = 5, 15, and 30 minutes, and at t = 1, 2, 4, 8, 16, and 24 hours after the danaparoid loading dose. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…SuperSAGE, an improved version of the serial analysis of gene expression (SAGE) technique, generating genome-wide, high-quality transcription profiles from any eukaryote, has been employed in the present study. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Promoter activity was measured using serial deletion mutants of DNA fused to the luciferase reporter gene. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso