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  1. 24281
    “…Cardiac and neuroinflammation were serially investigated using whole-body macrophage- and microglia-targeted translocator protein (TSPO) PET at 3 days, 7 days, and 8 weeks. …”
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    Angiotensin-converting enzyme inhibitor treatment early after myocardial infarction attenuates acute cardiac and neuroinflammation without effect on chronic neuroinflammation
  2. 24282
    “…Demographic, clinical, treatment, and laboratory data, including serial samples for viral RNA detection, were extracted from electronic medical records and compared between survivors and non-survivors. …”
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    Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
  3. 24283
    “…Chronic ICI pneumonitis was defined as pneumonitis that persists or worsens with steroid tapering, and necessitates ≥12 weeks of immunosuppression, after ICI discontinuation. Serial chest CT was used to assess radiological features, and tumor response by Response EvaluationCriteria for Solid Tumors V.1.1. …”
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    Chronic immune checkpoint inhibitor pneumonitis
  4. 24284
    “…We then established VCR-resistant RMS and EWS cell lines by exposing cells to serially increasing concentrations of VCR and determining the IC(50). …”
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    Up-regulation of GLI1 in vincristine-resistant rhabdomyosarcoma and Ewing sarcoma
  5. 24285
    “…The effect of the myAID intervention will be assessed using the results of serial Web-based questionnaires and fecal calprotectin at baseline, 2 months, 6 months, and 12 months. …”
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    A Web-Based Decision Aid (myAID) to Enhance Quality of Life, Empowerment, Decision Making, and Disease Control for Patients With Ulcerative Colitis: Protocol for a Cluster Randomized Controlled Trial
  6. 24286
    por Matsukawa, Takashi, Yamamoto, Tomotaka, Honda, Akira, Toya, Takashi, Ishiura, Hiroyuki, Mitsui, Jun, Tanaka, Masaki, Hao, Akihito, Shinohara, Akihito, Ogura, Mizuki, Kataoka, Keisuke, Seo, Sachiko, Kumano, Keiki, Hosoi, Masataka, Narukawa, Kensuke, Yasunaga, Megumi, Maki, Hiroaki, Ichikawa, Motoshi, Nannya, Yasuhito, Imai, Yoichi, Takahashi, Tsuyoshi, Takahashi, Yuji, Nagasako, Yuki, Yasaka, Kyoko, Mano, Kagari Koshi, Matsukawa, Miho Kawabe, Miyagawa, Toji, Hamada, Masashi, Sakuishi, Kaori, Hayashi, Toshihiro, Iwata, Atsushi, Terao, Yasuo, Shimizu, Jun, Goto, Jun, Mori, Harushi, Kunimatsu, Akira, Aoki, Shigeki, Hayashi, Shin, Nakamura, Fumihiko, Arai, Syunya, Momma, Kazunari, Ogata, Katsuhisa, Yoshida, Toshikazu, Abe, Osamu, Inazawa, Johji, Toda, Tatsushi, Kurokawa, Mineo, Tsuji, Shoji
    Publicado 2020
    “…Clinical outcomes of haematopoietic stem cell transplantation were evaluated by the survival rate as well as by serial evaluation of clinical rating scale scores and neurological and MRI findings. …”
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    Clinical efficacy of haematopoietic stem cell transplantation for adult adrenoleukodystrophy
  7. 24287
    “…Furthermore, we also investigated the effect of triclosan exposure in vitro on antibiotic susceptibility and the efflux pump encoding gene expressions of triclosan-susceptible strains via serial passage experiments. RESULTS: Of the 200 E. coli isolates, 2.5% (n = 5) were found to be resistant to triclosan, and multidrug resistance (MDR) and cross-resistance phenotypes were noted for these triclosan-resistant strains. …”
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    The prevalence and mechanism of triclosan resistance in Escherichia coli isolated from urine samples in Wenzhou, China
  8. 24288
    por Laimoud, Mohamed, Alanazi, Mosleh
    Publicado 2020
    “…The objective of this study was to detect the validity of serial measurements of arterial lactate level in differentiating hospital mortality and neurological outcome after VA-ECMO support for adult patients with cardiogenic shock. …”
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    The clinical significance of blood lactate levels in evaluation of adult patients with veno-arterial extracorporeal membrane oxygenation
  9. 24289
    “…HIV and Syphilis test were performed by serial algorithm as per the national guidelines. Trends were assessed for HIV, syphilis and HIV/syphilis by estimating seroprevalence from cross-sectional studies. …”
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    Highlighting a population-based re-emergence of Syphilis infection and assessing associated risk factors among pregnant women in Cameroon: Evidence from the 2009, 2012 and 2017 national sentinel surveillance surveys of HIV and syphilis
  10. 24290
    “…Hence, in this study, we focused on the patients from an isolated area, investigated the epidemiological and clinical characteristics of four serial passages of the virus. METHODS: From January 25 to February 29, 2020, all patient data on the SARS-CoV-2 passages in this isolated area were traced, and the patients were grouped according to the passaging of SARS-CoV-2. …”
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    Epidemiological and clinical based study on four passages of COVID-19 patients: intervention at asymptomatic period contributes to early recovery
  11. 24291
    “…METHODS: BHK-21, Huh-7, RD and differentiated normal human bronchial epithelial (dNHBE) cell cultures were exposed to virus and serial dilutions of test compounds. Independent assessments of antiviral activity were obtained by determining effective concentrations of test compounds required to 1) prevent half-maximal (EC(50)) virus-induced cytopathic effect (CPE) using MTT or neutral red staining and 2) produce virus yield reductions (VYR) by 90% (EC(90)) using standard endpoint dilution CCID(50) assays in Vero 76 cells. …”
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    1265. AT-527, an Oral Purine Nucleotide Prodrug Exhibiting Potent In Vitro Antiviral Activity Against Human Coronaviruses, Including SARS-CoV-2
  12. 24292
    “…Body weights were measured serially for 7 days after dose 1. RESULTS: At 28 days following dose 1, mice receiving TQL1055 had an anti-pertussis toxin IgG GMT of 8492, compared with 2263 in mice receiving QS-21 (p = 0.005). …”
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    1238. The Novel Semisynthetic Saponin Adjuvant TQL1055 Enhances the Antibody Response to Pertussis Vaccine with an Improved Tolerability Profile over QS-21
  13. 24293
    “…Bacterial burden was measured on day 1, 27, 42, 56 and 84 after infection by plating serial dilutions of organ homogenates on nutrient 7H11 and charcoal agar and counting CFUs after 25-30 days incubation at 32°C. …”
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    1635. Oral Delivery of Amikacin-Lipid NanoCrystal Formulations Safely and Effectively Treat Macrolide Resistant Mycobacteria Infections in a Mouse Model of Cystic Fibrosis
  14. 24294
    “…We illustrate how multiplex immunofluorescence (mIF) combined with statistical modeling can be used to precisely estimate dynamic changes in sTIL score, PD-L1 expression, and other immune variables from a single paraffin-embedded slide, thus enabling comprehensive characterization of activity of novel immunotherapy agents. METHODS: Serial tissue was obtained from a recent clinical trial evaluating loco-regional cytokine delivery as a strategy to promote immune cell infiltration and activation in breast tumors. …”
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    Multiplex immunofluorescence to measure dynamic changes in tumor-infiltrating lymphocytes and PD-L1 in early-stage breast cancer
  15. 24295
    “…METHODS: Apixaban was added to the CRRT circuit and serial pre-filter bovine blood samples were collected along with post-filter blood and effluent samples. …”
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    Pharmacokinetics and dialytic clearance of apixaban during in vitro continuous renal replacement therapy
  16. 24296
    “…CONCLUSION: Liraglutide did not enhance exercise tolerance or haemodynamics compared with saline placebo during serial treadmill testing in patients with established obstructive CAD. …”
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    Liraglutide to Improve corONary haemodynamics during Exercise streSS (LIONESS): a double-blind randomised placebo-controlled crossover trial
  17. 24297
    “…Participants followed multimedia instructions provided by the app to complete two 20-meter trials each of walking normally (single task) and walking while performing a serial subtraction dual task (dual task). Gait data were simultaneously collected with the app and gold-standard wearable motion sensors. …”
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    Simple Smartphone-Based Assessment of Gait Characteristics in Parkinson Disease: Validation Study
  18. 24298
    “…CONCLUSION: Our study demonstrates that the efficiency of palbociclib and fulvestrant can be monitored by serial analyses of ctDNA before radiological evaluation and that early ctDNA variation is a prognostic factor of PFS. …”
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    Circulating tumor DNA as a dynamic biomarker of response to palbociclib and fulvestrant in metastatic breast cancer patients
  19. 24299
    “…The clinical data were fitted by the Lyman–Kutcher–Burman (LKB) and Relative Seriality (RS) NTCP models. RESULTS: Of 55 evaluable patients, 19 (35%) had ≥ 20 point increase in xerostomia score, 11 (20%) had ≥ 2 point increase in xerostomia bother score, and 13 (24%) had ≥ 2 point increase in SESoD score. …”
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    NTCP modeling and dose–volume correlations for acute xerostomia and dry eye after whole brain radiation
  20. 24300
    “…Using this assay, we tracked antigen dynamics in serial swab samples from COVID patients hospitalized in ICU and immunocompromised COVID patients. …”
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    Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Dynamics Tracking
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