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  1. 24701
    “…Immunohistochemistry was performed on serial 2.5 μm thick tissue sections from tissue microarray blocks. …”
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    Associations of angiogenesis-related proteins with specific prognostic factors, breast cancer subtypes and survival outcome in early-stage breast cancer patients. A Hellenic Cooperative Oncology Group (HeCOG) trial
  2. 24702
    “…Athletes were followed for a minimum of 24 months with serial clinic visits. RESULTS: The three cohorts included 47 athletes (15%) in Group 1 (mean age: 12.0 + 1.5y), 64 athletes (21%) in Group 2 (mean age: 14.3 + 1.3y), and 195 athletes (64%) in Group 3 (mean age: 16.2 + 1.8y). …”
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    Return to Sport and Re-Operation Rates in Athletes Under the Age of 20 Following Primary Anterior Cruciate Ligament Reconstruction: Risk Profile Comparing Three Patient Groups Predicated Upon Skeletal Age
  3. 24703
    “…The S(P)O(2)/ F(i)O(2) ratio may allow for early real-time rapid identification of ARDS, while decreasing the cost, phlebotomy, blood loss, pain, skin breaks, and vascular punctures associated with serial arterial blood gas measurements.…”
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    Comparison of non-invasive to invasive oxygenation ratios for diagnosing acute respiratory distress syndrome following coronary artery bypass graft surgery: a prospective derivation-validation cohort study
  4. 24704
    “…We used segmented ordinary least-squares (OLS) regression using Newey-West standard errors to accommodate for serial autocorrelation, and adjusted for any potential effect of birth seasonality on our outcomes. …”
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    Effect of Ebola virus disease on maternal and child health services in Guinea: a retrospective observational cohort study
  5. 24705
    “…Subjects also underwent serial blood sampling over 24h on Day 1 and 28 to assess the pharmacokinetic and pharmacodynamic effects of oral 11β-MNTDC, including 24h serum drug concentrations, T, LH and FSH suppression (secondary outcomes). …”
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    SUN-LB042 The Novel Androgen 11β-Methyl-19-Nortestosterone Dodecylcarbonate (11β-MNTDC) Effectively Suppresses Gonadotropins and Testosterone in Healthy Men: A Potential Oral Male Hormonal Contraceptive
  6. 24706
    “…On days 30 and 90 after transplantation, a subset of rats in each group was sacrificed, and uterine tissue was recovered and serially sectioned. Hematoxylin and eosin staining and immunohistochemical staining were then performed. …”
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    Transplantation of human endometrial perivascular cells with elevated CYR61 expression induces angiogenesis and promotes repair of a full-thickness uterine injury in rat
  7. 24707
    “…He received high dose steroids and antibiotics with no improvement. Serial CXR showed rapid progression consistent with diffuse alveolar damage and he died 8 days after hospital admission. …”
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    11. Accelerated UIP: a special challenge
  8. 24708
    “…DESIGN, SETTING, AND PARTICIPANTS: This serial cross-sectional study used US national vital statistics data for years 2000 to 2016 for all US residents older than 15 years. …”
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    Trends in Alcohol-Induced Deaths in the United States, 2000-2016
  9. 24709
    “…The median incubation period was 4·0 days (IQR 2·3–4·3) and the median serial interval was 4·0 days (3·0–5·0). Transmission events were likely to have occurred presymptomatically for one case (possibly five more), at the day of symptom onset for four cases (possibly five more), and the remainder after the day of symptom onset or unknown. …”
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    Investigation of a COVID-19 outbreak in Germany resulting from a single travel-associated primary case: a case series
  10. 24710
    “…Pharmacokinetic analysis, serial PET imaging, and biodistribution were first performed for [(89)Zr]Zr-DFO-trastuzumab ((89)Zr-T) up to 8 days post-injection (p.i.) in JIMT-1 bearing mice. …”
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    A preclinical PET dual-tracer imaging protocol for ER and HER2 phenotyping in breast cancer xenografts
  11. 24711
    “…In a large independent series of serial urine samples from DIAGURO follow-up BC cases (n = 394), the agreement between ddPCR and UroMuTERT was (i) strong (kappa coefficient of 0.87), regardless of urine DNA types (kappa coefficient 0.89 for US cfDNA and 0.85 for UP cellDNA), (ii) the highest for samples with mutant allelic fractions (MAFs) > 2% (kappa coefficient of 0.99) and (iii) only minimal for the samples with the lowest MAFs (< 0.5%; kappa coefficient 0.32). …”
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    Development of Sensitive Droplet Digital PCR Assays for Detecting Urinary TERT Promoter Mutations as Non-Invasive Biomarkers for Detection of Urothelial Cancer
  12. 24712
    “…METHODS: We conducted a PK study of CAZ-AVI among pts with and without CRRT. Serial blood samples were collected at 0 (pre-dose), 2, 4, 6, and 8 hours after CAZ-AVI administration. …”
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    1298. Population Pharmacokinetics of Ceftazidime-avibactam among Critically-ill Patients with and without Receipt of Continuous Renal Replacement Therapy
  13. 24713
    “…Mean 0600-1000 4-hour morning window (M4hMW) and mean 24-hour (M24h) A4, T, and A4/T ratios were analyzed from serial serum samples at baseline and on day 15. Results: Dose-dependent reductions in M4hMW A4 were observed [median (range)] in men, consistent with previously presented data in all subjects:Cohort 1: -21% (-84 to -12%);Cohort 2: -37% (-51% to -23%);Cohort 3: -43% (-85% to +140%);Cohort 4: -62% (-90% to -33%). …”
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    Changes in Adrenal and Gonadal Androgens After 14-Day Treatment With CRF1 Receptor Antagonist, Crinecerfont (NBI-74788), in Men With Classic 21-Hydroxylase Deficiency
  14. 24714
    “…Samples were collected after the first or second COVID-19 vaccination. No serial samples were collected. Seroconversion rates and IgG antibody titres against the receptor-binding domain of the SARS-CoV-2 spike protein were measured. …”
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    Antibody development after COVID-19 vaccination in patients with autoimmune diseases in the Netherlands: a substudy of data from two prospective cohort studies
  15. 24715
    “…Limitations include relatively small sample size, lack of independent external validation, no serial ctDNA testing after surgery, and a relatively short follow-up period. …”
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    Utility of ctDNA in predicting response to neoadjuvant chemoradiotherapy and prognosis assessment in locally advanced rectal cancer: A prospective cohort study
  16. 24716
    “…LDRT was administered at 0.5 Gy or 1.5 Gy x 1 (or sham) 72 hours after IAV challenge. Mice were serially monitored for survival and morbidity (raw lung weight, % weight loss, disease severity index). …”
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    Evaluating the Immunomodulatory Profile and Treatment Efficacy of Whole Lung Low-Dose Radiation Therapy (LDRT) in a Preclinical Model of Severe Viral Pneumonia
  17. 24717
    “…In total, 963 children were serially tested for cytomegalovirus (7186 cytomegalovirus measurements taken; median six tests per child, IQR 2–11). …”
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    Cytomegalovirus acquisition in infancy and the risk of tuberculosis disease in childhood: a longitudinal birth cohort study in Cape Town, South Africa
  18. 24718
    “…After a 12-month baseline observation period (3/2016-2/2017), the SPC surveillance intervention was serially implemented according to stepped wedge assignment over a 36-month intervention period (3/2017-2/2020) until all 12 groups of clusters had received the intervention. …”
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    93. Early Recognition and Response to Increases in Surgical Site Infections (SSI) using Optimized Statistical Process Control (SPC) Charts – the Early 2RIS Trial: A Multicenter Stepped Wedge Cluster Randomized Controlled Trial (RCT)
  19. 24719
    “…BACKGROUND: Measuring SARS-CoV-2 antibody prevalence in spent samples at serial time points can determine seropositivity in a diverse pool of individuals to inform understanding of trends as vaccinations are implemented. …”
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    371. Estimating SARS-CoV-2 Seroprevalence from Spent Blood Samples, January–March 2021
  20. 24720
    “…In this work, the strategy of combining metabolic engineering and adaptive laboratory evolution (ALE) was employed to develop recombinant Z. mobilis strains that can utilize xylose efficiently at high concentrations, and NGS-based genome resequencing and RNA-Seq transcriptomics were performed for strains evolved after serial transfers in different media to understand the impact of xylose and differences among strains with different xylose-utilization capabilities at molecular level. …”
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    Development and characterization of efficient xylose utilization strains of Zymomonas mobilis
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