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  1. 6741
    “…BACKGROUND: Mitochondrial DNA (mtDNA) has been reported to play a critical role in the progression of systemic inflammatory response syndrome (SIRS). The pathophysiology of acute respiratory distress syndrome (ARDS) is mainly attributed to the diffuse injury of alveolar epithelial cells caused by dysregulated inflammation upon direct or indirect insults. …”
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    Prognostic value of plasma mitochondrial DNA in acute respiratory distress syndrome (ARDS): a single-center observational study
  2. 6742
    “…At time of onset, the MLA demonstrated an AUROC of 0.931 (95% CI 0.914, 0.948) and a diagnostic odds ratio (DOR) of 53.105 on a testing dataset, exceeding MEWS (0.725, P < .001; DOR 4.358), SOFA (0.716; P < .001; DOR 3.720), and SIRS (0.655; P < .001; DOR 3.290). For prediction 48 h prior to onset, the MLA achieved an AUROC of 0.827 (95% CI 0.806, 0.848) on a testing dataset. …”
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    Validation of a machine learning algorithm for early severe sepsis prediction: a retrospective study predicting severe sepsis up to 48 h in advance using a diverse dataset from 461 US hospitals
  3. 6743
    “…BACKGROUND: Inpatients with acute decompensated heart failure (ADHF) frequently meet sepsis criteria defined by the systemic inflammatory response syndrome (SIRS). To meet CMS guidelines, they receive a fluid bolus and broad-spectrum antibiotics, like piperacillin/tazobactam (pip/tazo), within 3 hours of presentation. …”
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    193. Adding Insalt to Injury: Evaluating the Consequences of Sepsis Protocols on Patients with Heart Failure
  4. 6744
    “…BACKGROUND: In the early postoperative period after cardiac surgery the heart may be temporarily dysfunctional and prone to arrhythmias due to the phenomenon of myocardial stunning, vasoplegic syndrome, systemic inflammatory response syndrome (SIRS), electrolyte disturbances, operative trauma and myocardial edema. …”
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    Postoperative Cardiac Arrest in Cardiac Surgery–How to Improve the Outcome?
  5. 6745
    “…BACKGROUND: Systemic inflammatory response syndrome (SIRS) after surgery for acute Stanford type A aortic dissection (ATAAD) via cardiopulmonary bypass (CPB) are strongly associated with mortality. …”
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    Efficacy and safety of sivelestat sodium for the treatment of inflammatory response in acute Stanford type A aortic dissection: a retrospective cohort study
  6. 6746
    “…Malaria transmission was modelled using an SIRS-type model, adapted to Bancoumana's data. Environmental factors influenced vector mortality and aggressiveness, as well as length of the gonotrophic cycle. …”
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    Modelling malaria incidence with environmental dependency in a locality of Sudanese savannah area, Mali
  7. 6747
    “…CONCLUSIONS: Serum resistin concentrations are elevated in acute inflammation due to sepsis or systemic inflammatory response syndrome (SIRS). The close correlation with other acute phase proteins suggests a predominant, clinically relevant resistin release from macrophages in ICU patients. …”
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    Serum resistin levels in critically ill patients are associated with inflammation, organ dysfunction and metabolism and may predict survival of non-septic patients
  8. 6748
    “…BACKGROUND: The elevated serum and peritoneal cytokine concentrations responsible for the systemic response syndrome (SIRS) and multiorgan failure in patients with severe acute pancreatitis lead to high morbidity and mortality rates. …”
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    Clinical effects of laparotomy with perioperative continuous peritoneal lavage and postoperative hemofiltration in patients with severe acute pancreatitis
  9. 6749
    por Vallée, Julie, Chauvin, Pierre
    Publicado 2012
    “…METHODS: We used data collected in the SIRS cohort study, which was carried out over a 5-year period (2005–2010) among a representative population living in 50 census blocks in the Paris metropolitan area. …”
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    Investigating the effects of medical density on health-seeking behaviours using a multiscale approach to residential and activity spaces: Results from a prospective cohort study in the Paris metropolitan area, France
  10. 6750
    “…For 204 episodes, written sign-out by the primary team was available. 59% of the fevers were in male patients and the mean age was 59 years. 12% had an organ transplant and 45% qualified as highly immunocompromised. 79% met SIRS criteria, whereas only 3% met qSOFA criteria and 2% required escalation of care. …”
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    Responses to Fever Overnight: Do Residents Choose Wisely?
  11. 6751
    “…Sepsis was defined as per the Centers for Medicare and Medicaid Services (CMS) sepsis-1 mandate: 2 of 4 SIRS criteria + suspected infection. RESULTS: All 130/130 (100%) index hospital admissions had a primary discharge diagnosis of sepsis, out of which only 85/130 (65%) met criteria for sepsis. …”
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    761. Sepsis Readmissions and Coding in Two Community Hospitals
  12. 6752
    “…RESULTS: 260 veterans were included in the final analysis: 96% male, mean age 65 years, mean BMI 29, 84 met SIRS criteria for sepsis, and 55% received at least 48 hours of concomitant vancomycin. …”
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    60. Evaluation of Outcomes Associated with Intermittent Versus Extended Infusion of Piperacillin/tazobactam in Acutely Ill Veterans
  13. 6753
    “…Of the 54 patients with fungemia, 8 patients (15.1%) met criteria for septic shock at the time of positive blood culture, while 81% met SIRS criteria. Of the 4,253 total patients, 0.19% had coexisting fungemia and septic shock. …”
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    1167. Got Micafungin? The Incidence of Fungemia in Patients with Septic Shock
  14. 6754
    “…Twenty-seven (79.41%) of participants met SIRS criteria on presentation, two required intensive care, and two participants met HLH criteria. …”
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    930. Clinical Presentation, Treatment, and Outcomes for People with HIV with Histoplasmosis in Memphis, Tennessee
  15. 6755
    “…The acute systemic inflammatory response syndrome (SIRS) and multiorgan dysfunction (MOD) that occur in large burn injuries may be attributed, in part, to immunosuppressive responses such as decreased lymphocytes. …”
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    Increased oxidative phosphorylation in lymphocytes does not atone for decreased cell numbers after burn injury
  16. 6756
    “…The model may be an optional tool other than qSOFA and SIRS criteria. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s12879-021-06169-6.…”
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    Two-stage prediction model for in-hospital mortality of patients with influenza infection
  17. 6757
    “…Such transient events largely fall into the following four types: (1) solar flares, (2) coronal mass ejections (CMEs) including their interplanetary counterparts ICMEs, (3) solar energetic particle (SEP) events, and (4) stream interaction regions (SIRs) including corotating interaction regions (CIRs). …”
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    Earth-affecting solar transients: a review of progresses in solar cycle 24
  18. 6758
    “…Results: Of the 3,898 total adults, septic patients accounted for 92.8% (3,619 patients) by Sepsis-2 criteria (i.e., SIRS criteria). Using Sepsis-3 criteria, 1,827 (46.9%) patients were diagnosed with early sepsis (i.e., initial qSOFA scores ≥ 2) in EDs and 2,622 (67.3%) with sepsis during hospitalization (i.e., increased SOFA scores of ≥ 2 from ED arrival). …”
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    Is qSOFA Suitable for Early Diagnosis of Sepsis Among Bacteremia Patients in Emergency Departments? Time for a Reappraisal of Sepsis-3 Criteria
  19. 6759
    “…PATIENTS AND METHODS: A total of 128 patients with sepsis, 40 patients with system inflammatory reaction syndrome (SIRS) and 40 healthy subjects were enrolled in the Second People’s Hospital of Hunan Province from September 2019 to September 2020. …”
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    HDL-Associated Lipoproteins: Potential Prognostic Biomarkers for Gram-Negative Sepsis
  20. 6760
    “…METHODS: Within the project Metrology for Stable Isotope Reference Standards (SIRS), seven pure N(2)O isotope RMs have been developed and their (15)N/(14)N, (18)O/(16)O, (17)O/(16)O ratios and (15)N site preference (SP) have been analysed by specialised laboratories against isotope reference materials. …”
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    Isotopically characterised N(2)O reference materials for use as community standards
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