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1por Deegan, Miles“…For the past four and a half years he has overseen the work of the Science Data Processor consortium – see <a href="http://ska-sdp.org/">http://ska-sdp.org/</a> for further details. …”
Publicado 2018
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5por Abad, Maria Alba, Zou, Juan, Medina-Pritchard, Bethan, Nigg, Erich A., Rappsilber, Juri, Santamaria, Anna, Jeyaprakash, A. Arockia“…Perturbing either the Ska3-microtubule interaction or the Ska3-Ska1 interactions negatively influences microtubule binding by the Ska complex in vitro and affects the timely onset of anaphase in cells. …”
Publicado 2016
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7“…Spindle and kinetochore-associated complex subunits 1 (SKA1) is essential for proper chromosome segregation in the mitotic cell cycle. …”
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8por Gaitanos, Thomas N, Santamaria, Anna, Jeyaprakash, A Arockia, Wang, Bin, Conti, Elena, Nigg, Erich A“…Ska1 and Ska2 form a complex at the kinetochore–microtubule (KT–MT) interface and are required for timely progression from metaphase to anaphase. …”
Publicado 2009
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9“…Although human and yeast kinetochores are largely homologous, they track microtubules with the unrelated protein complexes Ska (Ska-C, human) and Dam1 (Dam1-C, yeast). We here uncovered that Ska-C and Dam1-C are both widespread among eukaryotes, but in an exceptionally inverse manner, supporting their functional analogy. …”
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10por Yu, Shoukai“…The spindle and kinetochore-associated complex is composed of three members: SKA1, SKA2, and SKA3. It is necessary for stabilizing spindle microtubules attaching to kinetochore (KT) in the middle stage of mitosis. …”
Publicado 2022
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11por Yamada, Yasutaka, Arai, Takayuki, Kojima, Satoko, Sugawara, Sho, Kato, Mayuko, Okato, Atsushi, Yamazaki, Kazuto, Naya, Yukio, Ichikawa, Tomohiko, Seki, Naohiko“…We focused on spindle and kinetochore-associated proteins, SKA1 and SKA3 and demonstrated direct regulation of SKA1 by miR-455-5p and SKA3 by miR-455-3p in RCC cells. …”
Publicado 2018
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12por Rice, Lisa, Waters, Charlotte E, Eccles, Jennifer, Garside, Helen, Sommer, Paula, Kay, Paul, Blackhall, Fiona H, Zeef, Leo, Telfer, Brian, Stratford, Ian, Clarke, Rob, Singh, Dave, Stevens, Adam, White, Anne, Ray, David W“…We discovered a novel gene, FAM33A, subsequently identified as a SKA1 partner and involved in mitosis, and so renamed Ska2. …”
Publicado 2008
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14por Abad, Maria Alba, Medina, Bethan, Santamaria, Anna, Zou, Juan, Plasberg-Hill, Carla, Madhumalar, Arumugam, Jayachandran, Uma, Redli, Patrick Marc, Rappsilber, Juri, Nigg, Erich A., Jeyaprakash, A. Arockia“…Here we show that the kinetochore-associated Ska complex interacts with tubulin monomers via the carboxy-terminal winged-helix domain of Ska1, providing the structural basis for the ability to bind both straight and curved microtubule structures. …”
Publicado 2014
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15por Chen, Yibing, Zhao, Jingjing, Jiao, Zhihui, Wang, Weiwei, Wang, Dandan, Yu, Xiaohe, Shi, Zhiyong, Ge, Naijian, Pan, Qiuzhong, Xia, Jianchuan, Niu, Wancheng, Zhao, Ruihua, Zhang, Xiaofei, Du, Wei“…BACKGROUND: SKA1, an important mitosis protein, has been indicated in the initiation and progression of several malignancies. …”
Publicado 2018
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16por Wadadekar, Yogesh, Bhattacharya, Dipankar, Datta, Abhirup, Paul, Surajit, Oberoi, Divya“…To deliver the full science potential of the square kilometer array (SKA) telescope, several SKA regional centres (SRCs) will be required to be constructed in different SKA member countries around the world. …”
Publicado 2023
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18por Li, Zhengtian, Huang, Lanying, Li, Jiachen, Yang, Wenkang, Li, Weichao, Long, Qiuzhong, Dai, Xinyu, Wang, Hongtao, Du, Gang“…We then evaluated the prognostic impact of the SKA score on survival and assessed the effect of the SKA score on immunotherapy at the pan-cancer level using multiomics bioinformatic analyses. …”
Publicado 2023
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19por Redli, Patrick M., Gasic, Ivana, Meraldi, Patrick, Nigg, Erich A., Santamaria, Anna“…Here, we show that Ska is not only a substrate of Aurora B, but is also required for Aurora B activity. …”
Publicado 2016
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20“…The spindle- and kinetochore-associated (Ska) complex, a hexamer composed of two copies of Ska1, Ska2 and Ska3, has been implicated in both roles. …”
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