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  1. 16861
    “…Ryan: None. J. Del Rivero: None. S.M. Sadowski: None. N. Nilubol: None. J.G. Verbalis: None. …”
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    FRI355 Hypokalemia-induced Nephrogenic Diabetes Insipidus In A Patient With Medullary Thyroid Carcinoma And Paraneoplastic Cushing’s Syndrome
  2. 16862
    “…In contrast, concentrations of 67 metabolites were significantly higher in viral infections than controls, with SM.C16.0 being the best biomarker (AUC = 0.94). …”
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    Elevated phospholipids and acylcarnitines C4 and C5 in cerebrospinal fluid distinguish viral CNS infections from autoimmune neuroinflammation
  3. 16863
    “…DISCLOSURES: Graham M. Snyder, MD, SM, Infectious Diseases Connect: Advisor/Consultant Alexander Sundermann, DrPH, CIC, FAPIC, OpGen: Honoraria…”
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    742. Strain Replacement of Vancomycin-Resistant Enterococcus faecium over 6 years at a Large Tertiary Care Center
  4. 16864
    “…STUDY FUNDING/COMPETING INTEREST(S): The study was supported by both the Portuguese National Science Foundation (FCT; PEst-C/SAU/LA0001/2011) and the UK Wellcome Trust (Grant #86470). SM was supported by the Infertility Research Trust. …”
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    p,p′-DDE activates CatSper and compromises human sperm function at environmentally relevant concentrations
  5. 16865
    “…Another key target for improving satisfaction is to keep antipsychotic drug treatment at the lowest effective doses, as most side effects are dose-related. REFERENCES: 1. Cotton SM, Lambert M, Schimmelmann BG, Mackinnon A, Gleeson JFM, Berk M, et al. …”
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    S57. TREATMENT SATISFACTION IN ACUTE PHASE PSYCHOSIS: COMPARISON BETWEEN ANTIPSYCHOTIC NAïVE AND PREVIOUSLY MEDICATED PATIENTS
  6. 16866
    “…Data from the National Epidemiologic Survey on Alcohol and Related Conditions showed that individuals with general anxiety disorder and substance use disorder (GAD-SUD) have higher psychiatric comorbidity rates than those without substance use disorder (Alegría AA, Hasin DS, Nunes EV, Liu SM, Davies C, Grant BF, Blanco C. 2010 J. Clin. …”
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    The epigenetic modulation of alcohol/ethanol and cannabis exposure/co-exposure during different stages
  7. 16867
    “…The use of a customized panel for congenital hypopituitarism using single molecule molecular inversion probes sequencing (smMIPS) revealed a c.626G>A transition in GH1 gene, predicted to result in p.R209H mutation. …”
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    SUN-245 Heterozygous GH1 p.R209H Variant within a Large Pedigree May Mimic a Growth Hormone Insensitivity Pattern
  8. 16868
    “…Soil water extract has EC 9.4 ± 4.1 dSm/m (soils: water ratio of 1:2.5, n = 713), contains Na(+) 15.9 ± 7.0 > Ca(2+)7.3 ± 5.0 and Mg(2+) 7.3 ± 3.1 > K (+) 0.30±0.20 cmol(eq)/kg, as well as Cl(–) 15.7 ± 7.3 and SO(4)(2–) 14.6 ± 7.9 > HCO(3)(–) 0.55±0.15 > CO(3)(2)(–)< 0.01 cmol(eq)/kg, and has pH 7.9 ± 0.3 (soils: water ratio of 1:5, n = 21). …”
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    Data on the soilscape and vegetation properties at the key site in the NW Caspian sea coast, Russia
  9. 16869
    “…ABBREVIATIONS: AKT: AKT serine/threonine kinase; BAX: BCL2 associated X, apoptosis regulator; BECN1: beclin 1; ChoPL: choline phospholipid; CHKA: choline kinase alpha; CHPT1: choline phosphotransferase 1; CTCF: corrected total cell fluorescence; CTP: cytidine-5ʹ-triphosphate; DCA: dichloroacetate; DMEM: dulbeccos modified Eagles medium; DMSO: dimethyl sulfoxide; EDTA: ethylenediaminetetraacetic acid; ER: endoplasmic reticulum; GDPD5: glycerophosphodiester phosphodiesterase domain containing 5; GFP: green fluorescent protein; GPC: glycerophosphorylcholine; HBSS: hanks balances salt solution; MAP1LC3/LC3: microtubule associated protein 1 light chain 3; LPCAT1: lysophosphatidylcholine acyltransferase 1; LysoPtdCho: lysophosphatidylcholine; MRS: magnetic resonance spectroscopy; MTORC1: mechanistic target of rapamycin kinase complex 1; PCho: phosphocholine; PCYT: choline phosphate cytidylyltransferase; PLA2: phospholipase A2; PLB: phospholipase B; PLC: phospholipase C; PLD: phospholipase D; PCYT1A: phosphate cytidylyltransferase 1, choline, alpha; PI3K: phosphoinositide-3-kinase; pMAFs: pancreatic mouse adult fibroblasts; PNPLA6: patatin like phospholipase domain containing 6; Pro-Cho: propargylcholine; Pro-ChoPLs: propargylcholine phospholipids; PtdCho: phosphatidylcholine; PtdEth: phosphatidylethanolamine; PtdIns3P: phosphatidylinositol-3-phosphate; RPS6: ribosomal protein S6; SCD: stearoyl-CoA desaturase; SEM: standard error of the mean; SM: sphingomyelin; SMPD1/SMase: sphingomyelin phosphodiesterase 1, acid lysosomal; SGMS: sphingomyelin synthase; WT: wild-type…”
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    De novo phosphatidylcholine synthesis is required for autophagosome membrane formation and maintenance during autophagy
  10. 16870
    “…OBJECTIVE: To assess the safety and efficacy of a novel Wnt pathway modulator, lorecivivint (SM04690), for treating pain and inhibiting structural progression in moderately to severely symptomatic knee osteoarthritis (OA). …”
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    Lorecivivint, a Novel Intraarticular CDC‐like Kinase 2 and Dual‐Specificity Tyrosine Phosphorylation‐Regulated Kinase 1A Inhibitor and Wnt Pathway Modulator for the Treatment of Knee Osteoarthritis: A Phase II Randomized Trial
  11. 16871
    “…Mechanistic studies revealed that miR-214-3p over-expression or Sufu inhibition can promote nuclear accumulation of GLI1 protein in AdSPCs, and the consensus sequence (GACCACCCA) for GLI1 binding within smooth muscle alpha-actin (SMαA) and serum response factor (SRF) gene promoters is required for their respective regulation by miR-214-3p and Sufu. …”
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    miR-214-3p-Sufu-GLI1 is a novel regulatory axis controlling inflammatory smooth muscle cell differentiation from stem cells and neointimal hyperplasia
  12. 16872
    “…The negatively correlated substances included lysoPC [16:1(9Z)], S-(9-hydroxy-PGA1)-glutathione, lysoPC [20:5 (5Z, 8Z, 11Z, 14Z, 17Z)], SM (d18:1/14:0), nicotinamide adenine dinucleotide phosphate, 5,10-methylene-THF, folinic acid, N-lactoyl-glycine and 6-hydroxy-5-methoxyindole glucuronide. …”
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    Untargeted metabolomics characteristics of nonobese nonalcoholic fatty liver disease induced by high-temperature-processed feed in Sprague-Dawley rats
  13. 16873
    “…These consisted of: i) a normally-appearing maturation pathway with altered levels of expression of >1 (CD38, CD5, CD19, CD21, CD24, and/or smIgM) phenotypic marker (57/88 patients; 65%) for a total of 3 distinct CVID patient profiles (group 1: 42/88 patients, 48%; group 2: 8/88, 9%; and group 3: 7/88, 8%) and ii) CVID patients with a clearly altered pre-GC B cell maturation pathway in blood (group 4: 31/88 cases, 35%). …”
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    Dissection of the Pre-Germinal Center B-Cell Maturation Pathway in Common Variable Immunodeficiency Based on Standardized Flow Cytometric EuroFlow Tools
  14. 16874
    “…Subgroup diabetes classification was performed using the self-normalizing neural networks algorithm using clinical parameters (HbA1c, time since diabetes diagnosis, HOMA2-IR, HOMA2-B, and BMI) proposed by Bello-Chavolla et al (https://bit.ly/3jSm1xv). Prevalence was estimated using sample weights. 2-year cycles were used as a continuous variable to evaluate the biannual change (BC) of the overall prevalence of diabetes and subgroups. …”
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    Trends in Diabetes Subgroups and Their Risk for All-Cause, Cardiovascular Disease and Diabetes-Specific Mortality in the US: A Data-Driven Reproducible Machine Learning Approach
  15. 16875
    “…In this report, we describe the development and baseline findings from year 1 of “Accelerating Colorectal Cancer Screening through Implementation Science (ACCSIS) in Appalachia,” a 5-year, National Cancer Institute Cancer Moonshot(SM)-funded multilevel intervention (MLI) project to increase screening in Appalachian Kentucky and Ohio primary care clinics. …”
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    Development of a multilevel intervention to increase colorectal cancer screening in Appalachia
  16. 16876
    por Duchemin, Charlotte, Ramos, Joao P., Stora, Thierry, Ahmed, Essraa, Aubert, Elodie, Audouin, Nadia, Barbero, Ermanno, Barozier, Vincent, Bernardes, Ana-Paula, Bertreix, Philippe, Boscher, Aurore, Bruchertseifer, Frank, Catherall, Richard, Chevallay, Eric, Christodoulou, Pinelopi, Chrysalidis, Katerina, Cocolios, Thomas E., Comte, Jeremie, Crepieux, Bernard, Deschamps, Matthieu, Dockx, Kristof, Dorsival, Alexandre, Fedosseev, Valentin N., Fernier, Pascal, Formento-Cavaier, Robert, El Idrissi, Safouane, Ivanov, Peter, Gadelshin, Vadim M., Gilardoni, Simone, Grenard, Jean-Louis, Haddad, Ferid, Heinke, Reinhard, Juif, Benjamin, Khalid, Umair, Khan, Moazam, Köster, Ulli, Lambert, Laura, Lilli, G., Lunghi, Giacomo, Marsh, Bruce A., Palenzuela, Yisel Martinez, Martins, Renata, Marzari, Stefano, Menaa, Nabil, Michel, Nathalie, Munos, Maxime, Pozzi, Fabio, Riccardi, Francesco, Riegert, Julien, Riggaz, Nicolas, Rinchet, Jean-Yves, Rothe, Sebastian, Russell, Ben, Saury, Christelle, Schneider, Thomas, Stegemann, Simon, Talip, Zeynep, Theis, Christian, Thiboud, Julien, van der Meulen, Nicholas P., van Stenis, Miranda, Vincke, Heinz, Vollaire, Joachim, Vuong, Nhat-Tan, Webster, Benjamin, Wendt, Klaus, Wilkins, Shane G.
    Publicado 2021
    “…Since its commissioning, the CERN-MEDICIS facility has provided its partner institutes with non-conventional medical radionuclides such as Tb-149, Tb-152, Tb-155, Sm-153, Tm-165, Tm-167, Er-169, Yb-175, and Ac-225 with a high specific activity. …”
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    CERN-MEDICIS: A Review Since Commissioning in 2017
  17. 16877
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    Association of Breast Density With Breast Cancer Risk Among Women Aged 65 Years or Older by Age Group and Body Mass Index
  18. 16878
    “…Records containing concomitant HEp-2 IFA and SS-A/Ro tests from Durand Laboratory, Argentina (n = 383) and Fleury Laboratory, Brazil (n = 144,471) were analyzed for associations between HEp-2 IFA patterns and disease-associated autoantibodies (DAA): double-stranded DNA, Scl-70, nucleosome, SS-B/La, Sm, and U1-RNP. A total of 381 samples from Dresden Technical University (TU-Dresden), Germany, were assayed for HEp-2 IFA and DAA. …”
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    Strong Association of the Myriad Discrete Speckled Nuclear Pattern With Anti-SS-A/Ro60 Antibodies: Consensus Experience of Four International Expert Centers
  19. 16879
    “…N.P.J. reports personal fees from Abbott, Guerbet, Myovant Sciences, Vifor Pharma, Roche Diagnostics outside the submitted work; he is also President of the World Endometriosis Society and chair of the trust board. S.M. reports grants and personal fees from AbbVie, and personal fees from Roche outside the submitted work. …”
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    An international terminology for endometriosis, 2021(,)
  20. 16880
    “…N.P.J. reports personal fees from Abbott, Guerbet, Myovant Sciences, Vifor Pharma, Roche Diagnostics, outside the submitted work; he is also President of the World Endometriosis Society and chair of the trust board. S.M. reports grants and personal fees from AbbVie, and personal fees from Roche outside the submitted work. …”
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    Endometriosis classification, staging and reporting systems: a review on the road to a universally accepted endometriosis classification(,)
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