Mostrando 1 - 20 Resultados de 70 Para Buscar '"snipers"', tiempo de consulta: 0.38s Limitar resultados
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    por Brewer, Paul, Ratan, Anmol
    Publicado 2019
    “…We provide a dataset for our research article “Profitability, Efficiency and Inequality in Double Auction Markets with Snipers” [1]. This dataset [2] includes configuration files, raw output data, and replications of calculated metrics for our robot-populated market simulations. …”
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    “…Chimeric small molecules such as Proteolysis Targeting Chimeras (PROTACs) and Specific and Non-genetic IAP-dependent Protein Erasers (SNIPERs), and E3 modulators such as thalidomides, hijack the cellular machinery for ubiquitylation, and the ubiquitylated proteins are subjected to proteasomal degradation. …”
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    “…In this study, we describe an explorative case study on the integration of mental skill training techniques to an advanced sniper course in the Norwegian Armed Forces. We evaluate the impact through triangulation and examine results on the course, perceptions of the participants, and observations from the instructors. …”
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  5. 5
    por Simola, Daniel F, Kim, Junhyong
    Publicado 2011
    “…An implementation of Sniper is freely available at http://kim.bio.upenn.edu/software/sniper.shtml.…”
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    “…In this review, we will present the most relevant advances in the field of SNIPERs and provide our perspective on the opportunities and challenges for SNIPERs to become therapeutic agents.…”
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    “…We previously developed a hybrid small molecule SNIPER (Specific and Nongenetic IAP‐dependent Protein ERaser) against transforming acidic coiled‐coil‐3 (TACC3), SNIPER(TACC3), that induces proteasomal degradation of TACC3 protein. …”
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    “…This article reviews chimeric drugs that decrease the level of specific proteins such as proteolysis targeting chimeric molecules (PROTACs) and specific and nongenetic inhibitor of apoptosis protein (IAP)-dependent protein erasers (SNIPERs), which target proteins for proteasome-mediated degradation. …”
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    “…We evaluated Sniper2L activities at a large number of target sequences and developed DeepSniper, a deep learning model that can predict the activity of Sniper2L. …”
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    “…The levels of 6mA sites pinpointed by 6mA-Sniper are generally increased after Pseudomonas aeruginosa infection, but decreased in strains with the removal of METL-9, the dominant 6mA methyltransferase. …”
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    “…We include a training set for these algorithms based on individual genotypes for 705 samples. SNiPer has the capability to be retrained for lab-specific training sets. …”
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    “…Hence, event‐driven pharmacology‐based approaches, such as proteolysis targeting chimeras (PROTACs) and SNIPERs (specific non‐genetic IAP‐based protein erasers) have been developed. …”
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    por Kyle, Chris, 1974-2013
    Publicado 2014
    “…American sniper.…”
    Libro
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    “…In some cases, fake news was spread, such as the use of snipers at the border of nations to kill wild boars or the possible risks to human health. …”
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    “…Degraders (e.g. PROTACs, SNIPERs, degronimers etc.) are a new modality offering increasing potential both as tools for basic research and therapeutic development. …”
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