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2“…We provide a dataset for our research article “Profitability, Efficiency and Inequality in Double Auction Markets with Snipers” [1]. This dataset [2] includes configuration files, raw output data, and replications of calculated metrics for our robot-populated market simulations. …”
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3“…Chimeric small molecules such as Proteolysis Targeting Chimeras (PROTACs) and Specific and Non-genetic IAP-dependent Protein Erasers (SNIPERs), and E3 modulators such as thalidomides, hijack the cellular machinery for ubiquitylation, and the ubiquitylated proteins are subjected to proteasomal degradation. …”
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4“…In this study, we describe an explorative case study on the integration of mental skill training techniques to an advanced sniper course in the Norwegian Armed Forces. We evaluate the impact through triangulation and examine results on the course, perceptions of the participants, and observations from the instructors. …”
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5“…An implementation of Sniper is freely available at http://kim.bio.upenn.edu/software/sniper.shtml.…”
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7por Wang, Chao, Zhang, Yujing, Shi, Lingyu, Yang, Shanbo, Chang, Jing, Zhong, Yingjie, Li, Qian, Xing, Dongming“…In this review, we will present the most relevant advances in the field of SNIPERs and provide our perspective on the opportunities and challenges for SNIPERs to become therapeutic agents.…”
Publicado 2022
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8por Ohoka, Nobumichi, Nagai, Katsunori, Shibata, Norihito, Hattori, Takayuki, Nara, Hiroshi, Cho, Nobuo, Naito, Mikihiko“…We previously developed a hybrid small molecule SNIPER (Specific and Nongenetic IAP‐dependent Protein ERaser) against transforming acidic coiled‐coil‐3 (TACC3), SNIPER(TACC3), that induces proteasomal degradation of TACC3 protein. …”
Publicado 2017
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9“…This article reviews chimeric drugs that decrease the level of specific proteins such as proteolysis targeting chimeric molecules (PROTACs) and specific and nongenetic inhibitor of apoptosis protein (IAP)-dependent protein erasers (SNIPERs), which target proteins for proteasome-mediated degradation. …”
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10por Kim, Young-hoon, Kim, Nahye, Okafor, Ikenna, Choi, Sungchul, Min, Seonwoo, Lee, Joonsun, Bae, Seung-Min, Choi, Keunwoo, Choi, Janice, Harihar, Vinayak, Kim, Youngho, Kim, Jin-Soo, Kleinstiver, Benjamin P., Lee, Jungjoon K., Ha, Taekjip, Kim, Hyongbum Henry“…We evaluated Sniper2L activities at a large number of target sequences and developed DeepSniper, a deep learning model that can predict the activity of Sniper2L. …”
Publicado 2023
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11por Zhang, Jie, Peng, Qi, Ma, Chengchuan, Wang, Jiaxin, Xiao, Chunfu, Li, Ting, Liu, Xiaoge, Zhou, Liankui, Xu, Xinwei, Zhou, Wei-Zhen, Ding, Wanqiu, An, Ni A., Zhang, Li, Liu, Ying, Li, Chuan-Yun“…The levels of 6mA sites pinpointed by 6mA-Sniper are generally increased after Pseudomonas aeruginosa infection, but decreased in strains with the removal of METL-9, the dominant 6mA methyltransferase. …”
Publicado 2023
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12por Huentelman, Matthew J, Craig, David W, Shieh, Albert D, Corneveaux, Jason J, Hu-Lince, Diane, Pearson, John V, Stephan, Dietrich A“…We include a training set for these algorithms based on individual genotypes for 705 samples. SNiPer has the capability to be retrained for lab-specific training sets. …”
Publicado 2005
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13por Bochicchio, Anna, Jordaan, Sandra, Losasso, Valeria, Chetty, Shivan, Casasnovas Perera, Rodrigo, Ippoliti, Emiliano, Barth, Stefan, Carloni, PaoloEnlace del recurso
Publicado 2017
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14por Mijnes, Jolein, Tiedemann, Janina, Eschenbruch, Julian, Gasthaus, Janina, Bringezu, Sarah, Bauerschlag, Dirk, Maass, Nicolai, Arnold, Norbert, Weimer, Jörg, Anzeneder, Tobias, Fasching, Peter A., Rübner, Matthias, Bruno, Benjamin, Heindrichs, Uwe, Freres, Jennifer, Schulz, Hanna, Hilgers, Ralf-Dieter, Ortiz-Brüchle, Nadina, von Serenyi, Sonja, Knüchel, Ruth, Kloten, Vera, Dahl, Edgar“…CONCLUSIONS: Although liquid biopsy remains challenging, a combination of SPAG6, NKX2-6, ITIH5 and PER1 (SNiPER) provides a promising tool for blood-based breast cancer detection.…”
Publicado 2019
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15“…Hence, event‐driven pharmacology‐based approaches, such as proteolysis targeting chimeras (PROTACs) and SNIPERs (specific non‐genetic IAP‐based protein erasers) have been developed. …”
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16por Mijnes, Jolein, Tiedemann, Janina, Eschenbruch, Julian, Gasthaus, Janina, Bringezu, Sarah, Bauerschlag, Dirk, Maass, Nicolai, Arnold, Norbert, Weimer, Jörg, Anzeneder, Tobias, Fasching, Peter A., Rübner, Matthias, Bruno, Benjamin, Heindrichs, Uwe, Freres, Jennifer, Schulz, Hanna, Hilgers, Ralf-Dieter, Ortiz-Brüchle, Nadina, von Serenyi, Sonja, Knüchel, Ruth, Kloten, Vera, Dahl, EdgarEnlace del recurso
Publicado 2020
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17por Carazo, Fernando, Bértolo, Cristina, Castilla, Carlos, Cendoya, Xabier, Campuzano, Lucía, Serrano, Diego, Gimeno, Marian, Planes, Francisco J., Pio, Ruben, Montuenga, Luis M., Rubio, Angel“…Applying DrugSniper to small cell lung cancer (SCLC), we identified genes extensively explored in SCLC, such as Aurora kinases or epigenetic agents. …”
Publicado 2020
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19por Trotta, Adriana, Marinaro, Mariarosaria, Cavalli, Alessandra, Cordisco, Marco, Piperis, Angela, Buonavoglia, Canio, Corrente, Marialaura“…In some cases, fake news was spread, such as the use of snipers at the border of nations to kill wild boars or the possible risks to human health. …”
Publicado 2022
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20“…Degraders (e.g. PROTACs, SNIPERs, degronimers etc.) are a new modality offering increasing potential both as tools for basic research and therapeutic development. …”
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