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361001por Huoman, Johanna, Martínez-Enguita, David, Olsson, Elin, Ernerudh, Jan, Nilsson, Lennart, Duchén, Karel, Gustafsson, Mika, Jenmalm, Maria C.“…To this end, > 866000 CpG sites (MethylationEPIC 850K array) in cord blood CD4+ T cells were examined in samples from all four study arms (double-treatment: n = 18, single treatments: probiotics n = 16, ω-3 n = 15, and double placebo: n = 14). Statistical and bioinformatic analyses identified treatment-associated differentially methylated CpGs and genes, which were used to identify putatively treatment-induced network modules. …”
Publicado 2021
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361002por Tinland, Aurélie, Loubiere, Sandrine, Cantiello, Matthieu, Boucekine, Mohamed, Girard, Vincent, Taylor, Owen, Auquier, Pascal“…LIMITATIONS: 1) 8.7% (n = 2) people in HF group died before HF intervention but were analyzed in intention-to-treat. 2) No proof of life or death has been found for only 0.6% in HF group (n = 2) but for 9.5% people in TAU group (n = 33) that could be anonymous deaths. 3) Undetermined causes represented 8.7% of deaths in HF group versus 36.4% in TAU group. 4) The small number of events (deaths) in the study population is a limitation for statistical analysis. CONCLUSIONS: Due to important limitations, we cannot conclude on HF effect on mortality, but our results nevertheless confirm that the vulnerability of long-term homeless people with SMI persists after accessing independent housing. …”
Publicado 2021
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361003“…However, PFS rate in ESCC patients with low NLR at baseline (HR = 1.060, 95% CI 0.524–2.146, P = 0.869) or 3 weeks post treatment (HR = 1.293, 95% CI 0.628–2.663, P = 0.459) was comparable with high NLR. And no statistically different was found in PFS rate between low PLR and high PLR at baseline (HR = 0.786, 95% CI 0.389–1.589, P = 0.469), 3 weeks post treatment (HR = 0.767, 95% CI 0.379–1.552, P = 0.452) or 6 weeks post treatment (HR = 1.272, 95% CI 0.624–2.594, P = 0.488) in ESCC patients. …”
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361004por Li, Xiaohe, Shen, Chenguang, Wang, Lifei, Majumder, Sumit, Zhang, Die, Deen, M. Jamal, Li, Yanjie, Qing, Ling, Zhang, Ying, Chen, Chuming, Zou, Rongrong, Lan, Jianfeng, Huang, Ling, Peng, Cheng, Zeng, Lijiao, Liang, Yanhua, Cao, Mengli, Yang, Yang, Yang, Minghui, Tan, Guoyu, Tang, Shenghong, Liu, Lei, Yuan, Jing, Liu, Yingxia“…More than half of the COVID-19 patients revealed abnormal conditions in lung function after 90 days from onset, and the ratio of abnormal lung function did not differ on a statistically significant level between the fibrotic and non-fibrotic groups. …”
Publicado 2021
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361005por Kuruc Poje, Darija, Kifer, Domagoj, Huys, Isabelle, Miranda, Joao, Jenzer, Helena, Miljković, Nenad, Hoppe-Tichy, Torsten, Bochniarz, Marcin, Frontini, Roberto, Schwartz, David G, Vujić-Aleksić, Vesna, Nežić, Lana, Rinaki, Eleni, Tzimis, Leonidas, Green, Kim, Jovanić, Jelena, Carić, Bojana, Mandić, Danijela, Vilić, Katarina, Bochenek, Tomasz, Bačić Vrca, Vesna, Marušić, Srećko“…Analyses were performed using R: a language and environment for statistical computing (v 3.6.3). RESULTS: 6 % of patients reported experiences with drug shortages while hospitalized which led to a deterioration of their health. …”
Publicado 2021
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361006“…P < 0.05 was used to represent a statistically significant difference. RESULTS: A total of 225 cases of unilateral femoral neck fractures were included and followed up for an average of 4.12 ± 0.69 years. …”
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361007por Moazzeni, Seyyed Saeed, Hizomi Arani, Reyhane, Deravi, Niloofar, Hasheminia, Mitra, Khalili, Davood, Azizi, Fereidoun, Hadaegh, Farzad“…The effect of weight loss > 5% was in opposite direction among those older versus younger than 60 years; with suggestive increased risk (not statistically significant) of incident CHD/CVD for the older group. …”
Publicado 2021
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361008por Darteh, Eugene Kofuor Maafo, Abraham, Susanna Aba, Seidu, Abdul-Aziz, Chattu, Vijay Kumar, Yaya, Sanni“…Both descriptive (frequencies and percentages) and inferential analysis (multilevel mixed-effects complementary log–log regression model) were conducted and the statistical significance was set at p < 0.05. RESULTS: The prevalence of knowledge of mother to child transmission of HIV and AIDS during pregnancy, delivery, breastfeeding and at least knowledge of one source are 87.0%, 81.1%, 80.3% and 91.4% respectively. …”
Publicado 2021
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361009por Tuttolomondo, Antonino, Del Cuore, Alessandro, La Malfa, Alessandro, Casuccio, Alessandra, Daidone, Mario, Maida, Carlo Domenico, Di Raimondo, Domenico, Di Chiara, Tiziana, Puleo, Maria Grazia, Norrito, Rosario, Guercio, Giovanni, Pinto, Antonio“…We also reported a negative correlation between the RHI value and HRV indices and the expression of increased parasympathetic activity (RMSDD and HF%) in subjects with diabetic foot and a statistically significant positive correlation with the LF/HF ratio and the expression of the sympathovagal balance. …”
Publicado 2021
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361010por Isaak, Alexander, Luetkens, Julian A., Faron, Anton, Endler, Christoph, Mesropyan, Narine, Katemann, Christoph, Zhang, Shuo, Kupczyk, Patrick, Kuetting, Daniel, Attenberger, Ulrike, Dabir, Darius“…Friedman test, chi-squared test, and Bland-Altman method were used for statistical analysis. RESULTS: Overall IQ score of REACT-CMRA was higher compared to first-pass-CMRA (3.5 ± 0.4 vs. 2.7 ± 0.4, P < 0.001) and did not differ from steady-state-CMRA (3.5 ± 0.4 vs. 3.5 ± 0.6, P = 0.99). …”
Publicado 2021
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361011“…RESULTS: Alcohol consumption was associated with all assessed outcomes in a J-shaped manner relative to current non-drinkers, with a risk reduction that peaked at 7 g/day (relative risk 0.79, 95% confidence interval 0.73–0.85) for all-cause mortality, 8 g/day (0.73, 0.64–0.83) for cardiovascular mortality and 6 g/day (0.50, 0.26–0.96) for cardiovascular events, and remained significant up to 62, 50, and 15 g/day, respectively. No statistically significant elevated risks were found at higher levels of drinking. …”
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361012por Stellato, Marco, Procopio, Giuseppe, De Giorgi, Ugo, Maruzzo, Marco, Bimbatti, Davide, Mennitto, Alessia, Sbrana, Andrea, Roviello, Giandomenico, Casadei, Chiara, Sepe, Pierangela, Pignata, Sandro, Santini, Daniele“…Secondary endpoints were to evaluate Time to treatment failure (TTF) and overall survival (OS) in both groups. All statistical analyses were performed using SPSS software (version 19.00, SPSS, Chicago). …”
Publicado 2021
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361013por Li, Guoju, Xing, Yuhan, Wang, Guolan, Zhang, Jun, Wu, Qin, Ni, Wei, Jiao, Na, Chen, Wenjing, Liu, Qing, Gao, Li, Zhang, Zhenhong, Wang, Yao, Xing, Quansheng“…The interactive effect of maternal pre-pregnancy BMI and age was statistically significant on macrosomia irrespective of parity (nullipara: P(adjusted)=0.0265; multipara: P(adjusted)=0.0356). …”
Publicado 2021
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361014por Li, Shuangyue, Guan, Huai, Zhang, Yan, Li, Sheng, Li, Kaixin, Hu, Shuhai, Zuo, Enjun, Zhang, Cong, Zhang, Xin, Gong, Guanyu, Wang, Ruoyu, Piao, Fengyuan“…The correlation between neurotrophin NGF and TNFα was also investigated. Statistical significance was evaluated using one-way ANOVA and performed using SPSS 13.0. …”
Publicado 2021
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361015por Wang, Xiaowen, Luo, Hongbing, Yao, Enlong, Tang, Renhai, Dong, Wenbin, Liu, Fuyong, Liang, Jun, Li, Huilan, Xiao, Minyang, Zhang, Zuyang, Niu, Jin, Song, Lijun, Fu, Liru, Li, Xuehua, Qian, Shicong, Guo, Qing, Song, Zhizhong“…We assembled municipal-level data about social economic from Yunnan Statistical Yearbook in 2020 and strategy practice information from the self-evaluation system. …”
Publicado 2021
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361016por Tominaga, Naoto, Yonaha, Tomoki, Yamanouchi, Masayuki, Sumi, Hirofumi, Taki, Yasuhiro, Shibagaki, Yugo, Shiizaki, Kazuhiro, Yano, Shozo“…P < 0.05 indicated statistically significant differences. RESULTS: One hundred and six patients were analyzed. …”
Publicado 2021
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361017por Fan, Ying, Nirujogi, Raja S., Garrido, Alicia, Ruiz-Martínez, Javier, Bergareche-Yarza, Alberto, Mondragón-Rezola, Elisabet, Vinagre-Aragón, Ana, Croitoru, Ioana, Gorostidi Pagola, Ana, Paternain Markinez, Laura, Alcalay, Roy, Hickman, Richard A., Düring, Jonas, Gomes, Sara, Pratuseviciute, Neringa, Padmanabhan, Shalini, Valldeoriola, Francesc, Pérez Sisqués, Leticia, Malagelada, Cristina, Ximelis, Teresa, Molina Porcel, Laura, Martí, Maria José, Tolosa, Eduardo, Alessi, Dario R., Sammler, Esther M.“…The effect of the LRRK2 G2019S mutation did not reach statistical significance. Furthermore, we show that LRRK2 phosphorylation at Serine 935 is not a marker for LRRK2 kinase activity in human neutrophils. …”
Publicado 2021
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361018por Murali, Krithika, Dwarte, Tanya M., Nikfarjam, Mehrdad, Tucker, Katherine M., Vaughan, Rhys B., Efthymiou, Marios, Collins, Allison, Spigelman, Allan D., Salmon, Lucinda, Johns, Amber L., Williams, David B., Delatycki, Martin B., John, Thomas, Stoita, Alina“…We audited the genetic investigations offered by multiple Familial Cancer Services who assessed APCSP participants according to national guidelines, local clinical protocol and/or the availability of external research-funded testing, and the subsequent findings. Descriptive statistical analysis was performed using Microsoft Excel. …”
Publicado 2021
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361019por Liefwalker, Daniel F., Ryan, Meital, Wang, Zhichao, Pathak, Khyatiben V., Plaisier, Seema, Shah, Vidhi, Babra, Bobby, Dewson, Gabrielle S., Lai, Ian K., Mosley, Adriane R., Fueger, Patrick T., Casey, Stephanie C., Jiang, Lei, Pirrotte, Patrick, Swaminathan, Srividya, Sears, Rosalie C.“…We utilize preclinical murine models and transgenic primary model of T-ALL to determine the effect of lipogenesis blockade across BCR-ABL-, RAS-, and c-MYC-driven lymphoid malignancies. Statistical significance was calculated using unpaired t-tests and one-way ANOVA. …”
Publicado 2021
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361020por Seguin-Fowler, Rebecca A., Hanson, Karla L., Jilcott Pitts, Stephanie B., Kolodinsky, Jane, Sitaker, Marilyn, Ammerman, Alice S., Marshall, Grace A., Belarmino, Emily H., Garner, Jennifer A., Wang, Weiwei“…RESULTS: No significant net effects on children’s dietary intake, BMI, or physical activity were observed. Statistically significant net improvements were observed after one growing season for caregivers’ cooking attitudes, skills, and self-efficacy; FV intake and skin carotenoid levels; and household food security. …”
Publicado 2021
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