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363221por Rozé, Jean-Christophe, Morel, Baptiste, Lapillonne, Alexandre, Marret, Stéphane, Guellec, Isabelle, Darmaun, Dominique, Bednarek, Nathalie, Moyon, Thomas, Marchand-Martin, Laetitia, Benhammou, Valérie, Pierrat, Véronique, Flamant, Cyril, Gascoin, Géraldine, Mitanchez, Delphine, Cambonie, Gilles, Storme, Laurent, Tosello, Bathélémie, Biran, Valérie, Claris, Olivier, Picaud, Jean-Charles, Favrais, Géraldine, Beuchée, Alain, Loron, Gauthier, Gire, Catherine, Durrmeyer, Xavier, Gressens, Pierre, Saliba, Elie, Ancel, Pierre-Yves“…A confirmatory analysis used neonatal intensive care unit preference for high early amino acid intake as an instrumental variable to account for unmeasured confounding. Statistical analysis was performed from January 15 to May 15, 2021. …”
Publicado 2021
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363222por Levin, Myron J, Ustianowski, Andrew, De Wit, Stéphane, Launay, Odile, Avila, Miles, Seegobin, Seth, Templeton, Alison, Yuan, Yuan, Ambery, Philip, Arends, Rosalinda H, Beavon, Rohini, Near, Karen A, Padilla, Kelly W, Psachoulia, Konstantina, Sharbaugh, Audrey, Streicher, Katie, Pangalos, Menelas N, Esser, Mark T, Gasser, Robert A“…[Image: see text] CONCLUSION: The primary study endpoints were met: a one-time dose of AZD7442 demonstrated statistically significant protection against symptomatic COVID-19 and was well tolerated. …”
Publicado 2021
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363223por Alagbe, Adekunle Emmanuel, Pedroso, Gisele Audrei, Oliveira, Beatriz Benedetti de, Costa, Edivilson de, Maia, Gisélia Aparecida Freire, Piellusch, Bruna Facanali, Albuquerque, Dulcinéia Martins, Schreiber, Angelica Zaninelli, Modena, José Luiz Proença, Jorge, Susan Elisabeth Domingues Costa, Costa, Fernando Ferreira, Sonati, Maria de Fátima, Santos, Magnun Nueldo Nunes“…The survivors (n=257) were those who recovered from the disease and were discharged from the hospital, while the non-survivors (n=63) were those who died in the course of treatment. Statistical analyses were performed using SPSS (version 22). …”
Publicado 2021
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363224por Chiem, Meady, Rauova, Lubica, Diorio, Caroline, McNerney, Kevin O, Bassiri, Hamid, Sullivan, Kathleen, Behrens, Edward M, Teachey, David T., Lambert, Michele P.“…The antibody levels were compared to control samples including samples from adult patients with VITT and HIT. Statistical analyses with ANOVA were performed to evaluate differences. …”
Publicado 2021
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363225por Kucukyurt, Selin, Şahin, Kübra, Yılmaz, Umut, Erçalışkan, Abdülkadir, Özkan Tekin, Tuba, Ortaboz, Damla, Elverdi, Tuğrul, Salihoğlu, Ayşe, Ar, Muhlis Cem, Öngören, Şeniz, Başlar, Zafer, Eskazan, Ahmet Emre“…Although the percentage of patients with advanced-stage disease was higher during the pandemic than that observed in the pre-pandemic period (64% vs. 53.8%), this difference did not reach statistical significance (p=0.384). The median interval between symptom onset to diagnosis was significantly longer during the pandemic than was observed within the pre-pandemic era (16 weeks vs. 8 weeks, p=0.042). …”
Publicado 2021
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363226“…Figure 1, shows EV TF activities, D-dimer and TFPIα levels obtained for Covid-19 samples, with data segregated based on disease severity outcomes. Statistically significant difference versus the Hospitalized group are shown. …”
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363227por Naing, Phyu Thin, Elshakh, Hadya, Elreda, Lauren, Woo, Joon Ha, Karass, Michael, Prudenti, John, Wu, Alan“…Covariates included in analysis were hypertension, diabetes, hyperlipidemia, cardiac history, and use of antiplatelet and anticoagulant medications prior to admission. Statistical analysis was done using R version 4.0.2. …”
Publicado 2021
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363228por Lee, Yi, Jehangir, Qasim, Li, Pin, Lin, Chun-Hui, Sule, Anupam A, Krishnamoorthy, Geetha, Goodman, Judie R, Halabi, Abdul, Patel, Kiritkumar, Wang, Dee Dee, Poisson, Laila, Nair, Girish B“…Sensitivity and specificity with different cut-offs of CHA (2)DS (2)-VASc scores were calculated. All statistical tests were 2-sided with an α (significance) level of 0.05. …”
Publicado 2021
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363229“…In addition, longer apheresis time was associated with more cycles of lenalidomide containing regimen, which neared statistical significance (R (2) = 0.0624, p = 0.0658, Fig 4). …”
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363230por Adamkiewicz, Tom, Mubasher, Mohamed, Omole, Folashade, Echols, Melvin R., Payne, Jason, Leak-Johnson, Tennille, Morgan-Billingslea, Jan, Pines, Kathy, Sundal, Deborah A., Krebs, Shira, Chang, Eric, Afranie-Sakyi, Jennifer A, Flenaugh, Eric, Volcy, Judith, Garcia, Marlene, Tewolde, Teclemichael, Driss, Adel, Gbinigie, Olusola, Evans, Chad, Harvey, Marques, Alema-Mensah, Ernest, Bryan, Dennis, Majett, Charlye D., Taylor, Herman Alfred“…. > 40 years), sex at birth (females vs. males) and obesity (SAS version 9.4 was used for statistical analyses and overall significance level was set at 0.05). …”
Publicado 2021
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363231por Sharma, Dr. Neha, Jain, Dr. Hasmukh, Muthuluri, Dr. Hemanth, Bonda, Dr. Avinash, Sengar, Dr. Manju, Thorat, Dr. Jayashree, Nayak, Dr. Lingaraj, Bagal, Dr. Bhausaheb“…As the risk of covid related complications increases from mild to severe, almost 50% of the patients are ready to accept ≥ 20% risk of relapse to receive lesser intensity chemotherapy (table 4). There was a statistically significant disagreement between physician and patient responses at 5%, 20%, 30% and 40% risk of covid related complications to receive full intensity therapy. …”
Publicado 2021
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363232por Caocci, Giovanni, Mulas, Olga, Mantovani, Daniela, Costa, Alessandro, Galizia, Andrea, Barabino, Luca, Greco, Marianna, Murru, Roberta, La Nasa, Giorgio“…Given the potent anti-inflammatory properties of ruxolitinib against immunocompetent cells, we previously reported a lower but non-statistically absolute IgG anti-Spike humoral response in vaccinated MF patients treated with ruxolitinib. …”
Publicado 2021
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363233por Funk, Anna L., Florin, Todd A., Kuppermann, Nathan, Tancredi, Daniel J., Xie, Jianling, Kim, Kelly, Neuman, Mark I., Ambroggio, Lilliam, Plint, Amy C., Mintegi, Santiago, Klassen, Terry P., Salvadori, Marina I., Malley, Richard, Payne, Daniel C., Simon, Norma-Jean, Yock-Corrales, Adriana, Nebhrajani, Jasmine R., Chaudhari, Pradip P., Breslin, Kristen A., Finkelstein, Yaron, Campos, Carmen, Bergmann, Kelly R., Bhatt, Maala, Ahmad, Fahd A., Gardiner, Michael A., Avva, Usha R., Shah, Nipam P., Sartori, Laura F., Sabhaney, Vikram J., Caperell, Kerry, Navanandan, Nidhya, Borland, Meredith L., Morris, Claudia R., Gangoiti, Iker, Pavlicich, Viviana, Kannikeswaran, Nirupama, Lunoe, Maren M., Rino, Pedro B., Kam, April J., Cherry, Jonathan C., Rogers, Alexander J., Chong, Shu-Ling, Palumbo, Laura, Angelats, Carlos M., Morrison, Andrea K., Kwok, Maria Y., Becker, Sarah M., Dixon, Andrew C., Poonai, Naveen, Eckerle, Michelle, Wassem, Muhammad, Dalziel, Stuart R., Freedman, Stephen B.“…Participants were youths aged younger than 18 years who were tested for SARS-CoV-2 infection at one of 41 EDs across 10 countries including Argentina, Australia, Canada, Costa Rica, Italy, New Zealand, Paraguay, Singapore, Spain, and the United States. Statistical analysis was performed from September to October 2021. …”
Publicado 2022
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363234por Shi, Huifeng, Chen, Lian, Wang, Yuanyuan, Sun, Mengxing, Guo, Yijie, Ma, Shang, Wang, Xiaoli, Jiang, Hai, Wang, Xiaoxia, Lu, Jie, Ge, Lin, Dong, Shu, Zhuang, Yu, Zhao, Yangyu, Wei, Yuan, Ma, Xudong, Qiao, Jie“…EXPOSURES: Anemia of varying severity during pregnancy was identified from daily standardized electronic inpatient discharge records using corresponding codes of the International Statistical Classification of Diseases and Related Health Problems, Tenth Revision. …”
Publicado 2022
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363235por Stewart, Jenell, Krows, Meighan L., Schaafsma, Torin T., Heller, Kate B., Brown, Elizabeth R., Boonyaratanakornit, Jim, Brown, Clare E., Leingang, Hannah, Liou, Caroline, Bershteyn, Anna, Schwartz, Mark D., Agrawal, Vaidehi, Friedman-Klabanoff, DeAnna, Eustace, Stephen, Stankiewicz Karita, Helen C., Paasche-Orlow, Michael K., Kissinger, Patricia, Hosek, Sybil G., Chu, Helen Y., Celum, Connie, Baeten, Jared M., Wald, Anna, Johnston, Christine, Barnabas, Ruane V.“…Participant demographics and geographical location data from remote trials were pooled and compared with those of the clinic-based study. Statistical comparison of demographic data was limited to participants with COVID infections (ie, those in the remotely conducted Early Treatment Study vs those in the clinic-based study) to improve accuracy of comparison given that the Hydroxychloroquine COVID-19 PEP Trial enrolled participants with COVID-19 exposures and thus had different enrollment criteria. …”
Publicado 2022
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363236“…CONCLUSIONS: Treatment of severe COVID-19 pneumonia, Patients who were mechanically ventilated with methylprednisolone infusion 2 mg/kg/day for 10 days versus dexamethasone 6 mg for 10 days showed a statistically significant improvement in the MV days and length of stay in the intensive care unit, together with the overall mortality and severity inflammatory markers of cytokine storm c-reactive protein (CRP), D-dimer, ferritin, LDH, and N:L ratio.…”
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363237por Zondervan, Krina T, Missmer, Stacey, Abrao, Mauricio S, Einarsson, Jon I, Horne, Andrew W, Johnson, Neil P, Lee, Ted T M, Petrozza, John, Tomassetti, Carla, Vermeulen, Nathalie, Grimbizis, Grigoris, De Wilde, Rudy Leon“…Data were analysed to detect statistically significant differences among user groups. …”
Publicado 2022
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363238por Chiuppesi, Flavia, Zaia, John A, Frankel, Paul H, Stan, Rodica, Drake, Jennifer, Williams, Brenda, Acosta, Anne Marie, Francis, Karyn, Taplitz, Randy A, Dickter, Janet K, Dadwal, Sanjeet, Puing, Alfredo G, Nanayakkara, Deepa D, Ash, Patricia, Cui, Yujie, Contreras, Heidi, La Rosa, Corinna, Tiemann, Katrin, Park, Yoonsuh, Medina, Joybelle, Iniguez, Angelina, Zhou, Qiao, Karpinski, Veronica, Johnson, Daisy, Faircloth, Katelyn, Kaltcheva, Teadora, Nguyen, Jenny, Kha, Mindy, Nguyen, Vu H, Francisco, Sandra Ortega, Grifoni, Alba, Wong, Angela, Sette, Alessandro, Wussow, Felix, Diamond, Don J“…In the open-label cohort, 1·0 × 10(7) plaque-forming units (PFU; low dose), 1·0 × 10(8) PFU (medium dose), and 2·5 × 10(8) PFU (high dose) of COH04S1 were administered by intramuscular injection on day 0 and 28 to sentinel participants using a queue-based statistical design to limit risk. In a randomised dose expansion cohort, additional participants were randomly assigned (3:3:1), using block size of seven, to receive two placebo vaccines (placebo group), one low-dose COH04S1 and one placebo vaccine (low-dose COH04S1 plus placebo group), or two low-dose COH04S1 vaccines (low-dose COH04S1 group). …”
Publicado 2022
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363239por Trommer, Maike, Adams, Anne, Celik, Eren, Fan, Jiaqi, Funken, Dominik, Herter, Jan M., Linde, Philipp, Morgenthaler, Janis, Wegen, Simone, Mauch, Cornelia, Franklin, Cindy, Galldiks, Norbert, Werner, Jan-Michael, Kocher, Martin, Rueß, Daniel, Ruge, Maximilian, Meißner, Anna-Katharina, Baues, Christian, Marnitz, Simone“…Other toxicities, including radionecrosis, were not statistically different in both groups. The concurrent application of RT and ICI, the ECOG-PS, cancer type, and PTV had an independently prognostic impact on OS. …”
Publicado 2022
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363240por Morenas-Rodríguez, Estrella, Li, Yan, Nuscher, Brigitte, Franzmeier, Nicolai, Xiong, Chengjie, Suárez-Calvet, Marc, Fagan, Anne M, Schultz, Stephanie, Gordon, Brian A, Benzinger, Tammie L S, Hassenstab, Jason, McDade, Eric, Feederle, Regina, Karch, Celeste M, Schlepckow, Kai, Morris, John C, Kleinberger, Gernot, Nellgard, Bengt, Vöglein, Jonathan, Blennow, Kaj, Zetterberg, Henrik, Ewers, Michael, Jucker, Mathias, Levin, Johannes, Bateman, Randall J, Haass, Christian“…Cognition was measured using a validated cognitive composite (including DIAN word list test, logical memory delayed recall, digit symbol coding test [total score], and minimental status examination). We based our statistical analysis on univariate and bivariate linear mixed effects models. …”
Publicado 2022
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