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69121por Shideler, Blynn L., Bulea, Thomas C., Chen, Ji, Stanley, Christopher J., Gravunder, Andrew J., Damiano, Diane L.“…While surface NMES has been shown to successfully improve foot drop in CP and stroke, correction of more complex gait abnormalities in CP such as flexed knee (crouch) gait remains challenging due to the level of stimulation needed for the quadriceps muscles that must be balanced with patient tolerability and the ability to deliver NMES assistance at precise times within a gait cycle. …”
Publicado 2020
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69122por Zaccardi, Francesco, Ling, Suping, Lawson, Claire, Davies, Melanie J., Khunti, Kamlesh“…Results were consistent in models further adjusted for medications and comorbidities (myocardial infarction, stroke, peripheral artery disease, heart failure, atrial fibrillation, cancer), with sulfonylurea and insulin associated with increased mortality rates (from cause-specific hazard ratio of 1.06 [95% CI 0.99, 1.14] for cancer death with use of sulfonylurea to 1.42 [1.29, 1.56] for cardiovascular death with use of insulin). …”
Publicado 2020
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69123por McGuire, Darren K., Shih, Weichung J., Cosentino, Francesco, Charbonnel, Bernard, Cherney, David Z. I., Dagogo-Jack, Samuel, Pratley, Richard, Greenberg, Michelle, Wang, Shuai, Huyck, Susan, Gantz, Ira, Terra, Steven G., Masiukiewicz, Urszula, Cannon, Christopher P.“…MAIN OUTCOMES AND MEASURES: Outcomes included time to the first event of (1) the composite of major adverse CV events of myocardial infarction, stroke, or CV death, and each component, (2) the composite of hospitalization for heart failure (HHF) or CV death (HHF/CV death) and each component, and (3) kidney composite outcomes. …”
Publicado 2020
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69124por Peters, Christian D., Kjaergaard, Krista D., Christensen, Kent L., Bibby, Bo M., Jespersen, Bente, Jensen, Jens D.“…Increase in TnT over time (ΔTnT = 12-months-baseline) was significantly associated with increase in left ventricular (LV) mass and NT-proBNP and decrease in LV ejection fraction and late intradialytic stroke volume. ΔTnT was not significantly associated with admissions, CV or intradialytic hypotensive events during follow-up. …”
Publicado 2020
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69125“…Merkel and co-workers reported a high occurrence of pulmonary embolism (PE) and deep venous thrombosis (DVT) among GPA patients included in a randomized therapeutic trial (WeCLOT study) (1) .FAURSCHOU et al. reported that GPA was associated with a much lower relative risk of stroke than of pulmonary embolism and deep venous thrombosis; the risk of venous thromboembolic events among GPA patients was increased during early as well as late follow up periods. …”
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69126por Dagenais, Gilles R., Rydén, Lars, Leiter, Lawrence A., Lakshmanan, Mark, Dyal, Leanne, Probstfield, Jeffrey L., Atisso, Charles Messan, Shaw, Jonathan E., Conget, Ignacio, Cushman, William C., Lopez-Jaramillo, Patricio, Lanas, Fernando, Munoz, Ernesto German Cordona, Pirags, Valdis, Pogosova, Nana, Basile, Jan, Sheu, Wayne H. H., Temelkova-Kurktschiev, Theodora, Raubenheimer, Peter J., Keltai, Matyas, Hall, Stephanie, Pais, Prem, Colhoun, Helen M., Riddle, Matthew C., Gerstein, Hertzel C.“…BACKGROUND: The Researching cardiovascular Events with a Weekly INcretin in Diabetes (REWIND) double blind randomized trial demonstrated that weekly subcutaneous dulaglutide 1.5 mg, a glucagon like peptide-1 receptor agonist, versus matched placebo reduced the first outcome of major adverse cardiovascular event (MACE), cardiovascular death, nonfatal myocardial infarction or nonfatal stroke (594 versus 663 events) in 9901 persons with type 2 diabetes and either chronic cardiovascular disease or risk factors, and followed during 5.4 years. …”
Publicado 2020
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69127por Sargurupremraj, Muralidharan, Suzuki, Hideaki, Jian, Xueqiu, Sarnowski, Chloé, Evans, Tavia E., Bis, Joshua C., Eiriksdottir, Gudny, Sakaue, Saori, Terzikhan, Natalie, Habes, Mohamad, Zhao, Wei, Armstrong, Nicola J., Hofer, Edith, Yanek, Lisa R., Hagenaars, Saskia P., Kumar, Rajan B., van den Akker, Erik B., McWhirter, Rebekah E., Trompet, Stella, Mishra, Aniket, Saba, Yasaman, Satizabal, Claudia L., Beaudet, Gregory, Petit, Laurent, Tsuchida, Ami, Zago, Laure, Schilling, Sabrina, Sigurdsson, Sigurdur, Gottesman, Rebecca F., Lewis, Cora E., Aggarwal, Neelum T., Lopez, Oscar L., Smith, Jennifer A., Valdés Hernández, Maria C., van der Grond, Jeroen, Wright, Margaret J., Knol, Maria J., Dörr, Marcus, Thomson, Russell J., Bordes, Constance, Le Grand, Quentin, Duperron, Marie-Gabrielle, Smith, Albert V., Knopman, David S., Schreiner, Pamela J., Evans, Denis A., Rotter, Jerome I., Beiser, Alexa S., Maniega, Susana Muñoz, Beekman, Marian, Trollor, Julian, Stott, David J., Vernooij, Meike W., Wittfeld, Katharina, Niessen, Wiro J., Soumaré, Aicha, Boerwinkle, Eric, Sidney, Stephen, Turner, Stephen T., Davies, Gail, Thalamuthu, Anbupalam, Völker, Uwe, van Buchem, Mark A., Bryan, R. Nick, Dupuis, Josée, Bastin, Mark E., Ames, David, Teumer, Alexander, Amouyel, Philippe, Kwok, John B., Bülow, Robin, Deary, Ian J., Schofield, Peter R., Brodaty, Henry, Jiang, Jiyang, Tabara, Yasuharu, Setoh, Kazuya, Miyamoto, Susumu, Yoshida, Kazumichi, Nagata, Manabu, Kamatani, Yoichiro, Matsuda, Fumihiko, Psaty, Bruce M., Bennett, David A., De Jager, Philip L., Mosley, Thomas H., Sachdev, Perminder S., Schmidt, Reinhold, Warren, Helen R., Evangelou, Evangelos, Trégouët, David-Alexandre, Ikram, Mohammad A., Wen, Wei, DeCarli, Charles, Srikanth, Velandai K., Jukema, J. Wouter, Slagboom, Eline P., Kardia, Sharon L. R., Okada, Yukinori, Mazoyer, Bernard, Wardlaw, Joanna M., Nyquist, Paul A., Mather, Karen A., Grabe, Hans J., Schmidt, Helena, Van Duijn, Cornelia M., Gudnason, Vilmundur, Longstreth, William T., Launer, Lenore J., Lathrop, Mark, Seshadri, Sudha, Tzourio, Christophe, Adams, Hieab H., Matthews, Paul M., Fornage, Myriam, Debette, Stéphanie“…Mendelian randomization suggested causal association of increasing WMH-volume with stroke, Alzheimer-type dementia, and of increasing blood pressure (BP) with larger WMH-volume, notably also in persons without clinical hypertension. …”
Publicado 2020
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69128por Liang, Zhao-Hui, Gu, Jian-Juan, Yu, Wen-Xiu, Guan, Yun-Qian, Khater, Mostafa, Li, Xiao-Bo“…BACKGROUND: Both bone marrow mesenchymal stem cell (BM-MSC) and transforming growth factor-β1 (TGF-β1) have a strong anti-inflammatory capacity in stroke. But their relationship has not been well addressed. …”
Publicado 2020
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69129por Nozari, Younes, Geraiely, Babak, Alipasandi, Kian, Mortazavi, Seyedeh Hamideh, Omidi, Negar, Aghajani, Hassan, Amirzadegan, Alireza, Pourhoseini, Hamidreza, Salarifar, Mojtaba, Alidoosti, Mohammad, Haji-Zeinali, Ali-Mohammad, Nematipour, Ebrahim, Nomali, Mahin“…The primary outcome was in-hospital MACCEs, which was a composite index consisting of cardiac death, revascularization (ie, target vessel revascularization/target lesion revascularization), myocardial infarction, and stroke. It was compared at different levels of time to treatment (ie, symptom-to-door and door-to-balloon time <90 and ≥90 minutes, and symptom-to-balloon time <180 and ≥180 minutes). …”
Publicado 2020
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69130“…The primary endpoints were all-cause mortality and serious adverse events, and the secondary endpoints were cardiovascular mortality, non-fatal myocardial infarction, non-fatal stroke, hypoglycemia, and changes in glycated hemoglobin A1c (HbA1c), body weight, fasting plasma glucose, blood pressure, high-density lipoprotein cholesterol, and low-density lipoprotein cholesterol. …”
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69131por Piroth, Lionel, Cottenet, Jonathan, Mariet, Anne-Sophie, Bonniaud, Philippe, Blot, Mathieu, Tubert-Bitter, Pascale, Quantin, Catherine“…Patients admitted to hospital with COVID-19 more frequently developed acute respiratory failure, pulmonary embolism, septic shock, or haemorrhagic stroke than patients with influenza, but less frequently developed myocardial infarction or atrial fibrillation. …”
Publicado 2021
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69132por Xian, Ying, Zhang, Shuaiqi, Inohara, Taku, Grau-Sepulveda, Maria, Matsouaka, Roland A., Peterson, Eric D., Piccini, Jonathan P., Smith, Eric E., Sheth, Kevin N., Bhatt, Deepak L., Fonarow, Gregg C., Schwamm, Lee H.“…DESIGN, SETTING, AND PARTICIPANTS: This is a cohort study of 219 701 patients with nontraumatic ICH admitted to 1870 hospitals in the Get With The Guidelines–Stroke registry between October 2013 and May 2018. …”
Publicado 2021
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69133por Song, Youhyun, Choi, Ja-Eun, Kwon, Yu-Jin, Chang, Hyuk-Jae, Kim, Jung Oh, Park, Da-Hyun, Park, Jae-Min, Kim, Seong-Jin, Lee, Ji Won, Hong, Kyung-Won“…KoGES_HEXA is a population-based prospective cohort of 173,357 urban Korean adults that had health examinations at medical centers. 42,393 participants (16,309 HTN; 5,314 DM; 20,770 DL) were analyzed, and each metabolic disease group was divided into three CVD case-controls: coronary artery disease (CAD), ischemic stroke (IS), and cardio-cerebrovascular disease (CCD). …”
Publicado 2021
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69134“…Fluid responders, compared to nonresponders, had a significantly higher stroke volume variation (SVV) before fluid bolus (24.1 ± 5.2% vs. 18.2 ± 3.5%, p < 0.001) and a higher reduction in SVV after fluid bolus (10.0 ± 2.8% vs. 6.0 ± 4.5%, p = 0.006), higher lactate clearance (p = 0.03) and lower vasoactive-inotropic score (p = 0.04) at 6 hours, higher percentage of clinical shock resolution at 6 (p = 0.01) and 12 hours (p = 0.01), and lesser mortality (p = 0.002). …”
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69135por Li, Chao, Chen, Kangyu, Cornelius, Victoria, Tomeny, Ewan, Wang, Yang, Yang, Xiaowei, Yuan, Xiaodan, Qin, Rui, Yu, Dahai, Wu, Zhenqiang, Wang, Duolao, Chen, Tao“…Estimated reductions of 0.069 (95% CI −0.28, 0.42) million myocardial infarction cases and 0.36 (95% CI −0.10, 0.82) million stroke cases were not statistically significant. Furthermore, over a lifetime, moving from standard to intensive treatment increased the mean QALYs from 9.51 to 9.87 (an increment of 0.38 [95% CI 0.13 to 0.71]), at a cost of Int$10,997 per QALY gained. …”
Publicado 2021
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69136por Dong, Mingjie, Zhou, Yu, Li, Jianfeng, Rong, Xi, Fan, Wenpei, Zhou, Xiaodong, Kong, Yuan“…However, it is particularly susceptible to musculoskeletal and neurological injuries, especially neurological injuries such as drop foot following stroke. An important factor in ankle dysfunction is damage to the central nervous system (CNS). …”
Publicado 2021
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69137por Gabler, Maximilian, Picker, Nils, Geier, Silke, Ley, Ludwin, Aberle, Jens, Lehrke, Michael, Martin, Stephan, Riedl, Matthias, Wilke, Thomas“…METHODS: In this retrospective German claims data analysis (AOK PLUS dataset), patients with T2DM with an incident diagnosis (index date) of ischemic stroke, myocardial infarction, heart failure or coronary artery disease were observed for 12 months between 1 January 2014 and 31 December 2017. …”
Publicado 2021
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69138por Takeji, Yasuaki, Shiomi, Hiroki, Morimoto, Takeshi, Yoshikawa, Yusuke, Taniguchi, Ryoji, Mutsumura-Nakano, Yukiko, Yamamoto, Ko, Yamaji, Kyohei, Tazaki, Junichi, Kato, Eri Toda, Watanabe, Hirotoshi, Yamamoto, Erika, Yamashita, Yugo, Fuki, Masayuki, Suwa, Satoru, Inoko, Moriaki, Takeda, Teruki, Shirotani, Manabu, Ehara, Natsuhiko, Ishii, Katsuhisa, Inada, Tsukasa, Tamura, Toshihiro, Onodera, Tomoya, Shinoda, Eiji, Yamamoto, Takashi, Watanabe, Hiroki, Yaku, Hidenori, Nakatsuma, Kenji, Sakamoto, Hiroki, Ando, Kenji, Soga, Yoshiharu, Furukawa, Yutaka, Sato, Yukihito, Nakagawa, Yoshihisa, Kadota, Kazushige, Komiya, Tatsuhiko, Minatoya, Kenji, Kimura, Takeshi“…The secondary outcomes were cardiovascular death, cardiac death, sudden cardiac death, non-cardiovascular death, non-cardiac death, myocardial infarction, definite stent thrombosis, stroke, hospitalisation for heart failure, major bleeding, target vessel revascularisation, ischaemia-driven target vessel revascularisation, any coronary revascularisation and any ischaemia-driven coronary revascularisation. …”
Publicado 2021
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69139“…Cardiac functional parameters such as fractional shortening (FS), ejection fraction (EF) and stroke volume (SV) were respectively decreased by 27.6%, 21.02% and 21.20% compared to the vehicle treated group (All, p < 0.05, ANOVA). …”
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69140por Garcia, Santiago, Dehghani, Payam, Grines, Cindy, Davidson, Laura, Nayak, Keshav R., Saw, Jacqueline, Waksman, Ron, Blair, John, Akshay, Bagai, Garberich, Ross, Schmidt, Christian, Ly, Hung Q., Sharkey, Scott, Mercado, Nestor, Alfonso, Carlos E., Misumida, Naoki, Acharya, Deepak, Madan, Mina, Hafiz, Abdul Moiz, Javed, Nosheen, Shavadia, Jay, Stone, Jay, Alraies, M. Chadi, Htun, Wah, Downey, William, Bergmark, Brian A., Ebinger, Jospeh, Alyousef, Tareq, Khalili, Houman, Hwang, Chao-Wei, Purow, Joshua, Llanos, Alexander, McGrath, Brent, Tannenbaum, Mark, Resar, Jon, Bagur, Rodrigo, Cox-Alomar, Pedro, Stefanescu Schmidt, Ada C., Cilia, Lindsey A., Jaffer, Farouc A., Gharacholou, Michael, Salinger, Michael, Case, Brian, Kabour, Ameer, Dai, Xuming, Elkhateeb, Osama, Kobayashi, Taisei, Kim, Hahn-Ho, Roumia, Mazen, Aguirre, Frank V., Rade, Jeffrey, Chong, Aun-Yeong, Hall, Hurst M., Amlani, Shy, Bagherli, Alireza, Patel, Rajan A.G., Wood, David A., Welt, Frederick G., Giri, Jay, Mahmud, Ehtisham, Henry, Timothy D.“…The primary outcome was a composite of in-hospital death, stroke, recurrent myocardial infarction, or repeat unplanned revascularization. …”
Publicado 2021
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