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  1. 69221
    “…The Atherosclerotic Cardiovascular Disease (ASCVD) score was calculated to estimate 10-year risk of cardiovascular disease or stroke and the diabetes lifetime-perspective prediction (DIAL) score was calculated to estimate years free of cardiovascular disease. …”
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    Eliminating exogenous insulin therapy in patients with type 2 diabetes by duodenal ablation and GLP-1RA decreases risk scores for cardiovascular events
  2. 69222
    “…Events were defined as myocardial infarction, coronary revascularization, stroke or death. A total of 649 ECG features, consisting of measurements such as amplitude and interval measurements from all deflections in the ECG waveform (53 per lead and 13 overall) were automatically extracted using a clinical software (GE Muse™ Cardiology Information System, GE Healthcare). …”
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    Machine learning derived ECG risk score improves cardiovascular risk assessment in conjunction with coronary artery calcium scoring
  3. 69223
    “…We investigated whether demographic (age, sex, living arrangement, educational level), lifestyle (history of tobacco smoking, alcohol use), health (asthma, severe heart disease, hypertension, history of stroke, osteoarthritis, rheumatoid arthritis, epilepsy, multiple sclerosis, and migraine), hearing (speech recognition ability in noise, hyperacusis, and occupational noise exposure), and psychological variables (distress, somatization, depression, and anxiety) were potential risk factors for new-onset tinnitus, or associated with annoyance caused by new-onset tinnitus. …”
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    Factors Associated With the Development of Tinnitus and With the Degree of Annoyance Caused by Newly Developed Tinnitus
  4. 69224
    “…CONCLUSIONS: For elderly patients with atrial fibrillation, and without cognitive compromise at baseline that did not have stroke and were adequately treated with warfarin (TTR of 70%) or dabigatran for 2 years, there was no statistical difference at 5% significance level in any of the cognitive outcomes after adjusting for multiple comparisons. …”
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    Effects of dabigatran versus warfarin on 2-year cognitive outcomes in old patients with atrial fibrillation: results from the GIRAF randomized clinical trial
  5. 69225
    “…At eGFR 30 mL/min/1.73m(2), in the chronic pain, heart failure and myocardial infarction cluster in SCREAM, ACM HR is 2.00 (CI 1.62–2.46) and MACE HR is 4.09 (CI 3.39–4.93); in the depression, chronic pain and stroke cluster in SAIL, ACM HR is 1.38 (CI 1.18–1.61) and MACE HR is 1.58 (CI 1.42–1.76). …”
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    The presence and impact of multimorbidity clusters on adverse outcomes across the spectrum of kidney function
  6. 69226
    “…The surgeries were complicated by transient central DI in 21 cases (23.3%), permanent CDI in 6 cases (6.7%), CSF leak in 8 cases (9%), bleeding in 2 (2.2%), stroke in 3 (3.3%) and partial or panhypopituitarism in 58 cases (64.4%). …”
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    LBMON173 Non-functioning Seller Masses: Tumor Types, Surgical Management And Course Over Time
  7. 69227
    “…Studies in adults with Type 2 diabetes (T2D) show blunted reductions in BP and plasma catecholamine levels during sleep that are associated with increased risks for heart failure, stroke, myocardial infarction, and sudden death. In this study, we explored if the circadian rhythm in catecholamines is disrupted in youth-onset T2D. …”
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    OR14-3 Disrupted circadian rhythm in catecholamines in youth-onset Type 2 Diabetes
  8. 69228
    “…The FDA lists cardiovascular risk and stroke as adverse effects of testosterone. Systematic reviews and meta-analyses of published data have limited ability to confirm source data quality and categorisation. …”
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    OR25-5 Adverse Cardiovascular Events and Cause Mortality in Men During Testosterone Treatment: Individual Patient and Aggregate Data Meta-Analyses
  9. 69229
    por LaRovere, Kerri L., Poussaint, Tina Y., Young, Cameron C., Newhams, Margaret M., Kucukak, Suden, Irby, Katherine, Kong, Michele, Schwartz, Stephanie P., Walker, Tracie C., Bembea, Melania M., Wellnitz, Kari, Havlin, Kevin M., Cvijanovich, Natalie Z., Hall, Mark W., Fitzgerald, Julie C., Schuster, Jennifer E., Hobbs, Charlotte V., Halasa, Natasha B., Singh, Aalok R., Mack, Elizabeth H., Bradford, Tamara T., Gertz, Shira J., Schwarz, Adam J., Typpo, Katri V., Loftis, Laura L., Giuliano, John S., Horwitz, Steven M., Biagas, Katherine V., Clouser, Katharine N., Rowan, Courtney M., Maddux, Aline B., Soma, Vijaya L., Babbitt, Christopher J., Aguiar, Cassyanne L., Kolmar, Amanda R., Heidemann, Sabrina M., Harvey, Helen, Zambrano, Laura D., Campbell, Angela P., Randolph, Adrienne G.
    Publicado 2022
    “…Among those with neurologic involvement, 42 (9%) developed acute SARS-CoV-2–related life-threatening conditions, including central nervous system infection/demyelination (n = 23; 15 with possible/confirmed encephalitis, 6 meningitis, 1 transverse myelitis, 1 nonhemorrhagic leukoencephalopathy), stroke (n = 11), severe encephalopathy (n = 5), acute fulminant cerebral edema (n = 2), and Guillain-Barré syndrome (n = 1). …”
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    Changes in Distribution of Severe Neurologic Involvement in US Pediatric Inpatients With COVID-19 or Multisystem Inflammatory Syndrome in Children in 2021 vs 2020
  10. 69230
    “…Other clinical outcomes including stroke, major bleeding, myocardial infarction and permanent pacemaker implantation, were comparable between patients with DM and without DM. …”
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    Diabetes mellitus in transfemoral transcatheter aortic valve implantation: a propensity matched analysis
  11. 69231
    “…Outcomes included death, severe adverse events (death, deep surgical site infection (SSI), myocardial infarction (MI), cardiac arrest, deep vein thrombosis (DVT), pulmonary embolism (PE), sepsis, stroke, compartment syndrome), minor adverse events (acute kidney injury (AKI), pneumonia, superficial SSI, urinary tract infection (UTI)), infectious events (deep SSI, organ/space SSI, superficial SSI, pneumonia, UTI, catheter-related bloodstream infection, osteomyelitis, sepsis), and any adverse event. …”
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    Discriminative Ability for Adverse Outcomes in Traumatic Ankle Fracture: A Comparison of the Modified Charlson Comorbidity Index, Elixhauser Comorbidity Measure, and Modified Frailty Index
  12. 69232
    “…The COVID-19 infection rate was high for patients with pulmonary disease (odds ratio [OR] 1.88; 95% CI 1.70-2.03), dementia (OR 1.75; 95% CI 1.40-2.20), gastrointestinal disease (OR 1.74; 95% CI 1.62-1.88), stroke (OR 1.67; 95% CI 1.23-2.27), hepatobiliary disease (OR 1.31; 95% CI 1.19-1.44), diabetes mellitus (OR 1.28; 95% CI 1.16-1.43), and cardiovascular disease (OR 1.20; 95% CI 1.07-1.35). …”
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    Effect of Comorbidities on the Infection Rate and Severity of COVID-19: Nationwide Cohort Study With Propensity Score Matching
  13. 69233
    “…MAIN OUTCOMES AND MEASURES: The primary efficacy outcome was a composite of cardiovascular (CV) death, stroke, or myocardial infarction (MI). Adjudicated and investigator-reported end points were compared. …”
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    Comparison of Investigator-Reported vs Centrally Adjudicated Major Adverse Cardiac Events: A Secondary Analysis of the COMPASS Trial
  14. 69234
    “…The primary endpoint is a composite of all-cause death, stroke, MI or hospitalization for cardiovascular causes with initial minimum follow-up of 12 months and initial enrolment of 1252 patients with expected recruitment in 24 months. …”
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    Adaptive design with bayesian informed interim decisions: application to a randomized trial of mechanical circulatory support
  15. 69235
    “…Because it is unlikely that ET‐induced improvements in peak V̇O(2) are significantly mediated by an increase in peak heart rate (HR), we aimed to investigate whether baseline peak O(2)‐pulse (V̇O(2) × HR(−1), reflecting the product of stroke volume and arteriovenous oxygen difference), not baseline peak V̇O(2), is inversely associated with the change in peak V̇O(2) (adjusted by body weight) following ET versus guideline control (CON) in patients with HFpEF. …”
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    Peak O(2)‐pulse predicts exercise training‐induced changes in peak V̇O(2) in heart failure with preserved ejection fraction
  16. 69236
    “…Moreover, migraines during pregnancy have been associated with adverse maternal outcomes, including preeclampsia and postpartum stroke. However, due to the lack of a validated instrument for uniform case ascertainment on postpartum migraine headache, there is uncertainty in the reported prevalence in the literature. …”
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    Postpartum Migraine Headache Coding in Electronic Health Records of a Large Integrated Health Care System: Validation Study
  17. 69237
    “…At T0, there were no significant differences in cardiac output, cardiac index (CI), stroke volume index (SVI) or mean arterial pressure between group A and group B (P > 0.05). …”
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    Different positive end expiratory pressure and tidal volume controls on lung protection and inflammatory factors during surgical anesthesia
  18. 69238
    por Lahti, Jari, Tuominen, Samuli, Yang, Qiong, Pergola, Giulio, Ahmad, Shahzad, Amin, Najaf, Armstrong, Nicola J., Beiser, Alexa, Bey, Katharina, Bis, Joshua C., Boerwinkle, Eric, Bressler, Jan, Campbell, Archie, Campbell, Harry, Chen, Qiang, Corley, Janie, Cox, Simon R., Davies, Gail, De Jager, Philip L., Derks, Eske M., Faul, Jessica D., Fitzpatrick, Annette L., Fohner, Alison E., Ford, Ian, Fornage, Myriam, Gerring, Zachary, Grabe, Hans J., Grodstein, Francine, Gudnason, Vilmundur, Simonsick, Eleanor, Holliday, Elizabeth G., Joshi, Peter K., Kajantie, Eero, Kaprio, Jaakko, Karell, Pauliina, Kleineidam, Luca, Knol, Maria J., Kochan, Nicole A., Kwok, John B., Leber, Markus, Lam, Max, Lee, Teresa, Li, Shuo, Loukola, Anu, Luck, Tobias, Marioni, Riccardo E., Mather, Karen A., Medland, Sarah, Mirza, Saira S., Nalls, Mike A., Nho, Kwangsik, O’Donnell, Adrienne, Oldmeadow, Christopher, Painter, Jodie, Pattie, Alison, Reppermund, Simone, Risacher, Shannon L., Rose, Richard J., Sadashivaiah, Vijay, Scholz, Markus, Satizabal, Claudia L., Schofield, Peter W., Schraut, Katharina E., Scott, Rodney J., Simino, Jeannette, Smith, Albert V., Smith, Jennifer A., Stott, David J., Surakka, Ida, Teumer, Alexander, Thalamuthu, Anbupalam, Trompet, Stella, Turner, Stephen T., van der Lee, Sven J., Villringer, Arno, Völker, Uwe, Wilson, Robert S., Wittfeld, Katharina, Vuoksimaa, Eero, Xia, Rui, Yaffe, Kristine, Yu, Lei, Zare, Habil, Zhao, Wei, Ames, David, Attia, John, Bennett, David A., Brodaty, Henry, Chasman, Daniel I., Goldman, Aaron L., Hayward, Caroline, Ikram, M. Arfan, Jukema, J. Wouter, Kardia, Sharon L. R., Lencz, Todd, Loeffler, Markus, Mattay, Venkata S., Palotie, Aarno, Psaty, Bruce M., Ramirez, Alfredo, Ridker, Paul M., Riedel-Heller, Steffi G., Sachdev, Perminder S., Saykin, Andrew J., Scherer, Martin, Schofield, Peter R., Sidney, Stephen, Starr, John M., Trollor, Julian, Ulrich, William, Wagner, Michael, Weir, David R., Wilson, James F., Wright, Margaret J., Weinberger, Daniel R., Debette, Stephanie, Eriksson, Johan G., Mosley, Thomas H., Launer, Lenore J., van Duijn, Cornelia M., Deary, Ian J., Seshadri, Sudha, Räikkönen, Katri
    Publicado 2022
    “…Hence, we examined the associations of common genetic variants with verbal short-term memory and verbal learning in adults without dementia or stroke (N = 53,637). We identified novel loci in the intronic region of CDH18, and at 13q21 and 3p21.1, as well as an expected signal in the APOE/APOC1/TOMM40 region. …”
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    Genome-wide meta-analyses reveal novel loci for verbal short-term memory and learning
  19. 69239
    “…Main outcomes were death within 28 days after admission and new hospitalizations for heart failure (HF), chronic kidney disease (CKD), cardiorenal disease (CRD; composite of HF and CKD), myocardial infarction (MI) and stroke during 1 year of follow-up. RESULTS: Number of deaths and CRD events were 2025 and 442 with COVID-19 and 259 and 525 with influenza, respectively. …”
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    Patients with type 1 and type 2 diabetes hospitalized with COVID-19 in comparison with influenza: mortality and cardiorenal complications assessed by nationwide Swedish registry data
  20. 69240
    “…We extracted personalised treatment effect estimates for the primary outcome, time-to-first major adverse cardiovascular event (MACE; cardiovascular death, myocardial infarction or acute coronary syndrome, stroke, and acute decompensated heart failure), through iterative Cox regression analyses providing average hazard ratio (HR) estimates weighted for the phenotypic distance of each participant from the index patient of each iteration. …”
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    Individualising intensive systolic blood pressure reduction in hypertension using computational trial phenomaps and machine learning: a post-hoc analysis of randomised clinical trials
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