“…Protein folding research stalled for decades because conventional experiments indicated that proteins fold slowly and in single strokes, whereas theory predicted a complex interplay between dynamics and energetics resulting in myriad microscopic pathways. …”
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“…A model of muscle contraction is proposed, assuming loose coupling between power strokes and ATP hydrolysis of a myosin head. The energy borrowing mechanism is introduced in a cross-bridge cycle that borrows energy from the environment to cover the necessary energy for enthalpy production during sliding movement. …”
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“…(1) Background: We investigated the age of swimming champions in all strokes and race distances in World Championships (1994–2013) and Olympic Games (1992–2012); (2) Methods: Changes in age and swimming performance across calendar years for 412 Olympic and world champions were analysed using linear, non-linear, multi-level regression analyses and MultiLayer Perceptron (MLP); (3) Results: The age of peak swimming performance remained stable in most of all race distances for world champions and in all race distances for Olympic champions. …”
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“…Each of the three medicines under consideration is associated with a similar overall risk of CV events (fatal and nonfatal heart attacks and strokes). However, there are consistent differences in effects on blood pressure (BP), reported both from trials using ambulatory techniques and from meta-analyses of randomized trials, reporting investigator determined effects, with etoricoxib being associated with a greater propensity to destabilize BP control than either diclofenac or celecoxib.…”
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“…Materials and Methods: Twelve male elite athletes performed forehand topspin strokes with long and short chasse steps in this study, respectively. …”
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“…Background and Objectives: Metabolic syndrome (MetS) is a multiple risk factor for atherosclerosis, cardiovascular disease, type 2 diabetes and strokes. One-third of middle-age women are at risk of MetS, which predisposes them to type 2 diabetes and cardiovascular disease. …”
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“…CVD was defined as coronary artery diseases, strokes, and peripheral artery diseases. Median serum calprotectin levels were 1.04 mg/L [IQR: 0.73–1.46 mg/L] and were higher in women (1.11 mg/L) than men (0.96 mg/L, p = 0.007). …”
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“…The main symptoms are migraines, psychiatric disorders, recurrent strokes, and dementia. Omic technologies allow the massive study of different molecules for understanding diseases in a non-biased manner or even for discovering targets and their possible treatments. …”
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“…Once such tools are developed, it will be possible to improve FDR methods and quantify complex glycoproteomes with acceptable confidence, rather than potentially misleading broad strokes.…”
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“…The aim of the study was to investigate the effect of start and turn performances on race times in top-elite female swimmers and provide benchmarks for all performance levels, all swimming strokes, and all race distances of the European Short-Course Championships (EC). …”
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“…For the first, wear studies were performed in a controlled pilot plant environment after 800 hot stamping strokes in an omega tool configuration. On the second, a demonstrator tool based on a commercial tool with hot spot issues, was produced by 3D printing including surface-conformal cooling channels. …”
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“…Line drawings convey meaning with just a few strokes. Despite strong simplifications, humans can recognize objects depicted in such abstracted images without effort. …”
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“…The variables affecting the synthesis (number of coating cycles, the concentration of dopamine, and needle surface pre-treatment) and the extraction (sample salinity, sample loading cycles, and the number of elution strokes) were studied in depth. Under the optimum conditions, a matrix-matched calibration model was built. …”
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“…On follow-up, he developed profound vision impairment, intractable seizures, and metabolic strokes. A literature review of reported biallelic OPA1-related Behr syndrome was performed. …”
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“…BACKGROUND: Many diabetic patients take a daily low-dose of aspirin because they are two to three times more likely to suffer from heart attacks and strokes, but its role in obstructive lung diseases is less clear. …”
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“…Thirty-four participants performed contractile property measurements (stiffness, tone, elasticity and time to relaxation) on the dominant and non-dominant extremities including nine muscle groups involved in the kinetic chain of main tennis strokes. Significant differences (p≤0.05) and small-to-moderate effect sizes for greater stiffness and tone were found for the dominant biceps femoris (-11.1% and -5.6%; ES=0.53 and 0.54) and the non-dominant vastus medialis (5.4% and 3.2%; ES=-0.33 and -0.41), while greater tone was present in the non-dominant pectoralis major (4.0%; ES=-0.56). …”
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“…OBJECTIVES: A case report is presented alongside a review of the relevant literature regarding the relationship between Bipolar disorder and strokes. METHODS: We present the case of a 54-year-old man who, after suffering a pontine hemorrhage, developed a depressive mood for which he was treated with Sertraline 50 mg. …”
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“…Regardless, AF has been implicated in 25% to 30% of cryptogenic strokes. Natriuretic peptide(NP)s have been shown to be elevated in AF, with higher levels of both NT-proBNP and BNP being predictive of incidental AF. …”
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“…The present review draws attention to the role of vasopressin (AVP) and some other cardiovascular peptides (angiotensins, oxytocin, cytokines) in the regulation of the cardiovascular system in health and cardiovascular diseases, especially in post-infarct heart failure, hypertension and cerebrovascular strokes. Vasopressin is synthesized mostly by the neuroendocrine cells of the hypothalamus. …”
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“…She had a background of SLE, triple antibody-positive APS (previous DVT, pregnancy loss and strokes), hypertension, a metallic mitral valve, a previous myocardial infarction and pre-existing visual impairment due to a prior intra-cerebral bleed related to anticoagulation. …”
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