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Historia
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Teoría de las estructuras
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31
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29
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1981“…The outer layers of a range of plant tissues, including flower petals, leaves and fruits, exhibit an intriguing variation of microscopic structures. Some of these structures include ordered periodic multilayers and diffraction gratings that give rise to interesting optical appearances. …”
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1982“…Questions such as what principles govern their structural organization, what factors guide their assembly, how these viruses integrate multifarious functions into one unique structure have enamored researchers for years. …”
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1983“…Nevertheless, the dynamics of co-adaptation generates a structured environment in which only a subset of environmental states appear with high probability (niches) and in which agents accrue positive wealth. …”
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1984“…Many complex networks show signs of modular structure, uncovered by community detection. Although many methods succeed in revealing various partitions, it remains difficult to detect at what scale some partition is significant. …”
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1985por Butenas, Saulius“…However there is a lack of agreement related to the mechanism and processes leading to alterations in TF function. In this paper TF structure, presentation, and function, and controversies concerning these features are discussed.…”
Publicado 2012
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1986por Lundstrom, K“…Structure determination has already proven useful for lead optimization and direct drug design. …”
Publicado 2007
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1987“…Recent high and low resolution structural and dynamic studies now suggest more nuanced overall protein structures than previously realized. …”
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1988por Delporte, ChristineEnlace del recurso
Publicado 2013
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1989“…The enzymes that catalyse these reactions must all recognise and bind oestrogen but, despite this, they have diverse structures. This review looks at each of these enzymes in turn, describing the structure and discussing the mechanism of the catalysed reaction. …”
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1990“…Here, we introduce structural metabolic control as a framework to examine individual reactions' potential to control metabolic functions, such as biomass production, based on structural modeling. …”
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1991“…The present review summarizes some of these findings with a particular focus on the mechanisms driving this form of structural plasticity and its possible impact on synaptic structure and function.…”
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1992“…Significant evidence of episodic positive selection was obtained for several sites within coding sequences of structural and non-structural proteins. This corroborates well with known phenotypic properties such as antigenicity of structural proteins. …”
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1993“…Improvements in the fields of membrane-protein molecular biology and biochemistry, technical advances in structural data collection and processing, and the availability of numerous sequenced genomes have paved the way for membrane-protein structural genomics efforts. …”
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1994por Akiva, Eyal, Brown, Shoshana, Almonacid, Daniel E., Barber, Alan E., Custer, Ashley F., Hicks, Michael A., Huang, Conrad C., Lauck, Florian, Mashiyama, Susan T., Meng, Elaine C., Mischel, David, Morris, John H., Ojha, Sunil, Schnoes, Alexandra M., Stryke, Doug, Yunes, Jeffrey M., Ferrin, Thomas E., Holliday, Gemma L., Babbitt, Patricia C.“…The Structure–Function Linkage Database (SFLD, http://sfld.rbvi.ucsf.edu/) is a manually curated classification resource describing structure–function relationships for functionally diverse enzyme superfamilies. …”
Publicado 2014
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1995“…The 14 currently available structures of ABC transporters have greatly advanced insight into the transport mechanism and revealed a tremendous structural diversity. …”
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1996“…Our analysis also reveals that this general motif is associated with the formation of tertiary structure interactions. Greater knowledge about the dynamics at the helix-junctions in the secondary structure should enhance the prediction of RNA secondary structure with a richer set of energetic rules and help better understand the folding of a secondary structure into its three-dimensional structure. …”
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1997“…[Image: see text] Simple halogen substituents frequently afford key structural features that account for the potency and selectivity of natural products, including antibiotics and hormones. …”
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1998“…The controversy surrounding the three-dimensional structure of grana, its recent resolution by tomographic analyses, and the role of the CURVATURE THYLAKOID1 (CURT1) proteins in supporting grana formation are also discussed. …”
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1999
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2000“…We provide 3D-reconstructions of native dyneins in three conformational states, in situ, allowing us to propose a molecular model of the structural cycle underlying dynein movement.…”
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