“…RNA secondary structures with pseudoknots are often predicted by minimizing free energy, which is NP-hard. …”
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“…The large polymorphisms are termed structural variants (SVs). SVs have received significant attention in human genetics and were found to be responsible for various chronic diseases. …”
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Materias: “…Part II: Centrosome assembly and structure…”
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“…In the present study bioinformatic analysis showed the presence of one or more TCTP genes per genome in plants with highly conserved signatures and subtle variations at the level of primary structure but with more noticeable differences at the level of predicted three-dimensional structures. …”
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“…The detailed three-dimensional profiles of RNA CNG repeats can be used in screening of compound libraries for potential therapeutics and in structure-based drug design. Here is a brief survey of the CNG structures published to date.…”
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“…BACKGROUND: Analysis of data from multiple sources has the potential to enhance knowledge discovery by capturing underlying structures, which are, otherwise, difficult to extract. …”
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“…Functions in supercoiling-dependent RNA transcription or as a ‘structural code’ for DNA packaging have been suggested. …”
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“…In the present review we summarize the structural insights and biochemistry of various phosphatases in regulating phosphoinositide metabolism. …”
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“…BACKGROUND: With the continuous discovery of novel RNA molecules with key cellular functions and of novel pathways and interaction networks, the need for structural information of RNA is still increasing. In order to predict structure of long RNA and understand its natural folding mechanism, exploring the characteristic of RNA structure is an important issue. …”
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“…Although we have made remarkable progress unraveling the mechanics of life's individual building blocks, our understanding of how they give rise to the mechanics of larger-scale biological structures is still poor. Unlike the engineered macroscopic structures that we commonly build, biological structures are dynamic and self-organize: they sculpt themselves and change their own architecture, and they have structural building blocks that generate force and constantly come on and off. …”
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“…One Cl atom and one F atom of the di­chloro­fluoro­methyl­thio group are disordered over two sets of sites with an occupancy ratio of 0.605 (9):0.395 (9). In the crystal structure, two C—H⋯Cl hydrogen bonds link adjacent mol­ecules, forming dimers with R (2) (2)(14) loops. …”
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“…The improvements in the crystal structure refinement program SHELXL have been closely coupled with the development and increasing importance of the CIF (Crystallographic Information Framework) format for validating and archiving crystal structures. …”
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“…We suggest the temporal structure within retrieved neural representations may be key to their function. …”
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“…Recent progress with the X-ray crystal structure determination of a variety of bacterial and eukaryotic ABC transporters has helped to advance our understanding of the ATP hydrolysis-driven transport mechanism but has also illustrated the large structural and functional diversity within the family.…”
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Materias: “…Structural Biology…”
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“…A large number of studies have demonstrated the existence of metabolic covalent modifications in different molecular structures, which are able to store biochemical information that is not encoded by DNA. …”
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“…The mol­ecular structure of ruthenocenecarbo­nitrile, [Ru(η(5)-C(5)H(4)C N)(η(5)-C(5)H(5))], exhibits point group symmetry m, with the mirror plane bis­ecting the mol­ecule through the C N substituent. …”
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