“…The first total synthesis of the proposed structure of astakolactin, a sesterterpene metabolite isolated from the marine sponge Cacospongia scalaris, has been achieved, mainly featuring Johnson–Claisen rearrangement, asymmetric Mukaiyama aldol reaction and MNBA-mediated lactonization.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…It is suggested that a generalized model of a structural/basic unit (crystalline, non-crystalline or of any scale), which depends on the interatomic (including electronic) interactions, the spatial distribution of the atoms and electrons, the number of atoms and free volume fraction present in the structural/basic unit and the experimental conditions should serve the purpose. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso

Materias: “…Structural Biology…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The two planes form a dihedral angle of 85.31 (2)°, and are linked via C—H⋯O hydrogen bonds and C—H⋯π inter­actions, forming a three-dimensional framework structure.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This study reveals for the first time the structural basis for both intra-module and inter-module substrate transfer in polyketide synthases, and establishes a new model for molecular dissection of these multifunctional enzyme systems.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Further progress promises a general technique for structure determination of difficult crystals.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…However, for kafirin, the prolamin from sorghum, its composition, structure, morphology, and self-assembly behaviors have not been fully characterized. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Lack of sufficient structural detail has impeded understanding of RyR gating and regulation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

Enlace del recurso
Enlace del recurso
Enlace del recurso

“…OBJECTIVE: Structural changes of osteoarthritis (OA) may occur in the absence of pain. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The amorphous-to-crystalline transition and the structure of amorphous In(2)O(3) were investigated by grazing angle X-ray diffraction (GIXRD), Hall transport measurement, high resolution transmission electron microscopy (HRTEM), electron diffraction, extended X-ray absorption fine structure (EXAFS), and ab initio molecular dynamics (MD) liquid-quench simulation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This review describes some of the molecular and structural biology of this unusual enzyme complex. The presenilin complex is a bilobed structure. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The algorithms are compared with a classification based on observed flow directions (considered the gold standard), and with an existing resistance‐based method that relies only on structural data. RESULTS: The first algorithm, developed for networks with one arteriolar and one venular tree, performs well in identifying arterioles and venules and is robust to parameter changes, but incorrectly labels a significant number of capillaries as arterioles or venules. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Our results point to the possibility of selectively controlling the wetting behavior by engineering the surface structure.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This study suggests that migraine leads to a reduction in the peripapillary RNFL thickness and to thinning in choroidal structures. These findings can be explained by a chronic ischemic insult related to migraine pathogenic mechanisms and these findings are considered supportive of the relationship between glaucoma and migraine.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…p73 is a structural and functional homologue of the p53 tumor suppressor protein. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…MicroED is a recently developed method that uses electron diffraction for structure determination from very small three-dimensional crystals of biological material. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso