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  1. 383501
    “…The patients were divided into four groups according to their treatment regimens as follows: group A: 25 patients who received sofosbuvir (400 mg) and daclatasvir (60 mg) daily for 12 weeks; group B: 25 patients who received sofosbuvir (400 mg) and ledipasvir (90 mg) daily for 12 weeks; group C: 25 patients who received ombitasvir (12.5 mg), paritaprevir (75 mg), and ritonavir (50 mg) daily for 12 weeks; and group D: 25 patients who received sofosbuvir (400 mg) and simeprevir (150 mg) daily for 12 weeks. All patients were subjected to the following investigations: HCV quantitative PCR before and after 12 weeks of treatment, clinical and laboratory metabolic evaluation including alfa-fetoprotein level, thyroid profile assessment, ferritin level, pelvi-abdominal ultrasound, and FibroScan examination. …”
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    The effect of different direct antivirals on hepatic steatosis in nondiabetic and naïve hepatitis C-infected Egyptian patients
  2. 383502
    “…Sensitivity analyses did not alter our primary results. These results are subject to the limitations and assumptions of MR, which in this case reflects interpretation of these SNP effects as causally acting through blockade of IL6R, and reflect lifetime exposure to IL6R blockade, rather than the effect of therapeutic IL6R blockade. …”
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    Therapeutic potential of IL6R blockade for the treatment of sepsis and sepsis-related death: A Mendelian randomisation study
  3. 383503
    “…MAIN OUTCOMES AND MEASURES: Change-from-baseline plasma concentrations for Δ9-THC or Δ9-THC metabolites and scores for subjective drug effects, cognitive and psychomotor performance, and vital signs. …”
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    Assessment of Orally Administered Δ9-Tetrahydrocannabinol When Coadministered With Cannabidiol on Δ9-Tetrahydrocannabinol Pharmacokinetics and Pharmacodynamics in Healthy Adults: A Randomized Clinical Trial
  4. 383504
    por Reis, Gilmar, Moreira Silva, Eduardo A.S., Medeiros Silva, Daniela C., Thabane, Lehana, Campos, Vitoria H.S., Ferreira, Thiago S., Santos, Castilho V.Q., Nogueira, Ana M.R., Almeida, Ana P.F.G., Savassi, Leonardo C.M., Figueiredo-Neto, Adhemar D., Dias, Ana C.F., Freire Júnior, Adelino M., Bitarães, Carina, Milagres, Aline C., Callegari, Eduardo D., Simplicio, Maria I.C., Ribeiro, Luciene B., Oliveira, Rosemary, Harari, Ofir, Wilson, Lindsay A., Forrest, Jamie I., Ruton, Hinda, Sprague, Sheila, McKay, Paula, Guo, Christina M., Limbrick-Oldfield, Eve H., Kanters, Steve, Guyatt, Gordon H., Rayner, Craig R., Kandel, Christopher, Biondi, Mia J., Kozak, Robert, Hansen, Bettina, Zahoor, M. Atif, Arora, Paul, Hislop, Colin, Choong, Ingrid, Feld, Jordan J., Mills, Edward J., Glenn, Jeffrey S.
    Publicado 2023
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    Early Treatment with Pegylated Interferon Lambda for Covid-19
  5. 383505
    “…All participants who were diagnosed with COVID-19 and achieved remission were approached in an outpatient department (OPD) setting and signed an informed consent form and were evaluated by standard questionnaires at clinics after remission from COVID-19 at King Abdulaziz Medical City in Riyadh, Saudi Arabia. A total of 343 subjects who fit the inclusion criteria of any patients who have been diagnosed with COVID-19 and achieved remission were included in the study. …”
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    The Incidence of Long-Term Fatigue in Patients Who Achieved Remission From COVID-19 at King Abdulaziz Medical City
  6. 383506
    “…Outcome measures, including community participation, quality of life, and the occurrence and subjective impact of medically serious secondary conditions and rehospitalizations, were assessed at baseline after randomization and at subsequent time points to allow between-group comparisons. …”
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    Feasibility of a Community-Based, Online, Peer-Supported Spinal Cord Injury Self-management Intervention: Protocol for a Pilot Wait-Listed Randomized Trial
  7. 383507
    “…BACKGROUND: Since the advent of the COVID-19 pandemic, individuals of Asian descent (colloquial usage prevalent in North America, where “Asian” is used to refer to people from East Asia, particularly China) have been the subject of stigma and hate speech in both offline and online communities. …”
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    Development of a COVID-19–Related Anti-Asian Tweet Data Set: Quantitative Study
  8. 383508
    “…Main outcome measures VA, CST, EZ, and DRIL at diagnosis and 6 months. Results Sixty subjects (30 interventional and 30 observational arms) were recruited for this study. …”
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    Evaluation of Anatomical and Functional Outcome of Epiretinal Membrane Surgery in Idiopathic Epiretinal Membrane Patients
  9. 383509
    “…METHOD: We used food frequency questionnaire (FFQ) data from 2,696 healthy FDR subjects of the Crohn’s Colitis Canada- Genes, Environment, Microbial (CCC-GEM) project. …”
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    A218 ASSOCIATIONS BETWEEN ADHERENCE TO LITERATURE-DERIVED DIETARY INDICES AND PRE-DISEASE BIOMARKERS: IMPLICATIONS FOR CROHN’S DISEASE PREVENTION
  10. 383510
    “…METHODS: We used baseline data of the DELCODE cohort of 437 subjects (127 controls, 168 SCD, 87 MCI, 55 AD patients) which underwent lumbar puncture, MRI scanning, and neuropsychological assessment. …”
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    Exploring the ATN classification system using brain morphology
  11. 383511
    “…The study started after a 14-weeks post-surgery rehabilitation program, which was identical for all subjects. After this initial rehabilitation period, athletes were randomly assigned to three experimental groups, ECC (n = 10), PLYO (n = 10), and COMB (n = 10), and a control group (CON: n = 10). …”
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    The effects of different rehabilitation training modalities on isokinetic muscle function and male athletes’ psychological status after anterior cruciate ligament reconstructions
  12. 383512
    “…The percentages of students with highly functional, moderately dysfunctional and severely dysfunctional family functioning were 48.23%, 43.91 and 7.86% at T1 and 46.20%, 45.28%, and 8.52 at T4, respectively. The percentage of subjects with active coping style was 23.9%, negative coping style was 17.4%, strong response coping was 26.9%, and weak response coping was 31.7%. …”
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    Impact of family functioning on mental health problems of college students in China during COVID-19 pandemic and moderating role of coping style: a longitudinal study
  13. 383513
    “…METHODS: We included patients who visited Alzheimer Center Amsterdam 6 months to 1 week before the first Dutch COVID-19 lockdown, and had a second visit 1 year later, after this lockdown period (n = 113; 66 ± 7 years old; 30% female; n = 55 dementia, n = 31 mild cognitive impairment (MCI), n = 18 subjective cognitive decline (SCD), n = 9 postponed diagnosis). …”
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    Steeper memory decline after COVID-19 lockdown measures
  14. 383514
    “…Verbatim interview transcripts were subject to thematic and content analysis. RESULTS: In total, there were 28 participants (non-radiographic axSpA, n = 12; ankylosing spondylitis, n = 16), from the US (n = 20) and Germany (n = 8). …”
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    Qualitative concept elicitation and cognitive debriefing interviews of symptoms, impacts and selected customized PROMIS(®) Short Forms: a study in patients with axial spondyloarthritis
  15. 383515
    “…Tissue and plasma samples were subjected to targeted bisulfite sequencing with a lung cancer specific panel targeting 9,307 differential methylation regions (DMRs). …”
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    Accurate detection of early-stage lung cancer using a panel of circulating cell-free DNA methylation biomarkers
  16. 383516
    “…BACKGROUND: Forensic biology is a subject in the field of forensic science that stresses practical teaching and training in laboratory skills. …”
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    QR code technology in individual identification training provides an introduction in hands-on forensic DNA genotyping to medical students
  17. 383517
    “…Psychosocial data (eg, emotional distress, fatigue, quality of life, subjective well-being, sleep problems, and appetite loss) will be collected by questionnaires via a smartphone app, and physiological data (eg, heart rate, skin temperature, and movement through step count) will be collected by a customizable smart wrist-worn sensor device. …”
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    Digital Guardian Angel Supported by an Artificial Intelligence System to Improve Quality of Life, Well-being, and Health Outcomes of Patients With Cancer (ONCORELIEF): Protocol for a Single Arm Prospective Multicenter Pilot Study
  18. 383518
    “…Using the Topocon swept source optical coherence tomograph (SS-OCT) and fundus camera to detect the parameters, we have assessed the relative position and size of ONH, tilt and rotation of ONH, angle α (Defined as between retinal temporal arterial vascular arcades was measured from the centre of ONH with 250 pixels’ radius), size and type of peripapillary atrophy (PPA), the thickness of peripapillary retinal nerve fiber layer (PRNFL), peripapillary choriodal thickness (PCT) and peripapillary scleral thickness (PST), and peripapillary vessel density (PVD). In addition, subjects were grouped as SHM and PM according to retinopathy, and the above parameters were compared between the two groups. …”
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    Morphology and microcirculation changes of the optic nerve head between simple high myopia and pathologic myopia
  19. 383519
    “…METHODS: A case–control study of 1171 subjects was included to determine the association of miR-146a rs2910164 and miR-34b rs4938723 polymorphisms with ACS risk. …”
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    MiR-146a rs2910164 (G/C) polymorphism is associated with the development and prognosis of acute coronary syndromes: an observational study including case control and validation cohort
  20. 383520
    “…RESULTS: Overall, 18 RCTs involving 1063 subjects were evaluated. Compared with placebo or other hypoglycemic drugs, SGLT-2 inhibitors significantly reduced visceral adipose tissue (standard mean deviation [SMD] = − 1.42, 95% confidence interval [CI] [− 2.02, − 0.82], I(2) = 94%, p < 0.0001), subcutaneous adipose tissue (SMD = − 1.21, 95% CI [− 1.99, − 0.42], I(2) = 93%, p = 0.003), ectopic liver adipose tissue (SMD = − 0.70, 95% CI [− 1.20, − 0.20], I(2) = 73%, p = 0.006). …”
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    Effects of SGLT-2 inhibitors on adipose tissue distribution in patients with type 2 diabetes mellitus: a systematic review and meta-analysis of randomized controlled trials
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