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  1. 4421
    “…However, to secrete antibodies, a complex cellular response is set up, including not only the activation and differentiation of B cells into antibody-secreting cells, but also the participation of other cell subsets in the germinal center reactions. Therefore, a better understanding of how B cell subsets are stimulated during malaria infection will provide essential insights toward the design of potent interventions.…”
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    To B or Not to B: Understanding B Cell Responses in the Development of Malaria Infection
  2. 4422
    “…Naïve CD4(+) T cell differentiate into effector and regulatory subsets of helper T (Th) cells in various pathophysiological conditions and modulate tissue inflammation in autoimmune diseases. …”
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    Metabolic Checkpoints in Differentiation of Helper T Cells in Tissue Inflammation
  3. 4423
    “…We summarize the Th2 immune-inducing DC subsets, the genetic and environmental factors involved in DC-mediated Th2 immunity, and current therapeutic approaches for Th2-mediated immune disorders. …”
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    Dendritic Cell-Mediated Th2 Immunity and Immune Disorders
  4. 4424
    “…PD1 and CTLA4 are dynamically expressed on different T cell subsets that can either disrupt or sustain tumor growth. …”
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    Prognostic Factors and Biomarkers of Responses to Immune Checkpoint Inhibitors in Lung Cancer
  5. 4425
    “…The cytokine signatures of ILC subsets mirror those of corresponding helper T-cell subsets. …”
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    Helper Innate Lymphoid Cells in Human Tumors: A Double-Edged Sword?
  6. 4426
    “…Mating-defective variants led to decreased expression of distinct subsets of genes necessary for mating. Hyper-invasive variants also decreased expression of subsets of genes involved in mating, but increased the expression of other subsets of genes associated with the cellular response to osmotic stress. …”
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    Binding and Regulation of Transcription by Yeast Ste12 Variants To Drive Mating and Invasion Phenotypes
  7. 4427
    por Wheaton, Joshua D., Ciofani, Maria
    Publicado 2020
    “…This defect is compounded by loss of a separate effector program found in both major colonic Treg subsets that includes the cytolytic effector molecule granzyme B. …”
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    JunB Controls Intestinal Effector Programs in Regulatory T Cells
  8. 4428
    “…Our study provides the unbiased and more comprehensive molecular identities of human NKT subsets, which will eventually lead the way to tailored therapies targeting selected NKT subsets.…”
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    Single-Cell RNA-Seq Analysis Uncovers Distinct Functional Human NKT Cell Sub-Populations in Peripheral Blood
  9. 4429
    por Johnson, Louise A.
    Publicado 2021
    “…This review details the immune cell subsets in afferent and efferent lymph, and explores the mechanisms by which endothelial cells of the lymphatic system regulate such trafficking, for immune surveillance and tolerance during steady-state conditions, and in response to infection, acute and chronic inflammation, and subsequent resolution.…”
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    In Sickness and in Health: The Immunological Roles of the Lymphatic System
  10. 4430
    “…Since unconventional T cell lineages comprise discrete functional subsets, they can mediate both anti- and protumoral activities. …”
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    Regulation and Functions of Protumoral Unconventional T Cells in Solid Tumors
  11. 4431
    “…The analysis included flow cytometry evaluation of blood MDSCs subsets, correlation their level with the tumor stage and T cell subsets. …”
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    Mo-MDSCs are pivotal players in colorectal cancer and may be associated with tumor recurrence after surgery
  12. 4432
    por Blakeman, Sam, Mareschal, Denis
    Publicado 2022
    “…We take inspiration from selective attention in biological agents and propose a novel algorithm called Selective Particle Attention (SPA), which selects subsets of existing representations for Deep RL. Crucially, these subsets are not learned through backpropagation, which is slow and prone to overfitting, but instead via a particle filter that rapidly and flexibly identifies key subsets of features using only reward feedback. …”
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    Selective particle attention: Rapidly and flexibly selecting features for deep reinforcement learning
  13. 4433
    “…Within NOD mice deficient in particular γδ T cell subsets, we noted that changes in the abundance of non-targeted T cell types also occurred, which varied depending upon the γδ T cells that were missing. …”
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    A Distinctive γδ T Cell Repertoire in NOD Mice Weakens Immune Regulation and Favors Diabetic Disease
  14. 4434
    “…The database contains about 1913 HNH domain containing proteins, and is classified into 10 subsets based on the sequence pattern. Each of these subsets has unique signature sequences. …”
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    HNHDb: A database on pattern based classification of HNH domains reveals functional relevance of sequence patterns and domain associations.
  15. 4435
    “…Pancreatic tumors are rich in immune cell infiltrates that include CD4(+) T-cell subsets encompassing both regulatory T cells and T(H)17 cells. …”
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    Immune cells in pancreatic cancer: Joining the dark side
  16. 4436
    “…Recent studies have revealed a complex and diverse composition of group 1 ILC subsets infiltrating different tumors. In this review, we will outline the commonalities and differences between group 1 ILC subsets in both mice and humans, discuss how the tissue and tumor microenvironment shapes their phenotype and functions, as well as describe their contrasting roles in the response to different cancers.…”
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    To kill or not to kill – The role of the tumor microenvironment in shaping group 1 ILC functions
  17. 4437
    “…Here, we provide a detailed protocol for the analysis of liver macrophage subsets in mice with non-alcoholic fatty liver disease (NAFLD) and early NASH using flow cytometry and immunofluorescence (IF). …”
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    Comprehensive analysis of liver macrophage composition by flow cytometry and immunofluorescence in murine NASH
  18. 4438
    “…Moreover, CD28- subsets rather than CD28+ subsets predominantly contributed to the significant accumulation of PD-1(+)TIGIT(+) T cells in AML patients. …”
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    Loss of CD28 expression associates with severe T-cell exhaustion in acute myeloid leukemia
  19. 4439
    “…To dissect the contribution of lung myeloid subsets to airway inflammation, we generate a longitudinal scRNA-Seq dataset of airway cells, and map these subsets to corresponding populations in the human lung. …”
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    TREM2(+) and interstitial-like macrophages orchestrate airway inflammation in SARS-CoV-2 infection in rhesus macaques
  20. 4440
    “…Circulating monocytes and three subsets were significantly higher in PG and RG compared to NG. …”
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    Elevated circulating monocytes and monocyte activation in COVID-19 convalescent individuals
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