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4501“…Recent studies suggest that miRNAs play an important role in the development and function of all subsets of CD4 T cells. In current review, we focused on how various miRNAs are regulated by cell's extrinsic and intrinsic signaling, and how miRNAs affect the transdifferentiation of subsets of CD4 T cell and controls their plasticity during inflammation and tolerance.…”
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4502Intestinal lamina propria dendritic cells maintain T cell homeostasis but do not affect commensalismpor Welty, Nathan E., Staley, Christopher, Ghilardi, Nico, Sadowsky, Michael J., Igyártó, Botond Z., Kaplan, Daniel H.“…This subset was ablated in huLangerin-DTA mice, resulting in reduced LP Th17 cells without affecting Th1 or T reg cells. …”
Publicado 2013
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4503por Tan, Jonathan K H, Quah, Ben J C, Griffiths, Kristin L, Periasamy, Pravin, Hey, Ying-Ying, O’Neill, Helen C“…Antigen-presenting cells (APC), like dendritic cells (DC), are essential for T-cell activation, leading to immunity or tolerance. Multiple DC subsets each play a unique role in the immune response. …”
Publicado 2011
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4504por Su, Xiaoping, Qian, Cheng, Zhang, Qian, Hou, Jin, Gu, Yan, Han, Yanmei, Chen, Yongjian, Jiang, Minghong, Cao, Xuetao“…Dendritic cells (DCs) are critical to initiate the immune response and maintain tolerance, depending on different status and subsets. The expression profiles of microRNAs (miRNAs) in various DC subsets and haematopoietic stem cells (HSCs), which generate DCs, remain to be fully identified. …”
Publicado 2013
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4505“…There are two major MΦ subsets (M1 and M2 MΦs) that are phenotypically and functionally different. …”
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4506por Myśliwska, Jolanta, Ryba-Stanisławowska, Monika, Smardzewski, Marcin, Słomiński, Bartosz, Myśliwiec, Małgorzata, Siebert, Janusz“…Our results indicate that three monocyte subsets are distinguishable in the groups of young diabetic patients and the healthy, similarly to in the blood of adults. …”
Publicado 2014
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4507por Kumar, Nathella Pavan, Sridhar, Rathinam, Hanna, Luke E., Banurekha, Vaithilingam V., Nutman, Thomas B., Babu, Subash“…BACKGROUND: Circulating T follicular helper (Tfh) cells represent a distinct subset of CD4(+) T cells and are important in immunity to infections. …”
Publicado 2014
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4508por Hodge, G., Upham, J. W., Chang, A. B., Baines, K. J., Yerkovich, S. T., Pizzutto, S. J., Hodge, S.“…Relatively little is known about the nature of systemic inflammation in these children, especially the contribution of specific pro-inflammatory and cytotoxic lymphocyte subsets: T-cells, natural killer (NK) cells and NKT-like cells. …”
Publicado 2015
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4509“…Here, we perform bioinformatical parsing of human ‘folding-on-binding’ (FB) proteins, into four subsets: Ordered regions, FB regions, Disordered regions that surround FB regions (‘Disordered-around-FB’), and Other-Disordered regions. …”
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4510“…This asymmetry is actively maintained by membrane-embedded lipid transporters, but there is only limited data available about the molecular identity of the predominantly active transporters and their substrate specificity in different leukocyte subsets. We demonstrate here that the P4-type ATPase ATP11C mediates significant flippase activity in all murine leukocyte subsets. …”
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4511“…The study was aimed at assessing T cell subsets of peripheral blood from recipients of long-term functioning (more than 60 months) biological and mechanical heart valve prostheses. …”
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4512por Chen, Hao, Lau, Mai Chan, Wong, Michael Thomas, Newell, Evan W., Poidinger, Michael, Chen, Jinmiao“…Cytofkit provides functions for data pre-processing, data visualization through linear or non-linear dimensionality reduction, automatic identification of cell subsets, and inference of the relatedness between cell subsets. …”
Publicado 2016
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4513por Landsverk, Ole J.B., Snir, Omri, Casado, Raquel Bartolomé, Richter, Lisa, Mold, Jeff E., Réu, Pedro, Horneland, Rune, Paulsen, Vemund, Yaqub, Sheraz, Aandahl, Einar Martin, Øyen, Ole M., Thorarensen, Hildur Sif, Salehpour, Mehran, Possnert, Göran, Frisén, Jonas, Sollid, Ludvig M., Baekkevold, Espen S., Jahnsen, Frode L.“…We identified three distinct PC subsets: a CD19(+) PC subset was dynamically exchanged, whereas of two CD19(−) PC subsets, CD45(+) PCs exhibited little and CD45(−) PCs no replacement and had a median age of 11 and 22 yr, respectively. …”
Publicado 2017
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4514por Hasan, Zafrul, Koizumi, Shin-ichi, Sasaki, Daiki, Yamada, Hayato, Arakaki, Nana, Fujihara, Yoshitaka, Okitsu, Shiho, Shirahata, Hiroki, Ishikawa, Hiroki“…CD4(+) T-helper cells producing interleukin-17 (IL-17), known as T-helper 17 (T(H)17) cells, comprise heterogeneous subsets that exhibit distinct pathogenicity. Although pathogenic and non-pathogenic T(H)17 subsets share a common RORγt-dependent T(H)17 transcriptional programme, transcriptional regulatory mechanisms specific to each of these subsets are mostly unknown. …”
Publicado 2017
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4515“…The recent observations that Tregs can polarize into distinct lineages similar to the Th1, Th2, and Th17 subsets described for conventional T helper cells raise the possibility that Th1-, Th2-, and Th17-driven pathology may require matching Treg subsets for optimal therapeutic efficacy. …”
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4516por Sano, Haruo, Sato, Soichiro, Shima, Junko, Tada, Tsuyoshi, Fujiwara, Hiromi, Hamaoka, Toshiyuki“…However, in contrast to comparable tumor‐neutralization by Lyt‐2(+) and L3T4(+) T subsets from hyperimmune mice, only the Lyt‐2(+) T cell subset from tumor‐bearing mice was capable of mediating the in vivo protective immunity. …”
Publicado 1988
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4517“…In the B cell compartment, several subsets engage in both adaptive and innate functions. …”
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4518“…During immune responses, T cells differentiate into subsets with different functions and migratory properties. …”
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4519Publicado 2010“…METHODS: The nucleated cell amounts of advanced lung cancer patients and the healthy individuals were counted. The immune cell subsets and the levels of IL-4, INF-γ, perforin and granzyme in CD8(+)T cells by the flow cytometry were measured. …”
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4520“…Although such subsets are rarely identified in autoimmune diseases, some unique subsets of neutrophils, including low density granulocytes (LDGs) and CD177(+) neutrophils, have been reported. …”
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