“…A methylation dataset is divided into subsets, where each subset contains only the probes that relate to a known gene pathway. …”
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“…METHODS: We either stimulated purified B cells from AID‐green fluorescence protein (GFP) reporter mice or infected AID‐GFP mice with Plasmodium chabaudi, AID fluorescence was monitored in B cell subsets by flow cytometry. RESULTS: In vitro analysis of B cells from these mice revealed that CpG (a Toll‐like receptor 9 ligand) was a potent inducer of AID in both mature and immature B cell subsets. …”
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“…By investigating the effect of IL-17 in the number and distribution of lymphocyte infiltration in tumor tissues, the expression of cytokines and transcription factors associated with the subsets of CD4(+)T cells in tumor tissues, the distribution of subsets of spleen lymphocyte in tumor-bearing mice, a preliminary investigation of the possible antitumor mechanism of IL-17 was performed. …”
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“…Myelopoiesis was further investigated by way of particular subsets affected. A specific question addressed whether booreana mice contained increased numbers of dendritic-like cells (L-DC subset) recently identified in the spleen, since L-DCs arise in vitro by direct differentiation from HSPCs co-cultured over splenic stroma. …”
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“…Cytobrush-derived T cell and dendritic cell subsets were assessed by multiparameter flow cytometry. …”
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“…For example, when partitioning the data into 20 clock-subsets based on patterns of among-lineage rate heterogeneity, we inferred crown angiosperms to have arisen 198–178 Ma. …”
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“…In this hypothesis generating study, the immunological alterations in circulating immune subsets induced by everolimus included a (non-significant) increase in the frequency of Tregs, a significant increase in monocytic myeloid-derived suppressor cells, a significant decrease in the frequency of immunoregulatory natural killer cells, classical CD141(+) (cDC1) and CD1c(+) (cDC2) dendritic cell subsets, as well as a decrease in the activation status of plasmacytoid dendritic cells and cDC1. …”
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“…Accumulating evidence indicates the importance of natural killer (NK) cells in controlling tumor growth and metastasis. NK cell subsets display diversities in their function and tissue distribution and Mac‐1(hi) CD27(lo) NK cells are the predominant population of lung‐resident NK cells. …”
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“…Given a collection [Formula: see text] of subsets of a finite set X, we say that [Formula: see text] is phylogenetically flexible if, for any collection R of rooted phylogenetic trees whose leaf sets comprise the collection [Formula: see text] , R is compatible (i.e. there is a rooted phylogenetic X-tree that displays each tree in R). …”
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“…However, specific immune cell subsets delineated by the manual gating of continuous variables were not fully separated in t-SNE space thus causing discrepancies in subset identification and quantification between these analytical approaches. …”
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“…We found that the landscape of CD4 T cell subsets differs markedly between young and old mice, such that three cell subsets—exhausted, cytotoxic, and activated regulatory T cells (aT(regs))—appear rarely in young mice but gradually accumulate with age. …”
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“…In terms of the results of the classification, the performance of feature subsets selected from sWGFC was better than sGFC, and the performance of feature subsets selected from dWGFC was better than dGFC. …”
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“…In the present study, the percentage of CD4(+) T-cell subsets and related cytokines was measured using flow cytometry and an enzyme-linked immunosorbent assay. …”
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“…Here, we characterized human B cell subsets, their production of IL-10 in patients with atherosclerosis and their potential association with inflammation. …”
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“…We further present two applications of FB5P-seq for the analysis of human tonsil B cell subsets and peripheral blood antigen-specific CD4 T cells. …”
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“…Here, we explored the transcriptome of circulating human ILC subsets as opposed to CD4 Th cell subsets. We describe transcriptomic differences between total ILCs and total CD4 Th cells, as well as between paired innate and adaptive cell subsets (ILC1 vs. …”
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“…Significant differences were detected in the expression of histone genes affecting all iNKT subsets. Also the proliferative capacity of iNKT cells decreased substantially upon aging. …”
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“…We observed significant changes in T cells and subsets, NK and B cells (CD4(+), CD8(+), CD4(+)/CD8(+), CD16(+), and CD20(+)). …”
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“…In this study, we sought to identify detailed subsets of anti-viral CD8(+) T cell immunity linked to natural long-term control of HIV-1 infection. …”
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“…The influence of steroids on multiple immune cells subsets will also be discussed.…”
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