“…We also highlight the functional characteristics of human DC subsets in inflammatory skin environments and skin diseases including psoriasis and atopic dermatitis. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…This review will provide an overview of Vitamin D metabolism, a description of dendritic cell subsets, and highlight recent advances on the effects of vitamin D on dendritic cell function, maturation, cytokine production and antigen presentation. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…In this review, we describe the different Breg subsets identified in mice and humans, and their diverse mechanisms of suppression in different disease settings.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…A number of both genetic and environmental mechanisms may allow such immune escape, including selection of poorly antigenic cancer cell subsets, tumor produced proinflammatory and immunosuppressive cytokines, recruitment of immunosuppressive immune cell subsets into the tumor and expression of checkpoint pathway components that limit T-cell responses. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Additionally, recent evidence indicates that Tregs comprise diverse and heterogeneous subsets; phenotypically and functionally distinct subsets of tumor-infiltrating Tregs could contribute differently to cancer prognosis and clinical outcomes. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The transcription factor NKX2-1 is best known for its role in the specification of subsets of cortical, striatal, and pallidal neurons. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…These cells undergo activation, proliferation and differentiation into various subsets. During these processes they initiate metabolic reprogramming, which is coordinated by specific gene and protein activities. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…We discuss here how Treg cell subsets can be differentiated phenotypically, functionally and developmentally in humans.…”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Numerous studies have examined the presence and changes of different T cell subsets, including helper T cells, regulatory T cells, cytotoxic T cells, and natural killer T cells, in adipose depots in health and diseases. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The first phase uses a multiobjective evolutionary technique to perform the selection of subsets of descriptors. The second phase performs an external validation of the chosen descriptors subsets in order to improve reliability. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Treg cells consist of heterogeneous subsets that have distinct phenotypes and functions. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…The methodology applied in this paper has two steps: first, alternative subsets of molecular descriptors useful for characterizing LRRK2 inhibitors are chosen by a multi-objective feature selection method; secondly, QSAR models are learned by using these subsets and three different strategies for supervised learning. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Comparison of B cell subsets from the peripheral blood and salivary glands of patients with primary Sjögren’s syndrome and those from healthy individuals shows dysregulation and derangement of B cell subsets in both peripheral circulation and in inflamed glandular tissues. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Insights gained about the cytokine dysregulation in SLE have the potential for identifying patient subsets before the onset of clinical disease and during established disease. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Recent studies suggest that murine invariant natural killer T (iNKT) cell development culminates in three terminally differentiated iNKT cell subsets denoted as NKT1, 2, and 17 cells. Although these studies corroborate the significance of the subset division model, less is known about the factors driving subset commitment in iNKT cell progenitors. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Biclustering, the discovery of coherent concept associations (subsets of documents correlated on subsets of terms and topics), is here suggested to address the aforementioned problems. …”
Enlace del recurso
Enlace del recurso

“…First, we set two thresholds based on probabilistic analysis to construct and further filter the cluster subsets. Then, we use Affinity Propagation (AP) clustering on the candidate cluster subsets to find the potential motifs. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Human dendritic cells (DCs) comprise subsets with distinct phenotypic and functional characteristics, but the transcriptional programs that dictate their identity remain elusive. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Analysis reveals seven distinct TPC subpopulations including subsets that are responsive to the mechanical stress, highly clonogenic, and specialized in cytokine or growth factor expression. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso

“…Monocytes are, however, heterogeneous differentiating from classical monocytes through the intermediate subset to the nonclassical subset. While it is recognized that the percentage of intermediate and nonclassical monocytes are higher in individuals with CVD, accompanying changes in inflammatory markers suggest a functional impact on disease development that goes beyond the increased proportion of these ‘inflammatory’ monocyte subsets. …”
Enlace del recurso
Enlace del recurso
Enlace del recurso