“…Type-2 immunity is regulated by two distinct CD4+ T cell subsets. T follicular helper (Tfh) cells are required for humoral hallmarks of type-2 inflammation. …”
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“…Endoplasmic reticulum (ER) stress responses, which link metabolism to transcriptional outcomes, were similar between long- and short-lived subsets. Accordingly, population and single-cell transcriptional comparisons across mouse and human plasma cell subsets revealed few consistent and conserved differences. …”
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“…Over the past several years, a number of T-cell subsets have been identified. One of these T-cell subsets are the T-regulatory (T(reg)) cells. …”
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“…We also define somatic cell subsets in both neonatal and adult testes and trace their developmental trajectories. …”
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“…These divergent functions arise due to the diversity of T cell subsets, particularly CD4(+) T cells. Here, we review the beneficial impact of T cell subsets in a range of neuroinflammatory and neurodegenerative diseases including multiple sclerosis, Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, stroke, and CNS trauma. …”
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“…We provide a unique method, which enables the molecular characterization of clinically relevant CTC subsets, as well as circulating tumor DNA (ctDNA), from a single blood sample. …”
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“…Here, we tracked the generation of memory CD4(+) T cell subsets in mice housed in facilities differing in their ‘dirtiness’. …”
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“…The influence of c-Maf is particularly prominent among T cell subsets, where c-Maf regulates the differentiation as well as the function of multiple subsets of CD4 and CD8 T cells, lending it a crucial position in adaptive immunity and anti-tumoral responsiveness. …”
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“…Different from the previous methods which use mutual information and greedy iteration with a loss function to rank the features, we rank features according to their distribution similarities in two classes measured by relative entropy, and then remove the high redundant features from the sorted feature subsets. Experimental results on datasets in varieties of fields with different classifiers highlight the value of mDSRR on selecting feature subsets, especially so for choosing small size feature subset. mDSRR is also proved to outperform other state-of-the-art methods in most cases. …”
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“…The analyses of these cell subsets in peripheral blood, as a more accessible and homogeneous sample, might facilitate clinical decisions concerning fast prediction of ICI efficacy. …”
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“…These responses, whether they represent mechanistic or non-mechanistic immunological correlates ofprotection, usually entail the activation ofT cell memory and effector subsets (T-CMI) and induction of long-lasting memory B cells. …”
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“…In this review, we discuss the composition and renewal of various subsets of CRMs. Specific attention has been given to delineate the roles of various CRM subsets with respect to (1) facilitation of cardiac development and maintenance of physiological function such as electrical conduction and rhythm; (2) promotion of cardiac regeneration, inflammation resolution and functional remodelling following a cardiac injury; and (3) therapeutic potential. …”
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“…Social-ON cells included those that represented social investigation independent of location and consisted of multiple subsets, each of which was preferentially active during exploration under a particular behavioral state or with a particular target of physical contact. …”
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“…Then, using a greedy approach, the most informative subsets are selected in an iterative way. The algorithm terminates, when the highest ranked variable is not able to significantly improve the accuracy of the prediction as compared to that obtained using the existing selected subsets. …”
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“…Systemic and local factors influencing metabolism alter HSCs balance under pathological conditions, with chronic metabolic and inflammatory diseases driving HSCs commitment toward activated blood immune cell subsets. This is the case of atherosclerosis, where impaired systemic lipid metabolism affects HSCs epigenetics that reflects into increased differentiation toward activated circulating subsets. …”
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“…DC subsets can be classified into conventional, plasmacytoid, and monocyte-derived DC in the tumor microenvironment, and each subset plays a different role. …”
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“…These microenvironments are classically defined as distinct cortex and medulla regions that each contain specialized subsets of stromal cells. Extensive research on thymic epithelial cells (TEC) within the cortex and medulla has defined their essential roles during T-cell development. …”
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“…In response to infection, T cells adopt a range of differentiation states, creating numerous heterogeneous subsets that exhibit different phenotypes, functions, and migration patterns. …”
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“…MSCs can regulate T cell subsets to restore their immune homeostasis toward disease resolution in autoimmune conditions. …”
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“…The results reveal that some subsets of coefficients consistently group together regardless of the base rates. …”
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