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1421“…As such, we utilized conditioned medium from bone marrow-derived MSCs (MSC-CM) and studied its effect on different macrophage subsets. Effects on macrophage proliferation, apoptosis, polarization, and phagocytosis were determined, and it was discovered that MSC-CM had no significant effect on macrophage proliferation but inhibited M0 macrophage apoptosis and marginally induced M1 macrophage apoptosis. …”
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1422por Comeault, Aaron A., Serrato‐Capuchina, Antonio, Turissini, David A., McLaughlin, Patrick J., David, Jean R., Matute, Daniel R.“…We then show that a nonrandom subset of genes controlling olfaction‐–those controlling odorant‐binding and chemosensory proteins–‐have an enriched signature of positive selection relative to the rest of the D. orena genome. …”
Publicado 2017
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1424por Pezoldt, Joern, Pasztoi, Maria, Zou, Mangge, Wiechers, Carolin, Beckstette, Michael, Thierry, Guilhem R., Vafadarnejad, Ehsan, Floess, Stefan, Arampatzi, Panagiota, Buettner, Manuela, Schweer, Janina, Fleissner, Diana, Vital, Marius, Pieper, Dietmar H., Basic, Marijana, Dersch, Petra, Strowig, Till, Hornef, Mathias, Bleich, André, Bode, Ulrike, Pabst, Oliver, Bajénoff, Marc, Saliba, Antoine-Emmanuel, Huehn, Jochen“…LN transplantation and single-cell RNA-seq uncover stably imprinted expression signatures in mLN fibroblastic stromal cells. Subsetting common stromal cells across gut-draining mLNs and skin-draining LNs further refine their location-specific immunomodulatory functions, such as subset-specific expression of Aldh1a2/3. …”
Publicado 2018
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1425por Rijkers, Maaike, Saris, Anno, Heidt, Sebastiaan, Mulder, Arend, Porcelijn, Leendert, Claas, Frans H.J., Bierings, Ruben, Leebeek, Frank W.G., Jansen, A.J. Gerard, Vidarsson, Gestur, Voorberg, Jan, de Haas, Masja“…Our data show that a subset of HLA antibodies is capable of crosslinking HLA and FcγRIIa thereby promoting platelet activation and enhancing these cells’ phagocytosis by macrophages. …”
Publicado 2018
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1426por Liu, Weiwei, Zhang, Yajie, Zhu, Weina, Ma, Chunhua, Ruan, Jie, Long, Hongyan, Wang, Yue“…To explore the mechanism of SIN anti-inflammatory function, RA-associated monocyte/macrophage subsets were determined using flow cytometry in CIA mouse model and RA patients, both treated with SIN. …”
Publicado 2018
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1427“…An ELISA method was employed to detect the TgAb level (thyroid inflammation) in the serum of the EAT mice. The T cell subsets in peripheral blood and spleen were detected by flow cytometry. …”
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1428por Richards, Amanda L., Sheldon, Kathryn, Wu, Xiaoping, Gruber, David R., Hudson, Krystalyn E.“…Conclusions: These data demonstrate that regardless of the ability to participate in RBC consumption, only a subset of APCs are capable of forming an immune synapse with T cells thereby initiating an alloantibody response. …”
Publicado 2018
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1429por Chen, Yu, Lin, Wei, Yang, Hongxian, Wang, Mu, Zhang, Panpan, Feng, Ruie, Chen, Hua, Peng, Linyi, Zhang, Xuan, Zhao, Yan, Zeng, Xiaofeng, Zhang, Fengchun, Zhang, Wen, Lipsky, Peter E.“…OBJECTIVE: To determine the number and function of follicular helper T (Tfh) cell subsets in IgG4‐related disease (IgG4‐RD). METHODS: Mononuclear cells from the peripheral blood and involved tissue of patients with IgG4‐RD were assessed for Tfh cells and their subsets, and levels of B cell lymphoma 6 (Bcl‐6), B lymphocyte–induced maturation protein 1 (BLIMP‐1), and interleukin‐21 (IL‐21) messenger RNA (mRNA). …”
Publicado 2018
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1430“…We searched this, and other newly available sequence datasets, for CD4+ T cell subset-defining genes, aiming to confirm the presence or absence of each subset in cartilaginous fishes. …”
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1431por Lund, Harald, Pieber, Melanie, Parsa, Roham, Han, Jinming, Grommisch, David, Ewing, Ewoud, Kular, Lara, Needhamsen, Maria, Espinosa, Alexander, Nilsson, Emma, Överby, Anna K., Butovsky, Oleg, Jagodic, Maja, Zhang, Xing-Mei, Harris, Robert A.Enlace del recurso
Publicado 2018
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1432por Aulicino, Anna, Rue-Albrecht, Kevin C., Preciado-Llanes, Lorena, Napolitani, Giorgio, Ashley, Neil, Cribbs, Adam, Koth, Jana, Lagerholm, B. Christoffer, Ambrose, Tim, Gordon, Melita A., Sims, David, Simmons, AlisonEnlace del recurso
Publicado 2018
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1433por Salou, Marion, Legoux, François, Gilet, Jules, Darbois, Aurélie, du Halgouet, Anastasia, Alonso, Ruby, Richer, Wilfrid, Goubet, Anne-Gaëlle, Daviaud, Céline, Menger, Laurie, Procopio, Emanuele, Premel, Virginie, Lantz, Olivier“…MAIT1 (RORγt(neg)) and MAIT17 (RORγt(+)) subsets were markedly distinct from mainstream T cells, but quasi-identical to NKT1 and NKT17 subsets. …”
Publicado 2019
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1434por Zhang, Ying, Cao, Rong, Ying, Haijian, Du, Juping, Chen, Shuaishuai, Wang, Na, Shen, Bo“…Compared to that in the HCs, TLR10 was elevated significantly in the CD19(+)CD27(−)IgD(−) and CD19(+)CD5(+) subsets in the RA subjects. In addition, almost all subsets expressing TLR10 were increased with disease activity. …”
Publicado 2018
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1435por Reyes, Miguel, Vickers, Dwayne, Billman, Kianna, Eisenhaure, Thomas, Hoover, Paul, Browne, Edward P., Rao, Deepak A., Hacohen, Nir, Blainey, Paul C.“…However, subset-specific responses may not be detectable in analyses of whole blood samples, and no efficient approach for profiling cell subsets at high throughput from small samples is available. …”
Publicado 2019
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1436por Le Goff, Maëlle, Cornec, Divi, Guellec, Dewi, Marhadour, Thierry, Devauchelle-Pensec, Valérie, Jousse-Joulin, Sandrine, Herbette, Marion, Cauvin, Jean Michel, Le Guillou, Clara, Renaudineau, Yves, Jamin, Christophe, Pers, Jacques Olivier, Saraux, Alain“…OBJECTIVE: To look for abnormalities in circulating B-cell subsets in patients with rheumatic symptoms of Whipple’s disease (WD). …”
Publicado 2019
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1437“…The experimental results indicate that distinct Nrf1 isoforms make diverse and even opposing contributions to regulating different subsets of target genes, such as those encoding 26S proteasomal subunits and others involved in various biological processes and functions. …”
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1438por Fukamachi, Hiroshi, Kim, Seon-Kyu, Koh, Jiwon, Lee, Hye Seung, Sasaki, Yasushi, Yamashita, Kentaro, Nishikawaji, Taketo, Shimada, Shu, Akiyama, Yoshimitsu, Byeon, Sun-ju, Bae, Dong-Hyuck, Okuno, Keisuke, Nakagawa, Masatoshi, Tanioka, Toshiro, Inokuchi, Mikito, Kawachi, Hiroshi, Tsuchiya, Kiichiro, Kojima, Kazuyuki, Tokino, Takashi, Eishi, Yoshinobu, Kim, Yong Sung, Kim, Woo Ho, Yuasa, Yasuhito, Tanaka, Shinji“…CONCLUSION: mTOR inhibitors and checkpoint inhibitors might be useful for the treatment of a subset of diffuse-type GCs which may develop from intestinal-type GCs. …”
Publicado 2019
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1439por Russo, Marc A., Fiore, Nathan T., van Vreden, Caryn, Bailey, Dominic, Santarelli, Danielle M., McGuire, Helen M., Fazekas de St Groth, Barbara, Austin, Paul J.Enlace del recurso
Publicado 2019
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1440por Ramos, Paula S., Zimmerman, Kip D., Haddad, Sandra, Langefeld, Carl D., Medsger, Thomas A., Feghali-Bostwick, Carol A.Enlace del recurso
Publicado 2019
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