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  1. 17841
    “…Five participants (12%) reported suicidal ideation; none resulted in discontinuation. …”
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    Effectiveness and Safety of Bictegravir/Emtricitabine/Tenofovir Alafenamide in Patients With HIV-1 Infection and Ongoing Substance Use Disorder: The BASE Study
  2. 17842
    “…Assessments will be completed at baseline, 6 weeks and 12 weeks with the primary outcome being improvement in clinician-rated and self-reported depressive severity (Children’s Depression Rating Scale—Revised and PHQ-9) and secondary outcomes being self-reported suicidal ideation (item 9 on PHQ-9), anxiety severity (Generalised Anxiety Disorder), general quality of life (Satisfaction with Life Scale) and general functioning (Children’s Global Assessment Scale). …”
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    Efficacy of a digital mental health intervention embedded in routine care compared with treatment as usual in adolescents and young adults with moderate depressive symptoms: protocol for randomised controlled trial
  3. 17843
    “…The presence of a mental or substance abuse disorder is behind a significant percentage of suicidal behaviors in Mexico, where only 1 in 5 of those who have these disorders receive any treatment. …”
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    A Computational Platform to Support the Detection, Follow-up, and Epidemiological Surveillance of Mental Health and Substance Use Disorders: Protocol for a Development and Evaluation Study
  4. 17844
    “…RESULTS: Stage 1 highlighted nine key design principles (plus 25 subthemes) that participants emphasised as important to ensure the website would have broad appeal and meet their needs: (1) user choice is valued highly; (2) ACT-based content is acceptable as it is focused on helping people be proactive and ‘get unstuck’; (3) non-pathologising, direct, empowering, lay language is endorsed; (4) a positive look and feel is appreciated; (5) images and videos are important to break up text and maintain engagement; (6) short text messages to aid engagement are valued; (7) provision of tailored psychoeducation for highly distressed and suicidal users is endorsed; (8) personal and proactive brand name is preferred (icanactnow); (9) diverse marketing and training activities are recommended. …”
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    What consumers, general practitioners and mental health professionals want: the co-design and prototype testing of a transdiagnostic, acceptance and commitment therapy-based online intervention to reduce distress and promote wellbeing among Australian adults
  5. 17845
    por Chen, Jing, Cai, Yiyun, Cong, Enzhao, Liu, Ying, Gao, Jingfang, Li, Youhui, Tao, Ming, Zhang, Kerang, Wang, Xumei, Gao, Chengge, Yang, Lijun, Li, Kan, Shi, Jianguo, Wang, Gang, Liu, Lanfen, Zhang, Jinbei, Du, Bo, Jiang, Guoqing, Shen, Jianhua, Zhang, Zhen, Liang, Wei, Sun, Jing, Hu, Jian, Liu, Tiebang, Wang, Xueyi, Miao, Guodong, Meng, Huaqing, Li, Yi, Hu, Chunmei, Li, Yi, Huang, Guoping, Li, Gongying, Ha, Baowei, Deng, Hong, Mei, Qiyi, Zhong, Hui, Gao, Shugui, Sang, Hong, Zhang, Yutang, Fang, Xiang, Yu, Fengyu, Yang, Donglin, Liu, Tieqiao, Chen, Yunchun, Hong, Xiaohong, Wu, Wenyuan, Chen, Guibing, Cai, Min, Song, Yan, Pan, Jiyang, Dong, Jicheng, Pan, Runde, Zhang, Wei, Shen, Zhenming, Liu, Zhengrong, Gu, Danhua, Wang, Xiaoping, Liu, Xiaojuan, Zhang, Qiwen, Li, Yihan, Chen, Yiping, Kendler, Kenneth S., Shi, Shenxun, Flint, Jonathan
    Publicado 2014
    “…Any form of CSA was significantly associated with suicidal ideation or attempt (OR 1.50, 95% CI 1.20–1.89) and feelings of worthlessness or guilt (OR 1.41, 95% CI 1.02–2.02). …”
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    Childhood Sexual Abuse and the Development of Recurrent Major Depression in Chinese Women
  6. 17846
    “…Secondary outcomes include severity of disorder and remission rates at 12 months, disability scores, suicidal behaviour and economic impact, and cost-effectiveness at three and 12 months. 500 participants with depression and 400 participants with harmful drinking will be recruited. …”
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    The effectiveness and cost-effectiveness of lay counsellor-delivered psychological treatments for harmful and dependent drinking and moderate to severe depression in primary care in India: PREMIUM study protocol for randomized controlled trials
  7. 17847
    “…The prevalence of moderate or severe depression symptomatology among men and suicidal thoughts decreased significantly (p < 0.0001 and p = 0.01). …”
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    Stepping Stones and Creating Futures intervention: shortened interrupted time series evaluation of a behavioural and structural health promotion and violence prevention intervention for young people in informal settlements in Durban, South Africa
  8. 17848
    “…BACKGROUND: People with borderline personality disorder (BPD) experience rapid and distressing changes in mood, poor social functioning and have high rates of suicidal behaviour. Several small scale studies suggest that mood stabilizers may produce short-term reductions in symptoms of BPD, but have not been large enough to fully examine clinical and cost-effectiveness. …”
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    Lamotrigine versus inert placebo in the treatment of borderline personality disorder: study protocol for a randomized controlled trial and economic evaluation
  9. 17849
    “…The primary outcome will be symptoms of depression, and secondary outcomes will include symptoms of anxiety, suicidal ideation and behaviours, stigma and academic performance. …”
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    Trial for the Prevention of Depression (TriPoD) in final-year secondary students: study protocol for a cluster randomised controlled trial
  10. 17850
    “…The investigation aims to determine if intervention patients demonstrate significant reductions in PTSD and depressive symptoms, suicidal ideation, alcohol consumption, and improvements in physical function when compared to control patients. …”
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    An effectiveness-implementation hybrid trial study protocol targeting posttraumatic stress disorder and comorbidity
  11. 17851
    “…Patients with psychosis or type I/II bipolar disorder, actively suicidal, in receipt of services for substance misuse, or already in receipt of psychological therapy for depression were excluded. …”
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    Long-term cost-effectiveness of collaborative care (vs usual care) for people with depression and comorbid diabetes or cardiovascular disease: a Markov model informed by the COINCIDE randomised controlled trial
  12. 17852
    “…Heavy Poly-Users were more likely to engage in other substance use behaviors, report suicidal ideation, and report being bullied because of gender. …”
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    Patterns and Profiles of Adolescent Tobacco Users: Results From the Virginia Youth Survey
  13. 17853
    “…Secondary outcomes include real world distress, activity levels, suicidal ideation, and quality of life. Mediation will also be tested. …”
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    Automated psychological therapy using virtual reality (VR) for patients with persecutory delusions: study protocol for a single-blind parallel-group randomised controlled trial (THRIVE)
  14. 17854
    “…Secondary measures include weekly assessment of methamphetamine craving, severity of methamphetamine dependence, methamphetamine withdrawal symptoms and psychiatric symptoms (depression, suicidality, psychotic symptoms and hostility). Adverse events are monitored at each weekly assessment. …”
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    A study protocol for the N-ICE trial: A randomised double-blind placebo-controlled study of the safety and efficacy of N-acetyl-cysteine (NAC) as a pharmacotherapy for methamphetamine (“ice”) dependence
  15. 17855
    “…The survey contained demographic questions, depression, anxiety, and suicidality screeners, and questions about their use of offline resources (eg, parents, peers, and counselors) and Web-based resources (ie, telemental health technologies) when they faced stressful life situations. …”
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    Audience Response Systems and Missingness Trends: Using Interactive Polling Systems to Gather Sensitive Health Information From Youth
  16. 17856
    “…Secondary outcomes include other substance use and related problems, PE-related distress, cannabis intoxication experiences, severity of cannabis dependence, depression/anxiety symptoms, suicidality, and mental well-being and functioning. …”
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    A Web-Based Program for Cannabis Use and Psychotic Experiences in Young People (Keep It Real): Protocol for a Randomized Controlled Trial
  17. 17857
    “…Patients with mental disorders (MD) including substance use disorders (SUD) and suicidal behaviors are high ED users. Improving ED services for these patients and their families, and developing alternatives to ED use are thus key issues. …”
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    Implementation of three innovative interventions in a psychiatric emergency department aimed at improving service use: a mixed-method study
  18. 17858
    “…METHODS: A two-arm parallel randomized controlled trial is conducted in a target sample of 285 non-suicidal Hong Kong Chinese older than 17 years of age with major depression and insomnia. …”
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    Treating depression with a smartphone-delivered self-help cognitive behavioral therapy for insomnia: study protocol for a parallel group randomized controlled trial
  19. 17859
    “…Mental health indicators including psychological and severe psychological distress, life satisfaction, vitality, eating disorders, suicidal ideation, subjective health and depressive and anxiety disorders, demographics and health behavior such as smoking are derived from the BHIS. …”
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    Environmental exposures and health behavior in association with mental health: a study design
  20. 17860
    “…Outcomes of interest are symptoms of depression, classification of major depressive disorder based on a validated diagnostic interview, suicidality, health-related quality of life, social function, impact on lifestyle behavior (e.g., substance use, school performance, lost time at work, or school), false-positive results, overdiagnosis, overtreatment, labeling, and other harms such as those arising from treatment. …”
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    Screening for depression in children and adolescents: a protocol for a systematic review update
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