“…In the present work, our aim was to further explore the implications of protein dynamics on β-lactamase function by altering the dynamic profile of TEM-1 using computational protein design methods. The Rosetta software suite was used to mutate amino acids surrounding either rigid residues that are highly coupled to the active site or to flexible residues with no apparent communication with the active site. …”
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“…This study compared the effects of a 21-day exposure to 1.5, 15, and 150 ng/L of polystyrene microplastics (PS-MP, 3-µm) and nanoplastics (PS-NP, 50-nm) on a suite of biomarkers measured in the Mediterranean mussel Mytilus galloprovincialis. …”
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“…The complex nature of these communities requires further study across a broader suite of patients in addition to higher resolution analyses including metagenomics to better assess the fundamental role of microorganisms in capsular contracture.…”
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“…Specifically, we propose to use the special characteristics of historical activity of residents in a multi-person environment, including activity interaction, activity frequency, activity period length, and residential behaviors, and then apply a suite of machine learning methods to train and test. …”
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“…To understand the effect of ACE2 missense variants on protein structure, stability, and function, various bioinformatics tools were used including SIFT, PANTHER, PROVEAN, PolyPhen2.0, I. Mutant Suite, MUpro, SWISS-MODEL, Project HOPE, ModPred, QMEAN, ConSurf, and STRING. …”
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“…The mechanisms of endocrine disruption involve a complex system of pathways that communicate across the body to stimulate specific receptors that bind DNA and regulate the expression of a suite of genes. These mechanisms, including gene regulation, DNA binding, and protein binding, can be tied to differences in individual susceptibility across a genetically diverse population. …”
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“…These plutonic rocks are thought to correspond to the Dinhquan suite in southern Vietnam. The Kon Mom and Koh Nheak plutonic rocks fall within the alkaline series, which suggests that the magma genesis was deep and far from the western Paleo-Pacific Ocean plate. …”
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“…This demonstrates that onomatopoeia may be reliably used to classify bird calls by non-expert listeners, adding to the suite of methods used in classification of biological sounds. …”
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“…We recommend that future plankton ecosystem models pay particular attention to the grazing formulation and implement a threshold refuge incorporating size-dependence, and we call for a new suite of experimental grazing studies.…”
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“…Our strategy for the data analysis combines two software packages, ProSight PD (PS) and TopPIC suite (TP), with a clustering algorithm to decipher protamine proteoforms. …”
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“…Here, we integrate data from a suite of well-studied species with a global dataset of bird occurrences throughout the world—for 9,700 species (∼92% of all extant species)—and use missing data theory to estimate species-specific abundances with associated uncertainty. …”
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“…This plasticity was demonstrated in the large variation recorded throughout a suite of bioindicators measured within Zostera marina meadows around Wales and SW England, United Kingdom. …”
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“…The manufactured devices adopt micro-electro-mechanical (MEMS) digital sensor technology for recording acceleration, whereas the accompanying software suite provides various configuration options, quick browsing, analyzing and exporting of the recorded events, as well as GIS type functionality for seamlessly producing explicit seismic hazard maps of the considered area. …”
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“…We report a new method to optically manipulate a single dielectric particle along closed-loop polygonal trajectories by crossing a suite of all-fiber Bessel-like beams within a single water droplet. …”
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“…Evaluation of the resulting bit streams’ randomness by the NIST statistical test suite highlights the importance of evaluating the physical entropy content, as bit sequences generated by this random laser pass all the statistical tests with a significance level of 0.01, despite being generated at more than twice the theoretical entropy generation speed.…”
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“…In this study, we apply zooarchaeology by mass spectrometry (ZooMS) and liquid chromatography tandem mass spectrometry to dog palaeofaeces to investigate protein preservation in this highly degradable material and obtain information about the diet of domestic dogs at the Nunalleq site, Alaska. We identify a suite of digestive and metabolic proteins from the host species, demonstrating the utility of this material as a novel and viable substrate for the recovery of gastrointestinal proteomes. …”
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“…As in our previous studies, the large and chemically diverse GMTKN55 benchmark suite was used for evaluation. Especially when using the D4 rather than D3BJ dispersion model, xDSD has a slight performance advantage in WTMAD2. …”
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“…The Cognitive Performance Scale (CPS) in the widely used interRAI suite of instruments is of interest to clinicians and policy makers as a potential screening mechanism for detecting dementia. …”
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“…Our BART models included, as predictors, a large suite of land-use variables, meteorological conditions, satellite-derived aerosol optical depth parameters, and simulations from a chemical transport model. …”
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“…Our evaluations across a suite of benchmark SNNs demonstrate that probabilistic spike propagation results in 1.39–2× energy reduction with simultaneous speedups of 1.16–1.62× compared to the traditional model of SNN evaluation.…”
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