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4621por Carley, Lauren N., Mojica, Julius P., Wang, Baosheng, Chen, Chia-Yu, Lin, Ya-Ping, Prasad, Kasavajhala V. S. K., Chan, Emily, Hsu, Che-Wei, Keith, Rose, Nuñez, Chase L., Olson-Manning, Carrie F., Rushworth, Catherine A., Wagner, Maggie R., Wang, Jing, Yeh, Pei-Min, Reichelt, Michael, Ghattas, Kathryn, Gershenzon, Jonathan, Lee, Cheng-Ruei, Mitchell-Olds, Thomas“…We investigated mechanisms that may maintain variation in a focal polymorphism—leaf chemical profiles of a perennial wildflower (Boechera stricta, Brassicaceae)—explicitly interrogating multiple ecological and genetic processes including spatial variation in selection, antagonistic pleiotropy, and frequency-dependent selection. A suite of common garden and greenhouse experiments showed that the alleles underlying variation in chemical profile have contrasting fitness effects across environments, implicating two ecological drivers of selection on chemical profile: herbivory and drought. …”
Publicado 2021
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4622por Yang, Siyun, Lorenzi, Elizabeth, Papadogeorgou, Georgia, Wojdyla, Daniel M., Li, Fan, Thomas, Laine E.“…In this article, we develop a suite of analytical methods and visualization tools for causal SGA. …”
Publicado 2021
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4623“…Coupling LRS with technologies such as single cell sequencing, targeted sequencing and spatial transcriptomics is producing a rapidly expanding suite of technological approaches to profile alternative splicing at the isoform level with unprecedented detail. …”
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4624“…The method is demonstrated on a suite of ~50 to 90 Myrs (million years) old celadonite samples that are dated with age uncertainties typically of ±2 to 5 Myrs provided the sample Rb/Sr is >2. …”
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4625Modular and Molecular Optimization of a LOV (Light–Oxygen–Voltage)-Based Optogenetic Switch in Yeastpor Romero, Andrés, Rojas, Vicente, Delgado, Verónica, Salinas, Francisco, Larrondo, Luis F.“…Altogether, we describe a new set of blue-light optogenetic switches carrying different protein modules, which expands the available suite of optogenetic tools in yeast and can additionally be applied to other systems.…”
Publicado 2021
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4626por Ciesielski, Grzegorz L., Kim, Shalom, de Bovi Pontes, Carolina, Kaguni, Laurie S.“…The maintenance of the mitochondrial genome depends on a suite of nucleus-encoded proteins, among which the catalytic subunit of the mitochondrial replicative DNA polymerase, Pol γα, plays a pivotal role. …”
Publicado 2021
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4627“…A second compound, 2-(2-hydroxyethoxy)ethylguanidine succinate (HEG) was investigated for comparison. A suite of biomechanical and biochemical assays including FTIR, drying stress, and cellular cohesion were used. …”
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4628por Guo, Fei, Li, Bingzhang, Ding, Rui, Li, Dongsheng, Jiang, Xiaobin, He, Gaohong, Xiao, Wu“…Simultaneously, the close connection of the UiO-66 layer on the external surface of HNTs created relatively continuous pathways for gas permeation. A suite of microscopy, diffraction, and thermal techniques was used to characterize the morphology and structure of UiO-66@HNT and the membranes. …”
Publicado 2021
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4629“…CMB-F214, revealed the known chrysosporazines A–D (11–14) in addition to a suite of very minor aza analogues 1–6. A microbioreactor (MATRIX) cultivation profiling analysis failed to deliver cultivation conditions that significantly improved the yields of 1–6; however, it did reveal that M2 agar cultivation produced the new natural product 15. …”
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4630por Akdel, Mehmet, van de Geest, Henri, Schijlen, Elio, van Rijswijck, Irma M. H., Smid, Eddy J., Sanchez-Perez, Gabino, de Ridder, Dick“…These tools lay the foundation for a suite of open-source methods to process and analyze high-throughput optical mapping data. …”
Publicado 2021
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4631por Jacobsen, Deidra J.“…Plant‐herbivore coevolutionary interactions have led to a range of plant defenses that minimize insect damage and a suite of counter adaptations that allow herbivores to feed on defended plants. …”
Publicado 2021
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4632“…Here, we present a Python package called paraSBOLv that enables access to the full suite of SBOLv glyphs through the use of machine-readable parametric glyph definitions. …”
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4633por Bruce, Spencer A., Huang, Yen-Hua, Kamath, Pauline L., van Heerden, Henriette, Turner, Wendy C.“…In this study, we investigate the effects of antimicrobial resistance, phage diversity, geography and isolation source in shaping population genomic structure. We also identify a suite of candidate genes potentially under selection, driving patterns of diversity across 356 globally extant B. anthracis genomes. …”
Publicado 2021
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4634por Weber, Annika M., Baxter, Bridget A., McClung, Anna, Lamb, Molly M., Becker-Dreps, Sylvia, Vilchez, Samuel, Koita, Ousmane, Wieringa, Frank, Ryan, Elizabeth P.“…Here, we assessed how agronomic practices and postharvest fermentation techniques influence As concentrations in rice bran, and calculated health risks from consumption. A global suite of 53 rice brans were tested for total As and speciation. …”
Publicado 2021
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4635“…We derive inference procedures for the proposed estimators under mild conditions and demonstrate their finite sample performance through a suite of simulation experiments and an illustrative application to data from a study of bipolar depression.…”
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4636“…Finally, we find that the inferred thermodynamics of triplet sensitization from these ultra-small PbS quantum dots are surprisingly favourable—completing an advantageous suite of properties for upconversion photochemistry—and do not vary significantly across the ensemble, which indicates minimal effects from nanocrystal heterogeneity. …”
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4637por zur Lage, Petra, Xi, Zhiyan, Lennon, Jennifer, Hunter, Iain, Chan, Wai Kit, Bolado Carrancio, Alfonso, von Kriegsheim, Alex, Jarman, Andrew P.“…Ciliary motility is powered by a suite of highly conserved axoneme-specific dynein motor complexes. …”
Publicado 2021
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4638por Cortes-Figueiredo, Filipe, Carvalho, Filipa S., Fonseca, Ana Catarina, Paul, Friedemann, Ferro, José M., Schönherr, Sebastian, Weissensteiner, Hansi, Morais, Vanessa A.“…However, its bioinformatic processing occurs in the enterprise Ion Torrent Suite™ Software (TSS), yielding BAM files aligned to an unorthodox version of the revised Cambridge Reference Sequence (rCRS), with a heteroplasmy threshold level of 10%. …”
Publicado 2021
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4639“…The aim of this feasibility study was to establish whether a suite of purposively constructed animated films and digital resources could positively impact on parent and child outcomes in the early years. …”
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4640por Morotti, Stefano, Liu, Caroline, Hegyi, Bence, Ni, Haibo, Fogli Iseppe, Alex, Wang, Lianguo, Pritoni, Marco, Ripplinger, Crystal M., Bers, Donald M., Edwards, Andrew G., Grandi, Eleonora“…We demonstrate that this approach is well suited to predicting the effects of perturbations across different species or experimental conditions and suggest its integration into mechanistic studies and drug development pipelines.…”
Publicado 2021
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