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  1. 5001
    “…We propose a new computational approach that combines traditional structure-based modeling using the Rosetta software suite with machine learning and integer linear programming to overcome limitations in the Rosetta sampling methods. …”
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    Integrating linear optimization with structural modeling to increase HIV neutralization breadth
  2. 5002
    “…Here we investigate the sources of variation in faecal strongyle eggs counts, and its association with body weight and a suite of haematological measures, in a cohort of indigenous zebu calves in Western Kenya, using relatedness matrices reconstructed from single nucleotide polymorphism (SNP) genotypes. …”
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    Variation and covariation in strongyle infection in East African shorthorn zebu calves
  3. 5003
    “…The current implementation of the model replaces the generic protein PBPK model available in PK-Sim since version 4.2 and becomes part of the Open Systems Pharmacology Suite. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s10928-017-9559-4) contains supplementary material, which is available to authorized users.…”
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    A generic whole body physiologically based pharmacokinetic model for therapeutic proteins in PK-Sim
  4. 5004
    “…We show that SD sequence utilization covaries with a suite of genomic features that are important for efficient translation initiation and elongation. …”
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    Diversity of Translation Initiation Mechanisms across Bacterial Species Is Driven by Environmental Conditions and Growth Demands
  5. 5005
    “…However, there is a shortage of quantitative methods to measure and characterize the different dynamic regimes observed. Herein, a suite of open-source computational methods and original algorithms were integrated into an automated analysis pipeline that we employed to characterize specific oscillatory signatures in pollen tubes of Arabidopsis thaliana (Col-0). …”
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    Oscillatory signatures underlie growth regimes in Arabidopsis pollen tubes: computational methods to estimate tip location, periodicity, and synchronization in growing cells
  6. 5006
    “…Bivalves have evolved a range of complex shell forming mechanisms that are reflected by their incredible diversity in shell mineralogy and microstructures. A suite of proteins exported to the shell matrix space plays a significant role in controlling these features, in addition to underpinning some of the physical properties of the shell itself. …”
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    Insights from the Shell Proteome: Biomineralization to Adaptation
  7. 5007
    “…The contribution of plants to changes in future heat extremes will depend on the responses of vegetation growth and physiology to the direct and indirect effects of elevated CO(2). Here we use a suite of earth system models to disentangle the radiative versus vegetation effects of elevated CO(2) on heat wave characteristics. …”
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    Amplification of heat extremes by plant CO(2) physiological forcing
  8. 5008
    “…In particular, neurological networks are potentially vulnerable to the epigenetic dysregulation of Alu elements operating across the suite of nuclear-encoded mitochondrial genes that are critical for both mitochondrial and CNS function. …”
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    Warning SINEs: Alu elements, evolution of the human brain, and the spectrum of neurological disease
  9. 5009
    “…NPAS was combined with subcellular protein localization data, facilitating quantitative estimations of organelle abundance during routine experimental procedures. A suite of targeted proteomics markers for subcellular compartment markers was developed, enabling independent verification of in silico estimates for relative organelle abundance. …”
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    Multiple marker abundance profiling: combining selected reaction monitoring and data‐dependent acquisition for rapid estimation of organelle abundance in subcellular samples
  10. 5010
    “…Colobops noviportensis reveals extraordinary disparity of the feeding apparatus in small-bodied early Mesozoic diapsids, and a suite of morphologies, functionally related to a powerful bite, unknown in any small-bodied diapsid.…”
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    A tiny Triassic saurian from Connecticut and the early evolution of the diapsid feeding apparatus
  11. 5011
    “…To function properly, organisms must adjust their physiology, behavior and metabolism in response to a suite of varying environmental conditions. One of the central regulators of these changes is organisms’ internal circadian clock, and recent evidence has suggested that the clock genes are also important in the regulation of seasonal adjustments. …”
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    Photosensitive Alternative Splicing of the Circadian Clock Gene timeless Is Population Specific in a Cold-Adapted Fly, Drosophila montana
  12. 5012
    “…The final text of the Trans Pacific Partnership Agreement (TPP), agreed between the 12 negotiating countries in 2016, included a suite of intellectual property provisions intended to expand and extend pharmaceutical company exclusivities on medicines. …”
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    The Trans Pacific Partnership Agreement, intellectual property and medicines: Differential outcomes for developed and developing countries
  13. 5013
    “…In this study, the workflow and performance characteristics of a fully automated ANA IIF system (Sprinter XL, EUROPattern Suite, IFA 40: HEp-20-10 cells) were compared to a manual approach using visual microscopy with a filter device for single-well titration and to technologist reading. …”
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    Automated Processing and Evaluation of Anti-Nuclear Antibody Indirect Immunofluorescence Testing
  14. 5014
    “…[Image: see text] The application of surface-enhanced Raman spectroscopy (SERS) for everyday quantitative analysis is hindered by the point-to-point variability of SERS substrates that arises due to the heterogeneous distribution of localized electromagnetic fields across a suite of plasmonic nanostructures. Herein, we adopt surface-enhanced elastic scattering as a SERS internal standard. …”
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    Improved Quantitative SERS Enabled by Surface Plasmon Enhanced Elastic Light Scattering
  15. 5015
    “…The resultant energy-rich methane can be oxidized via a suite of electron acceptors. Recently, ‘Candidatus Methanoperedens nitroreducens’ ANME-2d archaea and ‘Candidatus Methylomirabilis oxyfera’ bacteria were enriched on nitrate and nitrite under anoxic conditions with methane as an electron donor. …”
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    The hunt for the most-wanted chemolithoautotrophic spookmicrobes
  16. 5016
    por Liu, Chunyan, Zou, Gen, Yan, Xing, Zhou, Xuguo
    Publicado 2018
    “…Termite gut microbiome is a rich reservoir for glycoside hydrolases, a suite of enzymes critical for the degradation of lignocellulosic biomass. …”
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    Screening of multimeric β-xylosidases from the gut microbiome of a higher termite, Globitermes brachycerastes
  17. 5017
    “…The listed events that have many missing data gaps were used to reference and validate results obtained from other sources in this study. A suite of ten climate change extreme precipitation indices derived from daily precipitation data (Grootfontein rainfall station), were calculated and analysed. …”
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    Identifying hydro-meteorological events from precipitation extremes indices and other sources over northern Namibia, Cuvelai Basin
  18. 5018
    “…Cell abundances ranged from 0 to 1.6 × 10(4) cells ml(−1), with algal biomass demonstrated to increase in surface ice with time since snow line retreat (R(2) = 0.73, P < 0.05). A suite of light harvesting and photo-protective pigments were quantified across transects (chlorophylls, carotenoids and phenols) and shown to increase in concert with algal biomass. …”
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    Ice algal bloom development on the surface of the Greenland Ice Sheet
  19. 5019
    “…The results indicated that combining available soil pH and STC content data with VisNIR spectra dramatically improved prediction accuracy of the Cubist models. Using the full suite of predictor variables, Cubist models trained on the calibration dataset (75%) could predict the validation dataset (25%) for SOC content with a Lin’s concordance correlation coefficient (LCCC) of 0.94, and an LCCC of 0.83 for SIC content. …”
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    Combining ancillary soil data with VisNIR spectra to improve predictions of organic and inorganic carbon content of soils
  20. 5020
    “…The patient was monitored with invasive blood pressure (BP), electrocardiogram (ECG), heart rate, SpO(2), and arterial gas analysis as from entry into the operation suite. We performed total intravenous anesthesia with nitroglycerin inhalation. …”
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    Intravenous anesthesia with nitroglycerin inhalation for surgical abortion in a patient with severe congenital heart disease and low oxygen saturation: A case report
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