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6241“…These structural patterns are impacted by a suite of variables, including species traits, species abundances, their spatial configuration, and their phylogenetic history. …”
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6242“…Here, we interrogated a rich data set of neuroectodermal enhancers in Drosophila, representing cis- and trans- sources of expression variation, with a suite of biophysical and machine learning models. …”
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6243por Wofford, Haley A., Myers-Dean, Josh, Vogel, Brandon A., Alamo, Kevin Alexander Estrada, Longshore-Neate, Frederick A., Jagodzinski, Filip, Amacher, Jeanine F.“…Here, we developed a computational software suite, Domain Analysis and Motif Matcher (DAMM), that analyzes peptide-binding cleft sequence identity as compared with human PDZ domains and that can be used in combination with literature searches of known human PDZ-interacting sequences to predict target specificity in choanoflagellate PDZ domains. …”
Publicado 2021
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6244por Salas-Leiva, Dayana E., Tromer, Eelco C., Curtis, Bruce A., Jerlström-Hultqvist, Jon, Kolisko, Martin, Yi, Zhenzhen, Salas-Leiva, Joan S., Gallot-Lavallée, Lucie, Williams, Shelby K., Kops, Geert J. P. L., Archibald, John M., Simpson, Alastair G. B., Roger, Andrew J.“…Carpediemonas species are thus the first known eukaryotes that appear to lack this suite of conserved complexes, suggesting that they likely rely on yet-to-be-discovered or alternative mechanisms to carry out these fundamental processes.…”
Publicado 2021
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6245por Gao, Mingxuan, Yang, Wenxian, Li, Chenxin, Chang, Yuqing, Liu, Yachen, He, Qingzu, Zhong, Chuan-Qi, Shuai, Jianwei, Yu, Rongshan, Han, Jiahuai“…We developed DreamDIA(XMBD) (denoted as DreamDIA), a software suite based on a deep representation model for data-independent acquisition (DIA) data analysis. …”
Publicado 2021
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6246por Xu, Yong, Peng, Wenpan, Han, Di, Wang, Zhichao, Feng, Fanchao, Zhou, Xianmei, Wu, Qi“…The PharmMapper, SwissTargetPrediction, SEA, and TCMID databases were used to screen for the active ingredients and therapeutic targets of Chansu injection, while the OMIM and GeneCards Suite databases were used to search for COVID-19-related targets. …”
Publicado 2021
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6247por Velázquez, Elena, Al-Ramahi, Yamal, Tellechea-Luzardo, Jonathan, Krasnogor, Natalio, de Lorenzo, Víctor“…These results show the value of the targetron approach for the unrestricted delivery of small DNA fragments to precise locations in the genomes of Gram-negative bacteria, which will be useful for a suite of genome editing endeavors.…”
Publicado 2021
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6248por Saih, Asmae, Bouqdayr, Meryem, Baba, Hanâ, Hamdi, Salsabil, Moussamih, Samya, Bennani, Houda, Saile, Rachid, Wakrim, Lahcen, Kettani, Anass“…In the current study, we used different available tools like SIFT, PolyPhen2.0, PROVEAN, SNAP2, PMut, MutPred2, I-Mutant Suite, MUpro, iStable, ConSurf, ModPred, SwissModel, PROCHECK, Verify3D, and TM-align to identify the most deleterious variants and to explore possible effects on the TMPRSS2 stability, structure, and function. …”
Publicado 2021
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6249por Singer, Stacy D., Subedi, Udaya, Lehmann, Madeline, Burton Hughes, Kimberley, Feyissa, Biruk A., Hannoufa, Abdelali, Shan, Bin, Chen, Guanqun, Kader, Kazi, Ortega Polo, Rodrigo, Schwinghamer, Timothy, Kaur Dhariwal, Gaganpreet, Acharya, Surya“…These findings imply that different falcata accessions/genotypes may employ distinct drought response mechanisms, and the study provides a suite of candidate genes to facilitate the breeding of alfalfa with enhanced drought resilience in the future.…”
Publicado 2021
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6250“…In this study, we use the model zooplankton Daphnia magna and its relatively simple cohort of bacterial taxa to disentangle the roles of distinct taxa in host life history metrics, using a suite of antibiotics to selectively reduce the abundance of functionally important taxa. …”
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6251“…Univariable logistical regression models were used to evaluate potential risk factors for development of surgical site infections including signalment, tumor type, antibiotic protocol, time under anesthesia, location of surgical procedure (dental suite vs. sterile operating room), specific comorbidities, and surgical margins obtained. …”
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6252por Picton, David M, Luyten, Yvette A, Morgan, Richard D, Nelson, Andrew, Smith, Darren L, Dryden, David T F, Hinton, Jay C D, Blower, Tim R“…Here, we have functionally characterised a defence island from a multidrug resistant plasmid of the emerging pathogen Escherichia fergusonii. Using a suite of thirty environmentally-isolated coliphages, we demonstrate multi-layered and robust phage protection provided by a plasmid-encoded defence island that expresses both a type I BREX system and the novel GmrSD-family type IV DNA modification-dependent restriction enzyme, BrxU. …”
Publicado 2021
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6253por Ding, Hao, Dixon Wilkins, Malin C., Mottram, Lucy M., Blackburn, Lewis R., Grolimund, Daniel, Tappero, Ryan, Nicholas, Sarah L., Sun, Shikuan, Corkhill, Claire L., Hyatt, Neil C.“…In the present work, we elaborate and evaluate approaches to the construction of 2D speciation maps, in an effort to maximize sensitivity to the U oxidation state at the U L (3)-edge, applied to a suite of synthetic Chernobyl lava specimens. Our analysis shows that calibration of speciation maps can be improved by determination of the normalized X-ray absorption at excitation energies selected to maximize oxidation state contrast. …”
Publicado 2021
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6254por Mayer, Marisa H., Parenteau, Mary N., Kempher, Megan L., Madigan, Michael T., Jahnke, Linda L., Welander, Paula V.“…Both Rhodopila globiformis, a phototrophic purple nonsulfur bacterium isolated from an acidic warm spring in Yellowstone, and a newly isolated Rhodopila species from a geochemically similar spring in Lassen Volcanic National Park (USA), synthesized 3-methylhopanoids and a suite of related hopanoids and contained the genes encoding the necessary biosynthetic enzymes. …”
Publicado 2021
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6255por Alsultan, Abdullah, Dasuqi, Shereen A., Aljamaan, Fadi, Omran, Rasha A., Syed, Saeed Ali, AlJaloud, Turki, AlAhmadi, Abdullah, Alqahtani, Saeed, Hamad, Mohammed A.“…Pharmacokinetic analysis was performed using Monolix Suite 2020R1 (Lixoft, France). RESULTS: Trough concentrations were highly variable and ranged from <0.5 µg/mL to 39 µg/mL, with a mean ± SD trough concentration of 8.5 ± 8 µg/mL. …”
Publicado 2021
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6256por Phan, Huy P., Ngu, Bing H., Chen, Si-Chi, Lin, Ruey-Yih, Wang, Hui-Wen, Shih, Jen-Hwa, Shi, Sheng-Ying“…Six hundred and twenty-seven university students (N = 438 women, 189 men) responded to a suite of self-report questionnaires. Structural equation modelling (SEM) techniques were used to test a conceptual model, where we focused on the antecedent (i.e., the direct impact of self-efficacy on a perceived feeling of energy) and consequence of a perceived feeling energy (i.e., the impact of a perceived feeling of energy on personal resolve, and the sustaining of optimal best). …”
Publicado 2021
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6257por Bartolomei, Mirco, Olivieri, Lorenzo, Bettanini, Carlo, Cavazzani, Stefano, Fiorentin, Pietro“…In the framework of the MINLU project, two SQM-LE units were integrated in an autonomous sensor suite realized and tested at University of Padova for monitoring light pollution from drones or sounding balloons. …”
Publicado 2021
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6258por Remple, Kristina L., Silbiger, Nyssa J., Quinlan, Zachary A., Fox, Michael D., Kelly, Linda Wegley, Donahue, Megan J., Nelson, Craig E.“…Our findings demonstrate how biofilm successional trajectories diverge from temporal dynamics of the bacterioplankton and how biofilms are structured by the surrounding benthic organisms and nutrient enrichment. We identify a suite of biofilm-associated bacteria linked with the orthogonal influences of corals, algae and nutrients and distinct from the overlying water. …”
Publicado 2021
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6259por Noh, Thomas, Juvekar, Parikshit, Huang, Raymond, Lee, Gunnar, Ogasawara, Christian T., Golby, Alexandra J.“…METHODS: We retrospectively reviewed all LITT cases performed in our intraoperative MRI suite for tumors between 2017 and 2020. We identified a total of 17 LITT cases. …”
Publicado 2021
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6260por Chalichem, Nehru Sai Suresh, Jupudi, Srikanth, Yasam, Venkata Ramesh, Basavan, Duraiswamy“…MATERIAL AND METHODS: The phytoconstituent was subjected for various in silico studies (using Schrödinger Suite) like, Docking analysis, molecular mechanics combined with generalized Born model and solvent accessibility method (MMGBSA) and Induced fit docking (IFD) after validating the protein using Ramachandran plot. …”
Publicado 2021
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