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  1. 20881
    “…The vaccine efficacy of the formulations was analyzed by mouse serum antigen-specific antibody titer, toxin neutralization assay, and survival analysis of mouse groups challenged with a lethal dose of B. anthracis virulent spores. …”
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    Recombinant full-length Bacillus Anthracis protective antigen and its 63 kDa form elicits protective response in formulation with addavax
  2. 20882
    “…Almost all vaccinated individuals (15 670/15 681) acquired binding antibodies with higher titers among booster dose recipients. CONCLUSIONS: Before Omicron, the cumulative burden was >10 times lower in Japan (2.2%) compared with the US (33%), the UK (25%), or global estimates (45%), but most developed antibodies owing to vaccination.…”
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    National seroepidemiological study of COVID‐19 after the initial rollout of vaccines: Before and at the peak of the Omicron‐dominant period in Japan
  3. 20883
    “…The compounds TAK 901, JNJ 7706621, and PF 03814735 decreased HSV-1 titers by 4,500-, 13,200-, and 8,400-fold, respectively, when present in a low micromolar range. …”
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    Inhibitors of One or More Cellular Aurora Kinases Impair the Replication of Herpes Simplex Virus 1 and Other DNA and RNA Viruses with Diverse Genomes and Life Cycles
  4. 20884
    “…In vivo monoinfection with the ΔdegP strain revealed a lower symbiont titer in the symbiotic organ than that of the wild-type strain, indicating that the ΔdegP strain failed to persist in the host. …”
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    Proteolytic Activity of DegP Is Required for the Burkholderia Symbiont To Persist in Its Host Bean Bug
  5. 20885
    “…Assay precision measuring intra-assay variability produced acceptable results for high (50% PRNT [PRNT(50)], 1:≥640), mid (PRNT(50), 1:160), and low (PRNT(50), 1:40) antibody titer concentration ranges based on the PRNT(50), with coefficients of variation (CVs) of 14.21%, 12.47%, and 13.28%, respectively. …”
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    Validation and Establishment of the SARS-CoV-2 Lentivirus Surrogate Neutralization Assay as a Prescreening Tool for the Plaque Reduction Neutralization Test
  6. 20886
    “…Such tests are also susceptible to false-positive results due to trace contamination from high viral titer samples. Host immune response markers provide an orthogonal indication of infection that can mitigate these concerns when combined with direct viral detection. …”
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    A 2-Gene Host Signature for Improved Accuracy of COVID-19 Diagnosis Agnostic to Viral Variants
  7. 20887
    “…In conclusion, a significantly diminished and delayed immune pattern was observed in ESRD patients compared to healthy population, with a peak in antibody titers occurring 3–5 weeks after the second dose. …”
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    Cellular and Humoral Responses in Dialysis Patients after Vaccination with the BNT162b2 or mRNA-1273 Vaccines
  8. 20888
    “…In vivo, our results show reduced disease and viral replication at late times in the hamster lung, but an earlier titer deficit for the NSP16 mutant (dNSP16) in the upper airway. …”
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    SARS-CoV-2 Uses Nonstructural Protein 16 To Evade Restriction by IFIT1 and IFIT3
  9. 20889
    “…The presence of autoimmunity was considered if IgG level >1.1 × ULN (1826 mg/dL), or high titer (>1:80) of ANA, or SMA. Results: In total, 441 patients were enrolled, and the median age was 63.3 years (IQR, 61.0–66.0); 122 (27.7%), 195 (44.2%), or 124 (28.1%) were classified as having minor, moderate, or severe hepatic inflammation, respectively; and 188 (42.6%), 210 (47.6%) or 43 (9.8%) patients presented minor, significant fibrosis or cirrhosis, respectively. …”
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    Autoimmunity associates with severity of illness in elderly patients with drug-induced liver injury
  10. 20890
    “…The secondary objectives included demonstration of non-inferiority of YF and dengue geometric mean titers (GMTs) (UB95%CI for GMT ratio <2.0), and safety. …”
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    Immunogenicity and safety of concomitant and sequential administration of yellow fever YF-17D vaccine and tetravalent dengue vaccine candidate TAK-003: A phase 3 randomized, controlled study
  11. 20891
    “…CONCLUSION: CAM cases differed from the controls in terms of higher titers of proinflammatory cytokines, reduced frequency of total and cytotoxic CD56 + CD16 + NK cell. …”
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    Higher proinflammatory responses possibly contributing to suppressed cytotoxicity in patients with COVID-19 associated mucormycosis
  12. 20892
    “…Viral replication and infectivity were assessed by detection of viral RNA copies and viral titers; the degree of inflammation in mice was tested by whole blood cell count, ELISA and RT-qPCR assays; the pathogenicity of SARS-CoV-2/BMA8 in mice was measured by Histopathology and Immunohistochemistry; and the immune level of mice was evaluated by flow cytometry to detect the number of CD8(+) T cells. …”
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    MHC class I links with severe pathogenicity in C57BL/6N mice infected with SARS-CoV-2/BMA8
  13. 20893
    “…RESULTS/ANTICIPATED RESULTS: MIS-C patients had higher IgG antibody titers against SARS-CoV-2 compared to children with symptomatic or asymptomatic COVID. …”
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    355 Unraveling and targeting the innate immune response in Multisystem Inflammatory Syndrome in Children (MIS-C)
  14. 20894
    “…In addition, patients with persistent CSF NMDAR-Abs at 12 months had higher titers of CSF NMDAR-Abs at diagnosis. DISCUSSION: In this study, patients with persistent CSF NMDAR-Abs at 12 months were more likely to have subsequent relapses and a poor long-term outcome. …”
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    Prognostic Value of Persistent CSF Antibodies at 12 Months in Anti-NMDAR Encephalitis
  15. 20895
    “…BACKGROUND: The ABC method, which combines the pepsinogen method and anti-Helicobacter pylori antibody titers, has been used for risk screening for gastric cancer in Japan. …”
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    Diagnostic performance of the normal range of gastrin calculated using strict criteria based on a combination of serum markers and pathological evaluation for detecting gastritis: a retrospective study
  16. 20896
    “…Pediatric patients diagnosed with COVID-19 by positive molecular assay using nasopharyngeal swab will be tested for anti–SARS-CoV-2 antibodies using the Roche Elecsys Anti-SARS-CoV-2 S assay at the time of diagnosis and at 2 weeks and 1, 3, and 6 months following infection. Antibody titer data will be reported as means and SDs. The respondents’ signs and symptoms will be observed up to 6 months after the onset of infection, including the vaccination event, reinfection, rehospitalization, and mortality. …”
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    The Kinetics of Anti–SARS-CoV-2 Antibodies in Pediatric Patients and the Characterization of Post–COVID-19 Condition at 6 Months After Infection: Protocol for a Longitudinal Observational Study
  17. 20897
    “…Multivariate analysis identified baseline MFI >20,000 as an independent risk factor for survival and an increase in titers after infusion as an independent risk factor for GF. …”
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    Results of haploidentical transplant in patients with donor-specific antibodies: a survey on behalf of the Spanish Group of Hematopoietic Transplant and Cell Therapy
  18. 20898
    por Chen, Nicholas F. G., Chaguza, Chrispin, Gagne, Luc, Doucette, Matthew, Smole, Sandra, Buzby, Erika, Hall, Joshua, Ash, Stephanie, Harrington, Rachel, Cofsky, Seana, Clancy, Selina, Kapsak, Curtis J., Sevinsky, Joel, Libuit, Kevin, Park, Daniel J., Hemarajata, Peera, Garrigues, Jacob M., Green, Nicole M., Sierra-Patev, Sean, Carpenter-Azevedo, Kristin, Huard, Richard C., Pearson, Claire, Incekara, Kutluhan, Nishimura, Christina, Huang, Jian Ping, Gagnon, Emily, Reever, Ethan, Razeq, Jafar, Muyombwe, Anthony, Borges, Vítor, Ferreira, Rita, Sobral, Daniel, Duarte, Silvia, Santos, Daniela, Vieira, Luís, Gomes, João Paulo, Aquino, Carly, Savino, Isabella M., Felton, Karinda, Bajwa, Moneeb, Hayward, Nyjil, Miller, Holly, Naumann, Allison, Allman, Ria, Greer, Neel, Fall, Amary, Mostafa, Heba H., McHugh, Martin P., Maloney, Daniel M., Dewar, Rebecca, Kenicer, Juliet, Parker, Abby, Mathers, Katharine, Wild, Jonathan, Cotton, Seb, Templeton, Kate E., Churchwell, George, Lee, Philip A., Pedrosa, Maria, McGruder, Brenna, Schmedes, Sarah, Plumb, Matthew R., Wang, Xiong, Barcellos, Regina Bones, Godinho, Fernanda M. S., Salvato, Richard Steiner, Ceniseros, Aimee, Breban, Mallery I., Grubaugh, Nathan D., Gallagher, Glen R., Vogels, Chantal B. F.
    Publicado 2023
    “…We found notably higher genome coverage across the virus genome, with minimal amplicon drop-outs, in using the amplicon-based sequencing approach, particularly in higher PCR cycle threshold (Ct) (lower DNA titer) samples. Further testing demonstrated that Ct value correlated with the number of sequencing reads and influenced the percent genome coverage. …”
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    Development of an amplicon-based sequencing approach in response to the global emergence of mpox
  19. 20899
    “…Subsequently, the immune responses induced by this mutant in mice and cats were detected, including antibody titers, cytokine levels, and subsets of T lymphocytes. …”
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    A live attenuated RHΔompdcΔuprt mutant of Toxoplasma gondii induces strong protective immunity against toxoplasmosis in mice and cats
  20. 20900
    “…Furthermore, we investigated the dynamics of the anti-acetylcholine receptor-antibody titers and concurrent immunosuppressive therapies, as well as the therapeutic outcomes in dependence of clinical classifications. …”
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    The impact of thymectomy in subgroups of Myasthenia gravis patients: a single center longitudinal observation
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