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21001por Zhao, Jun, Zhang, Rubo, Zhu, Ling, Deng, Huidan, Li, Fengqing, Xu, Lei, Huan, Jianbo, Sun, Xiangang, Xu, Zhiwen“…Evaluation of antibody responses and neutralizing antibody titers is the most effective method for vaccine evaluation. …”
Publicado 2021
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21002por Okoroafor, Obianuju Nkiruka, Ogunniran, Temitope Mofoluso, Ikenna-Ezeh, Nkechi Harriet, Udeani, Ikechukwu John, Omeke, Jacinta Ngozi, Ezema, Wilfred Sunday, Anene, Boniface“…Increases in the mean antibody titers were observed in the NDV-challenged group when compared with the UCCs from days 3 to 21 pi. …”
Publicado 2021
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21003por Calzas, Cynthia, Mao, Molida, Turpaud, Mathilde, Viboud, Quentin, Mettier, Joelle, Figueroa, Thomas, Bessière, Pierre, Mangin, Antoine, Sedano, Laura, Hervé, Pierre-Louis, Volmer, Romain, Ducatez, Mariette F., Bourgault, Steve, Archambault, Denis, Le Goffic, Ronan, Chevalier, Christophe“…Mice vaccinated with chimeric nanorings bearing IAV epitopes in fusion with P97c presented modest LAH- or M2e-specific IgG titers in serum and were unable to generate a mucosal humoral response. …”
Publicado 2021
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21004por August, Allison, Attarwala, Husain Z., Himansu, Sunny, Kalidindi, Shiva, Lu, Sophia, Pajon, Rolando, Han, Shu, Lecerf, Jean-Michel, Tomassini, Joanne E., Hard, Marjie, Ptaszek, Leon M., Crowe, James E., Zaks, Tal“…At 12, 24 and 48 h after single infusions, dose-dependent levels of CHKV-24 IgG with neutralizing activity were observed at titers predicted to be therapeutically relevant concentrations (≥1 µg ml(−1)) across doses that persisted for ≥16 weeks at 0.3 and 0.6 mg kg(−1) (mean t(1/2) approximately 69 d). …”
Publicado 2021
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21005por Schmelter, Franziska, Föh, Bandik, Mallagaray, Alvaro, Rahmöller, Johann, Ehlers, Marc, Lehrian, Selina, von Kopylow, Vera, Künsting, Inga, Lixenfeld, Anne Sophie, Martin, Emily, Ragab, Mohab, Meyer-Saraei, Roza, Kreutzmann, Fabian, Eitel, Ingo, Taube, Stefan, Käding, Nadja, Jantzen, Eckard, Graf, Tobias, Sina, Christian, Günther, Ulrich L.“…In contrast, anti-SARS-CoV-2 antibody-positive individuals without acute COVID-19 did not show a significantly perturbed metabolic profile compared with age- and sex-matched healthy controls, but SARS-CoV-2 antibody-titers correlated significantly with metabolic parameters, including levels of glycine, ApoA2, and small-sized low- and high-density lipoprotein subfractions. …”
Publicado 2021
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21006por Gualano, Bruno, Lemes, Italo R., Silva, Rafael P., Pinto, Ana J., Mazzolani, Bruna C., Smaira, Fabiana I., Sieczkowska, Sofia M., Aikawa, Nadia E., Pasoto, Sandra G., Medeiros-Ribeiro, Ana C., Saad, Carla G.S., Yuki, Emily F.N., Silva, Clovis A., Swinton, Paul, Hallal, Pedro C., Roschel, Hamilton, Bonfa, Eloisa“…Immunogenicity was assessed after vaccination by measuring seroconversion rates of total anti-SARS-CoV-2 S1/S2 IgG (SC), geometric mean titers of anti-S1/S2 IgG (GMT), factor-increase in GMT (FI-GMT), frequency of neutralizing antibody (NAb), and median neutralizing activity. …”
Publicado 2022
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21007“…Piglets immunized with the PRV GDFS-delgI/gE/US9/US2 vaccine did not produce PRV gE-specific antibodies but could generate PRV gB-specific antibodies and high neutralizing titers against the PRV GDFS strain (variant PRV strain) or PRV Ea strain (older PRV strain). …”
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21008por Zhang, Pingping, Li, Baisheng, Wang, Yao, Min, Wei, Wang, Xiaohui, Zhou, Yugui, Li, Zhencui, Zhao, Yong, Zhang, Huan, Jiang, Min, Zheng, Huanying, Yang, Chao, Zhang, Wei, Zuo, Le, Gao, Qi, Yang, Zhengrong, Li, Yanzhao, Feng, Tiejian, Lin, Changqing, Hu, Qinghua, Song, Tie, Yang, Ruifu“…We evaluated RBD-specific antibodies for 528 seral samples from 213 recovered and 99 RP COVID-19 patients, along with 35 seral samples from inactivated SARS-CoV-2 vaccinees, and we discovered that the total RBD-specific antibody level indicated by T/C ratios of UPT-POCT was significantly related to the NAb titers in both COVID-19 patients (r = 0.9404, n = 527; ρ = 0.6836, n = 528) and the vaccinees (r = 0.9063, ρ = 0.7642, n = 35), and it was highly relevant to the protection rate against RP (r = 0.9886, n = 312). …”
Publicado 2022
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21009por Scoles, Glen A., Hussein, Hala E., Olds, Cassandra L., Mason, Kathleen L., Davis, Sara K.“…The vaccinated calf with the highest total IgG titer was not the most effective at controlling ticks; ratios of IgG isotypes 1 and 2 differed greatly among the three vaccinated cattle; the calf with the highest IgG1/IgG2 ratio had the fewest ticks. …”
Publicado 2022
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21010por Chang, Jer-Hwa, Chiou, Jeng-Fong, Hung, Ching-Sheng, Liu, Ming-Che, Chang, Hui-Wen, Hong, Shiao-Ya, Wang, Cheng-Yi, Lin, Yi-Ling, Hsieh, Yi-Chen, Chung, Chi-Li, Su, Ying-Shih, Hsiao, Shu-Tai Shen, Liu, Doresses, Liang, Jian-Jong, Liao, Chun-Che, Chang, Chih-Shin, Lai, Kevin Shu-Leung, Chuang, Han-Chuan, Chien, Ko-Ling, Wu, Wei-Ciao, Lee, Yuan-Chii G., Lin, Sey-En, Shen, Yung-Kang, Hsu, Chiung-Fang, Wang, Jude Chu-Chun, Hsiao, Shih-Hsin“…Their specific SARS-CoV-2 antibodies, neutralizing antibody titers (NT50), platelet counts, and D-dimer levels were analyzed before and after vaccination. …”
Publicado 2022
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21011por Serré, Jef, Tanjeko, Ajime Tom, Mathyssen, Carolien, Heigl, Tobias, Sacreas, Annelore, Cook, Dana Paulina, Verbeken, Erik, Maes, Karen, Verhaegen, Jan, Pilette, Charles, Vanoirbeek, Jeroen, Gysemans, Conny, Mathieu, Chantal, Vanaudenaerde, Bart, Janssens, Wim, Gayan-Ramirez, Ghislaine“…In addition, VDD led to an increase in total lung capacity (TLC), lung compliance (Cchord), MMP12/TIMP1 ratio with a rise in serum Ig titers and anti-dsDNA Ig’s. Interestingly, in non-infected animals, VDD exacerbated the CS-induced anti-NTHi Ig’s, anti-dsDNA Ig’s and inflammatory cells within the lung. …”
Publicado 2022
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21012por Rodrigues, Esthefany S., Santos, Gilbert Q., da Silva, Marlon Vicente, Barros, Juliana H. S., Bernardo, Aline R., Diniz, Rafaela L., Rubim, Nara M., Roque, André L. R., Jansen, Ana Maria, Silva, Edimilson D., Xavier, Samanta C. C.“…We observed that the intensity pattern of the bands was directly proportional to the serological titer observed in IFAT. The sensitivity was 94%, the specificity was 91% according to the ROC curve, and the defined cutoff was an optical density of 4.8. …”
Publicado 2022
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21013por Speich, Benjamin, Chammartin, Frédérique, Abela, Irene A, Amico, Patrizia, Stoeckle, Marcel P, Eichenberger, Anna L, Hasse, Barbara, Braun, Dominique L, Schuurmans, Macé M, Müller, Thomas F, Tamm, Michael, Audigé, Annette, Mueller, Nicolas J, Rauch, Andri, Günthard, Huldrych F, Koller, Michael T, Trkola, Alexandra, Briel, Matthias, Kusejko, Katharina, Bucher, Heiner C“…Based on the Elecsys test, all PLWH had an antibody response (100.0%; 341/341), whereas for SOTR, only 60.6% (95% CI: 49.2–71.9; 43/71) had titers above the cutoff level. CONCLUSIONS: In immunocompromised patients, the antibody response of mRNA-1273 was noninferior to BNT162b2. …”
Publicado 2022
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21014por Bilgin, Huseyin, Marku, Marisa, Yilmaz, Sultan Seval, Karahasan Yagci, Aysegul, Sili, Uluhan, Can, Baris, Can Sarinoglu, Rabia, Mulazimoglu Durmusoglu, Lutfiye, Haklar, Goncagul, Sirikci, Onder, Eksioglu Demiralp, Emel“…RESULTS: The Anti-S antibodies were detectable in all HCWs (n: 224). The median Anti-S titers (BAU/mL) was significantly higher in VAI (620 25–75% 373–1341) compared to VO (136, 25–75% 85–283) and IO (111, 25–75% 54–413, p < 0.01). …”
Publicado 2022
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21015por Pasoto, Sandra Gofinet, Halpern, Ari Stiel Radu, Guedes, Lissiane Karine Noronha, Ribeiro, Ana Cristina Medeiros, Yuki, Emily Neves Figueiredo, Saad, Carla Gonçalves Schahin, da Silva, Clovis Artur Almeida, de Vinci Kanda Kupa, Léonard, Villamarín, Lorena Elizabeth Betancourt, de Oliveira Martins, Victor Adriano, Martins, Carolina Campagnoli Machado Freire, Deveza, Giordano Bruno Henriques, Leon, Elaine Pires, Bueno, Cleonice, Pedrosa, Tatiana Nascimento, Santos, Roseli Eliana Beseggio, Soares, Renata, Aikawa, Nádia Emi, Bonfa, Eloisa“…Participants were assessed in three face-to-face visits (D0/D28 and six weeks after the 2nd dose (D69)) regarding adverse effects; clinical EULAR Sjögren’s Syndrome Disease Activity Index (clinESSDAI); anti-SARS-CoV-2 S1/S2 IgG (seroconversion (SC) and geometric mean titers (GMT)); neutralizing antibodies (NAb); and pSS autoantibody profile. …”
Publicado 2022
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21016por Luo, Ji, Brakel, Alexandra, Krizsan, Andor, Ludwig, Tobias, Mötzing, Marina, Volke, Daniela, Lakowa, Nicole, Grünewald, Thomas, Lehmann, Claudia, Wolf, Johannes, Borte, Stephan, Milkovska-Stamenova, Sanja, Gabert, Jörg, Fingas, Felix, Scholz, Markus, Hoffmann, Ralf“…Serum samples from persons with confirmed antibody titers against human immunodeficiency viruses 1/2, parvovirus B19, hepatitis A/B virus, cytomegalovirus, Epstein Barr virus, and herpes simplex virus were tested negative. …”
Publicado 2022
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21017por Garcia-Carbonero, Rocio, Bazan-Peregrino, Miriam, Gil-Martín, Marta, Álvarez, Rafael, Macarulla, Teresa, Riesco-Martinez, Maria C, Verdaguer, Helena, Guillén-Ponce, Carmen, Farrera-Sal, Martí, Moreno, Rafael, Mato-Berciano, Ana, Maliandi, Maria Victoria, Torres-Manjon, Silvia, Costa, Marcel, del Pozo, Natalia, Martínez de Villarreal, Jaime, Real, Francisco X, Vidal, Noemí, Capella, Gabriel, Alemany, Ramon, Blasi, Emma, Blasco, Carmen, Cascalló, Manel, Salazar, Ramon“…Patients were required to have anti-Ad5 neutralizing antibody (NAbs) titers lower than 1/350 dilution. Pharmacokinetic and pharmacodynamic analyses were performed. …”
Publicado 2022
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21018por Malik, Jonaid Ahmad, Aroosa, Mir, Ahmed, Sakeel, Shinde, Mrunal, Alghamdi, Saleh, Almansour, Khaled, Hagbani, Turki Al, Alanazi, Muteb Sultan, Anwar, Sirajudheen“…Many psychological associated things have influenced the vaccine efficacy, like the lower antibody titers in the vaccinated people. In addition to that, Short- and long-term stress and sleep deprivation were also found to affect the vaccine efficacy. …”
Publicado 2022
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21019por Shan, Ying, Gao, Qin, Mao, Junyong, Zheng, Jingyou, Xu, Xiaohan, Zhang, Chuni, Huang, Xiaojun, Xu, Jidong, Shi, Fushan, Yue, Min, He, Fang, Fang, Weihuan, Li, Xiaoliang“…In conclusion, both S1-ELISA and S1T2-ELISA can be used as candidate systems for detecting anti-PEDV IgA antibody titers in serum, which can reflect the level of neutralizing activity in pigs after natural infection or vaccination. …”
Publicado 2022
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21020por Deschambault, Yvon, Lynch, Jessie, Warner, Bryce, Tierney, Kevin, Huynh, Denise, Vendramelli, Robert, Tailor, Nikesh, Frost, Kathy, Sajesh, Babu, LeBlanc, Kyle, Layne, Christine, Lin, Lisa, Tamming, Levi, Beniac, Daniel, Booth, Stephanie, Carpenter, Michael, Safronetz, David, Li, Xuguang, Kobasa, Darwyn, Cao, Jingxin“…The protection was associated with reduced viral loads, increased neutralizing antibody titer, and reduced neutrophil-to-lymphocyte ratio. …”
Publicado 2022
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