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21021Nanoparticle-delivered TLR4 and RIG-I agonists enhance immune response to SARS-CoV-2 subunit vaccinepor Atalis, Alexandra, Keenum, Mark C., Pandey, Bhawana, Beach, Alexander, Pradhan, Pallab, Vantucci, Casey, O'Farrell, Laura, Noel, Richard, Jain, Ritika, Hosten, Justin, Smith, Clinton, Kramer, Liana, Jimenez, Angela, Ochoa, Miguel Armenta, Frey, David, Roy, Krishnendu“…MPLA+PUUC NPs further boosted spike protein-neutralizing antibody titers and T follicular helper cell populations in the dLNs. …”
Publicado 2022
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21022por Peled, Yael, Afek, Arnon, Kreiss, Yitshak, Rahav, Galia, Nemet, Ital, Kliker, Limor, Indenbaum, Victoria, Ram, Eilon, Lavee, Jacob, Segev, Amit, Matezki, Shlomi, Sternik, Leonid, Raanani, Ehud, Lustig, Yaniv, Patel, Jignesh K., Mandelboim, Michal“…RESULTS: The third dose induced high neutralization of the wild-type virus and delta variant (geometric mean titer [GMT], 137.2 [95% CI, 84.8-221.9] and 80.6, [95% CI, 49.3-132.0], respectively), and to a lesser degree of the omicron variant (GMT, 10.3 [95% CI, 5.9-17.9]). …”
Publicado 2022
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21023por Seok, Hyeri, Españo, Erica, Kim, Jooyun, Jeon, Ji Hoon, Choi, Won Suk, Kim, Yun-Kyung, Kim, Jeong-Ki, Park, Dae Won“…The median neutralizing antibody titer was highest in Group 1, and this was significantly different from that in Group 2 or Group 3 at 4 weeks (944 vs. 405 vs. 482 mIU/mL, P = 0.001) and 6 months (826 vs. 401 vs. 470, P = 0.011) after ORI. …”
Publicado 2022
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21024por Banihashemi, Seyed Reza, Es-haghi, Ali, Fallah Mehrabadi, Mohammad Hossein, Nofeli, Mojtaba, Mokarram, Ali Rezaei, Ranjbar, Alireza, Salman, Mo, Hajimoradi, Monireh, Razaz, Seyad Hossein, Taghdiri, Maryam, Bagheri, Mohsen, Dadar, Maryam, Hassan, Zuhair Mohammad, Eslampanah, Mohammad, Salehi Najafabadi, Zahra, Lotfi, Mohsen, Khorasani, Akbar, Rahmani, Fereidoon“…Three different doses of candidate vaccine stimulated remarkable titers of neutralizing antibodies, S1, Receptor-Binding Domain (RBD), and N-terminal domain (NTD) specific IgG antibodies as well as IgA antibodies compared to placebo and control groups (P<0.01). …”
Publicado 2022
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21025por Nagasaki, Naoko, Ito, Masanori, Boda, Tomoyuki, Kotachi, Takahiro, Takigawa, Hidehiko, Oka, Shiro, Tanaka, Shinji“…The serum pepsinogen (PG) levels and anti-Helicobacter pylori antibody (Hp-Ab) titers were evaluated in each patient. The enrolled patients were matched with the database of the Hiroshima Prefecture Regional Cancer Registry. …”
Publicado 2022
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21026“…The critical issue of the competitiveness between bioengineering and chemical engineering is products titer and volume productivity. Therefore, based on the importance of hydroxyl acids in many fields, exploring a clean, practical and environmental-friendly preparation process of the hydroxyl acids is the core purpose of this study. …”
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21027por Munnagi, Ashwini, Pillai, Vijay, Bushan, R. Vidhya, Shetty, Vivek, Subramaniam, Narayana, Shivaprasad, K. S., Khadilkar, Kranti, Sooragonda, Basavaraj G., Lakhsmikantha, Akhila, Rekha, Pobbisetty Radhakrishnagupta, Zaidi, Shaesta Naseem, Batra, Nishtha, Kannan, Subramanian“…As of last follow-up, none of them underwent completion thyroidectomy; however, eight patients had a decline in Tg ranging from 8 to 64%, four patients had increase in Tg ranging from 14 to 145%, three patients had stable Tg, and one of them had an increase in TgAb titers. As per American Thyroid Association (ATA) response-to-treatment category, six patients had indeterminate response, five patients had biochemical incomplete response, four patients had excellent response, and two did not have follow-up Tg and TgAb levels. …”
Publicado 2021
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21028por Mahmoud, Sherif I. A., Zyan, Kamel A., Hamoud, Mohamed M., Khalifa, Eman, Dardir, Shahin, Khalifa, Rabab, Kilany, Walid H., Elfeil, Wael K.“…The recorded results revealed a significant decrease in clinical manifestations and virus shedding in terms of titers of shedding virus and number of shedders in vaccinated compared to non-vaccinated chickens. …”
Publicado 2022
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21029por Pimentel, Raquel, Correia, Catarina, Estorninho, João, Gravito-Soares, Elisa, Gravito-Soares, Marta, Figueiredo, Pedro“…A STI screening was positive for HIV-1 (CD4+ 251/mm<sup>3</sup>; N = 700–1,100) and C. trachomatis, with an elevated IgA-specific antibody titer (52.000; N < 5.0), suggesting LGV disease. …”
Publicado 2021
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21030por Muñoz-Fernández, Gloria, Martínez-Buey, Rubén, Revuelta, José Luis, Jiménez, Alberto“…In addition, the utilization of the orthogonal pathway, bypassing the Erg20 activity through neryl diphosphate, triggered a substantial increase in limonene titer (33.6 mg/L), without critically altering the fitness of the engineered strain. …”
Publicado 2022
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21031COVID-19 booster dose induces robust antibody response in pregnant, lactating, and nonpregnant womenpor Atyeo, Caroline, Shook, Lydia L., Nziza, Nadege, Deriso, Elizabeth A., Muir, Cordelia, Baez, Arantxa Medina, Lima, Rosiane S., Demidkin, Stepan, Brigida, Sara, De Guzman, Rose M., Burns, Madeleine D., Balazs, Alejandro B., Fasano, Alessio, Yonker, Lael M., Gray, Kathryn J., Alter, Galit, Edlow, Andrea G.“…Pregnant and lactating individuals exhibited equivalent Spike-specific total immunoglobulin G1, immunoglobulin M, and immunoglobulin A levels and neutralizing titers against Omicron compared with nonpregnant women. …”
Publicado 2023
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21032por Motamedi Sedeh, Farahnaz, Khalili, Iraj, Wijewardana, Viskam, Unger, Hermann, Shawrang, Parvin, Behgar, Mehdi, Moosavi, Sayed Morteza, Arbabi, Arash, Hosseini, Sayedeh Maede“…The results of the HI test showed significant increases in antibody titer in all vaccinated groups, but it was more evident in the IVT late vaccination regime, reaching 5.33 log(2). …”
Publicado 2022
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21033por Kimura, Muneyoshi, Ferreira, Victor H., Kothari, Sagar, Pasic, Ivan, Mattsson, Jonas I., Kulasingam, Vathany, Humar, Atul, Mah, Allison, Delisle, Jean-Sébastien, Ierullo, Matthew, Majchrzak-Kita, Beata, Kumar, Deepali, Hosseini-Moghaddam, Seyed M.“…In immunogenicity analysis (n = 95), the median (interquartile range [IQR]) antibody titer against the receptor-binding domain (RBD) of the spike (S) protein after the third dose (10,358.0 U/mL [IQR = 673.9-31,753.0]) was significantly higher than that after the first (10.2 U/mL [IQR = 0.6-37.0]) and the second doses (125.6 U/mL [IQR = 2.8-1251.0]) (P < .0001). …”
Publicado 2022
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21034por Abdolkarimi, Babak, Amanati, Ali, Molavi Vardanjani, Hossein, Jamshidi, Safura, Tabaeian, Seid Amir Pasha“…The patient’s blood samples were obtained, and serum IgG antibody titer checked against diphtheria, tetanus, hepatitis B virus (HBV), mumps, measles, and rubella (MMR) were measured by enzyme-linked immunosorbent assay (ELISA). …”
Publicado 2022
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21035por Artiaga, Bianca L., Morozov, Igor, Ransburgh, Russell, Kwon, Taeyong, Balaraman, Velmurugan, Indran, Sabarish V., De Carvalho Madrid, Darling Melany, Gu, Weihong, Henningson, Jamie, Ma, Wenjun, Richt, Jürgen A., Driver, John P.“…On the other hand, combining the vaccine with α-GalCer reduced cross-protective cellular and antibody responses, and resulted in higher virus titers in respiratory tissues. These findings suggest that: (i) high doses of α-GalCer impair the replication and nasal shedding of the LAIV vaccine; and (ii) α-GalCer might interfere with heterosubtypic cross-protective immune responses. …”
Publicado 2022
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21036por Syversen, Silje W., Jyssum, Ingrid, Tveter, Anne T., Tran, Trung T., Sexton, Joseph, Provan, Sella A., Mjaaland, Siri, Warren, David J., Kvien, Tore K., Grødeland, Gunnveig, Nissen‐Meyer, Lise S. H., Ricanek, Petr, Chopra, Adity, Andersson, Ane M., Kro, Grete B., Jahnsen, Jørgen, Munthe, Ludvig A., Haavardsholm, Espen A., Vaage, John T., Lund‐Johansen, Fridtjof, Jørgensen, Kristin K., Goll, Guro L.“…Patients with a weak serologic response, defined as an IgG antibody titer of ≤100 arbitrary units per milliliter (AU/ml) against the receptor‐binding domain of the full‐length SARS–Cov‐2 spike protein, were allotted a third vaccine dose. …”
Publicado 2022
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21037por Wang, Yanshuang, Li, Xuemiao, Dance, David A. B., Xia, Han, Chen, Chen, Luo, Nini, Li, Anyang, Li, Yanmei, Zhu, Qiao, Sun, Qinghui, Wu, Xingyong, Zeng, Yingfei, Chen, Lin, Tian, Shen, Xia, Qianfeng“…Under the optimal multiplicity of infection (MOI) of 0.1, an eclipse period of around 20 min and a high titer (10(12) PFU/ml) produced within 1 h were demonstrated. …”
Publicado 2022
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21038por Teeyapun, Nattaya, Luangdilok, Sutima, Pakvisal, Nussara, Sainamthip, Panot, Mingmalairak, Siyamol, Poovorawan, Nattaya, Sitthideatphaiboon, Piyada, Parinyanitikul, Napa, Sriuranpong, Virote, Namkanisorn, Teerayuth, Inthasuwan, Pratchaya, Angspatt, Pattama, Wongchanapat, Ploytuangporn, Bamrungnam, Akradach, Leeleakpai, Nutchanok, Uttha, Sutheera, Jaichum, Supaporn, Kongkaew, Peerawich, Suksanong, Chayanin, Veranitinun, Rattiya, Prasomphol, Ampai, Sartsuk, Chada, Patcharajutanon, Cheeraporn, Preaprang, Supreeya, Choengsamor, Hathairat, Phongwan, Rungthong, Preeyasaksa, Charoenpit, Phaibulvatanapong, Ekkamol, Suntronwong, Nungruthai, Yorsaeng, Ritthideach, Vichaiwattana, Preeyaporn, Wanlapakorn, Nasamon, Kerr, Stephen J., Poovorawan, Yong, Wanchaijiraboon, Passakorn, Tanasanvimon, Suebpong“…The primary endpoint was the geometric mean titers (GMT) of antibody among solid cancer patients compared to healthy controls and the impact of different cancer treatment types. …”
Publicado 2022
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21039por Wang, Bihua, Zhu, Zhidan, Huang, Feng, Huang, Haowen, Tu, Luxia, Wang, Ying, Zheng, Linfeng, Zhou, Jing, Wei, Xin“…All patients were divided into two groups according to anti-PLA2R antibody titer at diagnosis: high-level group (> 150 RU/ml; n = 42) and low-level group (≤ 150 RU/ml; n = 52). …”
Publicado 2022
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21040por Zou, Peicen, Yang, Fan, Ding, Yijun, Zhang, Di, Liu, Ying, Zhang, Jinjing, Wu, Dan, Wang, Yajuan“…After LPS stimulation, p-Akt protein increased at 2 h and peaked at 4 h. The titer of p-PI3K did not change significantly with time. …”
Publicado 2022
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