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21061por Guan, Zhixin, Pang, Linlin, Ouyang, Yan, Jiang, Yifeng, Zhang, Junjie, Qiu, Yafeng, Li, Zongjie, Li, Beibei, Liu, Ke, Shao, Donghua, Ma, Zhiyong, Wei, Jianchao“…Necropsy data showed that coinfected piglets suffered from severe lung damage and had significantly higher antibody titers of HP-PRRSV2 or Gps than single-infected piglets. …”
Publicado 2023
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21062por Wang, Xiao, Tang, Jingjing, Dang, Wen, Xie, Zhen, Zhang, Fuhua, Hao, Xinwei, Sun, Sihuai, Liu, Xuan, Luo, Yi, Li, Mengyuan, Gu, Yanchao, Wang, Yao, Chen, Qiwei, Shen, Xihui, Xu, Lei“…One-step growth curves showed that the burst size of PA_LZ01 was 15 PFU/infected cell, and that of PA_LZ02 was 50 PFU/infected cell, while the titer of PA_LZ03 was not elevated. Similarly, the biofilm clearance capacities of PA_LZ01 and PA_LZ02 were also higher than that of PA_LZ03. …”
Publicado 2023
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21063por Kim, Eun, Khan, Muhammad S., Ferrari, Alessandro, Huang, Shaohua, Sammartino, Josè C., Percivalle, Elena, Kenniston, Thomas W., Cassaniti, Irene, Baldanti, Fausto, Gambotto, Andrea“…In this follow-up study, we found that the mice had high titers of anti-S1 antibodies 1 year after vaccination, and one booster dose of the nonadjuvanted rS1Beta (recombinant S1 protein of SARS-CoV-2 Beta [B.1.351]) subunit vaccine was effective at stimulating strong long-lived S1-specific immune responses and inducing significantly high neutralizing antibodies against Wuhan, Beta, and Delta strains, with 3.6- to 19.5-fold increases. …”
Publicado 2023
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21064por Aguirre, Alex S, Vivanco, Ricardo A, Ortiz, Juan Fernando, Rozen, Valery, InsuastI, Walter E, Fiallos, John, Gallegos, Camila, Villavicencio, Andrea, Salazar, Kevin, Duenas, Francisco, Singla, Ramit“…The biological response was assessed by measuring the decrease in antibody titers in 27 patients. Among those, six patients had CR, 12 had PR, eight had SD, and one had progression. …”
Publicado 2023
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21065por Maglione, Alessandro, Francese, Rachele, Arduino, Irene, Rosso, Rachele, Matta, Manuela, Rolla, Simona, Lembo, David, Clerico, Marinella“…Anti-Region Binding Domain (anti-RBD) of the spike (S) protein immunoglobulin G (IgG) titers were measured by ELISA. The neutralization efficacy of collected sera was measured by SARS-CoV-2 pseudovirion-based neutralization assay. …”
Publicado 2023
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21066por Martin Aispuro, Pablo, Bottero, Daniela, Zurita, María Eugenia, Gaillard, María Emilia, Hozbor, Daniela Flavia“…Pertussis toxin (PTx)-specific IgG responses were detected in mothers after both the second and third doses, with higher titers after the third dose, regardless of the vaccination schedule. …”
Publicado 2023
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21067por Duan, Weiwei, Jiang, Fei, Cai, Haobing, Li, Bijuan, Ouyang, Song, Yin, Weifan, Zeng, Qiuming, Yang, Huan“…Compared to PE, LPE was superior in the reduction of AChR-Ab titer. CONCLUSION: In severe MG, LPE may be a more preferred treatment option than PE. …”
Publicado 2023
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21068por Mercure-Corriveau, Nicolas, Roy, Shuvro, Hu, Chen, Crowe, Elizabeth P., Zhu, Xianming, Obando, Danielle, Patel, Eshan U., Tobian, Aaron A. R., Wang, Yujie, Bloch, Evan M., Newsome, Scott D.“…RESULTS: Thirty-nine SPSD patients were treated with TPE (21 at JHH and 18 at outside institutions); median age 48 years, 77% female, median modified Rankin Scale 3; mean initial anti-GAD65 antibody titer was 23,508 U/mL. Twenty-four patients (62%) had classic SPS, 10 (26%) had SPS-plus, 2 (5%) had progressive encephalomyelitis with rigidity and myoclonus, and 3 (8%) had pure cerebellar ataxia. …”
Publicado 2023
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21069por Boelig, Rupsa C., Chaudhury, Sidhartha, Gromowski, Gregory D., Mayer, Sandra, King, Jocelyn, Aghai, Zubair H., Bergmann-Leitner, Elke“…RESULTS: Pregnant women with COVID-19 vaccination had a greater spike in IgG titers compared to both those with COVID-19 disease exposure and controls. …”
Publicado 2023
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21070por Aymée, Luiza, Di Azevedo, Maria Isabel Nogueira, Reis, Luiza, Mendes, Julia, de Castro, Fúlvia de Fátima Almeida, Carvalho-Costa, Filipe Anibal, de Souza, Guilherme Nunes, Lilenbaum, Walter“…Results: The herd presented seroreactive animals (11/30, 36.6%), all against the Sejroe serogroup, with titers between 200 and 1600. In necropsy, four fetuses showed hemorrhagic and anicteric lesions, while one fetus had no macroscopic lesions. …”
Publicado 2023
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21071“…Our plan is to monitor his C-peptide titers and test his insulin antibodies. Evidence suggests that PHPT may cause insulin resistance and glucose intolerance. …”
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21072por Scarpa, Riccardo, Piazza, Maria, Caroccia, Brasilina, Carraro, Samuela, Vianello, Fabrizio, Cinetto, Francesco, Agostini, Carlo, Seccia, Teresa M, Paolo Rossi, Gian“…Primary Aldosteronism, the paradigm of salt-dependent hypertension, is characterised by a more prominent HMOD than primary (‘essential’) hypertension and by high titer of autoantibodies against the type 1 angiotensin receptor (AT1R). …”
Publicado 2023
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21073“…These patients showed lower HBsAg titers and serum HBV-DNA levels (p = 0.048, p = 0.036). …”
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21074por Rodríguez-Mora, Sara, Corona, Magdalena, Solera Sainero, Miriam, Mateos, Elena, Torres, Montserrat, Sánchez-Menéndez, Clara, Casado-Fernández, Guiomar, García-Pérez, Javier, Pérez-Olmeda, Mayte, Murciano-Antón, María Aranzazu, López-Jiménez, Javier, Coiras, Mayte, García-Gutiérrez, Valentín“…All CML individuals developed an increased humoral response, with similar seroconversion rates and neutralizing titers to healthy donors, despite the presence of high levels of immature B cells. …”
Publicado 2023
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21075por Ardanuy, Jeremy, Johnson, Robert, Dillen, Carly, Taylor, Louis, Hammond, Holly, Weston, Stuart, Frieman, Matthew“…Additionally, we found that pyronaridine treatment can safely and effectively be combined with currently used therapeutics molnupiravir and nirmatrelvir (main protease inhibitor component of Paxlovid) in a SARS-CoV-2 in vivo model, and there was evidence of a synergistic effect that further reduced viral titers, inflammatory lung pathology, and inflammatory cytokine and chemokine levels. …”
Publicado 2023
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21076por Zhu, Deanna R., Rajesh, Alecia J., Meganck, Rita M., Young, Ellen F., Munt, Jennifer E., Tse, Victor L., Yount, Boyd, Conrad, Helen, White, Laura, Henein, Sandra, DeSilva, Aravinda M., Baric, Ralph S.“…Sera from natural infection had a unique neutralization pattern compared to sera from human challenge, which included greater frequency and higher titer of responses against DENV EDII. In summary, DENV4/2 E recombinant viruses delineate the subdomain targets of TS antibodies after vaccination and primary infection, which may provide new correlates of protection or identify epitopes of neutralizing monoclonal antibodies. …”
Publicado 2023
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21077por Luo, Xia, Fu, Xiaozhe, Zhang, Min, Liang, Hongru, Niu, Yinjie, Lin, Qiang, Ma, Baofu, Liu, Lihui, Li, Ningqiu“…For virology study, the RSBB cells were highly susceptible to Nervous necrosis virus (NNV) and Singapore grouper iridovirus (SGIV) with steady titers (i.e., 10(8.0~8.3) TCID(50) mL(−1) and 10(7.0~7.2) TCID(50) mL(−1) respectively). …”
Publicado 2023
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21078por Sobhani, Kimia, Cheng, Susan, Binder, Raquel A., Mantis, Nicholas J., Crawford, James M., Okoye, Nkemakonam, Braun, Jonathan G., Joung, Sandy, Wang, Minhao, Lozanski, Gerard, King, Christopher L., Roback, John D., Granger, Douglas A., Boppana, Suresh B., Karger, Amy B.“…Herein, we review established clinical use cases for SARS-CoV-2 antibody measures, which include diagnosis of recent prior infection, isolating high titer convalescent plasma, diagnosing multisystem inflammatory syndrome in children (MIS-C), and booster dosing in the immunosuppressed and other populations. …”
Publicado 2023
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21079por Robertson, Corwin A, Galarza, Katherine, Jacqmein, Jeffry, Selmani, Alexandre, Oster, Philipp“…At 5 years post-primary vaccination, seroprotection (hSBA ≥ 1:8) rates (SPRs) and hSBA geometric mean titers (GMTs) declined in both MenACYW-TT- and MPSV4-primed subjects, with SPRs and hSBA GMTs for serogroups A, C, W, and Y trending higher in MenACYW-TT- vs MPSV4-primed subjects (Table 1). …”
Publicado 2023
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21080“…We used the chi-square test to compare seropositivity between groups and SPSS version 28 for statistical analysis. CF titers ≥ 1:8 were considered positive. RESULTS: 901 serum CV-A tests were performed in 263 patients (median age 42, range 3-89) among whom 6 (2.3%) were positive for at least one serotype. …”
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