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  1. 21421
    “…Patients were included if they were ≥18 years of age, with at least two outpatient encounters with primary care provider or endocrinologist within the past 18 months, along with an active diagnosis of T1D (ICD-9 or -10 code) on their problem list, or at least 2 encounter diagnosis for T1D in the past 18 months, or documentation of a positive glutamic acid decarboxylase (GAD)-65 antibody titer. Categorical and continuous variables were summarized using N (%) and median (IQR), respectively. …”
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    PSUN92 Type 1 Diabetes and Obesity: The Overlooked Epidemic
  2. 21422
    “…We describe 2 cases from our endocrine clinic with significant zinc 8 transporter antibody titers over 8 - 26 years after their initial diagnosis. …”
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    PSAT232 Understanding the Duration of Zinc 8 Transporter Antibody Seropositivity
  3. 21423
    “…In Group A, the reason for LT4-Rx, LT4 dose, LT4 dose/BMI, TSH levels and the presence of increased thyroid autoantibodies titers (ATA) were significantly different in those who became hypothyroid, whereas only the reason for LT4-Rx differed in Group B. …”
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    LBSAT247 Factors Guiding Successful Treatment Discontinuation In Levothyroxine Replacement Therapy Overuse: Short And Long-term Observation Data Of 802 Subjects.
  4. 21424
    “…Renin activity was repeated and was elevated again at 34ng/ml/hr, prompting adrenal antibody testing, which revealed an elevated titer 1: 10 (<1: 10). Due to concern for APS-1, genetic testing was obtained and revealed a pathological variant of AIRE of c.892G>A and c.967_979del consistent with APS-1. …”
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    PMON317 Rapid Progression of Adrenal insufficiency in Child with Autoimmune Polyendocrine Syndrome Type 1
  5. 21425
    “…Moreover, a low-level titer of neutralizing antibodies against the Omicron BA.2 subvariant could be found in only one seropositive tiger. …”
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    Serological and Molecular Surveillance for SARS-CoV-2 Infection in Captive Tigers (Panthera tigris), Thailand
  6. 21426
    “…Immunized+P3C4-1 µg group had reduced levels of IgG1, IgG2a and IgA and no significant difference in the IgG and IgM anti-GXM antibody titer was detected, compared to the Immunized group. …”
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    Adjuvant Pam3CSk4 does not improve the immunization against Cryptococcus gattii infection in C57BL/6 mice
  7. 21427
    “…When using the cutoff of 1000 copies/ml, 5000 copies/ml and 10,000 copies/ml for plasma EBV DNA titer, baseline low plasma EBV DNA was consistently related with better DCR, PFS and OS. …”
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    Efficacy and safety of KL-A167 in previously treated recurrent or metastatic nasopharyngeal carcinoma: a multicenter, single-arm, phase 2 study
  8. 21428
    “…There were no significant differences in S1-RBD antibody titers between the CoronaVac (2x) + BNT162b2 (1x) and BNT162b2 (3x) groups. …”
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    Humoral immunity against SARS-CoV-2 evoked by heterologous vaccination groups using the CoronaVac (Sinovac) and BNT162b2 (Pfizer/BioNTech) vaccines in Chile
  9. 21429
    “…In patients with prostate cancer, there was a significant increase in ELISPOT response against hTERT peptide pool 2 following immunization (p < 0.01), regardless of previous therapy, immunosuppressing agents, or adenoviral type 6 titers at screening. CONCLUSION: Our results suggest the safety and feasibility of V934/V935 hTERT vaccination in cancer patients with solid tumors Trial Registration Name of the registry: ClinicalTrial.gov Trial registration number: NCT00753415 Date of registration: 16 September 2008 Retrospectively registered URL of trial registry record: https://clinicaltrials.gov/ct2/results?…”
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    Safety, tolerability and immunogenicity of V934/V935 hTERT vaccination in cancer patients with selected solid tumors: a phase I study
  10. 21430
    “…Here, we evaluated modulatory effects of curcumin-primed human (h)BMSC-derived EVs (Cur-EVs) on IL-1β stimulated human osteoarthritic chondrocytes (OA-CH). METHODS: CellTiter-Blue Viability- (CTB), Caspase 3/7-, and live/dead assays were used to determine range of cytotoxic curcumin concentrations for hBMSC and OA-CH. …”
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    Curcumin-primed human BMSC-derived extracellular vesicles reverse IL-1β-induced catabolic responses of OA chondrocytes by upregulating miR-126-3p
  11. 21431
    “…The passage no.1–3 (P1-3) of E191A grew to very low titers in Vero cells. To evaluate the pathogenesis of the E191A, 4 or 5-day-old gnotobiotic pigs were inoculated orally with 100 TCID(50)/pig of the E191A-P1, icPC22A, or mock. …”
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    Crucial mutation in the exoribonuclease domain of nsp14 of PEDV leads to high genetic instability during viral replication
  12. 21432
    “…Vaccination of seropositive (N=14) volunteers rapidly boosted RBD-specific IgGs from reciprocal geometric mean titer (​GMT) 594·4 at a baseline up to 26899 comparing to 29·09 in seronegative group (N=96) by day 10. …”
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    An open, non-randomised, phase 1/2 trial on the safety, tolerability, and immunogenicity of single-dose vaccine “Sputnik Light” for prevention of coronavirus infection in healthy adults
  13. 21433
    “…The effects of Fos and ARRDC3 on virus replication were confirmed using RT-qPCR, virus titer (TCID(50)/ml), Western blotting. RESULTS: 375 lncRNAs (154 upregulated and 221 downregulated), 33 circRNAs (32 upregulated and 1 downregulated), 96 miRNAs (49 upregulated and 47 downregulated), and 239 mRNAs (135 upregulated and 104 downregulated) were identified as differently in infected group compare to no-infected group. …”
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    High throughput sequencing of whole transcriptome and construct of ceRNA regulatory network in RD cells infected with enterovirus D68
  14. 21434
    “…One month after the second dose, the geometric mean ratio of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing titers in 5-to-11-year-olds to those in 16-to-25-year-olds was 1.04 (95% confidence interval [CI], 0.93 to 1.18), a ratio meeting the prespecified immunogenicity success criterion (lower bound of two-sided 95% CI, >0.67; geometric mean ratio point estimate, ≥0.8). …”
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    Evaluation of the BNT162b2 Covid-19 Vaccine in Children 5 to 11 Years of Age
  15. 21435
    “…Seropositivity rates of neutralizing antibodies in the population evaluated were over 97% for the lineage B strain, over 80% for Alpha and Gamma variants, over 75% for Delta variant and over 60% for the Beta variant. Geometric means titers of blocking antibodies were reduced when tested against SARS-CoV-2 variants as compared to ancestral strain. …”
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    Recognition of Variants of Concern by Antibodies and T Cells Induced by a SARS-CoV-2 Inactivated Vaccine
  16. 21436
    por Rojas, Manuel, Rodríguez, Yhojan, Hernández, Juan Carlos, Díaz-Coronado, Juan C., Vergara, José Alejandro Daza, Vélez, Verónica Posada, Mancilla, Jessica Porras, Araujo, Iván, Yepes, Jairo Torres, Ricaurte, Oscar Briceño, Pardo-Oviedo, Juan Mauricio, Monsalve, Diana M., Acosta-Ampudia, Yeny, Ramírez-Santana, Carolina, García, Paula Gaviria, Landinez, Lina Acevedo, Correales, Luisa Duarte, Grass, Jeser Santiago, Pérez, Cristian Ricaurte, López, Gustavo Salguero, Mateus, Nataly, Mancera, Laura, Devia, Ronald Rengifo, Orjuela, Juan Esteban, Parra-Moreno, Christian R., Buitrago, Andrés Alfonso, Ordoñez, Inés Elvira, Osorio, Claudia Fabra, Ballesteros, Nathalia, Patiño, Luz H., Castañeda, Sergio, Muñoz, Marina, Ramírez, Juan David, Bastard, Paul, Gervais, Adrian, Bizien, Lucy, Casanova, Jean-Laurent, Camacho, Bernardo, Gallo, Juan Esteban, Gómez, Oscar, Rojas-Villarraga, Adriana, Pérez, Carlos E., Manrique, Rubén, Mantilla, Rubén D., Anaya, Juan-Manuel
    Publicado 2022
    “…All transfused plasma was obtained from "super donors" that fulfilled the following criteria: titers of anti-SARS-CoV-2 S1 IgG ≥ 1:3200 and IgA ≥ 1:800 antibodies. …”
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    Safety and efficacy of convalescent plasma for severe COVID-19: a randomized, single blinded, parallel, controlled clinical study
  17. 21437
    “…RESULTS: Individuals infected by the B.1214.1 variant elicited consistently high IgG titers at 02, 03 and 06 months. Two months post vaccination with BBIP-CorV, participants showed a significant increase by × 2.5 fold (p < 0.0001) of total IgG and X1.5 fold for neutralizing antibody capacity. …”
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    Assessment of neutralizing antibody responses after natural SARS-CoV-2 infection and vaccination in congolese individuals
  18. 21438
    “…In patients on anti-CD20 therapy, higher spike antibody levels were associated with higher CD20 cell count (p<0.001), and longer time since last anti-CD20 therapy infusion (p<0.001). 92.8% (13/14) vaccine responders (spike antibody titer >100 ug/dL) on anti-CD20 therapy demonstrated B-cell reconstitution (mean CD20 3.6%). …”
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    Humoral response to COVID-19 vaccination in MS patients on disease modifying therapy: Immune profiles and clinical outcomes
  19. 21439
    “…METHODS: CD20 B cell depleted autoimmune patients and age/sex-matched controls positive for SARS-CoV-2 were recruited at Dell Medical School, UT Austin between 2020 and 2021, followed prospectively for 12 months and evaluated at multiple time points for spike S1 receptor binding domain (RBD) antibody titers, B and T cell composition, and frequency of T cells specific for SARS-CoV-2 antigens. …”
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    Longitudinal COVID-19 immune trajectories in patients with neurological autoimmunity on anti-CD20 therapy
  20. 21440
    “…The rPvRAMA protein induced antibody responses, with the end-point titer ranging from 1:10,000 to 1:5,120,000. IgG1 was the predominant IgG subclass in rPvRAMA-immunized mice, followed by IgG2b. …”
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    Immunogenicity and antigenicity of a conserved fragment of the rhoptry-associated membrane antigen of Plasmodium vivax
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