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2521por Yadava, Anjali, Hall, Cysha E., Sullivan, JoAnn S., Nace, Douglas, Williams, Tyrone, Collins, William E., Ockenhouse, Christian F., Barnwell, John W.“…The protected monkeys had a median anti-repeat titer of 97,841 compared to 14,822 in the non-protected monkeys. …”
Publicado 2014
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2522“…Under the above conditions, the α-ketoisocaproate titer reached 12.7 g/L with a leucine conversion rate of 97.8%. …”
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2523por Cao, Weijia, Ma, Weichao, Wang, Xin, Zhang, Bowen, Cao, Xun, Chen, Kequan, Li, Yan, Ouyang, Pingkai“…With a two-phase pH fermentation strategy, the cultivation of the optimized strain resulted in a final pinocembrin titer of 67.81 mg/L. The results and engineering strategies demonstrated here would hold promise for the titer improvement of other flavonoids.…”
Publicado 2016
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2524por Walters, Kathie-Anne, Zhu, Ruoqing, Welge, Michael, Scherler, Kelsey, Park, Jae-Keun, Rahil, Zainab, Wang, Hao, Auvil, Loretta, Bushell, Colleen, Lee, Min Young, Baxter, David, Bristol, Tyler, Rosas, Luz Angela, Cervantes-Medina, Adriana, Czajkowski, Lindsay, Han, Alison, Memoli, Matthew J., Taubenberger, Jeffery K., Kash, John C.“…In this study, we examined the relationships between anti-influenza virus serum antibody titers, clinical disease, and peripheral blood leukocyte (PBL) global gene expression during presymptomatic, acute, and convalescent illness in 83 participants infected with 2009 pandemic H1N1 virus in a human influenza challenge model. …”
Publicado 2019
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2525por Postnikova, Elena N., Pettitt, James, Van Ryn, Collin J., Holbrook, Michael R., Bollinger, Laura, Yú, Shuǐqìng, Caì, Yíngyún, Liang, Janie, Sneller, Michael C., Jahrling, Peter B., Hensley, Lisa E., Kuhn, Jens H., Fallah, Mosoka P., Bennett, Richard S., Reilly, Cavan“…Antibody titers against a viral pathogen are typically measured using an antigen binding assay, such as an enzyme-linked immunosorbent assay (ELISA), which only measures the ability of antibodies to identify a viral antigen of interest. …”
Publicado 2019
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2526“…Sera of cats which were clinically and serologically diagnosed as feline infectious peritonitis (FIP) possessed significantly higher VN titers to type I FCoV, and sera from cats experimentally infected with FIPV type II had high VN titers to type II but not type I viruses. …”
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2527por Ng, Dianna L., Goldgof, Gregory M., Shy, Brian R., Levine, Andrew G., Balcerek, Joanna, Bapat, Sagar P., Prostko, John, Rodgers, Mary, Coller, Kelly, Pearce, Sandra, Franz, Sergej, Du, Li, Stone, Mars, Pillai, Satish K., Sotomayor-Gonzalez, Alicia, Servellita, Venice, Martin, Claudia Sanchez San, Granados, Andrea, Glasner, Dustin R., Han, Lucy M., Truong, Kent, Akagi, Naomi, Nguyen, David N., Neumann, Neil M., Qazi, Daniel, Hsu, Elaine, Gu, Wei, Santos, Yale A., Custer, Brian, Green, Valerie, Williamson, Phillip, Hills, Nancy K., Lu, Chuanyi M., Whitman, Jeffrey D., Stramer, Susan L., Wang, Candace, Reyes, Kevin, Hakim, Jill M. C., Sujishi, Kirk, Alazzeh, Fariba, Pham, Lori, Thornborrow, Edward, Oon, Ching-Ying, Miller, Steve, Kurtz, Theodore, Simmons, Graham, Hackett, John, Busch, Michael P., Chiu, Charles Y.“…Neutralizing antibodies rose in tandem with immunoglobulin titers following symptom onset, and positive percent agreement between detection of IgG and neutralizing titers was >93%. …”
Publicado 2020
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2528por Li, Cesheng, Yu, Ding, Wu, Xiao, Liang, Hong, Zhou, Zhijun, Xie, Yong, Li, Taojing, Wu, Junzheng, Lu, Fengping, Feng, Lu, Mao, Min, Lin, Lianzhen, Guo, Huanhuan, Yue, Shenglan, Wang, Feifei, Peng, Yan, Hu, Yong, Wang, Zejun, Yu, Jianhong, Zhang, Yong, Lu, Jia, Ning, Haoran, Yang, Huichuan, Fu, Daoxing, He, Yanlin, Zhou, Dongbo, Du, Tao, Duan, Kai, Dong, Demei, Deng, Kun, Zou, Xia, Zhang, Ya, Zhou, Rong, Gao, Yang, Zhang, Xinxin, Yang, Xiaoming“…Moreover, male plasma donors produce more RBD-IgG than female, and age of the patients positively correlates with the RBD-IgG titer. A strong positive correlation between RBD-IgG and neutralizing antibody titers is also identified. …”
Publicado 2021
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2529por Gorman, Matthew J., Patel, Nita, Guebre-Xabier, Mimi, Zhu, Alex L., Atyeo, Caroline, Pullen, Krista M., Loos, Carolin, Goez-Gazi, Yenny, Carrion, Ricardo, Tian, Jing-Hui, Yuan, Dansu, Bowman, Kathryn A., Zhou, Bin, Maciejewski, Sonia, McGrath, Marisa E., Logue, James, Frieman, Matthew B., Montefiori, David, Mann, Colin, Schendel, Sharon, Amanat, Fatima, Krammer, Florian, Saphire, Erica Ollmann, Lauffenburger, Douglas A., Greene, Ann M., Portnoff, Alyse D., Massare, Michael J., Ellingsworth, Larry, Glenn, Gregory, Smith, Gale, Alter, Galit“…However, with the variety of vaccines, immunization strategies, and waning antibody titers, defining the correlates of immunity across a spectrum of antibody titers is urgently required. …”
Publicado 2021
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2530por Liu, Yang, Liu, Jianying, Zou, Jing, Ren, Ping, Weaver, Scott C., Xie, Xuping, Shi, Pei-Yong“…The rank of neutralizing titers against different heterologous variants varied, depending on the immunized variant spikes. …”
Publicado 2021
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2531por Fukuta, Mizuki, Nguyen, Co Thach, Nguyen, Thi Thu Thuy, Nguyen, Thi Thanh Ngan, Vu, Thi Bich Hau, Takemura, Taichiro, Nguyen, Le Khanh Hang, Inoue, Shingo, Morita, Kouichi, Le, Thi Quynh Mai, Hasebe, Futoshi, Moi, Meng Ling“…Infectivity and neutralizing antibody titers of flavivirus and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) are frequently measured using the conventional plaque assay. …”
Publicado 2021
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2532por Miyashita, Yusuke, Yoshida, Takanobu, Takagi, Yuriko, Tsukamoto, Hirotake, Takashima, Ken, Kouwaki, Takahisa, Makino, Katsunari, Fukushima, Satoshi, Nakamura, Kimitoshi, Oshiumi, Hiroyuki“…Local adverse reactions after the second dose, such as local pain and swelling, were less correlated with those of systemic symptoms, such as fever and muscle pain, whereas serum TNF-α levels were associated with systemic adverse reactions and with specific antibody titers. Interestingly, EV miR-92a-2-5p levels in sera were negatively correlated with degrees of adverse reactions, and EV miR-148a levels were associated with specific antibody titers. …”
Publicado 2022
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2533por Uwamino, Yoshifumi, Yokoyama, Takashi, Shimura, Takako, Nishimura, Tomoyasu, Sato, Yasunori, Wakui, Masatoshi, Kosaki, Kenjiro, Hasegawa, Naoki, Murata, Mitsuru“…The geometric mean neutralization titers measured for the original and R.1 lineages were equivalent (91.90 ± 2.40 and 102.67 ± 2.28, respectively), whereas a low titer was measured for the beta variant (18.03 ± 1.92). …”
Publicado 2022
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2534por Mantus, Grace, Nyhoff, Lindsay E., Edara, Venkata-Viswanadh, Zarnitsyna, Veronika I., Ciric, Caroline R., Flowers, Maria W., Norwood, Carson, Ellis, Madison, Hussaini, Laila, Manning, Kelly E., Stephens, Kathy, Anderson, Evan J., Ahmed, Rafi, Suthar, Mehul S., Wrammert, Jens“…The magnitude of the humoral responses to vaccination strongly correlates with responses to initial SARS-CoV-2 infection. Neutralization titers are lower against SARS-CoV-2 variants in both recovered and naive vaccinees, with titers more reduced in naive recipients. …”
Publicado 2022
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2535“…It presents significantly reduced susceptibility to antibody neutralization: after 2 doses of mRNA-vaccine, neutralizing titers to Omicron are 41 to 84 times lower than neutralization titers to D614G. …”
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2536por Tomasi, Lisa, Thiriard, Anais, Heyndrickx, Leo, Georges, Daphnée, Van den Wijngaert, Sigi, Olislagers, Véronique, Sharma, Shilpee, Matagne, André, Ackerman, Margaret E, Ariën, Kevin K, Goetghebuer, Tessa, Marchant, Arnaud“…RESULTS: Younger children had higher titers of antibodies to SARS-CoV-2 receptor binding domain (RBD), S1 but not S2 domain, and total spike (S) protein, higher avidity RBD immunoglobulin G, and higher titers of neutralizing and complement-activating antibodies as compared with older children. …”
Publicado 2022
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2537“…The results also failed entirely to conform to the agglutination titer of the sera tested and to be affected by the different type forms of the meningococci. …”
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2538“…We found anti-CCP positivity and rheumatoid factor positivity and high titers in all patients, positive anti- anti-SSA in one patient, and positive anti- anti-Sm in one patient. …”
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2539por Ng, Dianna L., Goldgof, Gregory M., Shy, Brian R., Levine, Andrew G., Balcerek, Joanna, Bapat, Sagar P., Prostko, John, Rodgers, Mary, Coller, Kelly, Pearce, Sandy, Franz, Sergej, Du, Li, Stone, Mars, Pillai, Satish K., Sotomayor-Gonzalez, Alicia, Servellita, Venice, Martin, Claudia Sanchez San, Granados, Andrea, Glasner, Dustin R., Han, Lucy M., Truong, Kent, Akagi, Naomi, Nguyen, David N., Neumann, Neil M., Qazi, Daniel, Hsu, Elaine, Gu, Wei, Santos, Yale A., Custer, Brian, Green, Valerie, Williamson, Phillip, Hills, Nancy K., Lu, Chuanyi M., Whitman, Jeffrey D., Stramer, Susan, Wang, Candace, Reyes, Kevin, Hakim, Jill M.C., Sujishi, Kirk, Alazzeh, Fariba, Pham, Lori, Oon, Ching-Ying, Miller, Steve, Kurtz, Theodore, Hackett, John, Simmons, Graham, Busch, Michael P., Chiu, Charles Y.“…We additionally describe the longitudinal dynamics of immunoglobulin-G, immunoglobulin-M, and in vitro neutralizing antibody titers in COVID-19 patients. Neutralizing antibodies rise in tandem with immunoglobulin levels following symptom onset, exhibiting median time to seroconversion within one day of each other, and there is >93% positive percent agreement between detection of immunoglobulin-G and neutralizing titers.…”
Publicado 2020
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2540por Billon-Denis, Emmanuelle, Ferrier-Rembert, Audrey, Garnier, Annabelle, Cheutin, Laurence, Vigne, Clarisse, Tessier, Emilie, Denis, Jessica, Badaut, Cyril, Rougeaux, Clémence, Depeille Wuille, Anne, Timera, Hawa, Boutin, Laet itia, Drouet, Isabelle, Verguet, Noémie, Nolent, Flora, Gorgé, Olivier, Ferraris, Olivier, Tournier, Jean-Nicolas“…CASE: One patient presented a strong IgG anti-receptor-binding domain immune response correlated with a low and rapidly decreasing titer of neutralizing antibodies. The other patient had a similar strong IgG anti-receptor-binding domain immune response but high neutralizing antibody titers. …”
Publicado 2021
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