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2641por Sheng, Wang-Huei, Chang, Sui-Yuan, Hsieh, Ming-Ju, Ieong, Si-Man, Chang, Shan-Chwen“…We recruited 100 adult participants to receive a prime adenoviral vectored vaccine (ChAdOx1, AstraZeneca) and a boost mRNA vaccine (mRNA-1273, Moderna) 12 weeks apart and checked their serum SARS-CoV-2 anti-spike IgG titers and neutralizing antibody titers against B.1.1.7 (alpha) and B.1.617.2 (delta) variants on the 28(th) day after the boost dose. …”
Publicado 2023
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2642por Halfmann, Peter J., Kuroda, Makoto, Armbrust, Tammy, Theiler, James, Balaram, Ariane, Moreno, Gage K., Accola, Molly A., Iwatsuki-Horimoto, Kiyoko, Valdez, Riccardo, Stoneman, Emily, Braun, Katarina, Yamayoshi, Seiya, Somsen, Elizabeth, Baczenas, John J., Mitamura, Keiko, Hagihara, Masao, Adachi, Eisuke, Koga, Michiko, McLaughlin, Matthew, Rehrauer, William, Imai, Masaki, Yamamoto, Shinya, Tsutsumi, Takeya, Saito, Makoto, Friedrich, Thomas C., O’Connor, Shelby L., O’Connor, David H., Gordon, Aubree, Korber, Bette, Kawaoka, Yoshihiro“…We observed reduced neutralizing antibody titers against the B.1.621 variant (3.4 to 7-fold reduction, depending on the serum sample and time after the second vaccination) compared to the early isolate and a similar reduction when compared to B.1.351. …”
Publicado 2022
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2643por Lima, Karina, Fontoura, Julia C., de Souza, Priscila Oliveira, Fazolo, Tiago, Hilario, Gabriel, Zorzetto, Renata, Rodrigues Junior, Luiz C, Coimbra, Lais D., Borin, Alexandre, Bispo-dos-Santos, Karina, Granja, Fabiana, Marques, Rafael Elias, Zavaglia, Gabriela Oliveira, Fernandes, Ingrid Rodrigues, Varela, Fernanda Hammes, Polese-Bonatto, Marcia, Tonini, Maiko Luís, Ikeda do Carmo, Greice Madeleine, de Almeida, Walquiria Aparecida Ferreira, Borges, Thiago J., Nakaya, Helder I., Proenca-Modena, José Luiz, Callegari-Jacques, Sidia Maria, Scotta, Marcelo Comerlato, Stein, Renato T., Bonorino, Cristina“…Children’s anti-N, but not anti-S, antibody titers increase over time. Neutralization titers correlate with N-specific antibodies and CD8(+)T cells. …”
Publicado 2022
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2644por Carruthers, David N., Kim, Jinho, Mendez-Perez, Daniel, Monroe, Eric, Myllenbeck, Nick, Liu, Yuzhong, Davis, Ryan W., Sundstrom, Eric, Lee, Taek Soon“…Although prenyl and isoprenyl lactate titers were limited to 1.48 ± 0.41 mg/L and 5.57 ± 1.36 mg/L, strains engineered for prenyl and isoprenyl acetate attained titers of 176.3 ± 16.0 mg/L and 3.08 ± 0.27 g/L, respectively. …”
Publicado 2023
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2646por Yamamoto, Shohei, Oshiro, Yusuke, Inamura, Natsumi, Nemoto, Takashi, Horii, Kumi, Okudera, Kaori, Konishi, Maki, Ozeki, Mitsuru, Mizoue, Tetsuya, Sugiyama, Haruhito, Aoyanagi, Nobuyoshi, Sugiura, Wataru, Ohmagari, Norio“…METHODS: Throughout the pandemic, we evaluated the anti-spike IgG antibody titers of 2- and 3-dose mRNA vaccine recipients over time among the staff of a medical and research center in Tokyo. …”
Publicado 2023
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2647por Martel, Fabiola, Cuervo-Rojas, Juliana, Ángel, Juana, Ariza, Beatriz, González, John Mario, Ramírez-Santana, Carolina, Acosta-Ampudia, Yeny, Murcia-Soriano, Luisa, Montoya, Norma, Cardozo-Romero, Claudia Cecilia, Valderrama-Beltrán, Sandra Liliana, Cepeda, Magda, Castellanos, Julio César, Gómez-Restrepo, Carlos, Perdomo-Celis, Federico, Gazquez, Andreu, Dickson, Alexandria, Brien, James D., Mateus, José, Grifoni, Alba, Sette, Alessandro, Weiskopf, Daniela, Franco, Manuel A.“…COVID-19 vaccines induced an increase in antibody titers 15-30 days after receiving the second dose, but these levels decreased at 6 months. …”
Publicado 2023
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2648por Fonseca, Francisco Noé, Haach, Vanessa, Bellaver, Franciana Volpato, Bombassaro, Gabrielly, Gava, Danielle, da Silva, Luciano Paulino, Baron, Lana Flavia, Simonelly, Mayara, Carvalho, Wanessa Araújo, Schaefer, Rejane, Bastos, Ana Paula“…RESULTS: Only intramuscular vaccination induced high hemagglutination inhibition (HI) titers. Seroconversion and seroprotection (> 4-fold rise in HI antibody titers, reaching a titer of ≥ 1:40) were achieved in 80% of mice (intramuscularly vaccinated group) at 21 days after booster immunization. …”
Publicado 2023
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2649por Straub, Christopher T., Bing, Ryan G., Wang, Jack P., Chiang, Vincent L., Adams, Michael W. W., Kelly, Robert M.“…RESULTS: Of the 17 transgenic poplar lines examined with C. bescii, a wide variation in solubilization and fermentation titer was observed. While the wild type poplar control demonstrated relatively high recalcitrance with a total solubilization of only 20% and a fermentation titer of 7.3 mM, the transgenic lines resulted in solubilization ranging from 15 to 79% and fermentation titers from 6.8 to 29.6 mM. …”
Publicado 2020
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2650“…K. aridum produces three components A82846A, B and C, so it is essential to increase A82846B titer and reduce A82846A and C titers by overexpressing halogenase and glycosyltransferase genes. …”
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2651por Li, Can, Chen, Yan-Xia, Liu, Fei-Fei, Lee, Andrew Chak-Yiu, Zhao, Yan, Ye, Zhan-Hong, Cai, Jian-Piao, Chu, Hin, Zhang, Rui-Qi, Chan, Kwok-Hung, Chiu, Kelvin Hei-Yeung, Lung, David Christopher, Sridhar, Siddharth, Hung, Ivan Fan-Ngai, To, Kelvin Kai-Wang, Zhang, Anna Jin-Xia, Chan, Jasper Fuk-Woo, Yuen, Kwok-Yung“…Significantly higher serum titer of fluorescent foci microneutralization inhibition antibody was detected in D1 and D2 vaccinated hamsters at day 4 post-challenge compared to controls despite undetectable neutralizing antibody titer. …”
Publicado 2021
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2652por Lindemann, Monika, Lenz, Veronika, Knop, Dietmar, Klump, Hannes, Alt, Mira, Aufderhorst, Ulrich W., Schipper, Leonie, Schwarzkopf, Sina, Meller, Lara, Steckel, Nina, Koldehoff, Michael, Heinold, Andreas, Heinemann, Falko M., Fischer, Johannes, Hutschenreuter, Gabriele, Knabbe, Cornelius, Dolff, Sebastian, Brenner, Thorsten, Dittmer, Ulf, Witzke, Oliver, Herbstreit, Frank, Horn, Peter A., Krawczyk, Adalbert“…RESULTS: Donor sera had on average lower IgG antibody ratios and neutralizing titers than the COVID‐19 patients before the onset of treatment (median ratio of 5.8 and neutralizing titer of 1:320 vs. 7.5 and 1:640, respectively). …”
Publicado 2021
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2653por Morimoto, Keita, Kanzaki, Go, Niikura, Takahito, Koike, Kentaro, Matsuo, Nanae, Maruyama, Yukio, Tsuboi, Nobuo, Yokoo, Takashi“…The patient demonstrated a positive titer for MPO-ANCA (192 IU/mL) and a positive drug-induced lymphocyte stimulation test for cimetidine. …”
Publicado 2021
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2654“…RESULTS: In this study, we first constructed an engineered E. coli cell factory for producing LNT II from N-acetylglucosamine (GlcNAc) feedstock, a monomer of chitin, by introducing heterologous β-1,3-acetylglucosaminyltransferase, resulting in a LNT II titer of 0.12 g L(−1). Then, lacZ (lactose hydrolysis) and nanE (GlcNAc-6-P epimerization to ManNAc-6-P) were inactivated to further strengthen the synthesis of LNT II, and the titer of LNT II was increased to 0.41 g L(−1). …”
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2655por Choudhary, Hari Ram, Parai, Debaprasad, Chandra Dash, Girish, Kshatri, Jaya Singh, Mishra, Narayan, Choudhary, Prasanta Kumar, Pattnaik, Dipti, Panigrahi, Kumudini, Behera, Susmita, Ranjan Sahoo, Nihar, Podder, Sreeparna, Mishra, Adyasha, Raghav, Sunil Kumar, Mishra, Sanjeeb Kumar, Pradhan, Subrat Kumar, Sahoo, Subrat Kumar, Pattnaik, Matrujyoti, Rout, Usha Kiran, Nanda, Rashmi Ranjan, Mondal, Nityananda, Kanungo, Srikanta, Palo, Subrata Kumar, Bhattacharya, Debdutta, Pati, Sanghamitra“…Covishield recipients produced higher median anti-S IgG titer than Covaxin. No statistically significant differences in antibody titers were observed based on age, gender, comorbidities, and blood groups. …”
Publicado 2021
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2656por Lapp, Stacey A, Abrams, Joseph, Lu, Austin T, Hussaini, Laila, Kao, Carol M, Hunstad, David A, Rosenberg, Robert B, Zafferani, Marc J, Ede, Kaleo C, Ballan, Wassim, Laham, Federico R, Beltran, Yajira, Hsiao, Hui-Mien, Sherry, Whitney, Jenkins, Elan, Jones, Kaitlin, Horner, Anna, Brooks, Alyssa, Bryant, Bobbi, Meng, Lu, Hammett, Teresa A, Oster, Matthew E, Bamrah-Morris, Sapna, Godfred-Cato, Shana, Belay, Ermias, Chahroudi, Ann, Anderson, Evan J, Jaggi, Preeti, Rostad, Christina A“…RESULTS: Children with MIS-C had significantly higher SARS-CoV-2 RBD IgG than children with acute COVID-19 (median, 2783 vs 146; P < .001), and titers correlated with nucleocapsid IgG. For patients with MIS-C, RBD IgG titers declined in convalescence (median, 2783 vs 1135; P = .010) in contrast to patients with COVID-19 (median, 146 vs 4795; P < .001). …”
Publicado 2022
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2657por Shapiro Ben David, Shirley, Mizrahi, Barak, Rahamim-Cohen, Daniella, Supino-Rosin, Lia, Shahar, Arnon, Hermoni-Alon, Sharon, Fremder Sacerdote, Ariela, Irony, Angela, Lazar, Rachel, Kalkstein, Nir, Lustig, Yaniv, Indenbaum, Victoria, Landsberger, Daniel, Mizrahi-Reuveni, Miri, Shapira, Shirley“…Per individual SARS-CoV-2 Spike IgG titer ratios were calculated one month after the booster administration compared to titers one month following the second dose and prior to booster. …”
Publicado 2022
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2658por Xu, Shiwei, Carpenter, Margaret C., Spreng, Rachel L., Neidich, Scott D., Sarkar, Sharanya, Tenney, DeAnna, Goodman, Derrick, Sawant, Sheetal, Jha, Shalini, Dunn, Brooke, Juliana McElrath, M., Bekker, Valerie, Mudrak, Sarah V., Flinko, Robin, Lewis, George K., Ferrari, Guido, Tomaras, Georgia D., Shen, Xiaoying, Ackerman, Margaret E.“…Analysis of trials of partially effective HIV vaccines have identified features of the immune response that correlate with decreased risk, including high titers of V1V2-binding IgG and IgG3 responses with low titers of V1V2-binding IgA responses and enhanced Fc effector functions, notably antibody-dependent cellular cytotoxicity (ADCC) and antibody-dependent cellular phagocytosis (ADCP). …”
Publicado 2022
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2659por Widysanto, Allen, Prasetya, Ignatius Bima, Meriyanti, Tandry, Sungono, Veli, Setiawan, Diane Lukito, Gunawan, Edy, Adiputra, Bayu, Lorens, Jane Olivia, Santi, Theresia, Pradhana, Cindy Meidy Leony, Yusuf, Irawan, Gunawan, Catherine“…CONCLUSIONS: The third dose of vaccine increased the quantitative SARS-CoV-2 spike IgG antibody titers and eliminated differences in antibodies titer by gender.…”
Publicado 2022
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2660por Otoupal, Peter B., Geiselman, Gina M., Oka, Asun M., Barcelos, Carolina A., Choudhary, Hemant, Dinh, Duy, Zhong, Wenqing, Hwang, HeeJin, Keasling, Jay D., Mukhopadhyay, Aindrila, Sundstrom, Eric, Haushalter, Robert W., Sun, Ning, Simmons, Blake A., Gladden, John M.“…RESULTS: Introduction of the 2-pyrone synthase gene into R. toruloides enabled the organism to produce 2.4 g/L TAL from simple media or 2.0 g/L from hydrolysate produced from sorghum biomass. Both of these titers are on par with titers from other better-studied microbial hosts after they had been heavily engineered. …”
Publicado 2022
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